Stoichiometry of 7-ethoxycoumarin metabolism by cytochrome P450 2B1 wild-type and five active-site mutants

FEBS Letters

Volumn 416, Issue 1, 1997, Pages 77-80

  Fang, Xiaojun ^a   Kobayashi, Yasuna ^a   Halpert, James R ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

7 Ethoxycoumarin; Active site mutant; Cytochrome P450 2B1; Hydrogen peroxide; Stoichiometry; Uncoupling

Indexed keywords

7 ETHOXYCOUMARIN; CYTOCHROME; CYTOCHROME P450; DRUG METABOLIZING ENZYME; HYDROGEN PEROXIDE;

ARTICLE; DRUG BINDING SITE; DRUG METABOLISM; HUMAN; MUTANT; PRIORITY JOURNAL; STOICHIOMETRY;

BINDING SITES; COUMARINS; CYTOCHROME P-450 CYP2B1; HYDROGEN PEROXIDE; METHYLATION; MUTATION; NADP; RECOMBINANT PROTEINS; WATER;

EID: 0030780221     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)01173-3     Document Type: Article

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