Differential chromosome behaviour in mammalian oocytes exposed to the tranquilizer diazepam in vitro

Mutagenesis

Volumn 16, Issue 5, 2001, Pages 407-417

  Sun, Fengyun ^a   Yin, Hang ^b   Eichenlaub Ritter, Ursula ^a  

^a BIELEFELD UNIVERSITY   (Germany)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DIAZEPAM; TRANQUILIZER;

ANAPHASE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOSOME; CELL CYCLE; CELL DIVISION; CELLULAR DISTRIBUTION; CHROMOSOME; CHROMOSOME 16; CHROMOSOME 8; CHROMOSOME SEGREGATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EXPOSURE; ERROR; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC PREDISPOSITION; GENOME; IMMUNOFLUORESCENCE; IN VITRO STUDY; MAMMAL; MEIOSIS; MITOSIS SPINDLE; MOLECULAR PROBE; MOUSE; NONDISJUNCTION; NONHUMAN; OOCYTE; OOCYTE DEVELOPMENT; PRIORITY JOURNAL; RANDOMIZATION; SOMATIC CELL; X CHROMOSOME;

EID: 0034820091     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/16.5.407     Document Type: Article

References (93)

1. Aneuploidy: A report of an ECETOC task force
2. Specific numerical chromosomal aberrations induced by Adriamycin. Environ
3. Diazepam induces mitotic arrest at prometaphase by inhibiting centriolar separation
4. Chromosome anomalies in human oocytes in relation to age
5. Preimplantation genetic diagnosis of aneuploidy: Were we looking at the wrong chromosomes?
6. Detection of aneuploidy in rodent and human sperm by multicolor FISH after chronic exposure to diazepam
7. Evaluation of thresholds for benomyl- and carbendazim-induced aneuploidy in cultured human lymphocytes using fluorescence in situ hybridization
8. Chemically induced aneuploidy: Investigations into chromosome specific effects in mitosis
9. Isolation and initial characterization of a large repeat sequence element specific to mouse chromosome 8
10. Kinetochore fibers are not involved in the formation of the first meiotic spindle in mouse oocytes, but control the exit from the first meiotic M phase
11. Drugs and the treatment of psychiatric disorders
12. Age-associated micronuclei containing centromeres and the X chromosome in lymphocytes of women
13. The X chromosome frequently lags behind in female lymphocyte anaphase
14. Characterization of the kinetochore binding domain of CENP-E reveals interaction with the kinetochore proteins CENP-F and hBUBR1
15. Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC
16. Kinetochore size variation in mammalian chromosomes: An image analysis study with evolutionary implications
17. Parental age-related aneuploidy in human germ cells and offspring: A story of past and present
18. Genetics of oocyte ageing
19. The determinants of non-disjunction and their possible relationship with oocyte ageing
20. Chloral hydrate induced spindle aberrations, metaphase I arrest and aneuploidy in mouse oocytes
21. Nocodazole sensitivity, age-related aneuploidy and alterations in the cell circle during maturation of mouse oocytes
22. In vitro maturation of mouse oocytes isolated from late, middle and preantral graafian follicles
23. Chromosome painting reveals specific patterns of chromosome occurrence in mitomycin C- and diethylstilboestrol-induced micronuclei
24. A mechanism of X chromosome aneuploidy in lymphocytes of aging women
25. Factors affecting the displacement of human chromosomes from the metaphase plate
26. Differences in the error mechanisms affecting sex and autosomal chromosomes in women of different ages within the reproductive age group
27. Aneuploidy and aging: Chromosome studies on a random sample of the population using G-banding
28. The spindle checkpoint: Two transitions, two pathways
29. Induction of hypoploidy and cell cycle delay by acrylamide in somatic and germinal cells of male mice
30. Preimplantation diagnosis for aneuploidies in patients undergoing in vitro fertilization with a poor prognosis: Identification of the categories for which it should be proposed
31. The incidence, origin and etiology of aneuploidy
32. Exclusion of specific human chromosomes into micronuclei by 5-azacytidine treatment of lymphocyte cultures
33. Sex-chromosome pairing and activity during mammalian meiosis
34. Sex chromosomes, micronuclei and aging in women
35. The parental origin of the missing or additional chromosome in 45, X and 47, XXX female
36. Mitotic stability of yeast chromosomes: A colony colour assay that measures nondisjunction and chromosome loss
37. Chiasma-based genetic map of the mouse X chromosome
38. The control of mammalian female meiosis and the factors that influence chromosome segregation
39. Immunofluorescence analysis of diazepam-induced mitotic apparatus anomalies and chromosome loss in Chinese hamster cells
40. The origin of numerical chromosome abnormalities
41. Klinefelter's syndrome: An analysis of the origin of the additional sex chromosome using molecular probes
42. Interpretation of the biological relevance of genotoxicity test results: The importance of thresholds
43. Characterization of susceptible chiasma configurations that increase the risk for maternal nondisjunction of chromosome 21
44. Chiasma frequency, distribution and interference maps of mouse autosomes
45. Mutagenic activity of diazepam evaluated by in vivo cytogenetic tests
46. Specific regulation of CENP-E and kinetochores during meiosis I/meiosis II transition in pig oocytes
47. Nonrandom segregation of the mouse univalent X chromosome. Evidence of spindle-mediated meiotic drive
48. Lack of checkpoint control at the metaphase/anaphase transition: A mechanism of meiotic nondisjunction in mammalian females
49. In vivo studies on chemically induced aneuploidy in mouse somatic and germinal cells
50. A reliable, noninvasive technique for spindle imaging and enucleation of mammalian oocytes
51. Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro
52. The origin of 47, XXY and 47, XXX aneuploidy: Heterogeneous mechanisms and role of aberrant recombination
53. Mechanisms of maternal aneuploidy: FISH analysis of oocytes and polar bodies in patients undergoing assisted conception
54. 1,2-Propanediol-induced premature centromere separation in mouse oocytes and aneuploidy in one-cell zygotes
55. Postovulatory ageing of mouse oocytes in vivo and premature centromere separation and aneuploidy
56. Comparison of the aneugenic activity of diazepam in mouse oocytes and other mammalian cells
57. Fluorescence in situ hybridisation with chromosome-specific centromeric probes: A sensitive method to detect aneuploidy
58. Chromosome identification in human oocytes and polar bodies by spectral karyotyping
59. The parental origin of the extra X chromosome in 47, XXX females
60. Detection of chromosome loss and gain induced by griseofulvin, estramustine and vanadate in binucleated lymphocytes using FISH analysis
61. Aneuploidy induction in mouse spermatocytes
62. Selection of the most common chromosome abnormalities in oocytes prior to ICSI
63. An overview of the results of testing of known or suspected aneugens using mammalian cells in vitro
64. Y chromosome aneuploidy, micronuclei, kinetochores and aging in men
65. The frequency of aneuploidy in cultured lymphocytes is correlated with age and gender but not with reproductive history
66. The detection and evaluation of aneugenic chemicals
67. Interindividual variations in susceptibility and sensitivity: Linking risk assessment and risk management
68. Stch maps to mouse chromosome 16, extending the conserved synteny with human chromosome 21
69. Aneuploidy in human lymphocytes: An extensive study of eight individuals of various ages
70. Relation of benzodiazepine use to the risk of selected cancers: Breast, large bowel, malignant melanoma, lung, endometrium, ovary, non-Hodgkin's lymphoma, testis, Hodgkin's disease, thyroid and liver
71. Detection of aneuploidy by multicolor FISH in mouse sperm after in vivo treatment with acrylamide, colchicine, diazepam or thiabendazole
72. Consequences of non-extrusion of the first polar body and control of the sequential segregation of homologues and chromatids in mammalian oocytes
73. Association between spindle assembly checkpoint expression and maternal age in human oocytes
74. Trichlorfon induces spindle disturbances in V79 cells and aneuploidy in male mouse germ cells
75. In vivo cytogenetic damage revealed by FISH analysis of micronuclei in uncultured human T lymphocytes
76. Accelerated telomere shortening in the human inactive X chromosome
77. ATP content of human oocytes and developmental potential and outcome after in-vitro fertilization and embryo transfer
78. Prevention of age-related aneuploidies by polar body testing of oocytes
79. Decondensation of pericentric heterochromatin alters the sequence of centromere separation in mouse cells
80. A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity
81. Chromosomal differences in susceptibility to meiotic aneuploidy
82. A comparison of two in vitro mammalian cell cytogenetic assays for the detection of mitotic aneuploidy using 10 known or suspected aneugens
83. Mad2 binding by phosphorylated kinetochores links error detection and checkpoint action in mitosis
84. Peripheral-type benzodiazepine receptor ligands and serum steroid hormones
85. Comprehensive chromosomal analysis of human preimplantation embryos using whole genome amplification and single cell comparative genomic hybridization
86. CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment
87. Chromosomal influence on meiotic spindle assembly: Abnormal meiosis I in female Mlh1 mutant mice
88. Induction of chromosome-specific aneuploidy and micronuclei in human lymphocytes by metabolites of 1,3-butadiene
89. CENP-E links bi-polar spindle microtubule attachment at kinetochores to the mitotic checkpoint
90. CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase
91. Diazepam induces meiotic delay, aneuploidy and predivision of homologues and chromatids in mammalian oocytes
92. Trichlorfon exposure, spindle aberrations and nondisjunction in mammalian oocytes
93. CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila