Treatment of leptomeningeal metastases in a rat model using a recombinant adenovirus containing the HSV-tk gene

Journal of Neurosurgery

Volumn 85, Issue 4, 1996, Pages 648-654

  Vincent, Arnaud J P E ^a   Esandi, Maria Del C ^b   Van Someren, Gerry ^b   Noteboom, Juus L ^b   Avezaat, Cees J J ^b   Vecht, Charles ^b   Sillevis Smitt, Peter A E ^b   Van Bekkum, Dirk W ^b   Valerio, Dinko ^b   Hoogerbrugge, Peter M ^b   Bout, Abraham ^b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b NONE

Author keywords

herpes simplex virus thymidine kinase gene; leptomeningeal metastases; rat; suicide gene therapy

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER MODEL; CONTROLLED STUDY; DRUG EFFICACY; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; INTRAPERITONEAL DRUG ADMINISTRATION; LEPTOMENINX; MALE; MENINGIOMA; METASTASIS; NONHUMAN; PRIORITY JOURNAL; RAT; VIRUS RECOMBINANT;

EID: 10144229106     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1996.85.4.0648     Document Type: Article

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