Extinction of Rac1 and Cdc42Hs signalling defines a novel p53-dependent apoptotic pathway

Oncogene

Volumn 19, Issue 20, 2000, Pages 2377-2385

  Lassus, Patrice ^a,c   Roux, Pierre ^b   Zugasti, Olivier ^a   Philips, Alexandre ^a   Fort, Philippe ^b   Hibner, Urszula ^a  

^a INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

^b Centre National de la Recherche Scientifique   (France)

^c Watson School of Biological Sciences   (United States)

Author keywords

Adhesion; Apoptosis; Cdc42Hs; MAPK; p53; Rac1

Indexed keywords

GUANOSINE TRIPHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN CDC42; PROTEIN P53; RAC PROTEIN; RHO FACTOR; SYNAPTOPHYSIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DIFFERENTIATION; CELL GROWTH; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EXTRACELLULAR MATRIX; FIBROBLAST; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0034636442     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203553     Document Type: Article

References (54)

1. Ashkenazi A and Dixit VM. (1998). Science, 281, 1305-1308.
2. Aspenstrom P, Lindberg U and Hall A. (1996). Curr. Biol., 6, 70-75.
3. Bazenet CE, Mota MA and Rubin LL. (1998). Proc. Natl. Acad. Sci. USA, 95, 3984-3989.
4. Brunet A, Bonni A, Zigmond M, Lin M, Juo P, Hu L, Anderson M, Arden K, Blenis J and Greenberg M. (1999). Cell, 96, 857-868.
5. Cardone MH, Roy N, Stennicke HR, Salvesen GS, Franke TF, Stanbridge E, Frisch S and Reed JC. (1998). Science, 282, 1318-1321.
6. Carpenter CL and Cantley LC. (1996). Curr. Opin. Cell Biol., 8, 153-158.
7. Chuang TH, Hahn KM, Lee JD, Danley DE and Bokoch GM. (1997). Mol. Biol. Cell, 8, 1687-1698.
8. Coso OA, Chiariello M, Yu JC, Teramoto H, Crespo P, Xu NG, Miki T and Gutkind JS. (1995). Cell, 81, 1137-1146.
9. Cuenda A, Rouse J, Doza YN, Meier R, Cohen P, Gallagher TF, Young PR and Lee JC. (1995). FEBS Lett., 364, 229-233.
10. Donovan FM, Pike CJ, Cotman CW and Cunningham DD. (1997). J. Neurosci., 17, 5316-5326.
11. Downward J. (1998). Curr. Opin. Genet. Dev., 8, 49-54.
12. Dudley DT, Pang L, Decker SJ, Bridges AJ and Saltiel AR. (1995). Proc. Natl. Acad. Sci. USA, 92, 7686-7689.
13. Dutartre H. Davoust J, Gorvel JP and Chavrier P. (1996). J. Cell Sci., 109, 367-377.
14. Evan G and Littlewood T. (1998). Science, 281, 1317-1322.
15. Feig L and Cooper GM. (1988). Mol. Cell. Biol., 8, 3235-3243.
16. Fort P. (1999). Prog. Molec. Subcell. Biol., 22, 159-181.
17. Franke TF and Cantley LC. (1997). Nature, 390, 116-117.
18. Franke TF, Kaplan DR and Cantley LC. (1997). Cell. 88, 435-437.
19. Fukasawa and Vande Woude GF. (1997). Mol. Cell. Biol., 17, 506-518.
20. Gavrieli Y, Sherman Y and Ben-Sasson SA. (1992). J. Cell Biol., 119, 493-501.
21. Giaccia AJ and Kastan MB. (1998). Genes Dev., 12, 2973-2983.
22. Goillot E, Raingeaud J, Ranger A, Tepper RI, Davis RJ, Harlow E and Sanchez I. (1997). Proc. Natl. Acad. Sci. USA, 94, 3302-3307.
23. Hall A. (1998). Science, 279, 509-514.
24. Hansen R and Oren M. (1997). Curr. Opin. Cell Biol., 7, 46-51.
25. Harvey D and Levine AJ. (1991). Genes Dev., 5, 2375-2385.
26. Jimenez LA, Zanella C, Fung H, Janssen YM, Vacek P, Charland C, Goldberg J and Mossman BT. (1997). Am. J. Physiol., 273, L1029-L1035.
27. Joneson T and Bar-Sagi D. (1999). Mol. Cell. Biol., 19, 5892-5901.
28. Kauffman-Zeh A, Rodriguez-Viciana P, Ullrich E, Gilbert C, Coffer P, Downward J and Evan G. (1997). Nature, 385, 544-548.
29. Kern SE, Pietenpol JA, Thiagalingam S, Seymour A, Kinzler KW and Vogelstein B. (1992). Science, 256, 827-830.
30. Khwaja A and Downward J. (1997). J. Cell. Biol., 139, 1017-1023.
31. Ko LJ and Prives C. (1996). Genes Dev., 10, 1054-1072.
32. Lassus P, Ferlin M, Piette J and Hibner U. (1996). EMBO J., 15, 4566-4573.
33. Lassus P and Hibner U. (1998). Nuc. Acids Res., 26, 5233-5234.
34. Lenczowski JM, Dominguez L, Eder AM, King LB, Zacharchuk CM and Ashwell JD. (1997). Mol. Cell. Biol., 17, 170-181.
35. Levine AJ. (1997). Cell, 88, 323-331.
36. Liu ZG, Hsu H, Goeddel DV and Karin M. (1996). Cell, 87, 565-576.
37. Lloyd AC, Obermüller F, Staddon S, Barth CF, McMahon M and Land H. (1997). Genes Dev., 11, 663-677.
38. Martin SJ, Reutelingsperger CP, McGahon AJ, Rader JA, van Schie RC, LaFace DM and Green DM. (1995). J. Exp. Med., 182, 1545-1556.
39. Mayo MW, Wang C-Y, Cogswell PC, Rogers-Graham KS, Lowe SW, Der CJ and Baldwin Jr AS. (1997). Science, 278, 1812-1815.
40. Minden A, Lin A, McMahon M, Lange CC, Derijard B, Davis RJ, Johnson GL and Karin M. (1994). Science, 266, 1719-1723.
41. Moorman JP, Bobak DA and Hahn CS. (1996). J. Immunol., 156, 4146-4153.
42. Ory K, Legros Y, Auguin C and Soussi T. (1994). EMBO J., 13, 3496-3504.
43. Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM and Donner DB. (1999). Nature, 401, 82-85.
44. Palmero I, Pantoja C and Serrano M. (1998). Nature, 395, 125-126.
45. Park HO, Bi E, Pringle JR and Herskowitz I. (1997). Proc. Natl. Acad. Sci. USA, 94, 4463-4468.
46. Prives C. (1998). Cell, 95, 5-8.
47. Raff MC. (1992). Nature, 356, 397-400.
48. Romashkova JA and Makarov SS. (1999). Nature, 401, 86-89.
49. Roux P, Gauthier-Rouvière C, Doucet-Brutin S and Fort P. (1997). Curr. Biol., 7, 629-637.
50. Schulze-Osthoff K, Ferrari D, Los M, Wesselborg S and Peter ME. (1998). Eur. J. Biochem., 254, 439-459.
51. Serrano M, Lin AW, McCurrach ME, Beach D and Lowe SW. (1997). Cell, 88, 593-602.
52. Symons M, Derry JM, Karlak B, Jiang S, Lemahieu V, Mccormick F, Francke U and Abo A. (1996). Cell, 84, 723-734.
53. Thompson CB. (1995). Science, 267, 1456-1462.
54. Xia Z, Dickens M, Raingeaud J, Davis RJ and Greenberg ME. (1995). Science, 270, 1326-1331.