Inhibition of natural killer cell activation signals by killer cell immunoglobulin-like receptors (CD158)

Immunological Reviews

Volumn 181, Issue , 2001, Pages 223-233

  Long, Eric O ^a   Barber, Domingo F ^a   Burshtyn, Deborah N ^b   Faure, Mathias ^a   Peterson, Mary ^a   Rajagopalan, Sumati ^a   Renard, Valéry ^c   Sandusky, Mina ^a   Stebbins, Christopher C ^a   Wagtmann, Nicolai ^d   Watzl, Carsten ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

^c M and E AIS   (Denmark)

^d NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

2B4 RECEPTOR; CD158 ANTIGEN; IMMUNOGLOBULIN RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN KIR3DL7; UNCLASSIFIED DRUG;

CELL ACTIVATION; CELL CONTACT; CELL FUNCTION; CYTOTOXICITY; DEPHOSPHORYLATION; GENE SEQUENCE; MAJOR HISTOCOMPATIBILITY COMPLEX; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; TARGET CELL;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KILLER CELLS, NATURAL; MEMBRANE GLYCOPROTEINS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, IMMUNOLOGIC; SEQUENCE HOMOLOGY, AMINO ACID; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION;

EID: 0034904147     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-065X.2001.1810119.x     Document Type: Review

References (77)

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11. Inhibitory MHC class I receptors on NK and T cells: A standard nomenclature
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13. Direct binding and functional transfer of NK cell inhibitory receptors reveal novel patterns of HLA-C allotype recognition
14. The role of zinc in the binding of killer cell Ig-like receptors to class I MHC proteins
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16. The natural killer cell receptor specific for HLA-A allotypes: A novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer
17. DAP10 and DAP12 form distinct, but functionally cooperative, receptor complexes in natural killer cells
18. Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules
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28. Isotypic variation of novel immunoglobulin-like transcript/killer cell inhibitory receptor loci in the leukocyte receptor complex
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30. Short KIR haplotypes in pygmy chimpanzee (Bonobo) resemble the conserved framework of diverse human KIR haplotypes
31. Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I
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33. Major histocompatibility complex class I molecules modulate activation threshold and early signaling of T cell antigen receptor-γ/δ stimulated by nonpeptidic ligands
34. NK cell inhibitory receptors prevent tyrosine phosphorylation of the activation receptor 2B4 (CD244)
35. Reconstituted killer cell inhibitory receptors for major histocompatibillty complex class I molecules control mast cell activation induced via immunoreceptor tyrosine-based activation motifs
36. Crystal structure of the tyrosine phosphatase SHP-2
37. The human natural killer cell immune synapse
38. The Ig-related killer cell inhibitory receptor binds zinc and requires zinc for recognition of HLA-C on target cells
39. Zinc bound to the killer cell-inhibitory receptor modulates the negative signal in human NK cells
40. Cobalt-mediated dimerization of the human natural killer cell inhibitory receptor
41. Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2
42. Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand
43. Direct binding of a soluble natural killer cell inhibitory receptor to a soluble human leukocyte antigen-Cw4 class I major histocompatibility complex molecule
44. Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor
45. A novel phosphotyrosine motif with a critical amino acid at position-2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP- 1
46. Conserved residues amino-terminal of cytoplasmic tyrosines contribute to the SHP-1-mediated inhibitory function of killer cell Ig-like receptors
47. Type I transmembrane receptor with inhibitory function in mouse mast cells and NK cells
48. gp49B1 inhibits IgE-initiated mast cell activation through both immunoreceptor tyrosine-based inhibitory motifs, recruitment of src homology 2 domain-containing phosphatase-1, and suppression of early and late calcium mobilization
49. The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1
50. Development of Lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
51. Sequential involvement of Lck and SHP-1 with MHC-recognizing receptors on NK cells inhibits FcR-initiated tyrosine kinase activation
52. Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase
53. Requirement of SH2-containing protein tyrosine phosphatases SHP-1 and SHP-2 for paired immunoglobulin-like receptor B (PIR-B)-mediated inhibitory signal
54. Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases
55. Differential roles of N- and C-terminal immunoreceptor tyrosine-based inhibition motifs during inhibition of cell activation by killer cell inhibitory receptors
56. Adhesion to target cells is disrupted by the killer cell inhibitory receptor
57. Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity
58. SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors
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60. Essential role of LAT in T cell development
61. NK cytokine secretion and cytotoxicity occur independently of the SLP-76 adaptor protein
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66. Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1
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71. Patients with X-linked lymphoproliferative disease have a defect in 2B4 receptor-mediated NK cell cytotoxicity
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73. Functional requirement for SAP in 2B4-mediated activation of human natural killer cells as revealed by the X-linked lymphoproliferative syndrome
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76. Signaling takes shape in the immune system
77. TCR, LFA-1, and CD28 play unique and complementary roles in signaling T cell cytoskeletal reorganization