Trichlorfon induces spindle disturbances in V79 cells and aneuploidy in male mouse germ cells

Mutagenesis

Volumn 15, Issue 1, 2000, Pages 17-24

  Sun, F Y ^a,c   Schmid, T E ^a   Schmid, E ^b   Baumgartner, A ^a   Adler, I D ^a  

^a Institute of Developmental Genetics   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c QINGDAO UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

METRIFONATE; POISON;

ANEUPLOIDY; ANIMAL CELL; ARTICLE; CELL DIVISION; CELL STRAIN V 79; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISOMY; DOSE RESPONSE; EPIDIDYMIS; FLUORESCENCE IN SITU HYBRIDIZATION; GERM CELL; MALE; MEIOSIS; MITOSIS INDEX; MITOSIS SPINDLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPERM;

ANIMALIA;

EID: 0033968380     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/15.1.17     Document Type: Article

References (89)

1. Adler, I.-D. (1993) Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study. Mutat. Res., 287, 131-137.
2. Adler, I.-D., Zhou, R. and Schmid, E. (1993) Perturbation of cell division by acrylamide in vitro and in vivo. Mutat. Res., 301, 249-254.
3. Adler, I.-D., Bishop, J., Lowe, X., Schmid, T.E., Schriever-Schwemmer, G., Wang, X. and Wyrobek, A.J. (1996) Spontaneous rates of chromosomal aneuploidies in sperm and offspring of mice: a validation of the detection of aneuploid sperm by fluorescence in situ hybridisation. Mutat. Res., 372, 259-268.
4. Andersen, O. and Ronne, M. (1983) Quantitation of spindle-inhibiting effects of metal compounds by chromosome length measurement. Hereditas, 98, 215-218.
5. Aquilina, G., Benigni, R., Bignami, M., Calcagnile, A., Dogliotti, E., Falcone, E. and Carere, A. (1984) Genotoxic activity of dichlorvos, trichlorfon and dichloroacetaldehyde. Pestic. Sci., 15, 439-442.
6. Bao, T. van, Szabo, I., Ruzicska, P. and Czeizel, A.E. (1974) Chromosome aberrations in patients suffering acute organic phosphate insecticide intoxication. Humangenetik, 24, 33-57.
7. Barrueco, C., Herrera, A. and de la Peña, E. (1991) Mutagenic evaluation of trichlorfon using different assay methods with Salmonella typhimurium. Mutagenesis, 6, 71-76.
8. Becker, K. and Schöneich, J. (1980) Dominant lethal test with trichlorfon in male mice. Mutat. Res., 74, 224.
9. Benigni, R., Bignami, M., Carer, A., Gogliotti, E., Novelleto, A. and Principe, R. (1980) Comparative mutational studies with diclorvos, trichlorfon and dichloroacetaldehyde. Toxicol. Lett., 1, 250.
10. Berge, G.N. and Nafstad, I. (1986) Distribution and placental transfer of trichlorfon in guinea pigs. Arch. Toxicol., 59, 26-29.
11. Bishop, C.E. and Hatat, D. (1987) Molecular cloning and sequence analysis of a mouse Y chromosome RNA transcript expressed in the testis. Nucleic Acids Res., 15, 2959-2969.
12. Bond, D.J. (1987) Mechanisms of aneuploid induction. Mutat. Res., 181, 257-266.
13. Boveri, T. (1914) Zur Frage der Entstehung maligner Tumoren. Fisher, Jena, Germany.
14. Boyle, A.L. and Ward, D. (1992) Isolation and initial characterization of a large repeat sequence element specific to mouse chromosome 8. Genomics, 12, 517-525.
15. Carere, A., Ortali, V.A., Cardamone, G., Torraca, A.M. and Raschetti, R. (1978) Mutagenicity of dichlorvos and other structurally related pesticides in Salmonella and Streptomyces. Chem. Biol. Intereact., 22, 297-308.
16. Chen, H.H., Hsueh, J.L., Sirianni, S.R. and Huang, C.C. (1981) Induction of sister chromatid exchanges and cell cycle delay in cultured mammalian cells treated with eight organophosphorus pesticides. Mutat. Res., 88, 307-316.
17. Chevret, E., Rousseaus, S., Monteil, M., Pelletier, R., Cozzi, J. and Sèle, B. (1995) Meiotic segregation of X and Y chromosomes and chromosome 1 analyzed by three-color FISH in human interphase spermatozoa. Cytogenet. Cell Genet., 71, 126-130.
18. Courtney, K.D., Andrews, J.E. and Springer, J. (1986) Assessment of teratogenic potential of trichlorfon in mice and rats. J. Environ. Sci. Health, B21, 207-227.
19. Czeizel, A.E. (1994) Phenotypic and cytogenetic studies in self-poisoned patients. Mutat. Res., 313, 175-181.
20. Czeizel, A.E., Elek, C., Gundy, S., Métneki, L., Nemes, E., Reis, A., Sperling, K., Tímár, L., Tusnády, G. and Virágh, Z. (1993) Environmental trichlorfon and cluster of congenital abnormalities. Lancet, 341, 539-542.
21. Dedek, W. (1981) Guanine N7 alkylation in mice in vivo by metrifonate: discussion of possible genotoxic risk in mammals. Acta Pharmacol Toxicol., 49 (suppl. V). 40-50.
22. Dedek, W., Scheufler, H. and Fisher, G.W. (1975) Mutagenicity of desmethyltrichlorfon in the dominant lethal test in mice. Arch. Toxicol., 33, 163-168.
23. Degraeve, N., Chollet, M.-C. and Moutschen, J. (1984) Cytogenetic and genetic effects of subchronic treatments with organophosphorus insecticides. Arch. Toxicol., 56, 66-67.
24. de Kergommeaux, D.J., Grant, W.F. and Sandhu, S.S. (1983) Clastogenic and physiological response of chromosomes to nine pesticides in the Vicia faba in vivo root tip assay system. Mutat. Res., 124, 69-84.
25. Disteche, C.M., Tantrvahi, U., Gandy, S., Eisenhard, M., Adler, D. and Kunkel, L.M. (1985) Isolation and characterization of two repetitve DNA fragments located near the centromere of the mouse X chromosome. Cytogenet. Cell Genet., 39, 262-268.
26. Doherty, A.T., Ellard, S., Parry, E.M. and Parry, J.M. (1996) A study of the aneugenic activity of trichlorfon detected by centromere-specific probes in human lymphoblastoid cell lines. Mutat. Res., 372, 221-231.
27. Galloway, S.M. (1994) Chromosome aberrations induced in vitro: mechanisms, delayed expression and intriguing questions. Environ. Mol. Mutagen., 23 (suppl. 24), 44-53.
28. Gilot-Delhalle, J., Colizzi, A., Moutschen, J. and Moutschen-Dahmen, M. (1983) Mutagenicity of some organophosphorus compounds at the ADE6 locus of Schizosacchammyces pombe. Mutat. Res., 117, 139-148.
29. Griffin, D.K., Abruzzo, M.A., Millie, E.A., Sheean, L.A., Feingold, E., Sherman, S.L. and Hassold, T.J. (1995) Non-disjunction in human sperm: evidence for an effect of increasing paternal age. Hum. Mol. Genet., 4, 2227-2232.
30. Hallak, M. and Giacobini, E. (1989) Physostibmine, tacrine and metrifonate: the effect of multiple doses on acetylcholine metabolism in rat brain. Neuropharmacology, 28, 199-206.
31. Herbold, B. (1979a) Micronucleus test on mouse to evaluate L 13/59 for potential mutagenic effects, unpublished report. Bayer AG, Wuppertal, Germany.
32. Herbold, B. (1979b) Dominant lethal study on male mouse to test for mutagenic effects, unpublished report. Bayer AG, Germany.
33. Ishidate, M. Jr. Sofuni, T. and Yoshikawa, K. (1981) Chromosomal aberration tests in vitro as a primary screening tool for environmental mutagens and/ or carcinogens. Gann, 27, 95-108.
34. Kurinniy, A.I. (1975) Comparative investigation of the cytogenetic effect of certain organophosphorus insecticides. Genetika, 11, 64-69.
35. Kurinniy, A.I. and Pilinskaya, M.A. (1977) Cytogenetic activity of the pesticides imidan, dipterex and gardona in cultured human lymphocytes. Genetika, 13, 337-339.
36. Kuzmenko, N.M., Didenko, G.G., Kurinniy, A.I., Martson, L.V., Petrovskaya, O.G., Pilinskaya, M.A. and Shepelskaya, N.R. (1980) Long term health effects of pesticides. Gig. Sanit., 45, 88-89.
37. Lebrun, A. and Cerf, C. (1960) Noté préliminaire sur la toxicité pour l'homme d'un insecticide organo-phosphoré (Dipterex). Bull. World Health Organ., 22, 579-582.
38. Logvinenko, V.F. and Morgun, V.V. (1978) Mutagenic effect of several pesticides on durum spring wheat. Tsitol. Genet., 12, 207-212.
39. Lorenz, W., Henglein, A. and Schrader, G. (1955) The new insecticide 0,0-dimethyl-2,2,2-trichloro-1-hydroxyethyal phosphonate. J. Am. Chem. Soc., 77, 2554-2556.
40. Lowe, X., Collins, B., Allen, J., Titenko-Holland, N., Brenemen, J., van Beek, M., Bishop, J. and Wyrobek, A.J. (1995) Aneuploidies and micronuclei in the germ cells of mice of advanced age. Mutat. Res., 338, 59-76.
41. Lowe, X., O'Hogan, S., Moor, D., Bishop, J. and Wyrobek, A.J. (1996) Aneuploid epididymal sperm detected in chromosomally normal and translocation-bearing mice using a new three-chromosome FISH method. Chromosoma, 105, 204-210.
42. Lowe, X.R., de Stoppelaar, J.M., Bishop, J., Cassel, M., Hoebee, B., Moor, D. and Wyrobek, A.J. (1998) Epididymal sperm aneuploidies in three strains of rats detected by multicolor fluorescence in situ hybridization. Environ. Mol. Mutagen., 31, 125-132.
43. Madrigal-Bujaidar, E., Reyes Cadena, S., Trujillo-Vaillés, V.M. and Cassani, M. (1993) Sister-chromalid exchange frequencies induced by metrifonate in mammalian in vivo and in vitro systems. Mutat. Res., 300, 135-140.
44. Malagón, F. (1989) Elementos del binomio taeniasis/cisticercosis. Una sintesis. In Flisser, A. and Malagón, F. (eds), Cisticercosis Humanay Porcina. Editorial Limusa, Mexico D.F., Mexico.
45. Martin, R.H., Rademaker, A. and Leonard, N.J. (1995) Analysis of chromosomal abnormalities in human sperm after chemotherapy by karyotyping and fluorescence in situ hybridization (FISH). Cancer Genet. Cvtogenet., 80, 29-32.
46. McGregor, D.B., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C. and Caspary, W.J. (1988) Responses of the L5178Y tk+/tk-mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Mol. Mutagen., 12, 85-154.
47. Metcalf, R.L, Fukuto, T.R. and Murch, R.B. (1959) Toxic action of Dipterex and DDVP to the house fly. J. Econ. Entomol., 52, 44-49.
48. Miyamoto, J. (1959) Non-enzymatic conversion of Dipterex into DDVP and their inhibitory action on enzymes. Botyu-Kagaku, 24, 130-137.
49. Morya, M., Ohta, T., Watanabe, K., Miyazawa, T., Kata, K. and Shirasu, Y. (1983) Further mutagenicity studies on pesticides in bacterial reversion assay systems. Mutat. Res., 116, 185-216.
50. Nehéz, M., Huszta,E., Mazzag, E., Scheufler, H., Schneider, P. and Fischer, G.W. (1987) Cytogenetic, genetic and embryotoxicity studies with dimethyl 2,2, 2-trichloro-1-(2,2,2-trichloro-1-hydroxyethoxy)-ethylphosphonate, a hypothetical impurity in technical grade trichlorfon. Ecotoxicol. Environ. Saf., 13, 216-224.
51. Nordgren, I., Bergström, M., Holmstedt, B. and Sandoz, M. (1978) Transformation and action of metrifonate. Arch. Toxicol., 41, 31-41.
52. Ostergren, G. (1944) Colchicine, mitosis, chromosome concentration, necrosis and protein chain folding. Hereditas, 30, 429-167.
53. Paik, S. and Lee, S. (1977) Genetic effects of pesticides in the mammalian cells. 1. Induction of micronucleus. Korean J. Zool., 20, 19-28.
54. Panda, B.B. and Sharma, C.B. (1980) Cytogenetic hazards from agricultural chemicals: 3. Monitoring the Cytogenetic activity of trichlorfon and dichlorvos in Hordeum vulgare. Mutat. Res., 78, 343-345.
55. Parry, E.M., Henderson, L. and Parry, .J.M. (1995) Procedures for the detection of chemically induced aneuploidy: recommendations of a UK Environmental Mutagen Society working group. Mutagenesis, 10, 1-14.
56. Pieters, M.H., Geraedts, J.R, Meyer, H., Dumoulin J.C., Evers, J.L., Jongbloed, R.J., Nederlof, P.M. and van der Flier, S. (1990) Human gametes and zygotes studied by non-radioactive in situ hybridization. Cytogenet. Cell Genet., 53, 15-19.
57. Pinkel, D., Straume, T. and Gray, J.W. (1986) Cytogenetic analysis using quantitive, high-sensitivity fluorescence hybridization. Proc. Natl Acad. Sci. USA, 83, 2934-2938.
58. Pinkel, D., Landegent, J., Collins, C., Fiscoe, J., Segraves, R., Lucas, J. and Gray, J. (1988) Fluorescence in situ hybridization with human chromosome specific libraries: detection of trisomy 21 and translocations of chromosome 4. Proc. Natl Acad Sci. USA. 85, 9138-9142.
59. Poole, D.C., Simmon, V.F. and Newell, G.W. (1977) In vitro mutagenic activity of fourteen pesticides. Toxicol. Appl. Pharmacol., 41, 196.
60. Reiner, E., Krauthacker, B., Simeon, V. and Skrinjaric-Spoluar, M. (1975) Mechanism of inhibition in vitro of mammalian acetyl-cholinesterase and cholinesterase in solutions of 0,0-dimethyl-2,2,2-trichloro-1-hydroxyethyl phosphonate (trichlorphon). Biochem. Pharmacol., 24, 717-722.
61. Rew, D.A. (1994) Significance of aneuploidy. Br. J. Surg., 81, 1416-1422.
62. Riccio, E., Shepherd, G., Pomeroy, A., Mortelmans, K. and Waters, M.D. (1981) Comparative studies between the 5. cerevisiae D3 and D7 assay of eleven pesticides. Environ. Mutagen., 3, 327 (abstract)
63. Robbins, W.A., Segraves, R., Pinkel, D. and Wyrobek, A.J. (1993a) Detection of aneuploid human sperm by fluorescence in situ hybridization: evidence for a donor difference in frequency of sperm disomic for chromosomes 1 and Y. Am. J. Hum. Genet., 52, 799-807.
64. Robbins, W.A., Baulch, J.E., Moore, D., Weier, H.U., Blakey, D. and Wyrobek, A.J. (1993b) Three-probe fluorescence in situ hybridization to assess chromosome X, Y, 8 aneuploidy in sperm of 14 men from two healthy populations. Am. J. Med. Genet., 53, 1-7.
65. Robbins, W.A., Baulch, J.E., Moore, D., Weier, H.U., Blakey, D. and Wyrobek. A.J. (1995) Three-probe fluorescence in situ hybridization to assess chromosome X, Y, 8 aneuploidy in sperm of 14 men from two healthy groups: evidence for a paternal age effect on sperm aneuploidy. Reprod. Fertil. Dev.. 4, 799-809.
66. Robbins, W.A., Meistrich, M.L., Moore, D., Hagemeister, F.B. Weier, H.U., Cassel, M.J., Wilson, G., Eskenazi, B. and Wyrobek, A.J. (1997) Chemotherapy induces transient sex chromosomal and autosomal aneuploidy in human sperm. Nature Genet., 16, 74-78.
67. Ryazanova, R.A. and Gafurova, T.V. (1980) Mutagenic action of a binary mixture of the pesticides chlorophos and zineb. Gig. Sanit., 1, 80-81.
68. Sasaki, M., Sugimura, K., Yoshida, M. and Abe, S. (1980) Cytogenetic effects of 60 chemicals on cultured human and Chinese hamster cells. Senshokutai, 20, 574-584.
69. Scarpato, R., Naccarati, A., Mariani, M. and Migliore, L. (1998) Aneuploidy and diploidy rates in sperm of five men after three-color hybridization: indication of X chromosome-associated autosome 2 aneuploidy. Mutat. Res., 412, 227-233.
70. Schmid, T.E., Wang, X. and Adler, I.-D. (1999) Detection of aneuploidy by multicolor FISH in mouse sperm after in vivo treatment with acrylamide, colchicine, diazepam or thiabendazole. Mutagenesis. 14, 173-179.
71. Shirasu, Y., Moriya, M., Kato, K., Tezuka, H., Teramoto, S., Ohta, T. and Inoue, T. (1982) Mutagenicity screening studies on pesticides. In Sugimura, T., Kondo, S. and Takebe, H. (eds), Environmental Mutagens and Carcinogens. University of Tokyo Press, Tokyo, Japan, pp. 331-335.
72. Spriggs, E.L., Rademaker, A.W. and Martin, R.H. (1995) Aneuploidy in human sperm: results of two-and three-color fluorescence in situ hybridization using centromeric probes for chromosomes 1, 12, 15, 18, X and Y in the young adult mice. Cytogenet. Cell Genet., 71, 47-53.
73. Spriggs, E.L., Rademaker, A.W. and Martin, R.H. (1996) Aneuploidy in human sperm: the use of multicolor FISH to test various theories of non-disjunction. Am. J. Hum. Genet., 58, 356-362.
74. Staples, R.E. and Goulding, E.H. (1979) Dipterex teratogenicity in the rat, hamster and mouse when given by gavage. Environ. Health Perspect., 30, 105-113.
75. Tariot, P.N., Schreider, L. and Porsteinsson, A.P. (1997) Treating Alzheimer's disease: pharmacologic opinions now and in the near future. Postgrad. Med., 101, 73-76.
76. Van Die, J. (1957) The inhibition of serum cholinesterase by O,O-dimethyl-1-hydroxyethyl-phosphonate and 0,0-dimethyl-2,2-dichlorovinyl-phosphonate. Proc. K. Ned. Akad. Wet. B. 60, 227-233.
77. Vig, B.K. (1993) Chromosome segregation and aneuploidy. In Vig, B.K. (ed.), NATO ASI Series H: Cell Biology, Vol. 72. Springer, Berlin, Germany.
78. Warburton, D. and Kinney, A. (1996) Chromosomal differences in susceptiblility to meiotic aneuploidy. Environ. Mol. Mutagen., 28, 237-247.
79. Waters, M.D., Nesnow, S., Simmon, V.F., Mitchell, A.D., Jorgenson, T.A. and Valencia, R. (1981) Pesticides: mutagenic and carcinogenic potential. In Bandal, S.K., Golber, L. and Leng, M.L. (eds), The Pesticide Chemist and Modern Toxicology, ACs Symposium Series no. 160. American Chemical Society, Washington, DC, pp. 80-113.
80. Waters, M.D., Sandhu, S.S., Simmon, V.F., Mortelmans, K.E., Mitchell, A.D., Jorgenson, T.A., Jones, D.C.L., Valencia, R. and Garret, N.E. (1982) Study of pesticide genotoxicity. Basic Life Sci., 21, 275-326.
81. Wegner, D. (1970) Bilarcil® Bay 2349 - clinical experience 1960-1969, unpublished report submitted to WHO. Bayer AG, Wuppertal, Germany.
82. Williams, B., Ballenger, C., Maiter, H., Bishop, F., Tucker, M., Zwingman, T. and Hassold, T. (1993) Non-disjunction in human sperm: results of fluorescence in situ hybridization studies using two and three probes. Hum. Mol. Genet., 11, 1929-1936.
83. World Health Organization (1991) International Programme on Chemical Safety: Trichlorfon, Health Safety Guide no. 66. WHO. Geneva, Switzerland.
84. Wyrobek, A.J. (1993) Methods and concepts in detecting abnormal reproductive outcomes of paternal origin. J. Reprod. Toxicol., 7, 3-16.
85. Wyrobek, A.J. and Adler, I.-D. (1996) Detection of aneuploidy in human and rodent sperm using FISH and applications of sperm assays of genetic damage in heritable risk evaluation. Mutat. Res., 352, 173-179.
86. Wyrobek, A.J., Alhborn, T., Balhorn, R., Stanker, L. and Pinkel, D. (1990) Fluorescence in situ hybridization to Y chromosome in decondensed human sperm nuclei. Mol. Reprod. Dev., 27, 200-208.
87. Wyrobek, A.J., Lowe, X., Pinkel, D. and Bishop, J. (1994) Aneuploidy in late-step spermatids of mice detected by two chromosome fluorescence in situ hybridization. Mol. Reprod. Dev., 40, 259-266.
88. Yamano, T. and Morita, S. (1992) Hepatotoxicity of trichlorfon and dichlorvos in isolated rat hepatocytes. Toxicology, 76, 69-77.
89. Yin, H., Cukurcam, S., Betzendahl, I., Adler, I.-D. and Eichenlaub-Ritter, U. (1998) Trichlorfon exposure, spindle aberrations and nondisjunction in mammalian oocytes. Chromosoma, 107, 514-522.