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Volumn 451, Issue 1-2, 2000, Pages 227-240

DNA ends: Maintenance of chromosome termini versus repair of double strand breaks

Author keywords

ALT mechanism; DNA repair; Double strand breaks; Survivor pathway; Telomeres

Indexed keywords

DOUBLE STRANDED DNA;

EID: 0034733690     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(00)00052-X     Document Type: Review
Times cited : (69)

References (87)
  • 1
    • 0032483562 scopus 로고    scopus 로고
    • DNA damage and checkpoint pathways: Molecular anatomy and interactions with repair
    • Weinert T. DNA damage and checkpoint pathways: molecular anatomy and interactions with repair. Cell. 94:1998;555-558.
    • (1998) Cell , vol.94 , pp. 555-558
    • Weinert, T.1
  • 2
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • Paques F., Haber J.E. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 63:1999;349-404.
    • (1999) Microbiol. Mol. Biol. Rev. , vol.63 , pp. 349-404
    • Paques, F.1    Haber, J.E.2
  • 3
    • 0032574750 scopus 로고    scopus 로고
    • Homology-directed repair is a major double-strand break repair pathway in mammalian cells
    • Liang F., Han M., Romanienko P.J., Jasin M. Homology-directed repair is a major double-strand break repair pathway in mammalian cells. Proc. Natl. Acad. Sci. U. S. A. 95:1998;5172-5177.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 5172-5177
    • Liang, F.1    Han, M.2    Romanienko, P.J.3    Jasin, M.4
  • 5
    • 0025201982 scopus 로고
    • Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription
    • Gottschling D.E., Aparicio O.M., Billington B.L., Zakian V.A. Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell. 63:1990;751-762.
    • (1990) Cell , vol.63 , pp. 751-762
    • Gottschling, D.E.1    Aparicio, O.M.2    Billington, B.L.3    Zakian, V.A.4
  • 6
    • 0033522444 scopus 로고    scopus 로고
    • Limitations of silencing at native yeast telomeres
    • Pryde F.E., Louis E.J. Limitations of silencing at native yeast telomeres. EMBO J. 18:1999;2538-2550.
    • (1999) EMBO J. , vol.18 , pp. 2538-2550
    • Pryde, F.E.1    Louis, E.J.2
  • 7
    • 0032055730 scopus 로고    scopus 로고
    • Mechanisms of silencing in Saccharomyces cerevisiae
    • Lustig A.J. Mechanisms of silencing in Saccharomyces cerevisiae. Curr. Opin. Genet. Dev. 8:1998;233-239.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 233-239
    • Lustig, A.J.1
  • 8
    • 0030931491 scopus 로고    scopus 로고
    • Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
    • Blasco M., Lee H., Hande M., Samper E., Lansdorp P., DePinho R., Greider C. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell. 91:1997;25-34.
    • (1997) Cell , vol.91 , pp. 25-34
    • Blasco, M.1    Lee, H.2    Hande, M.3    Samper, E.4    Lansdorp, P.5    Depinho, R.6    Greider, C.7
  • 9
    • 3543142313 scopus 로고    scopus 로고
    • Two modes of survival of fission yeast without telomerase
    • Nakamura T.M., Cooper J.P., Cech T.R. Two modes of survival of fission yeast without telomerase. Science. 282:1998;493-496.
    • (1998) Science , vol.282 , pp. 493-496
    • Nakamura, T.M.1    Cooper, J.P.2    Cech, T.R.3
  • 10
    • 0029845892 scopus 로고    scopus 로고
    • Cdc13p: A single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance
    • Nugent C.I., Hughes T.R., Lue N.F., Lundblad V. Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance. Science. 274:1996;249-252.
    • (1996) Science , vol.274 , pp. 249-252
    • Nugent, C.I.1    Hughes, T.R.2    Lue, N.F.3    Lundblad, V.4
  • 11
    • 0030447657 scopus 로고    scopus 로고
    • The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo
    • Lin J.J., Zakian V.A. The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo. Proc. Natl. Acad. Sci. U. S. A. 93:1996;13760-13765.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 13760-13765
    • Lin, J.J.1    Zakian, V.A.2
  • 12
    • 0028822203 scopus 로고
    • Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
    • Garvik B., Carson M., Hartwell L. Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol. Cell. Biol. 15:1995;6128-6138.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6128-6138
    • Garvik, B.1    Carson, M.2    Hartwell, L.3
  • 14
  • 15
    • 0029763191 scopus 로고    scopus 로고
    • Purification of telomerase from Euplotes aediculatus: Requirement of a primer 3′ overhang
    • Lingner J., Cech T.R. Purification of telomerase from Euplotes aediculatus: requirement of a primer 3′ overhang. Proc. Natl. Acad. Sci. U. S. A. 93:1996;10712-10717.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 10712-10717
    • Lingner, J.1    Cech, T.R.2
  • 16
    • 0031029001 scopus 로고    scopus 로고
    • Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13
    • Grandin N., Reed S.I., Charbonneau M. Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13. Genes Dev. 11:1997;512-527.
    • (1997) Genes Dev. , vol.11 , pp. 512-527
    • Grandin, N.1    Reed, S.I.2    Charbonneau, M.3
  • 17
    • 0030455861 scopus 로고    scopus 로고
    • Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes
    • Lendvay T.S., Morris D.K., Sah J., Balasubramanian B., Lundblad V. Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. Genetics. 144:1996;1399-1412.
    • (1996) Genetics , vol.144 , pp. 1399-1412
    • Lendvay, T.S.1    Morris, D.K.2    Sah, J.3    Balasubramanian, B.4    Lundblad, V.5
  • 18
    • 0030881688 scopus 로고    scopus 로고
    • Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity
    • Lingner J., Cech T.R., Hughes T.R., Lundblad V. Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity. Proc. Natl. Acad. Sci. U. S. A. 94:1997;11190-11195.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 11190-11195
    • Lingner, J.1    Cech, T.R.2    Hughes, T.R.3    Lundblad, V.4
  • 19
    • 0033214013 scopus 로고    scopus 로고
    • Est1 and Cdc13 as comediators of telomerase access
    • Evans S.K., Lundblad V. Est1 and Cdc13 as comediators of telomerase access. Science. 286:1999;117-120.
    • (1999) Science , vol.286 , pp. 117-120
    • Evans, S.K.1    Lundblad, V.2
  • 20
    • 0023037564 scopus 로고
    • Telomere proteins: Specific recognition and protection of the natural termini of Oxytricha macronuclear DNA
    • Gottschling D.E., Zakian V.A. Telomere proteins: specific recognition and protection of the natural termini of Oxytricha macronuclear DNA. Cell. 47:1986;195-205.
    • (1986) Cell , vol.47 , pp. 195-205
    • Gottschling, D.E.1    Zakian, V.A.2
  • 21
    • 0023433713 scopus 로고
    • Telomeric DNA-protein interactions of Oxytricha macronuclear DNA
    • Price C.M., Cech T.R. Telomeric DNA-protein interactions of Oxytricha macronuclear DNA. Genes Dev. 1:1987;783-793.
    • (1987) Genes Dev. , vol.1 , pp. 783-793
    • Price, C.M.1    Cech, T.R.2
  • 22
    • 0025345912 scopus 로고
    • Telomere structure in Euplotes crassus: Characterization of DNA-protein interactions and isolation of a telomere-binding protein
    • Price C.M. Telomere structure in Euplotes crassus: characterization of DNA-protein interactions and isolation of a telomere-binding protein. Mol. Cell. Biol. 10:1990;3421-3431.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 3421-3431
    • Price, C.M.1
  • 23
    • 0030982721 scopus 로고    scopus 로고
    • The terminal DNA structure of mammalian chromosomes
    • McElligott R., Wellinger R.J. The terminal DNA structure of mammalian chromosomes. EMBO J. 16:1997;3705-3714.
    • (1997) EMBO J. , vol.16 , pp. 3705-3714
    • McElligott, R.1    Wellinger, R.J.2
  • 25
    • 84984775429 scopus 로고    scopus 로고
    • Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2
    • Broccoli D., Smogorzewska A., Chong L., de Lange T. Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. Nat. Genet. 17:1997;231-235.
    • (1997) Nat. Genet. , vol.17 , pp. 231-235
    • Broccoli, D.1    Smogorzewska, A.2    Chong, L.3    De Lange, T.4
  • 26
    • 0031027618 scopus 로고    scopus 로고
    • Control of telomere length by the human telomeric protein TRF1
    • van Steensel B., de Lange T. Control of telomere length by the human telomeric protein TRF1. Nature. 385:1997;740-743.
    • (1997) Nature , vol.385 , pp. 740-743
    • Van Steensel, B.1    De Lange, T.2
  • 27
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • van Steensel B., Smogorzewska A., de Lange T. TRF2 protects human telomeres from end-to-end fusions. Cell. 92:1998;401-413.
    • (1998) Cell , vol.92 , pp. 401-413
    • Van Steensel, B.1    Smogorzewska, A.2    De Lange, T.3
  • 28
    • 0033605145 scopus 로고    scopus 로고
    • P53- And ATM-dependent apoptosis induced by telomeres lacking TRF2
    • Karlseder J., Broccoli D., Dai Y., Hardy S., de Lange T. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science. 283:1999;1321-1325.
    • (1999) Science , vol.283 , pp. 1321-1325
    • Karlseder, J.1    Broccoli, D.2    Dai, Y.3    Hardy, S.4    De Lange, T.5
  • 30
    • 0027263365 scopus 로고
    • Nuclear proteins that bind the pre-mRNA 3′ splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n
    • Ishikawa F., Matunis M.J., Dreyfuss G., Cech T.R. Nuclear proteins that bind the pre-mRNA 3′ splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n. Mol. Cell. Biol. 13:1993;4301-4310.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4301-4310
    • Ishikawa, F.1    Matunis, M.J.2    Dreyfuss, G.3    Cech, T.R.4
  • 31
    • 0031800617 scopus 로고    scopus 로고
    • Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase
    • LaBranche H., Dupuis S., Ben-David Y., Bani M.R., Wellinger R.J., Chabot B. Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase. Nat. Genet. 19:1998;199-202.
    • (1998) Nat. Genet. , vol.19 , pp. 199-202
    • Labranche, H.1    Dupuis, S.2    Ben-David, Y.3    Bani, M.R.4    Wellinger, R.J.5    Chabot, B.6
  • 32
    • 0032403147 scopus 로고    scopus 로고
    • Processing of telomeric DNA ends requires the passage of a replication fork
    • Dionne I., Wellinger R.J. Processing of telomeric DNA ends requires the passage of a replication fork. Nucleic Acids Res. 26:1998;5365-5371.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 5365-5371
    • Dionne, I.1    Wellinger, R.J.2
  • 33
    • 0030731928 scopus 로고    scopus 로고
    • Normal human chromosomes have long G-rich telomeric overhangs at one end
    • Wright W.E., Tesmer V.M., Huffman K.E., Levene S.D., Shay J.W. Normal human chromosomes have long G-rich telomeric overhangs at one end. Genes Dev. 11:1997;2801-2809.
    • (1997) Genes Dev. , vol.11 , pp. 2801-2809
    • Wright, W.E.1    Tesmer, V.M.2    Huffman, K.E.3    Levene, S.D.4    Shay, J.W.5
  • 34
    • 0032974345 scopus 로고    scopus 로고
    • Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27
    • Parenteau J., Wellinger R.J. Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27. Mol. Cell. Biol. 19:1999;4143-4152.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4143-4152
    • Parenteau, J.1    Wellinger, R.J.2
  • 35
    • 0033006852 scopus 로고    scopus 로고
    • Ku, a DNA repair protein with multiple cellular functions?
    • Featherstone C., Jackson S.P. Ku, a DNA repair protein with multiple cellular functions? Mutat. Res. 434:1999;3-15.
    • (1999) Mutat. Res. , vol.434 , pp. 3-15
    • Featherstone, C.1    Jackson, S.P.2
  • 36
    • 0032567041 scopus 로고    scopus 로고
    • The many interfaces of Mre11
    • Haber J.E. The many interfaces of Mre11. Cell. 95:1998;583-586.
    • (1998) Cell , vol.95 , pp. 583-586
    • Haber, J.E.1
  • 37
    • 0033603240 scopus 로고    scopus 로고
    • Sir-Ku-itous routes to make ends meet
    • Haber J.E. Sir-Ku-itous routes to make ends meet. Cell. 97:1999;829-832.
    • (1999) Cell , vol.97 , pp. 829-832
    • Haber, J.E.1
  • 38
    • 0032544276 scopus 로고    scopus 로고
    • Telomeres - unsticky ends
    • Shore D. Telomeres - unsticky ends. Science. 281:1998;1818-1819.
    • (1998) Science , vol.281 , pp. 1818-1819
    • Shore, D.1
  • 39
    • 0032052815 scopus 로고    scopus 로고
    • Interaction of Ku protein and DNA-dependent protein kinase subunits with nucleic acids
    • Dynan W.S., Yoo S. Interaction of Ku protein and DNA-dependent protein kinase subunits with nucleic acids. Nucleic Acids Res. 26:1998;1551-1559.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 1551-1559
    • Dynan, W.S.1    Yoo, S.2
  • 40
    • 0027971222 scopus 로고
    • An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae
    • Kato R., Ogawa H. An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae. Nucleic Acids Res. 22:1994;3104-3112.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 3104-3112
    • Kato, R.1    Ogawa, H.2
  • 41
    • 0028353634 scopus 로고
    • Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
    • Weinert T.A., Kiser G.L., Hartwell L.H. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev. 8:1994;652-665.
    • (1994) Genes Dev. , vol.8 , pp. 652-665
    • Weinert, T.A.1    Kiser, G.L.2    Hartwell, L.H.3
  • 42
    • 0029088371 scopus 로고
    • TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene
    • Greenwell P.W., Kronmal S.L., Porter S.E., Gassenhuber J., Obermaier B., Petes T.D. TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell. 82:1995;823-829.
    • (1995) Cell , vol.82 , pp. 823-829
    • Greenwell, P.W.1    Kronmal, S.L.2    Porter, S.E.3    Gassenhuber, J.4    Obermaier, B.5    Petes, T.D.6
  • 43
    • 0029150855 scopus 로고
    • TEL1, an S. cerevisiae, homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
    • Morrow D.M., Tagle D.A., Shiloh Y., Collins F.S., Hieter P. TEL1, an S. cerevisiae, homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell. 82:1995;831-840.
    • (1995) Cell , vol.82 , pp. 831-840
    • Morrow, D.M.1    Tagle, D.A.2    Shiloh, Y.3    Collins, F.S.4    Hieter, P.5
  • 44
    • 0033560796 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase
    • Smith G.C., Jackson S.P. The DNA-dependent protein kinase. Genes Dev. 13:1999;916-934.
    • (1999) Genes Dev. , vol.13 , pp. 916-934
    • Smith, G.C.1    Jackson, S.P.2
  • 45
    • 0029843408 scopus 로고    scopus 로고
    • Identification of a Saccharomyces cerevisiae Ku80 homologue: Roles in DNA double strand break rejoining and in telomeric maintenance
    • Boulton S.J., Jackson S.P. Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Res. 24:1996;4639-4648.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4639-4648
    • Boulton, S.J.1    Jackson, S.P.2
  • 46
    • 0029919650 scopus 로고    scopus 로고
    • The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae
    • Porter S.E., Greenwell P.W., Ritchie K.B., Petes T.D. The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae. Nucleic Acids Res. 24:1996;582-585.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 582-585
    • Porter, S.E.1    Greenwell, P.W.2    Ritchie, K.B.3    Petes, T.D.4
  • 48
    • 0032076127 scopus 로고    scopus 로고
    • Yeast Ku as a regulator of chromosomal DNA end structure
    • Gravel S., Larrivee M., Labrecque P., Wellinger R.J. Yeast Ku as a regulator of chromosomal DNA end structure. Science. 280:1998;741-745.
    • (1998) Science , vol.280 , pp. 741-745
    • Gravel, S.1    Larrivee, M.2    Labrecque, P.3    Wellinger, R.J.4
  • 49
    • 0032474732 scopus 로고    scopus 로고
    • The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities
    • Polotnianka R.M., Li J., Lustig A.J. The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities. Curr. Biol. 8:1998;831-834.
    • (1998) Curr. Biol. , vol.8 , pp. 831-834
    • Polotnianka, R.M.1    Li, J.2    Lustig, A.J.3
  • 50
    • 0032536861 scopus 로고    scopus 로고
    • Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
    • Boulton S.J., Jackson S.P. Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J. 17:1998;1819-1828.
    • (1998) EMBO J. , vol.17 , pp. 1819-1828
    • Boulton, S.J.1    Jackson, S.P.2
  • 52
    • 0030964526 scopus 로고    scopus 로고
    • Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae
    • Tsukamoto Y., Kato J., Ikeda H. Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae. Nature. 388:1997;900-903.
    • (1997) Nature , vol.388 , pp. 900-903
    • Tsukamoto, Y.1    Kato, J.2    Ikeda, H.3
  • 53
    • 0033612287 scopus 로고    scopus 로고
    • Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
    • Martin S.G., Laroche T., Suka N., Grunstein M., Gasser S.M. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell. 97:1999;621-633.
    • (1999) Cell , vol.97 , pp. 621-633
    • Martin, S.G.1    Laroche, T.2    Suka, N.3    Grunstein, M.4    Gasser, S.M.5
  • 54
    • 0033533699 scopus 로고    scopus 로고
    • Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins
    • Mishra K., Shore D. Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins. Curr. Biol. 9:1999;1123-1126.
    • (1999) Curr. Biol. , vol.9 , pp. 1123-1126
    • Mishra, K.1    Shore, D.2
  • 56
    • 0033597820 scopus 로고    scopus 로고
    • Ku binds telomeric DNA in vitro
    • Bianchi A., de Lange T. Ku binds telomeric DNA in vitro. J. Biol. Chem. 274:1999;21223-21227.
    • (1999) J. Biol. Chem. , vol.274 , pp. 21223-21227
    • Bianchi, A.1    De Lange, T.2
  • 57
    • 0033539095 scopus 로고    scopus 로고
    • DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of SIR3p
    • McAinsh A.D., Scott-Drew S., Murray J.A., Jackson S.P. DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of SIR3p. Curr. Biol. 9:1999;963-966.
    • (1999) Curr. Biol. , vol.9 , pp. 963-966
    • McAinsh, A.D.1    Scott-Drew, S.2    Murray, J.A.3    Jackson, S.P.4
  • 58
    • 0033612189 scopus 로고    scopus 로고
    • MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks
    • Mills K.D., Sinclair D.A., Guarente L. MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. Cell. 97:1999;609-620.
    • (1999) Cell , vol.97 , pp. 609-620
    • Mills, K.D.1    Sinclair, D.A.2    Guarente, L.3
  • 59
    • 0033565609 scopus 로고    scopus 로고
    • Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths
    • Lee S.E., Sylvan P.q.F.J., Haber J.E. Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths. Curr. Biol. 9:1999;767-770.
    • (1999) Curr. Biol. , vol.9 , pp. 767-770
    • Lee, S.E.1    Sylvan, P.q.F.J.2    Haber, J.E.3
  • 60
    • 0030849085 scopus 로고    scopus 로고
    • Identification of Saccharomyces cerevisiae DNA ligase IV: Involvement in DNA double-strand break repair
    • Teo S.H., Jackson S.P. Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair. EMBO J. 16:1997;4788-4795.
    • (1997) EMBO J. , vol.16 , pp. 4788-4795
    • Teo, S.H.1    Jackson, S.P.2
  • 61
    • 0032528066 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae LIF1: A function involved in DNA double-strand break repair related to mammalian XRCC4
    • Herrmann G., Lindahl T., Schar P. Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4. EMBO J. 17:1998;4188-4198.
    • (1998) EMBO J. , vol.17 , pp. 4188-4198
    • Herrmann, G.1    Lindahl, T.2    Schar, P.3
  • 62
    • 0028260976 scopus 로고
    • Overcoming telomeric silencing: A trans-activator competes to establish gene expression in a cell cycle-dependent way
    • Aparicio O.M., Gottschling D.E. Overcoming telomeric silencing: a trans-activator competes to establish gene expression in a cell cycle-dependent way. Genes Dev. 8:1994;1133-1146.
    • (1994) Genes Dev. , vol.8 , pp. 1133-1146
    • Aparicio, O.M.1    Gottschling, D.E.2
  • 63
    • 0000393532 scopus 로고
    • Identification of yeast mutants with altered telomere structure
    • Lustig A., Petes T.D. Identification of yeast mutants with altered telomere structure. Proc. Natl. Acad. Sci. U. S. A. 83:1986;1398-1402.
    • (1986) Proc. Natl. Acad. Sci. U. S. A. , vol.83 , pp. 1398-1402
    • Lustig, A.1    Petes, T.D.2
  • 64
    • 0032793298 scopus 로고    scopus 로고
    • Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae
    • Ritchie K.B., Mallory J.C., Petes T.D. Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 19:1999;6065-6075.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 6065-6075
    • Ritchie, K.B.1    Mallory, J.C.2    Petes, T.D.3
  • 65
    • 0032085295 scopus 로고    scopus 로고
    • The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks
    • Paull T.T., Gellert M. The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks. Mol. Cell. 1:1998;969-979.
    • (1998) Mol. Cell , vol.1 , pp. 969-979
    • Paull, T.T.1    Gellert, M.2
  • 66
    • 0032931844 scopus 로고    scopus 로고
    • The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance
    • Moreau S., Ferguson J.R., Symington L.S. The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol. Cell. Biol. 19:1999;556-566.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 556-566
    • Moreau, S.1    Ferguson, J.R.2    Symington, L.S.3
  • 67
    • 0028212415 scopus 로고
    • Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae
    • Ivanov E.L., Sugawara N., White C.I., Fabre F., Haber J.E. Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae. Mol. Cell. Biol. 14:1994;3414-3425.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3414-3425
    • Ivanov, E.L.1    Sugawara, N.2    White, C.I.3    Fabre, F.4    Haber, J.E.5
  • 68
    • 0032493889 scopus 로고    scopus 로고
    • Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage
    • Lee S.E., Moore J.K., Holmes A., Umezu K., Kolodner R.D., Haber J.E. Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell. 94:1998;399-409.
    • (1998) Cell , vol.94 , pp. 399-409
    • Lee, S.E.1    Moore, J.K.2    Holmes, A.3    Umezu, K.4    Kolodner, R.D.5    Haber, J.E.6
  • 69
    • 0031983191 scopus 로고    scopus 로고
    • A novel mre11 mutation impairs processing of double-strand breaks of DNA during both mitosis and meiosis
    • Tsubouchi H., Ogawa H. A novel mre11 mutation impairs processing of double-strand breaks of DNA during both mitosis and meiosis. Mol. Cell. Biol. 18:1998;260-268.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 260-268
    • Tsubouchi, H.1    Ogawa, H.2
  • 70
    • 0021715715 scopus 로고
    • Transfer of yeast telomeres to linear plasmids by recombination
    • Dunn B., Szauter P., Pardue M.L., Szostak J.W. Transfer of yeast telomeres to linear plasmids by recombination. Cell. 39:1984;191-201.
    • (1984) Cell , vol.39 , pp. 191-201
    • Dunn, B.1    Szauter, P.2    Pardue, M.L.3    Szostak, J.W.4
  • 71
    • 0021381306 scopus 로고
    • Healing of broken linear dicentric chromosomes in yeast
    • Haber J.E., Thorburn P.C. Healing of broken linear dicentric chromosomes in yeast. Genetics. 106:1984;207-226.
    • (1984) Genetics , vol.106 , pp. 207-226
    • Haber, J.E.1    Thorburn, P.C.2
  • 73
    • 0024276515 scopus 로고
    • Large deletions result from breakage and healing of P. falciparum chromosomes
    • Pologe L.G., Ravetch J.V. Large deletions result from breakage and healing of P. falciparum chromosomes. Cell. 55:1988;869-874.
    • (1988) Cell , vol.55 , pp. 869-874
    • Pologe, L.G.1    Ravetch, J.V.2
  • 76
    • 0024973811 scopus 로고
    • A mutant with a defect in telomere elongation leads to senescence in yeast
    • Lundblad V., Szostak J.W. A mutant with a defect in telomere elongation leads to senescence in yeast. Cell. 57:1989;633-643.
    • (1989) Cell , vol.57 , pp. 633-643
    • Lundblad, V.1    Szostak, J.W.2
  • 77
    • 0027944347 scopus 로고
    • TLC1: Template RNA component of Saccharomyces cerevisiae telomerase
    • Singer M.S., Gottschling D.E. TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science. 266:1994;404-409.
    • (1994) Science , vol.266 , pp. 404-409
    • Singer, M.S.1    Gottschling, D.E.2
  • 79
    • 0027421043 scopus 로고
    • Loss of a yeast telomere: Arrest, recovery, and chromosome loss
    • Sandell L.L., Zakian V.A. Loss of a yeast telomere: arrest, recovery, and chromosome loss. Cell. 75:1993;729-739.
    • (1993) Cell , vol.75 , pp. 729-739
    • Sandell, L.L.1    Zakian, V.A.2
  • 81
    • 0029746495 scopus 로고    scopus 로고
    • Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase
    • McEachern M.J., Blackburn E.H. Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase. Genes Dev. 10:1996;1822-1834.
    • (1996) Genes Dev. , vol.10 , pp. 1822-1834
    • McEachern, M.J.1    Blackburn, E.H.2
  • 82
    • 0033513079 scopus 로고    scopus 로고
    • Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae
    • Teng S.C., Zakian V.A. Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol. Cell. Biol. 19:1999;8083-8093.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 8083-8093
    • Teng, S.C.1    Zakian, V.A.2
  • 83
    • 0021684719 scopus 로고
    • Rearrangements of highly polymorphic regions near telomeres of Saccharomyces cerevisiae
    • Horowitz H., Thorburn P., Haber J.E. Rearrangements of highly polymorphic regions near telomeres of Saccharomyces cerevisiae. Mol. Cell. Biol. 4:1984;2509-2517.
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 2509-2517
    • Horowitz, H.1    Thorburn, P.2    Haber, J.E.3
  • 84
    • 0025240770 scopus 로고
    • Mitotic recombination among subtelomeric Y′ repeats in Saccharomyces cerevisiae
    • Louis E.J., Haber J.E. Mitotic recombination among subtelomeric Y′ repeats in Saccharomyces cerevisiae. Genetics. 124:1990;547-559.
    • (1990) Genetics , vol.124 , pp. 547-559
    • Louis, E.J.1    Haber, J.E.2
  • 85
    • 0029162563 scopus 로고
    • Telomere elongation in immortal human cells without detectable telomerase activity
    • Bryan T.M., Englezou A., Gupta J., Bacchetti S., Reddel R.R. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J. 14:1995;4240-4248.
    • (1995) EMBO J. , vol.14 , pp. 4240-4248
    • Bryan, T.M.1    Englezou, A.2    Gupta, J.3    Bacchetti, S.4    Reddel, R.R.5
  • 86
    • 0030697342 scopus 로고    scopus 로고
    • Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
    • Bryan T., Englezou A., Dalla-Pozza L., Dunham M., Reddel R. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat. Med. 3:1997;1271-1274.
    • (1997) Nat. Med. , vol.3 , pp. 1271-1274
    • Bryan, T.1    Englezou, A.2    Dalla-Pozza, L.3    Dunham, M.4    Reddel, R.5
  • 87
    • 0033598944 scopus 로고    scopus 로고
    • Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta
    • Diede S.J., Gottschling D.E. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell. 99:1999;723-733.
    • (1999) Cell , vol.99 , pp. 723-733
    • Diede, S.J.1    Gottschling, D.E.2


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