메뉴 건너뛰기




Volumn 162, Issue 11, 1999, Pages 6492-6502

Genetic dissection of Sle pathogenesis: Sle3 on murine chromosome 7 impacts T cell activation, differentiation, and cell death

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN;

EID: 0033151971     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (158)

References (90)
  • 1
    • 0028858002 scopus 로고
    • Lupus: Key pathogenic mechanisms and contributing factors
    • Mohan, C., and S. K. Datta. 1995. Lupus: key pathogenic mechanisms and contributing factors, Clin. Immunol. Immunopathol. 77:209.
    • (1995) Clin. Immunol. Immunopathol. , vol.77 , pp. 209
    • Mohan, C.1    Datta, S.K.2
  • 2
    • 0028869486 scopus 로고
    • The basis of autoimmunity. I. Mechanisms of aberrant self-recognition
    • Theofilopoulos, A. N. 1995. The basis of autoimmunity. I. Mechanisms of aberrant self-recognition. Immunol. Today 16:90.
    • (1995) Immunol. Today , vol.16 , pp. 90
    • Theofilopoulos, A.N.1
  • 3
    • 0029994333 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Kotzin, B. L. 1996. Systemic lupus erythematosus. Cell 85:303.
    • (1996) Cell , vol.85 , pp. 303
    • Kotzin, B.L.1
  • 4
    • 0030795775 scopus 로고    scopus 로고
    • Genetic dissection of lupus nephritis in murine models of SLE
    • Wakeland, E. K., L. Morel, C. Mohan, and M. Yui. 1997. Genetic dissection of lupus nephritis in murine models of SLE. J. Clin. Immunol. 17:272.
    • (1997) J. Clin. Immunol. , vol.17 , pp. 272
    • Wakeland, E.K.1    Morel, L.2    Mohan, C.3    Yui, M.4
  • 5
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • Vyse, T. J., and J. A. Todd. 1996. Genetic analysis of autoimmune disease. Cell 85:311.
    • (1996) Cell , vol.85 , pp. 311
    • Vyse, T.J.1    Todd, J.A.2
  • 7
    • 0027230775 scopus 로고
    • Differences in expression of lupus nephritis in New Zealand Mixed H-2z homozygous inbred strains of mice derived from New Zealand Black and New Zealand White mice: Origins and initial characterization
    • Rudofsky, U. H., B. D. Evans, S. L. Balaban, V. D. Mottironi, and A. E. Gabrielsen. 1993. Differences in expression of lupus nephritis in New Zealand Mixed H-2z homozygous inbred strains of mice derived from New Zealand Black and New Zealand White mice: origins and initial characterization. Lab. Invest. 68:419.
    • (1993) Lab. Invest. , vol.68 , pp. 419
    • Rudofsky, U.H.1    Evans, B.D.2    Balaban, S.L.3    Mottironi, V.D.4    Gabrielsen, A.E.5
  • 8
    • 0031657151 scopus 로고    scopus 로고
    • Splenic B1a cell expansion in NZM2410 lupus strain, with strong antigen presenting capability
    • Mohan, C., L. Morel, P. Yang, and E. K. Wakeland. 1998. Splenic B1a cell expansion in NZM2410 lupus strain, with strong antigen presenting capability. Arthritis Rheum. 41:1652.
    • (1998) Arthritis Rheum. , vol.41 , pp. 1652
    • Mohan, C.1    Morel, L.2    Yang, P.3    Wakeland, E.K.4
  • 13
    • 0030959717 scopus 로고    scopus 로고
    • Speed congenic: A classic technique moves into the fast lane (relatively speaking)
    • Wakeland, E. K., L. Morel, K. Achey, M. E. Yui, and J. A. Longmate. 1998. Speed congenic: a classic technique moves into the fast lane (relatively speaking). Immunol. Today 18:473.
    • (1998) Immunol. Today , vol.18 , pp. 473
    • Wakeland, E.K.1    Morel, L.2    Achey, K.3    Yui, M.E.4    Longmate, J.A.5
  • 14
    • 0030140063 scopus 로고    scopus 로고
    • Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain
    • Morel, L., Y. Yu, K. R. Blenman, R. A. Caldwell, and E. K. Wakeland. 1996. Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strain. Mamm. Genome 7:335.
    • (1996) Mamm. Genome , vol.7 , pp. 335
    • Morel, L.1    Yu, Y.2    Blenman, K.R.3    Caldwell, R.A.4    Wakeland, E.K.5
  • 16
    • 0031179651 scopus 로고    scopus 로고
    • Genetic dissection of SLE pathogenesis: Sle2 on murine chromosome 4 leads to B-cell hyperactivity
    • Mohan, C., L. Morel, B. Croker, P. Yang, and E. K. Wakeland. 1997. Genetic dissection of SLE pathogenesis: Sle2 on murine chromosome 4 leads to B-cell hyperactivity. J. Immunol. 159:454.
    • (1997) J. Immunol. , vol.159 , pp. 454
    • Mohan, C.1    Morel, L.2    Croker, B.3    Yang, P.4    Wakeland, E.K.5
  • 17
    • 0032520923 scopus 로고    scopus 로고
    • Genetic dissection of SLE pathogenesis: Sle1 on murine chromosome 1 leads to loss of tolerance to H2A/H2B/DNA subnucleosomes
    • Mohan, C., E. Alas, L. Morel, P. Yang, and E. K. Wakeland. 1997. Genetic dissection of SLE pathogenesis: Sle1 on murine chromosome 1 leads to loss of tolerance to H2A/H2B/DNA subnucleosomes. J. Clin. Invest. 101:1362.
    • (1997) J. Clin. Invest. , vol.101 , pp. 1362
    • Mohan, C.1    Alas, E.2    Morel, L.3    Yang, P.4    Wakeland, E.K.5
  • 18
    • 0027477318 scopus 로고
    • Nucleosome: A major immunogen for pathogenic autoantibody-inducing T cells of lupus
    • Mohan, C., S. Adams, V. Stanik, and S. K. Datta. 1993. Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus. J. Exp. Med. 177:1367.
    • (1993) J. Exp. Med. , vol.177 , pp. 1367
    • Mohan, C.1    Adams, S.2    Stanik, V.3    Datta, S.K.4
  • 19
    • 0028852328 scopus 로고
    • Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis
    • Mohan, C., Y. Shi, J. D. Laman, and S. K. Datta. 1995. Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J. Immunol. 154:1470.
    • (1995) J. Immunol. , vol.154 , pp. 1470
    • Mohan, C.1    Shi, Y.2    Laman, J.D.3    Datta, S.K.4
  • 20
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and Bow cytometry
    • Nicoletti, I., G. Migliorati, M. C. Pagliacci, F. Grignani, and C. Riccardi. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and Bow cytometry. J. Immunol. Methods 139:271.
    • (1991) J. Immunol. Methods , vol.139 , pp. 271
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 21
    • 0029043888 scopus 로고
    • A novel assay for apoptosis: Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V
    • Vermes, I., C. Haanen, N. H. Steffens, and C. Reutelingsperger. 1995. A novel assay for apoptosis: flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J. Immunol. Methods 184:39.
    • (1995) J. Immunol. Methods , vol.184 , pp. 39
    • Vermes, I.1    Haanen, C.2    Steffens, N.H.3    Reutelingsperger, C.4
  • 22
    • 0028283552 scopus 로고
    • Evidence for polyclonal T cell activation in murine models of systemic lupus erythematosus
    • Rozzo, S. J., C. G. Drake, B. L. Chiang, M. E. Gershwin, and B. L. Kotzin. 1994. Evidence for polyclonal T cell activation in murine models of systemic lupus erythematosus. J. Immunol. 153:1340.
    • (1994) J. Immunol. , vol.153 , pp. 1340
    • Rozzo, S.J.1    Drake, C.G.2    Chiang, B.L.3    Gershwin, M.E.4    Kotzin, B.L.5
  • 23
    • 0021333156 scopus 로고
    • 1 mice: Evidence for abnormality of the mesenteric lymph node cells
    • 1 mice: evidence for abnormality of the mesenteric lymph node cells. J. Immunol. 132:1265.
    • (1984) J. Immunol. , vol.132 , pp. 1265
    • Jung, L.K.1    Good, R.A.2    Fernandas, G.3
  • 24
    • 0026730836 scopus 로고
    • Evidence for early-onset, polyclonal activation of T cell subsets in mice homozygous for lpr
    • Giese, T., and W. F. Davidson. 1992. Evidence for early-onset, polyclonal activation of T cell subsets in mice homozygous for lpr. J. Immunol. 149:3097.
    • (1992) J. Immunol. , vol.149 , pp. 3097
    • Giese, T.1    Davidson, W.F.2
  • 25
    • 0002645277 scopus 로고
    • T lymphocytes, cytokines, and immune regulation in systemic lupus erythematosus
    • D. J. Wallace, and B. H. Hahn, eds. Lea and Febiger, Philadelphia
    • Horwitz, D. A., and W. T. Stohl. 1993. T lymphocytes, cytokines, and immune regulation in systemic lupus erythematosus. In Dubois' Lupus Erythematosus. D. J. Wallace, and B. H. Hahn, eds. Lea and Febiger, Philadelphia, pp. 83-96.
    • (1993) Dubois' Lupus Erythematosus , pp. 83-96
    • Horwitz, D.A.1    Stohl, W.T.2
  • 26
    • 0030587080 scopus 로고    scopus 로고
    • The natural history of disease expression in CD4 and CD8 gene-deleted New Zealand Black (NZB) mice
    • Chen, S. Y., Y. Takeoka, A. A. Ansari, R. Boyd, D. M. Klinman, and M. E. Gershwin. 1996. The natural history of disease expression in CD4 and CD8 gene-deleted New Zealand Black (NZB) mice. J. Immunol. 157:2676.
    • (1996) J. Immunol. , vol.157 , pp. 2676
    • Chen, S.Y.1    Takeoka, Y.2    Ansari, A.A.3    Boyd, R.4    Klinman, D.M.5    Gershwin, M.E.6
  • 28
    • 0021965670 scopus 로고
    • 1 mice with monoclonal antibody to L3T4
    • 1 mice with monoclonal antibody to L3T4. J. Exp. Med. 161:378.
    • (1985) J. Exp. Med. , vol.161 , pp. 378
    • Wofsy, D.1    Seaman, W.E.2
  • 29
    • 0023256118 scopus 로고
    • Induction of a cationic shift in IgG anti-DNA autoantibodies: Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis
    • Datta, S. K., H. Patel, and D. Berry. 1987. Induction of a cationic shift in IgG anti-DNA autoantibodies: role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis. J. Exp. Med. 165:1252.
    • (1987) J. Exp. Med. , vol.165 , pp. 1252
    • Datta, S.K.1    Patel, H.2    Berry, D.3
  • 32
    • 0024341842 scopus 로고
    • + T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis
    • + T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis. J. Immunol. 143:103.
    • (1989) J. Immunol. , vol.143 , pp. 103
    • Shivakumar, S.1    Tsokos, G.C.2    Datta, S.K.3
  • 33
    • 0029164734 scopus 로고
    • TCR/CD3 complex-mediated signal transduction pathway in T cells and T cell lines from patients with systemic lupus erythematosus
    • Vassilopoulos, D., B. Kovacs, and G. C. Tsokos. 1995. TCR/CD3 complex-mediated signal transduction pathway in T cells and T cell lines from patients with systemic lupus erythematosus. J. Immunol. 155:2269.
    • (1995) J. Immunol. , vol.155 , pp. 2269
    • Kovacs, B.1    Tsokos, G.C.2
  • 34
    • 0032036481 scopus 로고    scopus 로고
    • Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythemalosus: Deficient expression of the T cell receptor ζ chain
    • Liossis, S. N., X. Z. Ding, G. J. Dennis, and G. C. Tsokos. 1998. Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythemalosus: deficient expression of the T cell receptor ζ chain. J. Clin. Invest. 101:1448.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1448
    • Liossis, S.N.1    Ding, X.Z.2    Dennis, G.J.3    Tsokos, G.C.4
  • 35
    • 0026602547 scopus 로고
    • Lymphocyte abnormalities in human lupus
    • Tsokos, G. C. 1992. Lymphocyte abnormalities in human lupus. Clin. Immunol. Immunopathol. 63:7.
    • (1992) Clin. Immunol. Immunopathol. , vol.63 , pp. 7
    • Tsokos, G.C.1
  • 37
    • 0030587119 scopus 로고    scopus 로고
    • Deficient type I protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes. II. Abnormal isozyme kinetics
    • Kammer, G. M., I. U. Khan, J. A. Kammer, I. Olorenshaw, and D. Mathis. 1996. Deficient type I protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes. II. Abnormal isozyme kinetics. J. Immunol. 157:2690.
    • (1996) J. Immunol. , vol.157 , pp. 2690
    • Kammer, G.M.1    Khan, I.U.2    Kammer, J.A.3    Olorenshaw, I.4    Mathis, D.5
  • 39
    • 0021173447 scopus 로고
    • Induction of various autoantibodies by mutant gene lpr in several strains of mice
    • Izui, S., V. E. Kelley, K. Masuda, H. Yoshida, J. B. Roths, and E. D. Murphy. 1984. Induction of various autoantibodies by mutant gene lpr in several strains of mice. J. Immunol. 133:227.
    • (1984) J. Immunol. , vol.133 , pp. 227
    • Izui, S.1    Kelley, V.E.2    Masuda, K.3    Yoshida, H.4    Roths, J.B.5    Murphy, E.D.6
  • 40
    • 0030560974 scopus 로고    scopus 로고
    • Defective CD3-mediated cell death in activated T cells from patients with systemic lupus erythematosus
    • Kovacs, B., D. Vassilopoulos, S. A. Vogelgesang, and G. C. Tsokos. 1996. Defective CD3-mediated cell death in activated T cells from patients with systemic lupus erythematosus. Clin. Immunol. Immunopathol. 81:293.
    • (1996) Clin. Immunol. Immunopathol. , vol.81 , pp. 293
    • Kovacs, B.1    Vassilopoulos, D.2    Vogelgesang, S.A.3    Tsokos, G.C.4
  • 43
    • 0027971945 scopus 로고
    • Apoptosis in SLE: Too little or too much?
    • Elkon, K. B. 1994. Apoptosis in SLE: too little or too much? Clin. Exp. Rheumatol 12:553.
    • (1994) Clin. Exp. Rheumatol , vol.12 , pp. 553
    • Elkon, K.B.1
  • 44
    • 0030777869 scopus 로고    scopus 로고
    • Detection of restricted junctional diversity of peripheral T cells in SLE patients by spectratyping
    • Kolowos, W., M. Hermann, B. B. Ponner, R. Voll, P. Kern, C. Frank, and J. R. Kalden. 1997. Detection of restricted junctional diversity of peripheral T cells in SLE patients by spectratyping. Lupus 6:701.
    • (1997) Lupus , vol.6 , pp. 701
    • Kolowos, W.1    Hermann, M.2    Ponner, B.B.3    Voll, R.4    Kern, P.5    Frank, C.6    Kalden, J.R.7
  • 46
    • 0029815214 scopus 로고    scopus 로고
    • Restrictions of T cell receptor β chain repertoire in the peripheral blood of patients with systemic lupus erythematosus
    • Holbrook, M. R., P. J. Tighe, and R. J. Powell. 1996. Restrictions of T cell receptor β chain repertoire in the peripheral blood of patients with systemic lupus erythematosus. Ann. Rheum. Dis. 55:627.
    • (1996) Ann. Rheum. Dis. , vol.55 , pp. 627
    • Holbrook, M.R.1    Tighe, P.J.2    Powell, R.J.3
  • 47
    • 0029953857 scopus 로고    scopus 로고
    • Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus
    • Kaliyaperumal, A., C. Mohan, W. Wu, and S. K. Datta. 1996. Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus. J. Exp. Med. 183:2459.
    • (1996) J. Exp. Med. , vol.183 , pp. 2459
    • Kaliyaperumal, A.1    Mohan, C.2    Wu, W.3    Datta, S.K.4
  • 48
    • 0028798616 scopus 로고
    • Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus
    • Desai-Mehta, A., C. Mao, S. Rajagopalan, T. Robinson, and S. K. Datta. 1995. Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus. J. Clin. Invest. 95:531.
    • (1995) J. Clin. Invest. , vol.95 , pp. 531
    • Desai-Mehta, A.1    Mao, C.2    Rajagopalan, S.3    Robinson, T.4    Datta, S.K.5
  • 49
    • 10144242672 scopus 로고    scopus 로고
    • dsDNA-, nucleohistone-and DNasc I-reactive T lymphocytes in patients affected by systemic lupus erythematosus: Correlation with clinical disease activity
    • Filaci, G., I. Grasso, P. Contini, M. A. Imro, L. Lanza, M. Scudeletti, E. Rossi, F. Puppo, E. Damasio, and F. Indiveri. 1996. dsDNA-, nucleohistone-and DNasc I-reactive T lymphocytes in patients affected by systemic lupus erythematosus: correlation with clinical disease activity. Clin. Exp. Rheumatol. 14:543.
    • (1996) Clin. Exp. Rheumatol. , vol.14 , pp. 543
    • Filaci, G.1    Grasso, I.2    Contini, P.3    Imro, M.A.4    Lanza, L.5    Scudeletti, M.6    Rossi, E.7    Puppo, F.8    Damasio, E.9    Indiveri, F.10
  • 50
    • 0029069499 scopus 로고
    • T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus
    • Singh, R. R., V. Kumar, F. M. Ebling, S. Southwood, A. Sette, E. E. Sercarz, and B. H. Hahn. 1995. T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus. J. Exp. Med. 181: 2017.
    • (1995) J. Exp. Med. , vol.181 , pp. 2017
    • Singh, R.R.1    Kumar, V.2    Ebling, F.M.3    Southwood, S.4    Sette, A.5    Sercarz, E.E.6    Hahn, B.H.7
  • 52
    • 0031444224 scopus 로고    scopus 로고
    • Histone-specific Th0 and Th1 clones derived from systemic lupus erythematosus patients induce double-stranded DNA antibody production
    • Voll, R. E., E.A. Roth, I. Girkontaite, H. Fehr, M. Hermann, H. M. Lorenz, and J. R. Kalden. 1997. Histone-specific Th0 and Th1 clones derived from systemic lupus erythematosus patients induce double-stranded DNA antibody production. Arthritis Rheum. 40:2162.
    • (1997) Arthritis Rheum. , vol.40 , pp. 2162
    • Voll, R.E.1    Roth, E.A.2    Girkontaite, I.3    Fehr, H.4    Hermann, M.5    Lorenz, H.M.6    Kalden, J.R.7
  • 53
    • 0028229905 scopus 로고
    • Autoantigen-specific T cell proliferation induced by the ribosomal P2 protein in patients with systemic lupus erythematosus
    • Crow, M. K., A. G. DelGiudice, J. B. Zehetbauer, J. L. Lawson, N. Brot, H. Weissbach, and K. B. Elkon. 1994. Autoantigen-specific T cell proliferation induced by the ribosomal P2 protein in patients with systemic lupus erythematosus. J. Clin. Invest. 94:345.
    • (1994) J. Clin. Invest. , vol.94 , pp. 345
    • Crow, M.K.1    DelGiudice, A.G.2    Zehetbauer, J.B.3    Lawson, J.L.4    Brot, N.5    Weissbach, H.6    Elkon, K.B.7
  • 54
    • 0032502801 scopus 로고    scopus 로고
    • Homeostasis and self-tolerance in the immune system: Turning lymphocytes off
    • Van, P. L., and A. K. Abbas. 1998. Homeostasis and self-tolerance in the immune system: turning lymphocytes off. Science 280:243.
    • (1998) Science , vol.280 , pp. 243
    • Van, P.L.1    Abbas, A.K.2
  • 55
    • 0025875259 scopus 로고
    • lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease
    • Cohen, P. L., and R. A. Eisenberg. 1991. lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol. 9:243.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 243
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 56
    • 0028980902 scopus 로고
    • Fas and Fas ligand: Lpr and gld mutations
    • Nagata, S., and T. Suda. 1995. Fas and Fas ligand: lpr and gld mutations. Immunol. Today 16:39.
    • (1995) Immunol. Today , vol.16 , pp. 39
    • Nagata, S.1    Suda, T.2
  • 57
    • 0029414791 scopus 로고
    • Role of the common cytokine receptor Y chain in cytokine signaling and lymphoid development
    • Leonard, W. J., E. W. Shores, and P. E. Love. 1995. Role of the common cytokine receptor Y chain in cytokine signaling and lymphoid development. Immunol. Rev. 148:97.
    • (1995) Immunol. Rev. , vol.148 , pp. 97
    • Leonard, W.J.1    Shores, E.W.2    Love, P.E.3
  • 60
    • 0028878330 scopus 로고
    • Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor y chain
    • DiSanto, J. P., W. Muller, G. D. Guy, A. Fischer, and K. Rajewsky. 1995. Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor y chain. Proc. Natl. Acad. Sci. USA 92:377.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 377
    • Disanto, J.P.1    Muller, W.2    Guy, G.D.3    Fischer, A.4    Rajewsky, K.5
  • 64
    • 0031041301 scopus 로고    scopus 로고
    • The common cytokine receptor y chain plays an essential role in regulating lymphoid homeostasis
    • Nakajima, H., E. W. Shores, M. Noguchi, and W. J. Leonard. 1997. The common cytokine receptor y chain plays an essential role in regulating lymphoid homeostasis. J. Exp. Med. 185:189.
    • (1997) J. Exp. Med. , vol.185 , pp. 189
    • Nakajima, H.1    Shores, E.W.2    Noguchi, M.3    Leonard, W.J.4
  • 65
    • 0031573076 scopus 로고    scopus 로고
    • Impaired peripheral deletion of activated T cells in mice lacking the common cytokine receptor γ-chain
    • Nakajima, H., and W. J. Leonard. 1997. Impaired peripheral deletion of activated T cells in mice lacking the common cytokine receptor γ-chain. J. Immunol. 159: 4737.
    • (1997) J. Immunol. , vol.159 , pp. 4737
    • Nakajima, H.1    Leonard, W.J.2
  • 66
    • 1842291572 scopus 로고    scopus 로고
    • Crucial role of Jak3 in negative selection of self-reactive T cells
    • Saijo, K., S. Y. Park, Y. Ishida, H. Arase, and T. Saito. 1997. Crucial role of Jak3 in negative selection of self-reactive T cells. J. Exp. Med. 185:351.
    • (1997) J. Exp. Med. , vol.185 , pp. 351
    • Saijo, K.1    Park, S.Y.2    Ishida, Y.3    Arase, H.4    Saito, T.5
  • 67
    • 0029864365 scopus 로고    scopus 로고
    • Critical role for the common cytokine receptor γ chain in intrathymic and peripheral T cell selection
    • DiSanto, J. P., G. D. Guy, A. Fisher, and A. Tarakhovsky. 1996. Critical role for the common cytokine receptor γ chain in intrathymic and peripheral T cell selection. J. Exp. Med. 183:1111.
    • (1996) J. Exp. Med. , vol.183 , pp. 1111
    • Disanto, J.P.1    Guy, G.D.2    Fisher, A.3    Tarakhovsky, A.4
  • 68
    • 0031569514 scopus 로고    scopus 로고
    • Functional responses and apoptosis of CD25 (IL-2Ra)-deficient T cells expressing a transgenic antigen receptor
    • Parijs, L. V., A. Biuckians, A. Ibragimov, F. W. Alt, D. M. Willerford, and A. K. Abbas. 1997. Functional responses and apoptosis of CD25 (IL-2Ra)-deficient T cells expressing a transgenic antigen receptor. J. Immunol. 158:3738.
    • (1997) J. Immunol. , vol.158 , pp. 3738
    • Parijs, L.V.1    Biuckians, A.2    Ibragimov, A.3    Alt, F.W.4    Willerford, D.M.5    Abbas, A.K.6
  • 69
    • 0029118133 scopus 로고
    • Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice
    • Kneitz, B., T. Herrmann, S. Yonehara, and A. Schimpl. 1995. Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice. Eur. J. Immunol. 25:2572.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 2572
    • Kneitz, B.1    Herrmann, T.2    Yonehara, S.3    Schimpl, A.4
  • 71
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol, E. A., F. Borriello, A. N. Schweitzer, W. P. Lynch, J. A. Bluestone, and A. H. Sharpe. 1995. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3:541.
    • (1995) Immunity , vol.3 , pp. 541
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 73
    • 0031159039 scopus 로고    scopus 로고
    • Abnormal T lymphocyte development induced by targeted overexpression of IkB α
    • Esslinger, C. W., A. Wilson, B. Sordat, F. Beermann, and C. V. Jongeneel. 1997. Abnormal T lymphocyte development induced by targeted overexpression of IkB α. J. Immunol. 158:5075.
    • (1997) J. Immunol. , vol.158 , pp. 5075
    • Esslinger, C.W.1    Wilson, A.2    Sordat, B.3    Beermann, F.4    Jongeneel, C.V.5
  • 74
    • 0030925372 scopus 로고    scopus 로고
    • Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive represser of nuclear factor (NF)-kB
    • Boothby, M. R., A. L. Mora, D. C. Scherer, J. A. Brockman, and D. W. Ballard. 1997. Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive represser of nuclear factor (NF)-kB. J. Exp. Med. 185:1897.
    • (1997) J. Exp. Med. , vol.185 , pp. 1897
    • Boothby, M.R.1    Mora, A.L.2    Scherer, D.C.3    Brockman, J.A.4    Ballard, D.W.5
  • 75
    • 0031159205 scopus 로고    scopus 로고
    • Multifocal defects in immune responses in RelB-deficient mice
    • Weih, F., G. Warr, H. Yang, and R. Bravo. 1997. Multifocal defects in immune responses in RelB-deficient mice. J. Immunol. 158:5211.
    • (1997) J. Immunol. , vol.158 , pp. 5211
    • Weih, F.1    Warr, G.2    Yang, H.3    Bravo, R.4
  • 77
    • 0028292001 scopus 로고
    • Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase
    • Elder, M. E., D. Lin, J. Clever, A. C. Chan, T. J. Hope, A. Weiss, and T. G. Parslow. 1994. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science 264:1596.
    • (1994) Science , vol.264 , pp. 1596
    • Elder, M.E.1    Lin, D.2    Clever, J.3    Chan, A.C.4    Hope, T.J.5    Weiss, A.6    Parslow, T.G.7
  • 78
    • 0021924611 scopus 로고
    • Induction of severe autoimmune disease in normal mice by simultaneous action of multiple immunostimulators
    • Hang, L. M., M. T. Aguado, F. J. Dixon, and A. N. Theofilopoulos. 1985. Induction of severe autoimmune disease in normal mice by simultaneous action of multiple immunostimulators. J. Exp. Med. 161:423.
    • (1985) J. Exp. Med. , vol.161 , pp. 423
    • Hang, L.M.1    Aguado, M.T.2    Dixon, F.J.3    Theofilopoulos, A.N.4
  • 81
    • 0030499431 scopus 로고    scopus 로고
    • CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-dencient mice
    • Sato, S., A. S. Miller, M. Inaoki, C. B. Bock, P. J. Jansen, M. L. Tang, and T. F. Tedder. 1996. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-dencient mice. Immunity 5:551.
    • (1996) Immunity , vol.5 , pp. 551
    • Sato, S.1    Miller, A.S.2    Inaoki, M.3    Bock, C.B.4    Jansen, P.J.5    Tang, M.L.6    Tedder, T.F.7
  • 86
    • 0028990699 scopus 로고
    • SLE-like autoantibodies and Sjögren's syndrome-like lymphoproliferation in TGF-β knockout mice
    • Dang, H., A. G. Geiser, J. J. Letterio, T. Nakabayashi, L. Kong, G. Fernandes, and N. Talal. 1995. SLE-like autoantibodies and Sjögren's syndrome-like lymphoproliferation in TGF-β knockout mice. J. Immunol. 155:3205.
    • (1995) J. Immunol. , vol.155 , pp. 3205
    • Dang, H.1    Geiser, A.G.2    Letterio, J.J.3    Nakabayashi, T.4    Kong, L.5    Fernandes, G.6    Talal, N.7
  • 88
  • 89
    • 0031278336 scopus 로고    scopus 로고
    • B cell antigen receptor-evoked calcium influx is enhanced in CD22-deficient B cell lines
    • Nadler, M. J., P. A. McLean, B. G. Neel, and H. H. Wortis. 1997. B cell antigen receptor-evoked calcium influx is enhanced in CD22-deficient B cell lines. J. Immunol. 159:4233.
    • (1997) J. Immunol. , vol.159 , pp. 4233
    • Nadler, M.J.1    McLean, P.A.2    Neel, B.G.3    Wortis, H.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.