Antitumor agents. 199. Three-dimensional quantitative structure-activity relationship study of the colchicine binding site ligands using comparative molecular field analysis

Journal of Medicinal Chemistry

Volumn 43, Issue 2, 2000, Pages 167-176

  Zhang, Shun Xiang ^a   Feng, Jun ^a   Kuo, Sheng Chu ^b   Brossi, Arnold ^a   Hamel, Ernest ^c   Tropsha, Alexander ^a   Lee, Kuo Hsiung ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; COLCHICINE; COLCHICINE DERIVATIVE; FLAVONOID; PROTEIN INHIBITOR; TUBULIN;

ARTICLE; BINDING SITE; DRUG BINDING; DRUG STRUCTURE; MICROTUBULE; MOLECULAR MODEL; PROTEIN POLYMERIZATION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REACTION ANALYSIS;

ANTINEOPLASTIC AGENTS; COLCHICINE; ELECTROSTATICS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034719321     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990333a     Document Type: Article

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