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Volumn 40, Issue 6, 1999, Pages 995-1002

Potential applications of PET imaging in developing novel cancer therapies

Author keywords

Gene therapy; PET

Indexed keywords

CANCER GENETICS; CANCER THERAPY; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; HUMAN; MALIGNANT NEOPLASTIC DISEASE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REVIEW;

EID: 0033067830     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (36)

References (73)
  • 6
    • 0031833036 scopus 로고    scopus 로고
    • Cancer gene therapy: Connecting basic research with clinical inquiry
    • Dranoff G. Cancer gene therapy: connecting basic research with clinical inquiry. J Clin Oncol. 1998;16:2548-2556.
    • (1998) J Clin Oncol. , vol.16 , pp. 2548-2556
    • Dranoff, G.1
  • 7
    • 0024041143 scopus 로고
    • Antiviral activity and mechanism of action of anciclovir
    • Matthews T, Boehme R. Antiviral activity and mechanism of action of anciclovir. Rev Infect Dis. 1988;10:5490-5494.
    • (1988) Rev Infect Dis. , vol.10 , pp. 5490-5494
    • Matthews, T.1    Boehme, R.2
  • 8
    • 0031463632 scopus 로고    scopus 로고
    • Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
    • Ram Z, Culver KW, Oshiro EM, et al. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nat Med. 1997;3: 1354-1361.
    • (1997) Nat Med. , vol.3 , pp. 1354-1361
    • Ram, Z.1    Culver, K.W.2    Oshiro, E.M.3
  • 9
    • 0032549688 scopus 로고    scopus 로고
    • Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells
    • Yang L, Chiang Y, Lenz HJ, et al. Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells. Hum Gene Ther. 1998;9:719-728.
    • (1998) Hum Gene Ther. , vol.9 , pp. 719-728
    • Yang, L.1    Chiang, Y.2    Lenz, H.J.3
  • 10
    • 0025241769 scopus 로고
    • Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors
    • Moolten FL, Wells JM. Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors. J Natl Cancer Inst. 1990;82:297-300.
    • (1990) J Natl Cancer Inst. , vol.82 , pp. 297-300
    • Moolten, F.L.1    Wells, J.M.2
  • 11
    • 0025444099 scopus 로고
    • Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene
    • Moolten FL, Wells JM, Heyman RA, Evans RM. Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene. Hum Gene Ther. 1990;1:125-134.
    • (1990) Hum Gene Ther. , vol.1 , pp. 125-134
    • Moolten, F.L.1    Wells, J.M.2    Heyman, R.A.3    Evans, R.M.4
  • 12
    • 19244362665 scopus 로고    scopus 로고
    • Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: A phase I trial
    • Eck SL, Alavi JB, Alavi A, et al. Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: a phase I trial. Hum Gene Ther. 1996;7:1465-1482.
    • (1996) Hum Gene Ther. , vol.7 , pp. 1465-1482
    • Eck, S.L.1    Alavi, J.B.2    Alavi, A.3
  • 13
    • 17344365922 scopus 로고    scopus 로고
    • Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: Results of a phase i clinical trial in malignant mesothelioma
    • Sterman DH, Treat J, Litzky LA, et al. Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma. Hum Gene Ther. 1998;9:1083-1092.
    • (1998) Hum Gene Ther. , vol.9 , pp. 1083-1092
    • Sterman, D.H.1    Treat, J.2    Litzky, L.A.3
  • 16
    • 0000833293 scopus 로고    scopus 로고
    • 8-(F-18)fluoroacyclovir: An in-vivo probe for gene expression with PET
    • Barrio JR, Namavari M, Satyamurthy N, et al. 8-(F-18)fluoroacyclovir: an in-vivo probe for gene expression with PET [abstract]. J Nucl Med. 1996;37:193P-194P.
    • (1996) J Nucl Med. , vol.37
    • Barrio, J.R.1    Namavari, M.2    Satyamurthy, N.3
  • 17
    • 0028802564 scopus 로고
    • Imaging the expression of transfected genes in vivo
    • Tjuvajev JG, Stockhammer G, Desai R, et al. Imaging the expression of transfected genes in vivo. Cancer Res. 1995;55:6126-6132.
    • (1995) Cancer Res. , vol.55 , pp. 6126-6132
    • Tjuvajev, J.G.1    Stockhammer, G.2    Desai, R.3
  • 18
    • 0030861693 scopus 로고    scopus 로고
    • Non-invasive scintigraphic monitoring of gene expression in a HS V-1 thymidine kinase gene therapy model
    • Morin KW, Knaus EE, Wiebe LI. Non-invasive scintigraphic monitoring of gene expression in a HS V-1 thymidine kinase gene therapy model. Nucl Med Commun. 1997;18:599-605.
    • (1997) Nucl Med Commun. , vol.18 , pp. 599-605
    • Morin, K.W.1    Knaus, E.E.2    Wiebe, L.I.3
  • 19
    • 0031829740 scopus 로고    scopus 로고
    • 5-Fluoro-1-(2′-deoxy-2′-fluoro-beta-D-ribofuranosyl) uracil trapping in Morris hepatoma cells expressing the herpes simplex virus thymidine kinase gene
    • Germann C, Shields AF, Grierson JR, Morr I, Haberkorn U. 5-Fluoro-1-(2′-deoxy-2′-fluoro-beta-D-ribofuranosyl) uracil trapping in Morris hepatoma cells expressing the herpes simplex virus thymidine kinase gene. J Nucl Med. 1998;39:1418-1423.
    • (1998) J Nucl Med. , vol.39 , pp. 1418-1423
    • Germann, C.1    Shields, A.F.2    Grierson, J.R.3    Morr, I.4    Haberkorn, U.5
  • 20
    • 9544242826 scopus 로고    scopus 로고
    • Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy
    • Tjuvajev JG, Finn R, Watanabe K, et al. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy. Cancer Res. 1996;56:4087-4095.
    • (1996) Cancer Res. , vol.56 , pp. 4087-4095
    • Tjuvajev, J.G.1    Finn, R.2    Watanabe, K.3
  • 21
    • 17144471900 scopus 로고    scopus 로고
    • Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography
    • Tjuvajev JG, Avril N, Oku T, et al. Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res. 1998;58: 4333-4341.
    • (1998) Cancer Res. , vol.58 , pp. 4333-4341
    • Tjuvajev, J.G.1    Avril, N.2    Oku, T.3
  • 22
    • 10144230692 scopus 로고    scopus 로고
    • Quantitative imaging of iodine-124 with PET
    • Pentlow KS, Graham MC, Lambrecht RM, et al. Quantitative imaging of iodine-124 with PET. J Nucl Med. 1996;37:1557-1562.
    • (1996) J Nucl Med. , vol.37 , pp. 1557-1562
    • Pentlow, K.S.1    Graham, M.C.2    Lambrecht, R.M.3
  • 23
    • 0000476126 scopus 로고    scopus 로고
    • Carbon-8 radiofluorination of purines: A general approach to probe design for gene therapy in humans
    • Barrio JR, Namavari M, Srinivasan A, et al. Carbon-8 radiofluorination of purines: a general approach to probe design for gene therapy in humans. J Labelled Compd Radiopharm. 1997;40:348.
    • (1997) J Labelled Compd Radiopharm. , vol.40 , pp. 348
    • Barrio, J.R.1    Namavari, M.2    Srinivasan, A.3
  • 25
    • 0006337915 scopus 로고    scopus 로고
    • 18F)fluoro-1-hydroxy-2-propoxy)methyl)guanine: Radiopharmaceuticals for gene therapy
    • 18F)fluoro-1-hydroxy-2-propoxy)methyl)guanine: radiopharmaceuticals for gene therapy. J Labelled Compd Radiopharm. 1997;40:20-22.
    • (1997) J Labelled Compd Radiopharm. , vol.40 , pp. 20-22
    • Monclus, M.1    Luxen, A.2    Cool, V.3
  • 26
    • 0031039313 scopus 로고    scopus 로고
    • Monitoring gene therapy with herpes simplex virus thymidine kinase in hepatoma cells: Uptake of specific substrates
    • Haberkorn U, Altmann A, Morr I, et al. Monitoring gene therapy with herpes simplex virus thymidine kinase in hepatoma cells: uptake of specific substrates. J Nucl Med. 1997;38:287-294.
    • (1997) J Nucl Med. , vol.38 , pp. 287-294
    • Haberkorn, U.1    Altmann, A.2    Morr, I.3
  • 27
    • 0031981288 scopus 로고    scopus 로고
    • Ganciclovir uptake in human mammary carcinoma cells expressing herpes simplex virus thymidine kinase
    • Haberkorn U, Khazaie K, Morr I, Altmann A, Muller M, van Kaick G. Ganciclovir uptake in human mammary carcinoma cells expressing herpes simplex virus thymidine kinase. Nucl Med Biol. 1998;25:367-373.
    • (1998) Nucl Med Biol. , vol.25 , pp. 367-373
    • Haberkorn, U.1    Khazaie, K.2    Morr, I.3    Altmann, A.4    Muller, M.5    Van Kaick, G.6
  • 28
    • 0031742514 scopus 로고    scopus 로고
    • Imaging of adenoviral-directed herpes simplex virus type I thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir
    • Gambhir SS, Barrio JR, Wu L, et al. Imaging of adenoviral-directed herpes simplex virus type I thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir. J Nucl Med. 1998;39:2003-2011.
    • (1998) J Nucl Med. , vol.39 , pp. 2003-2011
    • Gambhir, S.S.1    Barrio, J.R.2    Wu, L.3
  • 29
    • 0002373628 scopus 로고    scopus 로고
    • Tracer kinetic modeling of 8-(F-18)-fluoroganciclovir PET data: A new tracer for measuring reporter gene expression
    • Green LA, Gambhir SS, Barrio JR, et al. Tracer kinetic modeling of 8-(F-18)-fluoroganciclovir PET data: a new tracer for measuring reporter gene expression [abstract], J Nucl Med. 1998;39:10P.
    • (1998) J Nucl Med. , vol.39
    • Green, L.A.1    Gambhir, S.S.2    Barrio, J.R.3
  • 31
    • 0003319070 scopus 로고    scopus 로고
    • Simplified one-pot synthesis of 9-((3-(F-18)fluoro-1-hydroxy-2-propoxy)methyl)guanine ((F-18)FHPG,2) for gene therapy
    • Shiue CY. Shiue GG, McDonald D, Eck S, Alavi AA. Simplified one-pot synthesis of 9-((3-(F-18)fluoro-1-hydroxy-2-propoxy)methyl)guanine ((F-18)FHPG,2) for gene therapy [abstract]. J Nucl Med. 1998;39:231P.
    • (1998) J Nucl Med. , vol.39
    • Shiue, C.Y.1    Shiue, G.G.2    McDonald, D.3    Eck, S.4    Alavi, A.A.5
  • 32
    • 0030980637 scopus 로고    scopus 로고
    • Three-dimensional imaging characteristics of the HEAD PENN-PET scanner
    • Karp JS, Freifelder R, Geagan MJ, et al. Three-dimensional imaging characteristics of the HEAD PENN-PET scanner. J Nucl Med. 1997;38:636-643.
    • (1997) J Nucl Med. , vol.38 , pp. 636-643
    • Karp, J.S.1    Freifelder, R.2    Geagan, M.J.3
  • 33
    • 18244428952 scopus 로고    scopus 로고
    • 18F]FHBG): A new potential imaging agent for viral infection and gene therapy using PET
    • 18F]FHBG): a new potential imaging agent for viral infection and gene therapy using PET. Nucl Med Biol. 1998;25:175-180.
    • (1998) Nucl Med Biol. , vol.25 , pp. 175-180
    • Alauddin, M.M.1    Conti, P.S.2
  • 34
    • 0026493737 scopus 로고
    • Mode of antiviral action of penciclovir in MRC-5 cells infected with herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus
    • Earnshaw DL, Bacon TH, Darlison SJ, Edmonds K, Perkins RM, Vere Hodge RA. Mode of antiviral action of penciclovir in MRC-5 cells infected with herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus. Antimicrob Agents Chemother. 1992;36:2747-2757.
    • (1992) Antimicrob Agents Chemother. , vol.36 , pp. 2747-2757
    • Earnshaw, D.L.1    Bacon, T.H.2    Darlison, S.J.3    Edmonds, K.4    Perkins, R.M.5    Vere Hodge, R.A.6
  • 35
    • 0021860994 scopus 로고
    • Intracellular metabolism and enzymatic phosphorylation of 9-(1,3-dihydroxy-2-propoxymethyl)guanine and acyclovir in herpes simplex virus-infected and uninfected cells
    • Smee DF, Boehme R, Chernow M, Binko BP, Matthews TR. Intracellular metabolism and enzymatic phosphorylation of 9-(1,3-dihydroxy-2-propoxymethyl)guanine and acyclovir in herpes simplex virus-infected and uninfected cells. Biochem Pharmacol. 1985;34:1049-1056.
    • (1985) Biochem Pharmacol. , vol.34 , pp. 1049-1056
    • Smee, D.F.1    Boehme, R.2    Chernow, M.3    Binko, B.P.4    Matthews, T.R.5
  • 36
    • 0002373630 scopus 로고    scopus 로고
    • Radiolabeled penciclovir: A new reporter probe with improved imaging properties over ganciclovir for imaging herpes-simplex virus type 1 thymidine kinase reporter gene expression
    • Gambhir SS, Barrio JR, Bauer E, et al. Radiolabeled penciclovir: a new reporter probe with improved imaging properties over ganciclovir for imaging herpes-simplex virus type 1 thymidine kinase reporter gene expression [abstract]. J Nucl Med. 1998;39:53P.
    • (1998) J Nucl Med. , vol.39
    • Gambhir, S.S.1    Barrio, J.R.2    Bauer, E.3
  • 37
    • 0030045876 scopus 로고    scopus 로고
    • Development of labeled thymidine analogs for imaging tumor proliferation
    • Shields AF, Grierson JR, Kozawa SM, Zheng M. Development of labeled thymidine analogs for imaging tumor proliferation. Nucl Med Biol. 1996;23: 17-22.
    • (1996) Nucl Med Biol. , vol.23 , pp. 17-22
    • Shields, A.F.1    Grierson, J.R.2    Kozawa, S.M.3    Zheng, M.4
  • 38
    • 0031823233 scopus 로고    scopus 로고
    • Uncoupling of 2-fluoro-2-deoxyglucose transport and phosphorylation in rat hepatoma during gene therapy with HSV thymidine kinase
    • Haberkorn U, Belleman ME, Gerlach L, et al. Uncoupling of 2-fluoro-2-deoxyglucose transport and phosphorylation in rat hepatoma during gene therapy with HSV thymidine kinase. Gene Ther. 1998;5:880-887.
    • (1998) Gene Ther. , vol.5 , pp. 880-887
    • Haberkorn, U.1    Belleman, M.E.2    Gerlach, L.3
  • 39
    • 0030872422 scopus 로고    scopus 로고
    • Multitracer studies during gene therapy of hepatoma cells with herpes simplex virus thymidine kinase and ganciclovir
    • Haberkorn U, Altmann A, Mon I, Germann C, Oberdorfer F, van Kaick G. Multitracer studies during gene therapy of hepatoma cells with herpes simplex virus thymidine kinase and ganciclovir. J Nucl Med. 1997;38:1048-1054.
    • (1997) J Nucl Med. , vol.38 , pp. 1048-1054
    • Haberkorn, U.1    Altmann, A.2    Mon, I.3    Germann, C.4    Oberdorfer, F.5    Van Kaick, G.6
  • 40
    • 0021276479 scopus 로고
    • Hypoxic fractions of solid tumors: Experimental techniques, methods of analysis, and a survey of existing data
    • Moulder JE, Rockwell S. Hypoxic fractions of solid tumors: experimental techniques, methods of analysis, and a survey of existing data. Int J Radiat Oncol Biol Phys. 1984;10:695-712.
    • (1984) Int J Radiat Oncol Biol Phys. , vol.10 , pp. 695-712
    • Moulder, J.E.1    Rockwell, S.2
  • 41
    • 0019864315 scopus 로고
    • Hypoxia-mediated drugs for radiation and chemotherapy
    • Adams GE, Hypoxia-mediated drugs for radiation and chemotherapy. Cancer. 1981;48:696-707.
    • (1981) Cancer , vol.48 , pp. 696-707
    • Adams, G.E.1
  • 42
    • 0027339592 scopus 로고
    • 2 predicts survival in advanced cancer of the uterine cervix
    • 2 predicts survival in advanced cancer of the uterine cervix. Radiother Oncol. 1993;26:45-50.
    • (1993) Radiother Oncol. , vol.26 , pp. 45-50
    • Hockel, M.1    Knoop, C.2    Schlenger, K.3
  • 43
    • 0030022252 scopus 로고    scopus 로고
    • Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma
    • Brizel DM, Scully SP, Harrelson JM, et al. Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res. 1996;56:941-943.
    • (1996) Cancer Res. , vol.56 , pp. 941-943
    • Brizel, D.M.1    Scully, S.P.2    Harrelson, J.M.3
  • 44
    • 0023932431 scopus 로고
    • Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy
    • Gatenby RA, Kessler HB, Rosenblum JS, et al. Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy. Int J Radiat Oncol Biol Phys. 1988;14:831-838.
    • (1988) Int J Radiat Oncol Biol Phys. , vol.14 , pp. 831-838
    • Gatenby, R.A.1    Kessler, H.B.2    Rosenblum, J.S.3
  • 46
    • 0029775242 scopus 로고    scopus 로고
    • Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
    • Hockel M, Schlenger K, Aral B, Mitze M, Schaffer U, Vaupel P. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res. 1996;56:4509-1515.
    • (1996) Cancer Res. , vol.56 , pp. 4509-11515
    • Hockel, M.1    Schlenger, K.2    Aral, B.3    Mitze, M.4    Schaffer, U.5    Vaupel, P.6
  • 50
    • 8544273661 scopus 로고    scopus 로고
    • Interlaboratory variation in oxygen tension measurement by Eppendorf "histograph" and comparison with hypoxic marker
    • Nozue M, Lee I, Yuan F, et al. Interlaboratory variation in oxygen tension measurement by Eppendorf "histograph" and comparison with hypoxic marker. J Surg Oncol. 1997;66:30-38.
    • (1997) J Surg Oncol. , vol.66 , pp. 30-38
    • Nozue, M.1    Lee, I.2    Yuan, F.3
  • 51
    • 0030995145 scopus 로고    scopus 로고
    • Proliferation and hypoxia in human squamous cell carcinoma of the cervix: First report of combined immunohistochemical assays
    • Kennedy AS, Raleigh JA, Perez GM, et al. Proliferation and hypoxia in human squamous cell carcinoma of the cervix: first report of combined immunohistochemical assays. Int J Radiat Oncol Biol Phys. 1997;37:897-905.
    • (1997) Int J Radiat Oncol Biol Phys. , vol.37 , pp. 897-905
    • Kennedy, A.S.1    Raleigh, J.A.2    Perez, G.M.3
  • 52
    • 0025343704 scopus 로고
    • Bioreductive drugs and the selective induction of tumour hypoxia
    • Bremner JC, Stratford IJ, Bowler J, Adams GE. Bioreductive drugs and the selective induction of tumour hypoxia. Br J Cancer. 1990;61:717-721.
    • (1990) Br J Cancer , vol.61 , pp. 717-721
    • Bremner, J.C.1    Stratford, I.J.2    Bowler, J.3    Adams, G.E.4
  • 53
    • 0025204646 scopus 로고
    • Dual-function 2-nitroimidazoles as hypoxic cell radiosensitizers and bioreductive cytotoxins: In vivo evaluation in KHT murine sarcomas
    • Cole S, Stratford IJ, Adams GE, Fielden EM, Jenkins TC. Dual-function 2-nitroimidazoles as hypoxic cell radiosensitizers and bioreductive cytotoxins: in vivo evaluation in KHT murine sarcomas. Radiat Res. 1990;124:S38-S43.
    • (1990) Radiat Res. , vol.124
    • Cole, S.1    Stratford, I.J.2    Adams, G.E.3    Fielden, E.M.4    Jenkins, T.C.5
  • 54
    • 0021685559 scopus 로고
    • The detection and measurement of hypoxic cells in solid tumors
    • Chapman JD. The detection and measurement of hypoxic cells in solid tumors. Cancer. 1984;54:2441-2449.
    • (1984) Cancer , vol.54 , pp. 2441-2449
    • Chapman, J.D.1
  • 55
    • 0026570515 scopus 로고
    • Imaging of hypoxia in human tumors with [F-18]fluoromisonidazole
    • Koh WJ, Rasey JS, Evans ML, et al. Imaging of hypoxia in human tumors with [F-18]fluoromisonidazole. Int J Radiat Oncol Biol Phys. 1992;22:199-212.
    • (1992) Int J Radiat Oncol Biol Phys. , vol.22 , pp. 199-212
    • Koh, W.J.1    Rasey, J.S.2    Evans, M.L.3
  • 57
    • 0028917959 scopus 로고
    • Development of F-18-labeled fluoroerythronitroimidazole as a PET agent for imaging tumor hypoxia
    • Yang DJ, Wallace S, Cherif A, et al. Development of F-18-labeled fluoroerythronitroimidazole as a PET agent for imaging tumor hypoxia. Radiology. 1995;194: 795-800.
    • (1995) Radiology , vol.194 , pp. 795-800
    • Yang, D.J.1    Wallace, S.2    Cherif, A.3
  • 58
    • 0026475672 scopus 로고
    • Hypoxia in human gliomas: Demonstration by PET with fluorine-18-fluoromisonidazole
    • Valk P, Mathis C, Prados M, Gilbert J, Budinger T. Hypoxia in human gliomas: demonstration by PET with fluorine-18-fluoromisonidazole. J Nucl Med. 1992;33: 2133-2137.
    • (1992) J Nucl Med. , vol.33 , pp. 2133-2137
    • Valk, P.1    Mathis, C.2    Prados, M.3    Gilbert, J.4    Budinger, T.5
  • 59
    • 0029145952 scopus 로고
    • Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography
    • Koh WJ, Bergman KS, Rasey JS, et al. Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography, Int J Radiat Oncol Biol Phys. 1995;33:391-398.
    • (1995) Int J Radiat Oncol Biol Phys. , vol.33 , pp. 391-398
    • Koh, W.J.1    Bergman, K.S.2    Rasey, J.S.3
  • 60
    • 0029080196 scopus 로고
    • A modeling approach for quantifying tumor hypoxia with [F-18]fluoromisonidazole PET time-activity data
    • Casciari JJ, Graham MM, Rasey JS. A modeling approach for quantifying tumor hypoxia with [F-18]fluoromisonidazole PET time-activity data. Med Phys. 1995;22:1127-1139.
    • (1995) Med Phys. , vol.22 , pp. 1127-1139
    • Casciari, J.J.1    Graham, M.M.2    Rasey, J.S.3
  • 61
    • 0029800972 scopus 로고    scopus 로고
    • Fluorine-18 fluoromisonidazole tumour to muscle retention ratio for the detection of hypoxia in nasopharyngeal carcinoma
    • Yeh SH, Liu RS, Wu LC, et al. Fluorine-18 fluoromisonidazole tumour to muscle retention ratio for the detection of hypoxia in nasopharyngeal carcinoma. Eur J Nucl Med. 1996;23:1378-1383.
    • (1996) Eur J Nucl Med. , vol.23 , pp. 1378-1383
    • Yeh, S.H.1    Liu, R.S.2    Wu, L.C.3
  • 62
    • 0030608674 scopus 로고    scopus 로고
    • 18F]fluoroetanidazole: A potential new tracer for imaging hypoxia
    • 18F]fluoroetanidazole: a potential new tracer for imaging hypoxia. Nucl Med Biol. 1997;24:755-760.
    • (1997) Nucl Med Biol. , vol.24 , pp. 755-760
    • Tewson, T.J.1
  • 63
    • 0030032543 scopus 로고    scopus 로고
    • 2-Nitroimidazole (EF5) binding predicts radiation resistance in individual 9L s.c. tumors
    • Evans SM, Jenkins WT, Joiner B, Lord EM, Koch CJ. 2-Nitroimidazole (EF5) binding predicts radiation resistance in individual 9L s.c. tumors. Cancer Res. 1996;56:405-411.
    • (1996) Cancer Res. , vol.56 , pp. 405-411
    • Evans, S.M.1    Jenkins, W.T.2    Joiner, B.3    Lord, E.M.4    Koch, C.J.5
  • 65
    • 0030423710 scopus 로고    scopus 로고
    • Biodistribution of the nitroimidazole EF5 (2-[2-nitro-1H-imidazol-1-yl]-N-(2,2,3,3,3-pentafluoropropyl) acetamide) in mice bearing subcutaneous EMT6 tumors
    • Laughlin KM, Evans SM, Jenkins WT, et al. Biodistribution of the nitroimidazole EF5 (2-[2-nitro-1H-imidazol-1-yl]-N-(2,2,3,3,3-pentafluoropropyl) acetamide) in mice bearing subcutaneous EMT6 tumors. J Pharmacol Exp Ther. 1996;277:1049-1057.
    • (1996) J Pharmacol Exp Ther. , vol.277 , pp. 1049-1057
    • Laughlin, K.M.1    Evans, S.M.2    Jenkins, W.T.3
  • 66
    • 0028784382 scopus 로고
    • Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]
    • Evans SM, Joiner B, Jenkins WT, Laughlin KM, Lord EM, Koch CJ. Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]. Br J Cancer. 1995;72:875-882.
    • (1995) Br J Cancer , vol.72 , pp. 875-882
    • Evans, S.M.1    Joiner, B.2    Jenkins, W.T.3    Laughlin, K.M.4    Lord, E.M.5    Koch, C.J.6
  • 67
    • 0027376264 scopus 로고
    • Detection of hypoxic cells by monoclonal antibody recognizing 2-nitroimidazole adducts
    • Lord EM, Harwell L, Koch CJ. Detection of hypoxic cells by monoclonal antibody recognizing 2-nitroimidazole adducts. Cancer Res. 1993;53:5721-5726.
    • (1993) Cancer Res. , vol.53 , pp. 5721-5726
    • Lord, E.M.1    Harwell, L.2    Koch, C.J.3
  • 68
    • 0030838026 scopus 로고    scopus 로고
    • Hyperfixation of copper-62-PTSM in rat brain after transient global ischemia
    • Taniuchi H, Fujibayashi Y, Yonekura Y, Konishi J, Yokoyama A. Hyperfixation of copper-62-PTSM in rat brain after transient global ischemia. J Nucl Med. 1997;38:1130-1134.
    • (1997) J Nucl Med. , vol.38 , pp. 1130-1134
    • Taniuchi, H.1    Fujibayashi, Y.2    Yonekura, Y.3    Konishi, J.4    Yokoyama, A.5
  • 69
    • 0030811565 scopus 로고    scopus 로고
    • Copper-62-ATSM: A new hypoxia imaging agent with high membrane permeability and low redox potential
    • Fujibayashi Y, Taniuchi H, Yonekura Y, Ohtani H, Konishi J, Yokoyama A. Copper-62-ATSM: a new hypoxia imaging agent with high membrane permeability and low redox potential. J Nucl Med. 1997;38:1155-1160.
    • (1997) J Nucl Med. , vol.38 , pp. 1155-1160
    • Fujibayashi, Y.1    Taniuchi, H.2    Yonekura, Y.3    Ohtani, H.4    Konishi, J.5    Yokoyama, A.6
  • 70
    • 0002266827 scopus 로고    scopus 로고
    • Evaluation of copper-62 ATSM in patients with lung cancer as a hypoxic tissue tracer
    • Takahashi N, Fujibayashi Y, Yonekura Y, et al. Evaluation of copper-62 ATSM in patients with lung cancer as a hypoxic tissue tracer [abstract]. J Nucl Med. 1998;39:53P.
    • (1998) J Nucl Med. , vol.39
    • Takahashi, N.1    Fujibayashi, Y.2    Yonekura, Y.3
  • 71
    • 0006917036 scopus 로고    scopus 로고
    • Cu-ATSM, a new tumor agent predicting ability for bioreductive drug activation
    • Fujibayashi Y, Yoshimi E, Waki A, Takahashi N, Yonekura Y. Cu-ATSM, a new tumor agent predicting ability for bioreductive drug activation [abstract]. J Nucl Med. 1998;39:90P.
    • (1998) J Nucl Med. , vol.39
    • Fujibayashi, Y.1    Yoshimi, E.2    Waki, A.3    Takahashi, N.4    Yonekura, Y.5
  • 72
    • 0031869326 scopus 로고    scopus 로고
    • Design of hypoxia-targeting radiopharmaceuticals: Selective uptake of copper-64 complexes in hypoxic cells in vitro
    • Dearling JL, Lewis JS, Mullen GE, Rae MT, Zweit J, Blower PJ. Design of hypoxia-targeting radiopharmaceuticals: selective uptake of copper-64 complexes in hypoxic cells in vitro. Eur J Nucl Med. 1998;25:788-792.
    • (1998) Eur J Nucl Med. , vol.25 , pp. 788-792
    • Dearling, J.L.1    Lewis, J.S.2    Mullen, G.E.3    Rae, M.T.4    Zweit, J.5    Blower, P.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.