Direct binding and functional transfer of NK cell inhibitory receptors reveal novel patterns of HLA-C allotype recognition

Journal of Immunology

Volumn 161, Issue 2, 1998, Pages 571-577

  Winter, Christine C ^a   Gumperz, Jenny E ^b,c   Parham, Peter ^b   Long, Eric O ^a   Wagtmann, Nicolai ^a,d  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b STANFORD UNIVERSITY   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ASPARAGINE; HLA ANTIGEN CLASS 1; HLA C ANTIGEN; HYBRID PROTEIN; IMMUNOGLOBULIN RECEPTOR; PHENYLALANINE; SERINE; T LYMPHOCYTE RECEPTOR; TYROSINE;

ALLOTYPE; AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; HUMAN; HUMAN CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; VACCINIA VIRUS;

ALLELES; AMINO ACID SUBSTITUTION; HLA-C ANTIGENS; HUMANS; KILLER CELLS, NATURAL; MUTAGENESIS, SITE-DIRECTED; PHENYLALANINE; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; RECOMBINANT FUSION PROTEINS; SOLUBILITY; TRANSFECTION;

EID: 0032528340     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Parham, P. 1997. NK cells, MHC class I antigens and missing self. Immunol. Rev. 155:5.
2. Lanier, L. L. 1997. Natural killer cells: from no receptors to too many. Immunity 6:371.
3. Wagtmann, N., R. Biassoni, C. Cantoni, S. Verdiani, M. Malnati, M. Vitale, C. Bottino, L. Moretta, A. Moretta, and E. O. Long. 1995. Molecular clones of the p58 natural killer cell receptor reveal Ig-related molecules with diversity in both the extra- and intracellular domains. Immunity 2:439.
4. Valiante, N. M., M. Uhrberg, H. G. Shilling, K. Lienert-Weidenbach, K. L. Arnett, A. D'Andrea, J. H. Phillips, L. L. Lanier, and P. Parham. 1997. Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity 7:739.
5. Braud, V. M., D. S. J. Allan, C. A. O'Callaghan, K. Söderström, A. D'Andrea, G. S. Ogg, S. Lazetic, N. T. Young, J. I. Bell, J. H. Phillips, L. L. Lanier, and A. J. McMichael. 1998. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 391:795.
6. Litwin, V., J. Gumperz, P. Parham, J. H. Phillips, and L. L. Lanier. 1993. Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type. J. Exp. Med. 178:1321.
7. Ciccone, E., D. Pende, O. Viale, A. Than, C. Di Donato, A. M. Orengo, R. Biassoni, S. Verdiani, A. Amoroso, A. Moretta, and L. Moretta. 1992. Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2). J. Exp. Med. 176:963.
8. Colonna, M., T. Spies, J. L. Strominger, E. Ciccone, A. Moretta, L. Moretta, D. Pende, and O. Viale. 1992. Alloantigen recognition by two human natural killer cell clones is associated with HLA-C or a closely linked gene. Proc. Natl. Acad. Sci. USA 89:7983.
9. Moretta, A., M. Vitale, C. Bottino, A. M. Orengo, L. Morelli, R. Augugliaro, M. Barbaresi, E. Ciccone, and L. Moretta. 1993. P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells: anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities. J. Exp. Med. 178:597.
10. Colonna, M., G. Borsellino, M. Falco, G. B. Ferrara, and J. L. Strominger. 1993. HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells. Proc. Natl. Acad. Sci. USA 90:12000.
11. Colonna, M., and J. Samaridis. 1995. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science 268:405.
12. Burshtyn, D. N., A. M. Scharenberg, N. Wagtmann, S. Rajagopalan, K. Berrada, T. Yi, J. P. Kinet, and E. O. Long. 1996. Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor. Immunity 4:77.
13. Moretta, A., S. Sivori, M. Vitale, D. Pende, L. Morelli, R. Augugliaro, C. Bottino, and L. Moretta. 1995. Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. J. Exp. Med. 182: 875.
14. Biassoni, R., C. Cantoni, M. Falco, S. Verdiani, C. Bottino, M. Vitale, R. Conte, A. Poggi, A. Moretta, and L. Moretta. 1996. The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions. J. Exp. Med. 183:645.
15. Mandelboim, O., D. M. Davis, H. T. Reyburn, M. Valés-G-mez, E. G. Sheu, L. Pazmany, and J. L. Strominger. 1996. Enhancement of class II-restricted T cell responses by costimulatory NK receptors for class I MHC proteins. Science 274: 2097.
16. Wagtmann, N., S. Rajagopalan, C. C. Winter, M. Peruzzi, and E. O. Long. 1995. Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer. Immunity 3:801.
17. Fan, Q. R., D. N. Garboczi, C. C. Winter, N. Wagtmann, E. O. Long, and D. C. Wiley. 1996. Direct binding of a soluble natural killer cell inhibitory receptor to a soluble human leukocyte antigen-Cw4 class I major histocompatibility complex molecule. Proc. Natl. Acad. Sci. USA 93:7178.
18. Winter, C. C., and E. O. Long. 1997. A single amino acid in the p58 killer cell inhibitory receptor controls the ability of natural killer cells to discriminate between the two groups of HLA-C allotypes. J. Immunol. 158:4026.
19. Dohring, C., and M. Colonna. 1996. Human natural killer cell inhibitory receptors bind to HLA class I molecules. Eur. J. Immunol. 26:365.
20. Biassoni, R., A. Pessino, A. Malaspina, C. Cantoni, C. Bottino, S. Sivori, L. Moretta, and A. Moretta. 1997. Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules. Eur. J. Immunol. 27:3095.
21. Kim, J., Y. J. Chwae, M. Y. Kim, I. H. Choi, J. H. Park, and S. J. Kim. 1997. Molecular basis of HLA-C recognition by p58 natural killer cell inhibitory receptors. J. Immunol. 159:3875.
22. Shimizu, Y., and R. DeMars. 1989. Production of human cells expressing individual transferred HLA-A,-B,-C genes using an HLA-A,-B,-C null human cell line. J. Immunol. 142:3320.
23. Gong, J. H., G. Maki, and H. G. Klingemann. 1994. Characterization of a human cell line (NK-92) with phenotypical and functional characteristics of activated natural killer cells. Leukemia 8:652.
24. Earl, P. L., and B. Moss. 1988. Generation of recombinant vaccinia viruses. In Current Protocols in Molecular Biology. F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl, eds. John Wiley & Sons, New York, p. 16.17.1.
25. Aruffo, A., I. Stamenkovic, M. Melnick, C. B. Underbill, and B. Seed. 1990. CD44 is the principal cell surface receptor for hyaluronate. Cell 61:1303.
26. Peruzzi, M., N. Wagtmann, and E. O. Long. 1996. A p70 killer cell inhibitory receptor specific for several HLA-B allotypes discriminates among peptides bound to HLA-B*2705. J. Exp. Med. 184:1585.
27. Malnati, M. S., P. Lusso, E. Ciccone, A. Moretta, L. Moretta, and E. O. Long. 1993. Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements. J. Exp. Med. 178:961.
28. Biassoni, R., M. Falco, A. Cambiaggi, P. Costa, S. Verdiani, D. Pende, R. Conte, C. Di Donato, P. Parham, and L. Moretta. 1995. Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules: role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones. J. Exp. Med. 182:605.
29. Barber, L. D., L. Percival, N. M. Valiante, L. Chen, C. Lee, J. E. Gumperz, J. H. Phillips, L. L. Lanier, J. C. Bigge, R. B. Parekh, and P. Parham. 1996. The inter-locus recombinant HLA-B*4601 has high selectivity in peptide binding and functions characteristic of HLA-C. J. Exp. Med. 184:735.
30. Fan, Q. R., L. Mosyak, C. C. Winter, N. Wagtmann, E. O. Long, and D. C. Wiley. 1997. Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors. Nature 389:96.
31. Borrego, F., M. Ulbrecht, E. H. Weiss, J. E. Coligan, and A. G. Brooks. 1998. Recognition of HLA-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from NK cell mediated lysis. J. Exp. Med. 187:813.
32. Moretta, A., R. Biassoni, C. Bottino, D. Pende, M. Vitale, A. Poggi, M. C. Mingari, and L. Moretta. 1997. Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes. Immunol. Rev. 155:105.