Human immunodeficiency virus type 1 (HIV-1)-induced GRO-α production stimulates HIV-1 replication in macrophages and T lymphocytes

Journal of Virology

Volumn 75, Issue 13, 2001, Pages 5812-5822

  Lane, B R ^a   Strieter, R M ^a   Coffey, M J ^a   Markovitz, D M ^a  

^a 5220 MSRB III ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CHEMOKINE RECEPTOR CXCR1; GLYCOPROTEIN GP 120; PROTEIN GRO ALPHA; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; GENE ACTIVATION; GROWTH REGULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; NONHUMAN; NORMAL HUMAN; ONCOGENE; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN SYNTHESIS; T LYMPHOCYTE; VIRUS REPLICATION;

CHEMOKINES, CXC; CHEMOTACTIC FACTORS; GROWTH SUBSTANCES; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MACROPHAGES; RECEPTORS, CXCR4; RECEPTORS, INTERLEUKIN-8B; T-LYMPHOCYTES; VIRUS REPLICATION;

EID: 0034978985     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.13.5812-5822.2001     Document Type: Article

References (63)

1. The CXC chemokines growth-regulated oncogene (GRO)α, GROβ, GROγ, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor
2. CC CKR5: A RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1
3. HIV coreceptor downregulation as antiviral principle: SDF-1α-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication
4. Constitutive overexpression of a growth-regulated gene in transformed Chinese hamster and human cells
5. + T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor
6. G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator
7. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
8. Induction of interleukin-10 by human immunodeficiency virus type I and its gp120 protein in human monocytes/macrophages
9. Macrophage inflammatory protein-1α is induced by human immunodeficiency virus infection of monocyte-derived macrophages
10. CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nef
11. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
12. The HIV-1 gp120 envelope protein has the intrinsic capacity to stimulate monokine secretion
13. + T cells
14. RANTES inhibits HIV-1 replication in human peripheral blood monocytes and alveolar macrophages
15. HIV's evasion of the cellular immune response
16. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals
17. Identification of a major co-receptor for primary isolates of HIV-1
18. Increased replication of T-cell-tropic HIV strains and CXC-chemokine receptor-4 induction in T cells treated with macrophage inflammatory protein (MIP)-1α, MIP-1β and RANTES beta-chemokines
19. A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors
20. + cells is mediated by the chemokine receptor CC-CKR-5
21. Spontaneous mutations in the env gene of the human immunodeficiency virus type 1 NDK isolate are associated with a CD4-independent entry phenotype
22. CD4-independent infection by HIV-2 is mediated by fusin/CXCR4
23. A sensitive ELISA for the detection of human monocyte chemoattractant protein-1 (MCP-1)
24. AIDS: Immunopathogenic mechanisms and research strategies
25. HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
26. HIV infection and dementia
27. The role of mononuclear phagocytes in HTLV-III/LAV infection
28. Chemokines activate Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor in mammalian cells in culture
29. MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions
30. Enhancement of human immunodeficiency virus type 1 infection by the CC-chemokine RANTES is independent of the mechanism of virus-cell fusion
31. HIV-1 induces turnout necrosis factor and IL-1 gene expression in primary human macrophages independent of productive infection
32. + T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4
33. T cell-tropic HIV gp120 mediates CD4 and CD8 cell chemotaxis through CXCR4 independent of CD4: Implications for HIV pathogenesis
34. + T cells: Role of signal transduction
35. Reduced binding and phagocytosis of Pneumocystis carinii by alveolar macrophages from persons infected with HIV-1 correlates with mannose receptor down regulation
36. TNF-alpha inhibits HIV-1 replication in peripheral blood monocytes and alveolar macrophages by inducing the production of RANTES and decreasing C-C chemokine receptor 5 (CCR5) expression
37. Chemokine receptors: Keys to AIDS pathogenesis?
38. Mechanism and biological significance of constitutive expression of MGSA/GRO chemokines in malignant melanoma tumor progression
39. Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: A novel inhibitory mechanism of HIV infectivity
40. Opposite effects of SDF-1 on human immunodeficiency virus type 1 replication
41. Role of mononuclear phagocytes in the pathogenesis of human immunodeficiency virus infection
42. Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor
43. Exposure to bacterial products renders macrophages highly susceptible to T-tropic HIV-1
44. Neutrophil-activating properties of the melanoma growth-stimulatory activity
45. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
46. Identification of HIV-1 envelope glycoprotein in the serum of AIDS and ARC patients
47. Replication of HIV-1 in primary, monocyte cultures
48. Purification of melanoma growth stimulatory activity
49. Human immunodeficiency virus type 1 T-lymphotropic strains enter macrophages via a CD4- and CXCR4-mediated pathway: Replication is restricted at a postentry level
50. Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: Implications for recruitment of leukocytes into brain and lymph nodes
51. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population
52. Modulation of the effector function of human monocytes for Mycobacterium avium by human immunodeficiency virus-1 envelope glycoprotein gp120
53. CXCR4 as a functional coreceptor for human immunodeficiency virus type 1 infection of primary macrophages
54. The functional role of the ELR motif in CXC chemokine-mediated angiogenesis
55. CD4-dependent, antibody-sensitive interactions between HIV-1 and its coreceptor CCR-5
56. The CC-chemokine RANTES increases the attachment of human immunodeficiency virus type 1 to target cells via glycosaminoglycans and also activates a signal transduction pathway that enhances viral infectivity
57. CXCR4 is a functional coreceptor for infection of human macrophages by CXCR4-dependent primary HIV-1 isolates
58. GRO alpha and interleukin-8 in Pneumocystis carinii or bacterial pneumonia and adult respiratory distress syndrome
59. Chemokines and T lymphocytes: More than an attraction
60. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5
61. Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia
62. Genotypic and phenotypic characterization of HIV-1 patients with primary infection