A Modular DNA Carrier Protein Based on the Structure of Diphtheria Toxin Mediates Target Cell-specific Gene Delivery

Journal of Biological Chemistry

Volumn 273, Issue 15, 1998, Pages 8835-8841

  Uherek, Christoph ^a   Fominaya, Jesús ^b   Wels, Winfried ^a  

^a TUMOR BIOLOGY CENTER   (Germany)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM CHLORIDE; BAFILOMYCIN A1; CARRIER PROTEIN; CHLOROQUINE; DIPHTHERIA TOXIN; DNA FRAGMENT; HYBRID PROTEIN; METHYLAMINE; NIGERICIN;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL SPECIFICITY; CONTROLLED STUDY; DNA BINDING; ESCHERICHIA COLI; GENE THERAPY; GENE TRANSFER; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REPORTER GENE; TOXIN ANALYSIS;

AMMONIUM CHLORIDE; ANIMALS; ANTI-BACTERIAL AGENTS; BREAST NEOPLASMS; CHLOROQUINE; COS CELLS; DIPHTHERIA TOXIN; FEMALE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; MACROLIDES; METHYLAMINES; NIGERICIN; RECEPTOR, ERBB-2; RECOMBINANT FUSION PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0032502668     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.15.8835     Document Type: Article

References (46)

1. Schnierle, B. S., and Groner, B. (1996) Gene Ther. 3, 1069-1073
2. Cooper, M. J. (1996) Semin. Oncol. 23, 172-187
3. Wu, G. Y., and Wu, C. H. (1987) J. Biol. Chem. 262, 4429-4432
4. Wagner, E., Cotten, M., Foisner, R., and Birnstiel, M. L. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 4255-4259
5. Perales, J. C., Ferkol, T., Molas, M., and Hanson, R. W. (1994) Eur. J. Biochem. 226, 255-266
6. Felgner, P. L., Barenholz, Y., Behr, J. P., Cheng, S. H., Cullis, P., Huang, L., Jessee, J. A., Seymour, L., Szoka, F., Thierry, A. R., Wagner, E., and Wu, G. (1997) Hum. Gene Ther. 8, 511-512
7. Curiel, D. T., Agarwal, S., Wagner, E., and Cotten, M. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 8850-8854
8. Wagner, E., Plank, C., Zatloukal, K., Cotten, M., and Birnstiel, M. L. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 7934-7938
9. Olsnes, S., van Deurs, B., and Sandvig, K. (1993) Med. Microbiol. Immunol. 182, 51-61
10. Donnelly, J. J., Ulmer, J. B., Hawe, L. A., Fríedman, A., Shi, X. P., Leander, K. R., Shiver, J. W., Oliff, A. I., Martinez, D., Montgomery, D., and Liu, M. A. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 3530-3534
11. Novoa, I., Cotten, M., and Carrasco, L. (1996) J. Virol. 70, 3319-3324
12. Fominaya, J., and Wels, W. (1996) J. Biol. Chem. 271, 10560-10568
13. Greenfield, L., Bjorn, M. J., Horn, G., Fong, D., Buck, G. A., Collier, R. J., and Kaplan, D. A. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 6853-6857
14. Choe, S., Bennett, M. J., Fujii, G., Curmi, P. M., Kantardjieff, K. A., Collier, R. J., and Eisenberg, D. (1992) Nature 357, 216-222
15. Carey, M., Kakidani, H., Leatherwood, J., Mostashari, F., and Ptashne, M. (1989) J. Mol. Biol. 209, 423-432
16. Hynes, N. E., and Stern, D. F. (1994) Biochim. Biophys. Acta 1198, 165-184
17. Wels, W., Groner, B., and Hynes, N. E. (1996) Curr. Top. Microbiol. Immunol. 213, 113-128
18. Hynes, N. E., Taverna, D., Harwerth, I. M., Ciardiello, F., Salomon, D. S., Yamamoto, T., and Groner, B. (1990) Mol. Cell. Biol. 10, 4027-4034
19. vanderSpek, J. C., Mindell, J. A., Finkelstein, A., and Murphy, J. R. (1993) J. Biol. Chem. 268, 12077-12082
20. Wels, W., Beerli, R., Hellmann, P., Schmidt, M., Marte, B. M., Kornilova, E. S., Hekele, A., Mendelsohn, J., Groner, B., and Hynes, N. E. (1995) Int. J. Cancer 60, 137-144
21. Proba, K., Ge, L., and Plückthun, A. (1995) Gene (Amst.) 159, 203-207
22. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
23. Wels, W., Harwerth, I. M., Zwickl, M., Hardman, N., Groner, B., and Hynes, N. E. (1992) Bio/Technology 10, 1128-1132
24. Fominaya, J., Uherek, C., and Wels, W. (1998) Gene Ther. 5, 521-530
25. Harwerth, I. M., Wels, W., Marte, B. M., and Hynes, N. E. (1992) J. Biol. Chem. 267, 15160-15167
26. Mellman, I., Fuchs, R., and Helenius, A. (1986) Annu. Rev. Biochem. 55, 663-700
27. Zenke, M., Steinlein, P., Wagner, E., Cotten, M., Beug, H., and Birnstiel, M. L. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 3655-3659
28. Cotten, M., Langle-Rouault, F., Kirlappos, H., Wagner, E., Mechtler, K., Zenke, M., Beug, H., and Birnstiel, M. L. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 4033-4037
29. Fritz, J. D., Herweijer, H., Zhang, G., and Wolff, J. A. (1996) Hum. Gene Ther. 7, 1395-1404
30. Wagner, E., Curiel, D., and Cotten, M. (1994) Adv. Drug Delivery Rev. 14, 113-135
31. Naglich, J. G., Metherall, J. E., Russell, D. W., and Eidels, L. (1992) Cell 69, 1051-1061
32. Sandvig, K., and Olsnes, S. (1981) J. Biol. Chem. 256, 9068-9076
33. vanderSpek, J., Cassidy, D., Genbauffe, F., Huynh, P. D., and Murphy, J. R. (1994) J. Biol. Chem. 269, 21455-21459
34. Umata, T., Moriyama, Y., Futai, M., and Mekada, E. (1990) J. Biol. Chem. 265, 21940-21945
35. Bowman, E. J., Siebers, A., and Altendorf, K. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 7972-7976
36. Chen, S. Y., Zani, C., Khouri, Y., and Marasco, W. A. (1995) Gene Ther. 2, 116-123
37. Paul, R. W., Weisser, K. E., Loomis, A., Sloane, D. L., LaFoe, D., Atkinson, E. M., and Overell, R. W. (1997) Hum. Gene Ther. 8, 1253-1262
38. Wels, W., and Fominaya, J. (1998) in Self-assembling Complexes for Gene Delivery: From Laboratory to Clinical Trial (Kabanov, A. V., Felgner, P., and Seymour, L. W., eds) pp. 351-369, John Wiley & Sons Ltd., Chichester, England
39. Nelson, M., and Silver, P. (1989) Mol. Cell. Biol. 9, 384-389
40. London, E. (1992) Biochim. Biophys. Acta 1113, 25-51
41. Kagan, B. L., Finkelstein, A., and Colombini, M. (1981) Proc. Natl. Acad. Sci. U. S. A. 78, 4950-4954
42. O'Keefe, D. O., Cabiaux, V., Choe, S., Eisenberg, D., and Collier, R. J. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 6202-6206
43. Madshus, I. H., Wiedlocha, A., and Sandvig, K. (1994) J. Biol. Chem. 269, 4648-4652
44. Hoch, D. H., Romero-Mira, M., Ehrlich, B. E., Finkelstein, A., DasGupta, B. R., and Simpson, L. L. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 1692-1696
45. Jiang, G. S., Solow, R., and Hu, V. W. (1989) J. Biol. Chem. 264, 13424-13429
46. Fisher, K. J., and Wilson, J. M. (1997) Biochem. J. 321, 49-58