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Volumn 7, Issue 14, 1997, Pages 1879-1882

Development of a positron emission tomography radiopharmaceutical for imaging thymidine kinase gene expression: Synthesis and in vitro evaluation of 9-{(3-[18F]fluoro-1-hydroxy-2-propoxy)methyl{guanine

Author keywords

[No Author keywords available]

Indexed keywords

9 [(3 FLUORO 2 HYDROXY 2 PROPOXY)METHYL]GUANINE; ACICLOVIR; ANTIVIRUS AGENT; FLUORINE 18; GANCICLOVIR; THYMIDINE KINASE; TRACER; UNCLASSIFIED DRUG;

EID: 0030739708     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00325-9     Document Type: Article
Times cited : (28)

References (17)
  • 8
    • 0343139143 scopus 로고    scopus 로고
    • note
    • +: 564
  • 16
    • 0342269663 scopus 로고    scopus 로고
    • note
    • An authentic sample of FHPG monophosphate was prepared by treating N-acetyl-FHPG with 2-cyanoethyl N,N-diisopropylchlorophosphoramidite. Conversion to the intermediate dicyanoethylphosphoramidite and subsequent oxidation, deprotection and purification by HPLC on a SAX column afforded the desired compound.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.