Antitumor agents. 181. Synthesis and biological evaluation of 6,7,2',3',4'-substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a new class of antimitotic antitumor agents

Journal of Medicinal Chemistry

Volumn 41, Issue 7, 1998, Pages 1155-1162

  Xia, Yi ^a   Yang, Zheng Yu ^a   Xia, Peng ^a   Bastow, Kenneth F ^a   Tachibana, Yoko ^a   Kuo, Sheng Chu ^b   Hamel, Ernest ^c   Hackl, Torben ^c   Lee, Kuo Hsiung ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; COLCHICINE; COMBRETASTATIN; PODOPHYLLOTOXIN; QUINOLONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CYTOTOXICITY; DRUG SYNTHESIS; ENANTIOMER; KIDNEY CANCER; LUNG CANCER; NASOPHARYNX CANCER; RACEMIC MIXTURE;

ANTIBIOTICS, ANTINEOPLASTIC; HUMANS; QUINOLONES; TUBULIN; TUMOR CELLS, CULTURED;

EID: 0032568390     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9707479     Document Type: Article

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