Localization of granzyme B in the nucleus: A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis

Journal of Biological Chemistry

Volumn 271, Issue 8, 1996, Pages 4127-4133

  Trapani, Joseph A ^a   Browne, Kylie A ^a   Smyth, Mark J ^a   Jans, David A ^b  

^a AUSTIN RESEARCH INSTITUTE   (Australia)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ENZYME;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CELL NUCLEUS; CYTOTOXICITY, IMMUNOLOGIC; GRANZYMES; HL-60 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; KILLER CELLS, NATURAL; KINETICS; LEUKEMIA; LEUKEMIA, BASOPHILIC, ACUTE; RATS; SERINE ENDOPEPTIDASES; T-LYMPHOCYTES, CYTOTOXIC; TUMOR CELLS, CULTURED;

EID: 0030044052     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.8.4127     Document Type: Article

References (60)

1. Rouvier, E , Luciani, M. F , and Golstein, P (1993) J Exp. Med 177, 195-200
2. Yonehara, S., Ishii, A , and Yonehara, K. (1989) J. Exp Med 169, 1747-1756
3. Young, J. D -E, and Cohn, Z. A. (1986) Cell 46, 641-656
4. Henkart, P. A. (1985) Annu. Rev Immunol 3, 31-58
5. Smyth, M. J , and Trapani, J. A. (1995) Immunol Today 16, 202-206
6. Kagi, D , Ledermann, B., Burki, K., Seiler, P., Odermatt, B., Olsen, K. J., Podack, E. R., Zinkernagel, R. M., and Hengartner, H (1994) Nature 369, 31-37
7. Watanabe-Fukunaga, R., Brannan, C. I., Itoh, N., Yonehara, S., Copeland, N. G., Jenkins, N A., and Nagata, S. (1994) Nature 356, 314-317
8. Liu, C.-C., Perussia, B., Cohn, Z. A., and Young, J D.-E (1986) J Exp. Med. 164, 2061-2076
9. Duke, R. C., Persechini, P. M , Chang, S., Liu, C.-C., Cohen, J. J , and Young, J. D.-E (1989) J. Exp Med. 170, 145-161
10. Duke, R C., Sellins, K S., and Cohen, J. J (1988) J Immunol. 141, 2191-2194
11. Hudig, D., Allison, N. J., Pickett, T. M , Winkler, U., Kam, C , and Powers, J C. (1991) J Immunol. 147, 1360-1368
12. Chang, T W., and Eisen, H. (1980) J. Immunol 124, 870-878
13. Shi, L , Kraut, R P., Aebersold, R., and Greenberg, A H. (1991) J. Exp Med 175, 553-566
14. Shi, L., Nishioka, W. K., Th'ng, J., Bradbury, E. M , Litchfield, D W , and Greenberg, A. H. (1994) Science 243, 1443-1445
15. Forsburg, R. S., and Nurse, P (1991) Annu Rev. Cell Biol. 7, 227-256
16. Trapani, J. A , Smyth, M. J , Apostolidis, V A., Dawson, M., and Browne, K. A (1994) J. Biol. Chem. 269, 18359-18365
17. Yurt, R. W., Leid, R. W., Jr, Austen, K. F , and Silbert, J. E (1979) J. Biol. Chem. 252, 518-521
18. Trapani, J A., Browne, K. A., Dawson, M., and Smyth, M. J (1993) Biochem. Biophys. Res. Commun. 158, 910-920
19. Geisberg, M., Trapani, J. A., and Dupont, B. (1991) Tissue Antigens 35, 229-235
20. Northemann, W., Heisig, M , Kunz, D , and Heinrich, P. C. (1985) J Biol. Chem. 260, 6200-6205
21. Green, G D , and Shaw, E. (1979) Anal Biochem. 93, 223-226
22. Smyth, M. J, Wiltrout, T, Trapam, J. A., Ottaway, K S., Sowder, R., Henderson, L. E., Kam, C., Powers, J. C., Young, H. A., and Sayers, T. J (1992) J. Biol. Chem. 267, 24418-24425
23. Jans, D. A., Ackermann, M., Bischoff, J. R , Beach, D. H., and Peters, R. (1991) J Cell Biol 115, 1203-1210
24. Rihs, H -P , Jans, D A , Fan, H , and Peters, R. (1991) EMBO J 10, 633-639
25. Jans, D. A., and Jans, P. (1994) Oncogene 9, 2961-2970
26. Jans, D. A., Moll, T., Nasmyth, K., and Jans, P. (1995) J Biol. Chem., in press
27. Jans, D. A. (1995) Biochem. J , in press
28. Warren, G. (1987) Nature. 327, 17
29. McNeil, H. P., Austen, K F., Somerville, L. L., Gurish, M. F., and Stevens, R. L. (1991) J Biol Chem. 266, 20316-20322
30. Sali, A., Matsumoto, R., McNeil, H. P , Karplus, M., and Stevens, R. L (1993) J. Biol. Chem. 268, 9023-9034
31. Huang, R , Blom, T., and Hellman, L (1991) Eur. J. Immunol. 21, 1611-1621
32. Trapani, J. A , Klein, J., White, P. C , and Dupont, B. (1988) Proc. Natl. Acad. Sci. U. S A. 85, 6924-6928
33. Ojcius, D. M., Zheng, L. M , Sphicas, E. C., Zyehlinsky, A , and Young, J. D.-E. (1991) J. Immunol. 146, 4427-4432
34. Burkhardt, J. K., Hester, S , Lapham, C K., and Argon, Y. (1990) J. Cell Biol. 111, 2327-2434
35. Liu, C.-C., Rafii, S., Granelli-Piperno, A , Trapani, J. A., and Young, J. D.-E. (1989) J. Exp Med. 170, 2105-2118
36. Podack, E. R. (1985) Immunol. Today 6, 21-26
37. Nakajima, H., and Henkart, P. A. (1994) J. Immunol. 152, 1057-1063
38. Feilotter, H , Lingner, C., Rowley, R., and Young, P. G. (1992) Biochem. Cell Biol. 70, 954-971
39. Griffiths, G. M., and Isaaz, S. (1993) J. Cell Biol. 120, 885-891
40. Borer, R. A., Lehner, C. F., Eppenberger, H. M., and Nigg, E. A. (1989) Cell 56, 379-390
41. Jans, D. A. (1995) Science Int., in press
42. Garcia-Bustos, J , Heitman, J., and Hall, M. N. (1991) Biochim. Biophys. Acta 1071, 83-93
43. Miller, M , Park, J. A., and Hanover, M Y (1991) Physiol. Rev. 71, 909-922
44. Xue, Z., Shan, X. Lapayre, B., and Melese, T. (1993) Eur. J. Cell Biol. 62, 13-22
45. Pasternack, M. S , Bleier, K. J., and Mclnerney, T. N (1991) J Biol. Chem. 266, 14703-14708
46. Kalderon, D., Roberts, B. L., Richardson, W. D., and Smith, A. E. (1984) Cell 39, 499-506
47. Shiver, J. W., Su, L., and Henkart, P. A. (1992) Cell 71, 315-322
48. Heusel, J. W., Wesselschmidt, R. L , Shresta, S., Russell, J. H., and Ley, T. J. (1994) Cell 76, 977-987
49. Jacobson, M., Burne, J. F., and Raff, M. C. (1994) EMBO J. 13, 1899-1910
50. Nakajima, H , Golstein, P., and Henkart, P. A. (1995) J. Exp. Med. 181, 1905-1910
51. Vaux, D , Haecker, G., and Strasser, A. (1994) Cell 76, 777-779
52. Yuan, J., Shaham, S., Ledoux, S., Ellis, H. M., and Horvitz, H. R. (1993) Cell 75, 641-652
53. Miura, M , Zhu, H., Rotello, R., Hartwieg, E. A., and Yuan, J. (1993) Cell 75, 653-660
54. Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C (1994) Nature 371, 346-347
55. Nicholson, D. W., Ali, A., Thornberry, N. A., and Villaincourt, J. P. (1995) Nature 376, 37-43
56. Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zens, Z., Beidler, D. R., Poirier, G G , Salvesen, G S., and Dixit, V. (1995) Cell 81, 801-809
57. Fernandes-Alnemri, T., Litwack, G., and Alnemri, E. (1995) Cancer Res 55, 2737-2742
58. Kaufmann, S. H., Desnoyers, S., Ottaviano, M., Davidson, N. E., and Poirier, G. G. (1993) Cancer Res. 53, 3976-3985
59. Earnshaw, W. C (1995) Curr. Opin. Cell Biol. 7, 337-343
60. Darmon, A. J., Nicholson, D. W , and Bleackley, R. C. (1995) Nature 377, 446-448