A scintillation proximity assay for the raf/MEK/ERK kinase cascade: High-throughput screening and identification of selective enzyme inhibitors

Analytical Biochemistry

Volumn 268, Issue 2, 1999, Pages 318-329

  McDonald, Octerloney B ^a   Chen, Wen Ji ^a   Ellis, Byron ^a   Hoffman, Christine ^a   Overton, Laurie ^a   Rink, Martin ^a   Smith, Albert ^a   Marshall, Christopher J ^b   Wood, Edgar R ^a  

^a GLAXOSMITHKLINE   (United States)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI; PEPTIDES; SCINTILLATION; SIGNAL TRANSDUCTION;

ENZYME INHIBITORS; FUSION PROTEINS; GLUTATHIONE S-TRANSFERASES; HIGH THROUGHPUT SCREENING; HIS-TAGGED PROTEINS; KINASE CASCADE; PEPTIDE SUBSTRATES; SIGNAL TRANSDUCTION PATHWAYS;

ENZYMES;

ADENOSINE TRIPHOSPHATE; COMPLEMENTARY DNA; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; BACULOVIRUS; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; ENZYME SUBSTRATE; ESCHERICHIA COLI; GENE EXPRESSION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ESCHERICHIA COLI; INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 0344177511     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.1998.3030     Document Type: Article

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