cDNA array analysis of cag pathogenicity island-associated Helicobacter pylori epithelial cell response genes

Infection and Immunity

Volumn 69, Issue 11, 2001, Pages 6970-6980

  Cox, J M ^a   Clayton, C L ^a   Tomita, T ^a   Wallace, D M ^a   Robinson, P A ^a   Crabtree, J E ^a  

^a ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM PROTEIN; AMPHIREGULIN; BACTERIAL DNA; CAG PATHOGENICITY ISLAND; COMPLEMENTARY DNA; DISINTEGRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; CYTOKINE RELEASE; DNA DETERMINATION; DNA HYBRIDIZATION; DNA RESPONSIVE ELEMENT; EPITHELIUM CELL; GENE EXPRESSION; HELICOBACTER PYLORI; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH EPITHELIUM;

ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; CELL LINE; DNA, BACTERIAL; DNA, COMPLEMENTARY; EPITHELIAL CELLS; GASTRIC MUCOSA; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENES, BACTERIAL; GLYCOPROTEINS; GROWTH SUBSTANCES; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KINETICS; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

EID: 0034773557     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.11.6970-6980.2001     Document Type: Article

References (81)

1. Mechanisms involved in Helicobacter pylori-induced interleukin-8 production by a gastric cancer cell line, MKN 45
2. Analyses of the cag pathogenicity island of Helicobacter pylori
3. Helicobacter pylori CagA protein can be tyrosine phosphorylated in gastric epithelial cells
4. Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by type IV secretion apparatus
5. An essential role for NF-κB in preventing TNF-alpha-induced cell death
6. ADAMS: Focus on the protease domain
7. Infection with Helicobacter pylori strains possessing cagA is associated with increased risk of developing adenocarcinoma of the stomach
8. A model of host microbial interactions in an open mammalian ecosystem
9. cag, a pathogenicity island of Helicobacter pylori, encodes type 1-specific and disease-associated virulence factors
10. Characterization of transformation related genes in oral cancer cells
11. Amphiregulin messenger RNA is elevated in psoriatic epidermis and gastrointestinal carcinomas
12. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer
13. + Helicobacter pylori strains
14. Helicobacter pylori infection, a paradigm for chronic mucosal inflammation: Pathogenesis and implications for eradication and therapy
15. Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration, and gastric pathology
16. Interleukin-8 expression in Helicobacter pylori infected, normal and neoplastic gastroduodenal mucosa
17. CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cells
18. Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype
19. Thymosin-β4 changes the conformation and dynamics of actin monomers
20. Expression profiling using cDNA microarrays
21. Analysis by high density cDNA arrays of altered gene expression in human intestinal epithelial cells in response to infection with invasive enteric bacteria Salmonella
22. Cluster analysis and display of genome-wide expression patterns
23. Non-coding, mRNA-like RNAs database Y2K
24. Human LINE retrotransposons generate processed pseugogenes
25. Host response to H. pylori: Molecular analysis of cytokine gene expression
26. A pancreatic cancer-specific expression profile
27. Bacterial adhesion and disease activity in Helicobacter associated chronic gastritis
28. Increased expression of IL-10 and IL-12 (p40) mRNA in Helicobacter pylori infected gastric mucosa: Relation to bacterial cag status and peptic ulceration
29. Interaction of Pseudomonas aeruginosa with epithelial cells: Identification of differentially regulated genes by expression microarray analysis of human cDNAs
30. Epithelial cells as sensors of microbial infection
31. Helicobacter pylori infection activates NF-κB in gastric epithelial cells
32. - Helicobacter pylori
33. Helicobacter pylori and atrophic gastritis: Importance of the cagA status
34. Multiple genes in the left half of the cag pathogenicity island of Helicobacter pylori are required for tyrosine kinase-dependent transcription of interleukin-8 in gastric epithelial cells
35. AAC-11 overexpression induces invasion and protects cervical cancer cells from apoptosis
36. Differential display of eukaryotic messenger RNA by means of polymerase chain reaction
37. Up-regulation of IL-17 is associated with bioactive IL-8 expression in Helicobacter pylori-infected human gastric mucosa
38. Thymosin β4 accelerates wound healing
39. Amino-acid transport by heterodimers of 4f2hc/CD98 and members of a permease family
40. The expression of the ADAMsp proteases in prostate cancer cell lines and their regulation by dihydrotestosterone
41. The metallo-disintegrin ADAM10 (MADM) from the bovine kidney has type IV collagenase activity in vitro
42. Serum ferritin, hemoglobin, and Helicobacter pylori infection: A seroepidemiologi survey comprising 2794 Danish adults
43. Regulation of nitric oxide production by arginine metabolic enzymes
44. Induction of epithelial apoptosis by Helicobacter pylori
45. A secreted/shed product of Helicobacter pylori activates transcription factor nuclear factor-κB
46. Localization of heparin-binding epidermal growth factorlike growth factor in human gastric mucosa
47. Matrix metalloproteinases and their inhibitors in gastric cancer
48. Activation of activator protein 1 and stress response kinases in epithelial cells colonized by Helicobacter pylori encoding the cag pathogenicity island
49. Prokaryotic regulation of epithelial responses by inhibition of IκB-alpha ubiquinitination
50. Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion
51. Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection
52. Heightened inflammatory response to cytokine expression in vivo to CagA+ Helicobacter pylori strains
53. Helicobacter pylori cagA+ strains and dissociation of gastric epithelial cell proliferation and apoptosis
54. A model for p53-induced apoptosis
55. Antioxidant inducible genes
56. Helicobacter pylori upregulates expression of epidermal growth factorrelated peptides, but inhibits their proliferative effect in MKN28 gastric mucosal cells
57. Identification and characterization of a Pro-tumour necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases
58. Elongin BC complex prevents degradation of von Hippel-Lindau tumour suppressor gene products
59. Altered states: Involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori
60. Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro
61. Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-κB in gastric epithelial cells
62. Chemokine mRNA expression in gastric mucosa is associated with Helicobacter pylori cagA positivity and severity of gastritis
63. CagA seropositivity associated with the development of gastric cancer in a Japanese population
64. A simple subtractive hybridization technique employing photoactivatable biotin and phenol extraction
65. Automated differential display using a fluorescently labeled universal primer
66. Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation
67. + Helicobacter pylori strains as a possible predictor of risk in the development of gastric adenocarcinoma in Mexico
68. Expression and activation of NF-κB in the antrum of the human stomach
69. Serial analysis of gene expression
70. Helicobacter pylori and the pathogenesis of duodenal ulceration
71. Gastric cancer, cytotoxinassociated gene A positive Helicobacter pylori, and serum pepsinogens: An international study
72. The interrelationship between cytotoxin-associated gene A, vacuolating cytotoxin, and Helicobacter pylori-related disease
73. Expression of members of the novel membrane linked metalloprotease family ADAM in cells derived from a range of haematological malignancies
74. IEX-1L, an apoptosis inhibitor involved in NF-κB cell survival
75. ADAM family proteins in the immune system
76. Helicobacter pylori cagA gene and expression of cytokine messenger RNA in gastric mucosa
77. Chemokines in the gastric mucosa in Helicobacter pylori infection
78. Helicobacter pylori increases gastric ADAM 10 and ADAM 17 mRNA expression
79. Thymosin β4 sulfoxide is an anti-inflammatory agent generated by monocytes in the presence of glucocorticoids
80. The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation
81. Sequencing and expression of complementary DNA for the general transcription factor BTF3