Quantitative analysis of protein synthesis inhibition and recovery in CRM107 immunotoxin-treated HeLa cells

Biotechnology and Bioengineering

Volumn 57, Issue 4, 1998, Pages 484-496

  Wenning, Larissa A ^a   Yazdi, Parvin T ^b   Murphy, Regina M ^a  

^a University of Wisconsin Madison   (United States)

^b Clarion Pharmaceuticals   (United States)

Author keywords

Cellular trafficking; CRM107; Diphtheria toxin; Immunotoxins; Transferrin receptor

Indexed keywords

BIODEGRADATION; BIOSYNTHESIS; CELLS; MATHEMATICAL MODELS; MONOCLONAL ANTIBODIES; REACTION KINETICS;

IMMUNOTOXINS; PROTEIN SYNTHESIS INHIBITION;

DRUG INTERACTIONS;

DIPHTHERIA TOXIN; IMMUNOTOXIN; MONOCLONAL ANTIBODY;

ARTICLE; CELL KILLING; CONCENTRATION RESPONSE; DEGRADATION; HELA CELL; INHIBITION KINETICS; MATHEMATICAL MODEL; PROTEIN SYNTHESIS INHIBITION;

ANTIBODIES, MONOCLONAL; BIOLOGICAL TRANSPORT; CELL DIVISION; CYTOSOL; DIPHTHERIA TOXIN; HELA CELLS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOTOXINS; KINETICS; MATHEMATICS; MODELS, BIOLOGICAL; PROTEIN BIOSYNTHESIS; PROTEIN SYNTHESIS INHIBITORS; PROTEINS; TRANSFERRIN;

EID: 0032549106     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19980220)57:4<484::AID-BIT13>3.0.CO;2-C     Document Type: Article

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