Antitumor Agents-CLXXV. Anti-tubulin action of (+)-thiocolchicine prepared by partial synthesis

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 12, 1997, Pages 2277-2282

  Shi, Qian ^a   Verdier Pinard, Pascal ^b   Brossi, Arnold ^a   Hamel, Ernest ^b   Lee, Kuo Hsiung ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Antitubulin; Antitumor; Colchicine; Enantiomer; Thiocolchicine

Indexed keywords

COLCHICINE DERIVATIVE; THIOCOLCHICINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BURKITT LYMPHOMA; DIASTEREOISOMER; ENANTIOMER; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTIAL DRUG SYNTHESIS; STEREOCHEMISTRY;

ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, THIN LAYER; COLCHICINE; HUMANS; ISOMERISM; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; TUBULIN MODULATORS; TUMOR CELLS, CULTURED;

EID: 0031436518     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00171-5     Document Type: Article

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