Differential roles of N- and C-terminal immunoreceptor tyrosine-based inhibition motifs during inhibition of cell activation by killer cell inhibitory receptors

Journal of Immunology

Volumn 162, Issue 6, 1999, Pages 3168-3175

  Bruhns, Pierre ^a   Marchetti, Philippe ^a   Fridman, Wolf H ^a   Vivier, Eric ^b   Daëron, Marc ^a  

^a INSTITUT CURIE   (France)

^b Ctr d'Immunol Inst Natl S R   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; IMMUNOGLOBULIN E RECEPTOR; KILLER CELL INHIBITORY RECEPTOR; LYMPHOCYTE RECEPTOR; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIGEN RECOGNITION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEDIATED CYTOTOXICITY; CHIMERA; LYMPHOCYTE ACTIVATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; SEQUENCE HOMOLOGY;

ANIMALS; CELL LINE; IMMUNOSUPPRESSIVE AGENTS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MICE; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; RATS; RECEPTOR AGGREGATION; RECEPTORS, ANTIGEN, B-CELL; RECEPTORS, IGE; RECEPTORS, IMMUNOLOGIC; RECOMBINANT FUSION PROTEINS; SHP1 PROTEIN TYROSINE PHOSPHATASE; SRC HOMOLOGY DOMAINS; TUMOR CELLS, CULTURED; TYROSINE;

EID: 0033559899     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Moretta, A., R. Biassoni, C. Bottino, D. Pende, M. Vitale, A. Poggi, M. C. Mingari, and L. Moretta. 1997. Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes. Immunol. Rev. 155:105.
2. Long, E. O., D. N. Burshtyn, W. P. Clark, M. Peruzzi, S. Rajagopalan, S. Rojo, N. Wagtmann, and C. C. Winter. 1997. Killer cell inhibitory receptors: diversity, specificity, and function. Immunol. Rev. 155:135.
3. Lanier, L. L., B. Corliss, and J. H. Phillips. 1997. Arousal and inhibition of human NK cells. Immunol. Rev. 155:145.
4. Renard, V., A. Cambiaggi, F. Vely, M. Bléry, L. Olcese, S. Olivero, M. Bouchet, and E. Vivier. 1997 Transduction of cytotoxic signals in natural killer cells: a general model of fine tuning between activatory and inhibitory pathways in lymphocytes. Immunol. Rev. 155:205.
5. Ono, M., H. Okada, S. Bolland, S. Yanagi, T. Kurosaki, and J. V. Ravetch. 1997. Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling. Cell 90:293.
6. Bléry, M., J. Delon, A. Trautmann, A. Cambiaggi, L. Olcese, R. Biassoni, L. Moretta, P. Chavrier, A. Moretta, M. Daëron, and E. Vivier. 1997. Reconstituted killer-cell inhibitory receptors for MHC class I molecules control mast cell activation induced via immunoreceptor tyrosine-based activation motifs. J. Biol. Chem. 272:8989.
7. Vivier, E., and M. Daëron. 1997. Immunoreceptor tyrosine-based inhibition motifs. Immunol. Today 18:286.
8. Colonna, M., and J. Samaridis. 1995. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science 268:405.
9. Kaufman, D. S., R. A. Schoon, M. J. Robertson, and P. J. Leibson. 1995. Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I. Proc. Natl. Acad. Sci. USA 92:6484.
10. Amigorena, S., C. Bonnerot, J. Drake, D. Choquet, W. Hunziker, J. G. Guillet, P. Webster, C. Sautès, I. Mellman, and W. H. Fridman. 1992. Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B-lymphocytes. Science 256:1808.
11. Muta, T., T. Kurosaki, Z. Misulovin, M. Sanchez, M. C. Nussenzweig, and J. V. Ravetch. 1994. A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling. Nature 368:70.
12. Daëron, M., S. Latour, O. Malbec, E. Espinosa, P. Pina, S. Pasmans, and W. H. Fridman. 1995. The same tyrosine-based inhibition motif, in the intracytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation. Immunity 3:635.
13. Nakamura, M. C., E. C. Niemi, M. J. Fisher, L. D. Shultz, W. E. Seaman, and J. C. Ryan. 1997. Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase. J. Exp. Med. 185:673.
14. Le Drean, E., F. Vely, L. Olcese, A. Cambiaggi, S. Guia, G. Krystal, N. Gervois, A. Moretta, F. Jotereau, and E. Vivier. 1998. Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases. [Published erratum appears in 1998 Eur. J. Immunol. 28:1122]. Eur. J. Immunol. 28:264.
15. Campbell, M.-A., and N. R. Klinman. 1995. Phosphotyrosine-dependent association between CD22 and protein tyrosine phosphatase 1C. Eur. J. Immunol. 25: 1573.
16. Adachi, T., H. Flaswinkel, H. Yakura, M. Reth, and T. Tsubata. 1998. The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation. J. Immunol. 160:4662.
17. Wu, Y., M. J. S. Nadler, L. A. Brennan, G. D. Gish, J. F. Timms, N. Fusaki, J. Jongstra-Bilen, N. Tada, T. Pawson, J. Wither, B. G. Neel, and N. Hozumi. 1998. The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1. Curr. Biol. 8:1009.
18. Kubagawa, H., P. D. Burrows, and M. D. Cooper. 1997. A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells. Proc. Natl. Acad. Sci. USA 94:5261.
19. Katz, H. R., E. Vivier, M. C. Castells, M. J. McCormick, J. M. Chambers, and K. F. Austen. 1996. Mouse mast cell gp49B1 contains two immunoreceptor tyrosine-based inhibition motifs and suppresses mast cell activation upon coligation with FcεRI. Proc. Natl. Acad. Sci. USA 93:10809.
20. Guthmann, M. D., M. Tal, and I. Pecht. 1995. A secretion inhibitory signal transduction molecule on mast cells is another C-type lectin. Proc. Natl. Acad. Sci. USA 92:9397.
21. Cella, M., C. Döhring, J. Samaridis, M. Dessing, M. Brockhaus, A. Lanzavecchia, and M. Colonna. 1997. A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing. J. Exp. Med. 185: 1743.
22. Colonna, M. 1997. Immunoglobulin-superfamily inhibitory receptors: from natural killer cells to antigen-presenting cells. Immunol. Res. 148:168.
23. Cosman, D., N. Fanger, L. Borges, M. Kubin, W. Chin, L. Peterson, and M. L. Hsu. 1997. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity 7:273.
24. Meyaard, L., G. Adema, C. Chang, E. Woollatt, G. R. Sutherland, L. L. Lanier, and J. H. Phillips. 1997. LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes. Immunity 7:283.
25. Fujioka, Y., T. Matozaki, T. Noguchi, A. Iwamatsu, T. Yamao, N. Takahashi, M. Tsuda, T. Takada, and M. Kasuga. 1996. A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion. Mol. Cell. Biol. 16:6887.
26. Kharitonenkov, A., Z. Chen, I. Sures, H. Wang, J. Schilling, and A. Ullrich. 1997. A family of proteins that inhibit signalling through tyrosine kinase receptors. Nature 386:181.
27. Burshtyn, D. N., W. Yang, T. Yi, and E. O. Long. 1997. A novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP-1. J. Biol. Chem. 272:13066.
28. Vély, F., S. Olivero, L. Olcese, A. Moretta, J. E. Damen, L. Liu, G. Krystal, J. C. Cambier, M. Daëron, and E. Vivier. 1997. Differential association of phosphatases with hematopoietic coreceptors bearing immunoreceptor tyrosine-based inhibition motifs. Eur. J. Immunol. 27:1994.
29. Olcese, L., P. Lang, F. Vély, A. Cambiaggi, D. Marguet, M. Bléry, K. L. Hippen, R. Biassoni, A. Moretta, L. Moretta, J. C. Cambier, and E. Vivier. 1996. Human and mouse killer cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases. J. Immunol. 156:4531.
30. Ono, M., S. Bolland, P. Tempst, and J. V. Ravetch. 1996. Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcγRIIB. Nature 383:263.
31. Fong, D. C., O. Malbec, M. Arock, J. C. Cambier, W. H. Fridman, and M. Daëron. 1996. Selective in vivo recruitment of the phosphatidylinositol phosphatase SHIP by phosphorylated FcγRIIB during negative regulation of IgE-dependent mouse mast cell activation. Immunol. Lett. 54:83.
32. Burshtyn, D. N., A. M. Scharenberg, N. Wagtmann, S. Rajagopalan, K. Berrada, T. Yi, J.-P. Kinet, and E. O. Long. 1996. Recruitment of tyrosine phosphatase HCP by the killer cell inhibitory receptor. Immunity 4:77.
33. Campbell, K. S., M. Dessing, M. Lopez-Botet, M. Cella, and M. Colonna. 1996. Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C. J. Exp. Med. 184:93.
34. Fry, A. M., L. L. Lanier, and A. Weiss. 1996. Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C. J. Exp. Med. 184:295.
35. Eck, M. J., S. Pluskey, T. Trub, S. C. Harrison, and S. E. Shoelson. 1996. Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2. Nature 379:277.
36. Hof, P., S. Pluskey, S. Dhe-Paganon, M. J. Eck, and S. E. Shoelson. 1998. Crystal structure of the tyrosine phosphatase SHP-2. Cell 92:441.
37. Barsumian, E. L., C. Isersky, M. G. Petrino, and R. P. Siraganian. 1981. IgE-induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones. Eur. J. Immunol. 11:317.
38. Bonnerot, C., M. Daëron, N. Varin, S. Amigorena, P. M. Hogarth, J. Even, and W. H. Fridman. 1988. Methylation in the 5′ region of the murine β FcγR gene regulates the expression of Fcγ receptor II. J. Immunol. 141:1026.
39. Jones, B., J. P. Tite, and C. A. Janeway, Jr. 1986. Different phenotypic variants of the mouse B cell tumor A20/2J are selected by antigen- and mitogen-triggered cytotoxicity of L3T4-positive, I-A-restricted T cell clones. J. Immunol. 136:348.
40. Liu, T. T., J. W. Bohn, E. L. Ferry, H. Yamamoto, and C. A. Molinaro. 1980. Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterization. J. Immunol. 124:2728.
41. Unkeless, J. C. 1979. Characterization of monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. J. Exp. Med. 150:580.
42. Takebe, Y., M. Seiki, J. I. Fujisawa, P. Hoy, K. Yokota, K. I. Arai, M. Yoshida, and N. Arai. 1988. SRα promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Mol. Cell. Biol. 8:466.
43. Wagtmann, N., R. Biassoni, C. Cantoni, S. Verdiani, M. S. Malnati, M. Vitale, C. Bottino, L. Moretta, A. Moretta, and E. Long. 1995. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity 2:439.
44. Daëron, M., C. Bonnerot, S. Latour, and W. H. Fridman. 1992. Murine recombinant FcγRIII, but not FcγRII, trigger serotonin release in rat basophilic leukemia cells. J. Immunol. 149:1365.
45. Gillis, S., and K. Smith. 1977. Long-term culture of tumour-specific cytotoxic T-cells. Nature 268:154.
46. Hippen, K. L., A. M. Buhl, D. D'Ambrosio, K. Nakamura, C. Persin, and J. C. Cambier. 1997. FcγRIIB1 inhibition of BCR-mediated phosphoinositide hydrolysis and calcium mobilization is integrated by CD19 dephosphorylation. Immunity 7:49.
47. Malbec, O., D. Fong, M. Turner, V. L. J. Tybulewicz, J. C. Cambier, W. H. Fridman, and M. Daëron. 1998. FcεRI-associated lyn-dependent phosphorylation of FcγRIIB during negative regulation of mast cell activation. J. Immunol. 160:1647.
48. Binstadt, B. A., K. M. Brumbaugh, C. J. Dick, A. M. Scharenberg, B. L. Williams, M. Colonna, L. L. Lanier, J.-P. Kinet, R. T. Abraham, and P. J. Leibson. 1996. Sequential involvement of lck and SHP-1 with MHC-recognizing receptors on NK cells inhibits FcR-initiated tyrosine kinase activation. Immunity 5:629.
49. lck kinase. Eur. J. Immunol. 24:2527.
50. Feng, G. S., R. Shen, H. H. Heng, L. C. Tsui, A. Kazlauskas, and T. Pawson. 1994. Receptor-binding, tyrosine phosphorylation, and chromosome localization of the mouse SH2-conlaining phosphotyrosine phosphatase Syp. Oncogene 9:1545.
51. Symes, A., N. Stahl, S. A. Reeves, T. Farruggella, T. Servidei, T. Gearan, G. Yancopoulos, and J. S. Fink. 1997. The protein tyrosine phosphatase SHP-2 negatively regulates ciliary neurotrophic factor induction of gene expression. Curr. Biol. 7:697.
52. Nakamura, K., and J. C. Cambier. 1998. B cell antigen receptor (BCR)-mediated formation of a SHP-2-pp120 complex and its inhibition by FcgRIIB1-BCR coligation. J. Immunol. 161:684.
53. Gadina, M., L. M. Stancato, C. M. Bacon, A. C. Larner, and J. J. O'Shea. 1998. Involvement of SHP-2 in multiple aspects of IL-2 signaling: evidence for a positive regulatory role. J. Immunol. 160:4657.