Investigating protein-ligand interactions with a mutant FKBP possessing a designed specificity pocket

Journal of Medicinal Chemistry

Volumn 43, Issue 6, 2000, Pages 1135-1142

  Yang, Wu ^a   Rozamus, Leonard W ^a   Narula, Surinder ^a   Rollins, Carl T ^a   Yuan, Ruth ^a   Andrade, Lawrence J ^a   Ram, Mary K ^a   Phillips, Thomas B ^a   Van Schravendijk, Marie Rose ^a   Dalgarno, David ^a   Clackson, Tim ^a   Holt, Dennis A ^a  

^a ARIAD PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN;

ARTICLE; DIMERIZATION; DNA BINDING; HYDROPHOBICITY; LIGAND BINDING; MUTAGENESIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY; RECEPTOR OCCUPANCY; STRUCTURE ANALYSIS; TARGET CELL;

ACETAMIDES; BENZENE DERIVATIVES; IMMUNOPHILINS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MUTATION; PROTEIN ENGINEERING; STRUCTURE-ACTIVITY RELATIONSHIP; TACROLIMUS BINDING PROTEINS;

EID: 0034704881     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9904396     Document Type: Article

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