Enhanced gene delivery and expression in human hepatocellular carcinoma cells by cationic immunoliposomes

Journal of Liposome Research

Volumn 7, Issue 1, 1997, Pages 127-141

  Compagnon, Béatrice ^a   Moradpour, Darius ^a   Alford, Dennis R ^a   Larsen, Charles E ^a   Stevenson, Michael J ^a   Mohr, Leonhard ^a   Wands, Jack R ^a   Nicolau, Claude ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG CARRIER; DRUG VEHICLE; IMMUNOLIPOSOME; MONOCLONAL ANTIBODY;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; EXPRESSION VECTOR; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER CARCINOMA; PRIORITY JOURNAL;

EID: 0031041393     PISSN: 08982104     EISSN: None     Source Type: Journal    
DOI: 10.3109/08982109709035490     Document Type: Article

References (27)

1. Nicolau, C., Le Pape, A., Soriano, P., Fargette, F. and Juhel, M.-F. 1983. In vivo expression of rat insulin after intravenous administration of the liposome-entrapped gene for rat insulin I. Proc. Natl. Acad. Sci. U.S.A. 80:1068-1072.
2. Soriano, P., Dijkstra, J., Legrand, A., Spanjer, H., Londos-Gagliardi, D., Roerdink, F., Scherphof, G. and Nicolau, C. 1983 Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene. Proc. Natl. Acad. Sci. U.S.A. 80: 7128-7131.
3. Felgner, P.L., Gadek, T.R., Holm, M., Roman, R., Chan, H.W., Wenz, M., Northrop, J.P., Ringold, G.M. and Danielsen, M. 1987. Lipofectin: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl. Acad. Sci. U.S.A. 84: 7413-7417.
4. Nabel, E.G., Plautz, G. and Nabel, G.J. 1990. Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science 249: 1285-1288.
5. Zhu, N., Liggitt, D., Liu, Y. and Debs, R. 1993. Systemic gene expression after intravenous DNA delivery into adult mice. Science 261: 209-211.
6. Caplen, N.J., Alton, E.W.F.W., Middleton, P.G., Dorin, J.R., Stevenson, B.J., Gao, X., Durham, S.R., Jeffery, P.K., Hodson, M.E., Coutelle, C., Huang, L., Porteous, D.J., Williamson, R. and Geddes, D.M. 1995 Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nature Med. 1: 39-46.
7. Thierry, A.R., Lunardi-Iskandar, Y., Bryant, J.L., Rabinovich, P., Gallo, R.C. and Mahan, L.C. 1995. Systemic gene therapy: biodistribution and long-term expression of a transgene in mice. Proc. Natl. Acad. Sci. U.S.A. 92: 9742-9746.
8. Düzgünes, N., Goldstein, J.A., Friend, D.S. and Felgner, P.L. 1989. Fusion or liposomes containing a novel cationic lipid, N-[2,3-(dioleyloxy)propyl]-N,N,N-trimethylammonium: induction by multivalent anions and asymmetric fusion with acidic phospholipid vesicles. Biochemistry 28: 9179-9184.
9. Felgner, J.H., Kumar, R., Sridhar, C.N., Wheeler C.J., Tsai, Y.J., Border, R., Ramsey, P., Martin, M. and Felgner, P.L. 1994. Enhanc ed gene delivery and mechanism studies with a novel series of cationic lipid formulations. J. Biol. Chem. 269: 2550-2561.
10. Hara, T., Aramaki, Y., Takada, S., Koike, K. and Tsuchiya, S. 1995. Receptor-mediated transfer of pSV2CAT DNA to mouse liver cells using asialofetuin-labeled liposomes. Gene Therapy 2: 784-788.
11. Wu, G. and Wu, C. 1986. Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. J. Biol. Chem. 262: 4429-4432.
12. Midoux, P., Mendes, C., Legrand, A., Raimond, J., Mayer, R., Monsigny, M. and Roche, A.C. 1993. Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells. Nucleic Acids Res. 21: 871-878.
13. Trubetskoy, V.S., Torchilin, V.P., Kennel, S. and Huang, L. 1992. Cationic liposomes enhance targeted delivery and expression of exogenous DNA mediated by N-terminal modified poly(L-lysine)-antibody conjugate in mouse lung endothelial cells. Biochim. Biophys. Acta 1131: 311-313.
14. Remy, J.-S., Kichler, A., Mordvinov, V., Schuber, F. and Behr J.-P. 1995. Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses. Proc. Natl. Acad. Sci. U.S.A. 92: 1744-1748.
15. Kasahara, N., Dozy, A.M. and Kan, Y.W. 1994. Tissue-specific targeting of retroviral vectors through ligand-receptor interactions. Science 266: 1373-1376.
16. Wilson, B., Ozturk, M., Takahashi, H., Motté, P., Kew, M., Isselbacher, K.J. and Wands, J.R. 1988. Cell-surface changes associated with transformation of human hepatocytes to the malignant phenotype. Proc. Natl. Acad. Sci. U.S.A. 85: 3140-3144.
17. Takahashi, H., Ozturk, M., Wilson, B., Maki, A., Ozawa, K., Koizumi, M., Endo, K., Strauss, W., Shouval, D. and Wands, J. 1989. In vivo expression of two novel tumor-associated antigens and their use in immunolocalization of human hepatocellular carcinoma. Hepatology 9: 625-634.
18. Moradpour, D., Compagnon, B., Nicolau, C. and Wands, J.R. 1995. Specific targeting of human hepatocellular carcinoma cells by immunoliposomes in vitro. Hepatology 22: 1527-1537.
19. Sambrook, J., Fritsch, E.F. and Maniatis, T. 1989. Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
20. Szoka, F., Olson, F., Heath, T., Vail, W., Mayhew, E. and Papahadjopoulos, D. 1980. Preparation of unilamellar liposomes of intermediate size (0.1 - 0.2 μm) by a combination of reverse phase evaporation and extrusion through polycarbonate membranes. Biochim. Biophys. Acta 601: 559-571.
21. Düzgüneş, N., Wilschut, J., Hong, K., Fraley, R., Perry, C., Friend, D.S., James, T.L. and Papahadjopoulos, D. 1983. Physicochemical characterization of large unilamellar vesicles prepared by reverse-phase evaporation. Biochim. Biophys. Acta 732: 289-299.
22. Bartlett, G.R. 1959. Phosphorus assay in column chromatography. J. Biol. Chem. 234: 466-468.
23. Brasier, A.R. 1990. Reporter system using firefly luciferase. In "Current Protocols in Molecular Biology." F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith and K. Struhl (Eds.). John Wiley & Sons, New York, pp. 9.6.10-9.6.14.
24. Gao, X. and Huang, L. 1995. Cationic liposome-mediated gene transfer. Gene Therapy 2: 710-722.
25. Wagner, R.W. 1994. Gene inhibition using antisense oligodeoxy-nucleotides. Nature 372: 333-335.
26. Grebenkämper, K. and Nicolau, C. 1995. Signal transduction in Sf9 insect cells: endocytosis of recombinant CD4 after phorbol ester treatment. Biochem. Biophys. Res. Commun. 207: 411-416.
27. Moolten, F.L. 1994. Drug sensitivity (suicide) genes for selective cancer chemotherapy. Cancer Gene Therapy 1: 279-287.