Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia

Journal of Neuroimmunology

Volumn 98, Issue 2, 1999, Pages 185-200

  Zheng, Jialin ^a   Thylin, Michael R ^a   Ghorpade, Anuja ^a   Xiong, Huangui ^a   Persidsky, Yuri ^a   Cotter, Robin ^a   Niemann, Douglas ^a   Che, Myhanh ^a   Zeng, Yong Chun ^a   Gelbard, Harris A ^b   Shepard, Robin B ^a   Swartz, Jennifer M ^a   Gendelman, Howard E ^a,c  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

CXCR4; GTP binding protein; HIV 1 associated dementia; Monocyte derived macrophages; Neuronal apoptosis

Indexed keywords

CALCIUM; CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DEMENTIA; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOCYTOCHEMISTRY; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

AIDS DEMENTIA COMPLEX; ANIMALS; APOPTOSIS; ASTROCYTES; CALCIUM; CELL NUCLEUS; CELLS, CULTURED; CHEMOKINES, CXC; EXCITATORY POSTSYNAPTIC POTENTIALS; FETUS; GENE EXPRESSION; HIPPOCAMPUS; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; IN SITU NICK-END LABELING; MACROPHAGES; MICROSCOPY, ELECTRON; MONOCYTES; NEURONS; OLIGONUCLEOTIDE PROBES; RATS; RECEPTORS, CXCR4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

EID: 0033046019     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(99)00049-1     Document Type: Article

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