메뉴 건너뛰기




Volumn 162, Issue 12, 1999, Pages 7181-7188

CD94/NKG2-A inhibitory complex blocks CD16-triggered Syk and extracellular regulated kinase activation, leading to cytotoxic function of human NK cells

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CD16 ANTIGEN; CD94 ANTIGEN; PROTEIN P21; TYROSINE;

EID: 0033564869     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (42)

References (48)
  • 1
    • 0024792513 scopus 로고
    • Biology of natural killer cells
    • Trinchieri, G. 1989. Biology of natural killer cells. Adv. Immunol. 47:187.
    • (1989) Adv. Immunol. , vol.47 , pp. 187
    • Trinchieri, G.1
  • 5
    • 0030848994 scopus 로고    scopus 로고
    • Signal transduction during natural killer cell activation: Inside the mind of a killer
    • Leibson, P. J. 1997. Signal transduction during natural killer cell activation: inside the mind of a killer. Immunity 6:655.
    • (1997) Immunity , vol.6 , pp. 655
    • Leibson, P.J.1
  • 6
    • 0030266705 scopus 로고    scopus 로고
    • Clonotypic differences in signaling from CD94 (kp43) on NK cells lead to divergent cellular responses
    • Brumbaugh, K. M., J. J. Perez-Viliar, C. J. Dick, R. A. Schoon, M. Lopez-Botet, and P. J. Leibson. 1996. Clonotypic differences in signaling from CD94 (kp43) on NK cells lead to divergent cellular responses. J. Immunol. 157:2804.
    • (1996) J. Immunol. , vol.157 , pp. 2804
    • Brumbaugh, K.M.1    Perez-Viliar, J.J.2    Dick, C.J.3    Schoon, R.A.4    Lopez-Botet, M.5    Leibson, P.J.6
  • 7
    • 0031888941 scopus 로고    scopus 로고
    • Signaling through human killer cell activating receptors triggers tyrosine phosphorylation of an associated protein complex
    • Campbell, K. S., M. Cella, M. Carretero, M. Lopez-Botet, and M. Colonna. 1998. Signaling through human killer cell activating receptors triggers tyrosine phosphorylation of an associated protein complex. Eur. J. Immunol. 28:599.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 599
    • Campbell, K.S.1    Cella, M.2    Carretero, M.3    Lopez-Botet, M.4    Colonna, M.5
  • 8
    • 0032510146 scopus 로고    scopus 로고
    • Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells
    • Lanier, L. L., B. C. Corliss, J. Wu, C. Leong, and J. H. Phillips. 1998. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature 391:703.
    • (1998) Nature , vol.391 , pp. 703
    • Lanier, L.L.1    Corliss, B.C.2    Wu, J.3    Leong, C.4    Phillips, J.H.5
  • 9
    • 0032100703 scopus 로고    scopus 로고
    • Association of DAP12 with activating CD94/NKg2C NK cell receptors
    • Lanier, L. L., B. Corliss, J. Wu, J. H. Phillips. 1998. Association of DAP12 with activating CD94/NKG2C NK cell receptors. Immunity 8:693.
    • (1998) Immunity , vol.8 , pp. 693
    • Lanier, L.L.1    Corliss, B.2    Wu, J.3    Phillips, J.H.4
  • 10
    • 0032526860 scopus 로고    scopus 로고
    • NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis
    • Vitale, M., C. Bottino, S. Sivori, L. Sanseverino, R. Castriconi, E. Marcenaro, R. Augugliaro, L. Moretta, and A. Moretta. 1998. NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis. J. Exp. Med. 187:2065.
    • (1998) J. Exp. Med. , vol.187 , pp. 2065
    • Vitale, M.1    Bottino, C.2    Sivori, S.3    Sanseverino, L.4    Castriconi, R.5    Marcenaro, E.6    Augugliaro, R.7    Moretta, L.8    Moretta, A.9
  • 11
    • 0032100476 scopus 로고    scopus 로고
    • Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: Identification of perforin and granzyme B mobilization by functional ERK2
    • Wei, S., A. M. Gamero, J. H. Liu, A. A. Daulton, N. I. Valkov, J. A. Trapani, A. C. Larner, M. J. Weber, and J. Y. Djeu. 1998. Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: identification of perforin and granzyme B mobilization by functional ERK2. J. Exp. Med. 187:1753.
    • (1998) J. Exp. Med. , vol.187 , pp. 1753
    • Wei, S.1    Gamero, A.M.2    Liu, J.H.3    Daulton, A.A.4    Valkov, N.I.5    Trapani, J.A.6    Larner, A.C.7    Weber, M.J.8    Djeu, J.Y.9
  • 14
    • 0030756727 scopus 로고    scopus 로고
    • Natural killer cell-target cell interactions
    • Timonen, T., and T. Helander. 1997. Natural killer cell-target cell interactions. Curr. Opin. Cell Biol. 9:667.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 667
    • Timonen, T.1    Helander, T.2
  • 17
    • 0030470555 scopus 로고    scopus 로고
    • Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits
    • Lazetic, S., C. Chang, J. P. Houchins, L. L. Lanier, and J. H. Phillips. 1996. Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits. J. Immunol. 157: 4741.
    • (1996) J. Immunol. , vol.157 , pp. 4741
    • Lazetic, S.1    Chang, C.2    Houchins, J.P.3    Lanier, L.L.4    Phillips, J.H.5
  • 19
    • 0031018766 scopus 로고    scopus 로고
    • NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor
    • Brooks, A. G., P. E. Posch, C. J. Scorzelli, F. Borrego, and J. E. Coligan. 1997. NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor. J. Exp. Med. 185:795.
    • (1997) J. Exp. Med. , vol.185 , pp. 795
    • Brooks, A.G.1    Posch, P.E.2    Scorzelli, C.J.3    Borrego, F.4    Coligan, J.E.5
  • 21
    • 0032473478 scopus 로고    scopus 로고
    • Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2-A confers protection from natural killer cell-mediated lysis
    • Borrego, F., M. Ulbrecht, E. H. Wiess, J. E. Coligan, and A. G. Brooks. 1998. Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2-A confers protection from natural killer cell-mediated lysis. J. Exp. Med. 187:813.
    • (1998) J. Exp. Med. , vol.187 , pp. 813
    • Borrego, F.1    Ulbrecht, M.2    Wiess, E.H.3    Coligan, J.E.4    Brooks, A.G.5
  • 23
    • 0030988540 scopus 로고    scopus 로고
    • The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9
    • Braud, V. M., E. Y. Jones, and A. McMichael. 1997. The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9. Eur. J. Immunol. 27:1164.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1164
    • Braud, V.M.1    Jones, E.Y.2    McMichael, A.3
  • 24
    • 0032524965 scopus 로고    scopus 로고
    • HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences
    • Lee, N., D. R. Goodlett, A. Ishitani, H. Marquardt, and D. E. Geraghty. 1998. HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences. J. Immunol. 160:4951.
    • (1998) J. Immunol. , vol.160 , pp. 4951
    • Lee, N.1    Goodlett, D.R.2    Ishitani, A.3    Marquardt, H.4    Geraghty, D.E.5
  • 25
    • 0031960065 scopus 로고    scopus 로고
    • Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: Evidence for receptor function in heterologous transfectants
    • Carretero M., G. Palmieri, M. Llano, V. Tullio, A. Santoni, D. E. Geraghty, and M. Lopez-Botet. 1998. Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: evidence for receptor function in heterologous transfectants. Eur. J. Immunol. 28:1280.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 1280
    • Carretero, M.1    Palmieri, G.2    Llano, M.3    Tullio, V.4    Santoni, A.5    Geraghty, D.E.6    Lopez-Botet, M.7
  • 26
    • 0031172446 scopus 로고    scopus 로고
    • Immunoreceptor tyrosine-based inhibitor motifs
    • Vivier, E., and M. Daeron. 1997. Immunoreceptor tyrosine-based inhibitor motifs. Immunol. Today 18:286.
    • (1997) Immunol. Today , vol.18 , pp. 286
    • Vivier, E.1    Daeron, M.2
  • 27
    • 0030696202 scopus 로고    scopus 로고
    • Regulation through inhibitory receptors: Lessons from natural killer cells
    • Burshtyn, D. N., and E. O. Long. 1997. Regulation through inhibitory receptors: lessons from natural killer cells. Trends Cell Biol. 7:473.
    • (1997) Trends Cell Biol. , vol.7 , pp. 473
    • Burshtyn, D.N.1    Long, E.O.2
  • 28
    • 0030036615 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase IC
    • Campbell, K. S., M. Dessing, M. Lopez-Botet, M. Cella, and M. Colonna. 1996. Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase IC. J. Exp. Med. 184:93.
    • (1996) J. Exp. Med. , vol.184 , pp. 93
    • Campbell, K.S.1    Dessing, M.2    Lopez-Botet, M.3    Cella, M.4    Colonna, M.5
  • 29
    • 0030457304 scopus 로고    scopus 로고
    • Killer cell inhibitory receptor recognition of human leukocyte antigen (HLA) class I blocks formation of a pp36/PLC-γ signaling complex in human natural killer (NK) cells
    • Valiante, N. M., J. H. Phillips, L. L. Lanier, and P. Parham. 1996. Killer cell inhibitory receptor recognition of human leukocyte antigen (HLA) class I blocks formation of a pp36/PLC-γ signaling complex in human natural killer (NK) cells. J. Exp. Med. 184:2243.
    • (1996) J. Exp. Med. , vol.184 , pp. 2243
    • Valiante, N.M.1    Phillips, J.H.2    Lanier, L.L.3    Parham, P.4
  • 30
    • 0029052548 scopus 로고
    • Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I
    • Kaufman, D. S., R. A. Schoon, M. J. Robertson, and P. J. Leibson. 1995. Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I. Proc. Natl. Acad. Sci. USA 92:6484.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 6484
    • Kaufman, D.S.1    Schoon, R.A.2    Robertson, M.J.3    Leibson, P.J.4
  • 32
    • 0029801052 scopus 로고    scopus 로고
    • CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: Identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies
    • Sivori, S., M. Vitale, C. Bottino, E. Marcenaro, L. Sanseverino, S. Parolini, L. Moretta, and A. Moretta. 1996. CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies. Eur. J. Immunol. 26:2487.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2487
    • Sivori, S.1    Vitale, M.2    Bottino, C.3    Marcenaro, E.4    Sanseverino, L.5    Parolini, S.6    Moretta, L.7    Moretta, A.8
  • 34
    • 0029057410 scopus 로고
    • Interaction between lck and syk family tyrosine kinases in Fcγ receptor-initiated activation of natural killer cells
    • Ting, A. T., C. J. Dick, R. A. Schoon, L. M. Karnitz, R. T. Abraham, and P. J. Leibson. 1995. Interaction between lck and syk family tyrosine kinases in Fcγ receptor-initiated activation of natural killer cells. J. Biol. Chem. 270:16415.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16415
    • Ting, A.T.1    Dick, C.J.2    Schoon, R.A.3    Karnitz, L.M.4    Abraham, R.T.5    Leibson, P.J.6
  • 35
    • 2642611958 scopus 로고    scopus 로고
    • Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: Association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases
    • Le Drean, E., F. Vely, L. Olcese, A. Cambiaggi, S. Guia, G. Krystal, N. Gervois, A. Moretta, F. Jotereau, and E. Vivier. 1998. Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases. Eur. J. Immunol. 28:264.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 264
    • Le Drean, E.1    Vely, F.2    Olcese, L.3    Cambiaggi, A.4    Guia, S.5    Krystal, G.6    Gervois, N.7    Moretta, A.8    Jotereau, F.9    Vivier, E.10
  • 36
    • 0028072499 scopus 로고
    • Inhibition of mast cell Fc∈RI-mediated signaling and effector function by the syk-selective inhibitor, piceatannol
    • Oliver, J. M., D. L. Burg, B. S. Wilson, J. L. McLaughlin, and R. L. Geahlen. 1994. Inhibition of mast cell Fc∈RI-mediated signaling and effector function by the syk-selective inhibitor, piceatannol. J. Biol. Chem. 269:29697.
    • (1994) J. Biol. Chem. , vol.269 , pp. 29697
    • Oliver, J.M.1    Burg, D.L.2    Wilson, B.S.3    McLaughlin, J.L.4    Geahlen, R.L.5
  • 37
    • 0027315182 scopus 로고
    • T cell antigen receptor signal transduction: A tale of tails and cytoplasmic protein-tyrosine kinases
    • Weiss, A. 1993. T cell antigen receptor signal transduction: a tale of tails and cytoplasmic protein-tyrosine kinases. Cell 73:209.
    • (1993) Cell , vol.73 , pp. 209
    • Weiss, A.1
  • 38
    • 0031572521 scopus 로고    scopus 로고
    • Selective binding of shc-SH2 domain to tyrosine-phosphorylated ζ-but not γ-chain upon CD16 ligation on human NK cells
    • Galandrini, R., G. Palmieri, R. Paolini, M. Piccoli, L. Frati, and A. Santoni. 1997. Selective binding of shc-SH2 domain to tyrosine-phosphorylated ζ-but not γ-chain upon CD16 ligation on human NK cells. J. Immunol. 159:3767.
    • (1997) J. Immunol. , vol.159 , pp. 3767
    • Galandrini, R.1    Palmieri, G.2    Paolini, R.3    Piccoli, M.4    Frati, L.5    Santoni, A.6
  • 39
    • 0029788070 scopus 로고    scopus 로고
    • FcγR-dependent mitogen-activated protein kinase activation in leukocytes: A common signal transduction event necessary for expression of TNF-α and early activation genes
    • Trotta, R., P. Kanakaraj, and B. Perussia. 1996. FcγR-dependent mitogen-activated protein kinase activation in leukocytes: a common signal transduction event necessary for expression of TNF-α and early activation genes. J. Exp. Med. 184:1027.
    • (1996) J. Exp. Med. , vol.184 , pp. 1027
    • Trotta, R.1    Kanakaraj, P.2    Perussia, B.3
  • 40
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger, R., and E. G. Krebs. 1995. The MAPK signaling cascade. FASEB J. 9:726.
    • (1995) FASEB J. , vol.9 , pp. 726
    • Seger, R.1    Krebs, E.G.2
  • 41
    • 0029671267 scopus 로고    scopus 로고
    • ras activation is associated with Shc and p36 tyrosine phosphorylation and their binding with Grb2 in human natural killer cells
    • ras activation is associated with Shc and p36 tyrosine phosphorylation and their binding with Grb2 in human natural killer cells. J. Exp. Med. 183:179.
    • (1996) J. Exp. Med. , vol.183 , pp. 179
    • Galandrini, R.1    Palmieri, G.2    Piccoli, M.3    Frati, L.4    Santoni, A.5
  • 42
    • 0030610802 scopus 로고    scopus 로고
    • Shc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIP
    • Lamkin, T. D., S. F. Walk, L. Liu, J. E. Damen, G. Krystal, and K. S. Ravichandran. 1997. Shc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIP. J. Biol. Chem. 272:10396.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10396
    • Lamkin, T.D.1    Walk, S.F.2    Liu, L.3    Damen, J.E.4    Krystal, G.5    Ravichandran, K.S.6
  • 43
    • 0031225997 scopus 로고    scopus 로고
    • Conservation of structural features reveals the existence of a large family of inhibitory cell surface receptors and noninhibitory/ activatory counterparts
    • Vely, F., and E. Vivier. 1997. Conservation of structural features reveals the existence of a large family of inhibitory cell surface receptors and noninhibitory/ activatory counterparts. J. Immunol. 159:2075.
    • (1997) J. Immunol. , vol.159 , pp. 2075
    • Vely, F.1    Vivier, E.2
  • 46
    • 0032006398 scopus 로고    scopus 로고
    • NK cell granule exocytosis and cytokine production inhibited by Ly-49A engagement
    • Kim, S., and W. M. Yokoyama. 1998. NK cell granule exocytosis and cytokine production inhibited by Ly-49A engagement. Cell. Immunol. 183:106.
    • (1998) Cell. Immunol. , vol.183 , pp. 106
    • Kim, S.1    Yokoyama, W.M.2
  • 47
    • 0029787216 scopus 로고    scopus 로고
    • Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase
    • Pani, G., K.-D. Fischer, I. Mlinaric-Rascan, and K. A. Siminovitch. 1996. Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase. J. Exp. Med. 184:839.
    • (1996) J. Exp. Med. , vol.184 , pp. 839
    • Pani, G.1    Fischer, K.-D.2    Mlinaric-Rascan, I.3    Siminovitch, K.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.