Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection

Gut

Volumn 40, Issue 3, 1997, Pages 297-301

  Parsonnet, J ^a,c   Friedman, G D ^b   Orentreich, N ^d   Vogelman, H ^d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DIVISION OF RESEARCH   (United States)

^c STANFORD UNIVERSITY   (United States)

^d NONE

Author keywords

ABO blood group; CagA; cigarette smoking; gastric neoplasm; Helicobacter pylori; pepsinogen

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; PEPSINOGEN;

ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTRITIS; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; RISK FACTOR; STOMACH CANCER;

EID: 0030975595     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.40.3.297     Document Type: Article

References (33)

1. Parsonnet J, Friedman GD, Vandersteen DP, et al. Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 1991; 325: 1127-31.
2. Nomura AMY, Stemmerman GN, Chyou P, Kato I, Perez-Perez GI, Blaser MJ. Helicobacter pylori infection and gastric carcinoma in a population of Japanese-Americans in Hawaii. N Engl J Med 1991; 325: 1132-6.
3. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Helicobacter pylori. In: Schistosomes, liver flukes, and Helicobacter pylori: views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon: IARC, 1994: 177-240.
4. Nomura AM, Stemmermann GN, Chyou PH. Gastric cancer among the Japanese in Hawaii. Jpn J Cancer Res 1995; 86: 916-23.
5. Kneller RW, You WC, Chang YS, et al. Cigarette smoking and other risk factors for progression of precancerous stomach lesions. J Natl Cancer Inst 1992; 84: 1261-6.
6. Hansson LE, Baron J, Nyren O, Bergstrom R, Wolk A, Adami HO. Tobacco, alcohol, and the risk of gastric cancer. A population-based case-control study in Sweden. Int J Cancer 1994; 57: 26-31.
7. Howson C, Hiyama T, Wynder E. The decline in gastric cancer: epidemiology of an unplanned triumph. Epidemiol Rev 1986; 8: 1-27.
8. Boren T, Falk P, Roth KA, Larson G, Normack S. Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens. Science 1993; 262: 1892-5.
9. Mentis A, Blackwell CC, Weir DM, Spiliadis C, Dailianas A, Skandalis N. ABO blood group, secretor status and detection of Helicobacter pylori among patients with gastric or duodenal ulcers. Epidemiol Infect 1991; 106: 221-9.
10. Cover TL, Tummuru MK, Cao P, Thompson SA, Blaser MJ. Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains. J Biol Chem 1994; 269: 10566-73.
11. Takami S, Hayashi T, Tonokatsu Y, Shimoyama T, TamuraT. Chromosomal heterogeneity of Helicobacter pylori isolates by pulsed-field gel electrophoresis. Int J Med Microbiol Virol Parasitol Infect Dis 1993; 280: 102-7.
12. Desai M, Linton D, Owen RJ, Cameron H, Stanley J. Genetic diversity of Helicobacter pylori indexed with respect to clinical symptomatology, using a 16S rRNA and a species-specific DNA probe. J Appl Bacteriol 1993; 75: 574-82.
13. Taylor DE, Eaton M, Chang N, Salama SM. Construction of a Helicobacter pylori genome map and demonstration of diversity at the genome level. J Bacteriol 1992; 174: 6800-6.
14. Telford JL, Covacci A, Ghiara P, Montecucco C, Rappuoli R. Unravelling the pathogenic role of Helicobacter pylori in peptic ulcer: potential new therapies and vaccines. Trends Biotechnol 1994; 12: 420-6.
15. Xiang Z, Censini S, Bayeli PF, et al. Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin. Infect Immun 1995; 63: 94-8.
16. Crabtree JE, Covacci A, Farmery SM, et al. Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype. J Clin Pathol 1995; 48: 41-5.
17. Cover TL, Glupczynski Y, Lage AP, et al. Serologic detection of infection with cagA+ Helicobacter pylori strains. J Clin Microbiol 1995; 33: 1496-500.
18. Crabtree JE, Taylor JD, Wyatt JI, et al. Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration, and gastric pathology. Lancet 1991; 338: 332-5.
19. Peek RM, Miller GG, Tham KT, et al. Heightened inflammatory response and cytokine expression in vivo to cagA+ Helicobacter pylori strains. Lab Invest 1995; 73: 760-70.
20. Blaser MJ. Intrastrain differences in Helicobacter pylori: a key question in mucosal damage? Ann Med 1995; 27: 559-63.
21. Kuipers EJ, Perez-Perez GI, Meuwissen SG, Blaser MJ, Helicobacter pylori and atrophic gastritis: importance of the cagA status. J Natl Cancer Inst 1995; 87: 1777-80.
22. Blaser MJ, Perez-Perez GI, Kleanthous H, et al. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995; 55: 2111-5.
23. Parsonnet J, Samloff IM, Nelson LM, Orentreich N, Vogelman JH, Friedman GD. Helicobacter pylori, pepsinogen and risk for gastric adenocarcinoma. Cancer Epidemiol Biomarkers Prev 1993; 2: 1-7.
24. Borch K, Axelsson K, Halgreen H, Damkjaer Nielsen MD, Ledin T, Szesci PB. The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis. Scand J Gastroenterol 1989; 24: 870-6.
25. Kekki M, Samloff IM, Varis K, Ihamaki T. Serum pepsinogen I and serum gastrin in the screening of severe atrophic gastritis. Scand J Gastroenterol Suppl 1991; 186: 109-16.
26. Huang J, O'Toole PW, Doig P, Trust TJ. Stimulation of interleukin-8 production in epithelial cell lines by Helicobacter pylori. Infect Immun 1995; 63: 1732-8.
27. Sharma SA, Tummuru MK, Miller GG, Blaser MJ. Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro. Infect Immun 1995; 63: 1681-7.
28. Blaser MJ. Helicobacter pylori phenotypes associated with peptic ulceration. Scand J Gastroenterol Suppl 1994; 205: 1-5.
29. Fox JG, Correa P, Taylor NS, et al. High prevalence and persistence of cytotoxin-positive Helicobacter pylori strains in a population with high prevalence of atrophic gastritis. Am J Gastroenterol 1992; 87: 1554-60.
30. Atherton JC, Cao P, Peek RM, Tummuru MK, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem 1995; 270: 17771-7.
31. Xiang Z, Censini S, Bayeli PF, et al. Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin. Infect Immun 1995; 63: 94-8.
32. Fauconnier A, Burette A, Goutier S, Butzler JP, Bollen A, Glupczynski Y. Frequency of cagA in Helicobacter pylori strains isolated from Belgian and Moroccan patients [abstract]. Gut 1995; 37: A69.
33. Parsonnet J, Replogle ML, Yang S, Hiatt RA. Prevalence of the type 1 H. pylori phenotype differs among ethnic/racial groups in the San Francisco Bay area. J Infect Dis (in press).