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Volumn 17, Issue 1, 1997, Pages 506-518

Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P53;

EID: 0031035639     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.1.506     Document Type: Article
Times cited : (110)

References (100)
  • 1
    • 0028980494 scopus 로고
    • p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts
    • Agarwal, M. L., A. Agarwal, W. R. Taylor, and G. R. Stark. 1995. p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. Proc. Natl. Acad. Sci. USA 92:8493-8497.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8493-8497
    • Agarwal, M.L.1    Agarwal, A.2    Taylor, W.R.3    Stark, G.R.4
  • 2
    • 0025283763 scopus 로고
    • Identification of multiple epidermal growth factor-stimulated protein serine/threonine kinases from Swiss 3T3 cells
    • Ahn, N. G., J. E. Weiel, C. P. Chan, and E. G. Krebs. 1990. Identification of multiple epidermal growth factor-stimulated protein serine/threonine kinases from Swiss 3T3 cells. J. Biol. Chem. 265:11487-11494.
    • (1990) J. Biol. Chem. , vol.265 , pp. 11487-11494
    • Ahn, N.G.1    Weiel, J.E.2    Chan, C.P.3    Krebs, E.G.4
  • 4
    • 0025871767 scopus 로고
    • Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation: Characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase
    • Alvarez, E., I. C. Northwood, F. A. Gonzalez, D. Latour, A. Seth, C. Abate, T. Curran, and R. J. Davis. 1991. Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation: characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase. J. Biol. Chem. 266:15277-15285.
    • (1991) J. Biol. Chem. , vol.266 , pp. 15277-15285
    • Alvarez, E.1    Northwood, I.C.2    Gonzalez, F.A.3    Latour, D.4    Seth, A.5    Abate, C.6    Curran, T.7    Davis, R.J.8
  • 5
    • 0025040233 scopus 로고
    • Suppression of human colorectal carcinoma cell growth by wild-type p53
    • Baker, S. J., S. Markowitz, E. R. Fearon, J. K. Willson, and B. Vogelstein. 1990. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 249:912-915.
    • (1990) Science , vol.249 , pp. 912-915
    • Baker, S.J.1    Markowitz, S.2    Fearon, E.R.3    Willson, J.K.4    Vogelstein, B.5
  • 6
    • 0015898815 scopus 로고
    • Evidence for helper independent murine sarcoma virus. I. Segregation of replication-defective and transformation-defective viruses
    • Ball, J., J. A. McCarter, and S. M. Sunderland. 1973. Evidence for helper independent murine sarcoma virus. I. Segregation of replication-defective and transformation-defective viruses. Virology 56:268-284.
    • (1973) Virology , vol.56 , pp. 268-284
    • Ball, J.1    McCarter, J.A.2    Sunderland, S.M.3
  • 7
    • 0026070065 scopus 로고
    • Friend virus-induced erythroleukemia and the multistage nature of cancer
    • Ben-David, Y., and A. Bernstein. 1991. Friend virus-induced erythroleukemia and the multistage nature of cancer. Cell 66:831-834.
    • (1991) Cell , vol.66 , pp. 831-834
    • Ben-David, Y.1    Bernstein, A.2
  • 8
    • 0019308627 scopus 로고
    • Biological activity of cloned Moloney sarcoma virus DNA: Terminally redundant sequences may enhance transformation efficiency
    • Blair, D. G., W. McClements, M. Oskarsson, P. Fischinger, and G. F. Vande Woude. 1980. Biological activity of cloned Moloney sarcoma virus DNA: terminally redundant sequences may enhance transformation efficiency. Proc. Natl. Acad. Sci. USA 77:3504-3508.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 3504-3508
    • Blair, D.G.1    McClements, W.2    Oskarsson, M.3    Fischinger, P.4    Vande Woude, G.F.5
  • 9
    • 0027488642 scopus 로고
    • Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction
    • Cai, H., P. Erhardt, J. Troppmair, M. T. Diaz-Meco, G. Sithanandam, U. R. Rapp, J. Moscat, and G. M. Cooper. 1993. Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction. Mol. Cell. Biol. 13:7645-7651.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7645-7651
    • Cai, H.1    Erhardt, P.2    Troppmair, J.3    Diaz-Meco, M.T.4    Sithanandam, G.5    Rapp, U.R.6    Moscat, J.7    Cooper, G.M.8
  • 11
    • 0029099361 scopus 로고
    • Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice
    • Bouffler, S. D., C. J. Kemp, A. Balmain, and R. Cox. 1995. Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice. Cancer Res. 55:3883-3889.
    • (1995) Cancer Res. , vol.55 , pp. 3883-3889
    • Bouffler, S.D.1    Kemp, C.J.2    Balmain, A.3    Cox, R.4
  • 12
    • 0025611503 scopus 로고
    • Genetic mechanisms of tumor suppression by the human p53 gene
    • Chen, P.-L., Y. M. Chen, R. Bookstein, and W.-H. Lee. 1990. Genetic mechanisms of tumor suppression by the human p53 gene. Science 250:1576-1580.
    • (1990) Science , vol.250 , pp. 1576-1580
    • Chen, P.-L.1    Chen, Y.M.2    Bookstein, R.3    Lee, W.-H.4
  • 15
    • 0028228616 scopus 로고
    • Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
    • Cowley, S., H. Paterson, P. Kemp, and C. J. Marshall. 1994. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77:841-852.
    • (1994) Cell , vol.77 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 17
    • 0028338927 scopus 로고
    • The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle
    • Denko, N. C., A. J. Giaccia, J. R. Stringer, and P. J. Stambrook. 1994. The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle. Proc. Natl. Acad. Sci. USA 91:5124-5128.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5124-5128
    • Denko, N.C.1    Giaccia, A.J.2    Stringer, J.R.3    Stambrook, P.J.4
  • 18
    • 0026641090 scopus 로고
    • Activation of mitogen-activated protein kinase by v-Raf in NIH/3T3 cells and in vitro
    • Dent, P., W. Haser, T. A. Haystead, L. A. Vincent, T. M. Roberts, and T. W. Sturgill. 1992. Activation of mitogen-activated protein kinase by v-Raf in NIH/3T3 cells and in vitro. Science 257:1404-1407.
    • (1992) Science , vol.257 , pp. 1404-1407
    • Dent, P.1    Haser, W.2    Haystead, T.A.3    Vincent, L.A.4    Roberts, T.M.5    Sturgill, T.W.6
  • 19
    • 0027155140 scopus 로고
    • Transfected c-Ha-ras oncogene enhances karyotypic instability and integrates predominantly in aberrant chromosomes
    • de Vries, J. E., F. H. Kornips, P. Marx, F. T. Bosman, J. P. Geraedts, and J. ten Kate. 1993. Transfected c-Ha-ras oncogene enhances karyotypic instability and integrates predominantly in aberrant chromosomes. Cancer Genet. Cytogenet. 67:35-43.
    • (1993) Cancer Genet. Cytogenet. , vol.67 , pp. 35-43
    • De Vries, J.E.1    Kornips, F.H.2    Marx, P.3    Bosman, F.T.4    Geraedts, J.P.5    Ten Kate, J.6
  • 24
    • 0025832626 scopus 로고
    • Structure, expression and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6
    • Erikson, R. L. 1991. Structure, expression and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6. J. Biol. Chem. 266:6007-6010.
    • (1991) J. Biol. Chem. , vol.266 , pp. 6007-6010
    • Erikson, R.L.1
  • 26
    • 0024382760 scopus 로고
    • The p53 protooncogene can act as a suppressor of transformation
    • Finlay, C. A., P. W. Hinds, and A. J. Levine. 1989. The p53 protooncogene can act as a suppressor of transformation. Cell 57:1083-1093.
    • (1989) Cell , vol.57 , pp. 1083-1093
    • Finlay, C.A.1    Hinds, P.W.2    Levine, A.J.3
  • 27
    • 0022486653 scopus 로고
    • In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes
    • Franza, B. R., Jr., K. Maruyama, J. I. Garrels, and H. E. Ruley. 1986. In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes. Cell 44:409-418.
    • (1986) Cell , vol.44 , pp. 409-418
    • Franza Jr., B.R.1    Maruyama, K.2    Garrels, J.I.3    Ruley, H.E.4
  • 29
    • 0028963355 scopus 로고
    • Mos overexpression in Swiss 3T3 cells induces meiotic-like alterations of the mitotic spindle
    • Fukasawa, K., and G. F. Vande Woude. 1995. Mos overexpression in Swiss 3T3 cells induces meiotic-like alterations of the mitotic spindle. Proc. Natl. Acad. Sci. USA 92:3430-3434.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3430-3434
    • Fukasawa, K.1    Vande Woude, G.F.2
  • 30
    • 0028852770 scopus 로고
    • Overexpression of mos oncogene product in Swiss 3T3 cells induces apoptosis preferentially during S-phase
    • Fukasawa, K., S. Rulong, J. Resau, P. Pinto da Silva, and G. F. Vande Woude. 1995. Overexpression of mos oncogene product in Swiss 3T3 cells induces apoptosis preferentially during S-phase. Oncogene 10:1-8.
    • (1995) Oncogene , vol.10 , pp. 1-8
    • Fukasawa, K.1    Rulong, S.2    Resau, J.3    Pinto Da Silva, P.4    Vande Woude, G.F.5
  • 32
    • 0025817292 scopus 로고
    • Excess wildtype p53 blocks initiation and maintenance of simian virus 40 transformation
    • Fukasawa, K., G. Sakoulas, R. E. Pollack, and S. Chen. 1991. Excess wildtype p53 blocks initiation and maintenance of simian virus 40 transformation. Mol. Cell. Biol. 11:3472-3483.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 3472-3483
    • Fukasawa, K.1    Sakoulas, G.2    Pollack, R.E.3    Chen, S.4
  • 33
    • 85035189241 scopus 로고    scopus 로고
    • Unpublished observation
    • Fukasawa, K. Unpublished observation.
    • Fukasawa, K.1
  • 34
    • 0026701092 scopus 로고
    • Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells
    • Gallego, C., S. K. Gupta, L. E. Heasley, N. X. Qian, and G. L. Johnson. 1992. Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells. Proc. Natl. Acad. Sci. USA 89:7355-7359.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7355-7359
    • Gallego, C.1    Gupta, S.K.2    Heasley, L.E.3    Qian, N.X.4    Johnson, G.L.5
  • 35
    • 0023874258 scopus 로고
    • Evidence that immunological variants of p53 represent alternative protein conformations
    • Gamble, J., and J. Milner. 1988. Evidence that immunological variants of p53 represent alternative protein conformations. Virology 162:452-458.
    • (1988) Virology , vol.162 , pp. 452-458
    • Gamble, J.1    Milner, J.2
  • 36
    • 0025248598 scopus 로고
    • Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form
    • Gannon, J. V., R. Greaves, R. Iggo, and D. P. Lane. 1990. Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. EMBO J. 9:1595-1602.
    • (1990) EMBO J. , vol.9 , pp. 1595-1602
    • Gannon, J.V.1    Greaves, R.2    Iggo, R.3    Lane, D.P.4
  • 37
    • 0026695645 scopus 로고
    • Phosphorylation of transcription factor p62 TCF by MAP kinase stimulates ternary complex formation at c-fos promoter
    • Gille, H., A. D. Sharrocks, and P. E. Shaw. 1992. Phosphorylation of transcription factor p62 TCF by MAP kinase stimulates ternary complex formation at c-fos promoter. Nature (London) 358:414-417.
    • (1992) Nature (London) , vol.358 , pp. 414-417
    • Gille, H.1    Sharrocks, A.D.2    Shaw, P.E.3
  • 39
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham, F. L., and A. J. van der Eb. 1973. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52:456-467.
    • (1973) Virology , vol.52 , pp. 456-467
    • Graham, F.L.1    Van Der Eb, A.J.2
  • 40
    • 0029001624 scopus 로고
    • p53 involvement in control of G2 exit of the cell cycle: Role in DNA damage-induced apoptosis
    • Guillouf, C., F. Rosselli, K. Krishnaraju, E. Moustacchi, B. Huffman, and D. A. Liebermann. 1995. p53 involvement in control of G2 exit of the cell cycle: role in DNA damage-induced apoptosis. Oncogene 10:2263-2270.
    • (1995) Oncogene , vol.10 , pp. 2263-2270
    • Guillouf, C.1    Rosselli, F.2    Krishnaraju, K.3    Moustacchi, E.4    Huffman, B.5    Liebermann, D.A.6
  • 41
    • 0026640629 scopus 로고
    • MAP kinase is constitutively activated in gip2 and src transformed Rat 1a fibroblasts
    • Gupta, S. K., C. Gallego, G. L. Johnson, and L. E. Heasley. 1992. MAP kinase is constitutively activated in gip2 and src transformed Rat 1a fibroblasts. J. Biol. Chem. 267:7987-7990.
    • (1992) J. Biol. Chem. , vol.267 , pp. 7987-7990
    • Gupta, S.K.1    Gallego, C.2    Johnson, G.L.3    Heasley, L.E.4
  • 42
    • 0028842340 scopus 로고
    • A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice
    • Harvey, M., H. Vogel, D. Morris, A. Bradley, A. Bernstein, and L. A. Donehower. 1995. A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice. Nat. Genet. 9:305-311.
    • (1995) Nat. Genet. , vol.9 , pp. 305-311
    • Harvey, M.1    Vogel, H.2    Morris, D.3    Bradley, A.4    Bernstein, A.5    Donehower, L.A.6
  • 44
    • 0025969355 scopus 로고
    • Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest
    • Hicks, G. G., S. E. Egan, A. H. Greenberg, and M. Mowat. 1991. Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest. Mol. Cell. Biol. 11:1344-1352.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1344-1352
    • Hicks, G.G.1    Egan, S.E.2    Greenberg, A.H.3    Mowat, M.4
  • 47
    • 0025265724 scopus 로고
    • Increased expression of mutant forms of p53 oncogene in primary lung cancer
    • Iggo, R., K. Gatter, J. Bartek, D. Lane, and A. L. Harris. 1990. Increased expression of mutant forms of p53 oncogene in primary lung cancer. Lancet 335:675-679.
    • (1990) Lancet , vol.335 , pp. 675-679
    • Iggo, R.1    Gatter, K.2    Bartek, J.3    Lane, D.4    Harris, A.L.5
  • 50
    • 0028927179 scopus 로고
    • P53. cell cycle control and apoptosis: Implications for cancer
    • Kastan, M. B., C. E. Canman, and C. J. Leonard. 1995. P53. cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Rev. 14:3-15.
    • (1995) Cancer Metastasis Rev. , vol.14 , pp. 3-15
    • Kastan, M.B.1    Canman, C.E.2    Leonard, C.J.3
  • 51
    • 0015117787 scopus 로고
    • Shrinkage necrosis: A distinct mode of cellular death
    • Kerr, J. F. R. 1971. Shrinkage necrosis: a distinct mode of cellular death. J. Pathol. 105:13-20.
    • (1971) J. Pathol. , vol.105 , pp. 13-20
    • Kerr, J.F.R.1
  • 52
  • 54
    • 0024431245 scopus 로고
    • High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene
    • Lavigueur, A., V. Maltby, D. Mock, J. Rossant, T. Pawson, and A. Bernstein. 1989. High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene. Mol. Cell. Biol. 9:3982-3991.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 3982-3991
    • Lavigueur, A.1    Maltby, V.2    Mock, D.3    Rossant, J.4    Pawson, T.5    Bernstein, A.6
  • 55
    • 0027285380 scopus 로고
    • p53 mutations increase resistance to ionizing radiation
    • Lee, J. M., and A. Bernstein. 1993. p53 mutations increase resistance to ionizing radiation. Proc. Natl. Acad. Sci. USA 90:5742-5746.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5742-5746
    • Lee, J.M.1    Bernstein, A.2
  • 56
    • 0028033027 scopus 로고
    • Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53 deficient mice
    • Lee, J. M., J. L. Abrahamson, R. Kandel, L. A. Donehower, and A. Bernstein. 1994. Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53 deficient mice. Oncogene 9:3731-3736.
    • (1994) Oncogene , vol.9 , pp. 3731-3736
    • Lee, J.M.1    Abrahamson, J.L.2    Kandel, R.3    Donehower, L.A.4    Bernstein, A.5
  • 58
    • 0028272507 scopus 로고
    • Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
    • Leevers, S. J., H. F. Paterson, and C. J. Marshall. 1994. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature (London) 369:411-414.
    • (1994) Nature (London) , vol.369 , pp. 411-414
    • Leevers, S.J.1    Paterson, H.F.2    Marshall, C.J.3
  • 59
    • 0029063175 scopus 로고
    • Activated H-ras rescues E1A-induced apoptosis and cooperates with E1A to overcome p53-dependent growth arrest
    • Lin, H.-J., V. Eviner, G. C. Prendergast, and E. White. 1995. Activated H-ras rescues E1A-induced apoptosis and cooperates with E1A to overcome p53-dependent growth arrest. Mol. Cell. Biol. 15:4536-4544.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4536-4544
    • Lin, H.-J.1    Eviner, V.2    Prendergast, G.C.3    White, E.4
  • 60
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone, L. R., A. White, J. Sprouse, E. Livanos, T. Jacks, and T. D. Tlsty. 1992. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70:923-935.
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, L.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tlsty, T.D.6
  • 61
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S. W., H. E. Ruley, T. Jacks, and D. E. Housman. 1993. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74:957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 64
    • 0027297647 scopus 로고
    • The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
    • Marais, R., J. Wynne, and R. Treisman. 1993. The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell 73:381-393.
    • (1993) Cell , vol.73 , pp. 381-393
    • Marais, R.1    Wynne, J.2    Treisman, R.3
  • 65
    • 0026093164 scopus 로고
    • Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein
    • Martinez, J., I. Georgoff, J. Martinez, and A. J. Levine. 1991. Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Genes Dev. 5:151-159.
    • (1991) Genes Dev. , vol.5 , pp. 151-159
    • Martinez, J.1    Georgoff, I.2    Martinez, J.3    Levine, A.J.4
  • 67
    • 0025111068 scopus 로고
    • Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
    • Michalovitz, D., O. Halevy, and M. Oren. 1990. Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell 62:671-680.
    • (1990) Cell , vol.62 , pp. 671-680
    • Michalovitz, D.1    Halevy, O.2    Oren, M.3
  • 68
    • 0021835959 scopus 로고
    • Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus
    • Mowat, M., A. Cheng, N. Kimura, A. Bernstein, and S. Benchimol. 1985. Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus. Nature (London) 314:633-636.
    • (1985) Nature (London) , vol.314 , pp. 633-636
    • Mowat, M.1    Cheng, A.2    Kimura, N.3    Bernstein, A.4    Benchimol, S.5
  • 69
    • 0027491327 scopus 로고
    • The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo
    • Nebreda, A. R., C. Hill, N. Gomez, P. Cohen, and T. Hunt. 1993. The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo. FEBS Lett. 333:183-187.
    • (1993) FEBS Lett. , vol.333 , pp. 183-187
    • Nebreda, A.R.1    Hill, C.2    Gomez, N.3    Cohen, P.4    Hunt, T.5
  • 70
    • 0027299967 scopus 로고
    • The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs
    • Nebreda, A. R., and T. Hunt. 1993. The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs. EMBO J. 12:1979-1986.
    • (1993) EMBO J. , vol.12 , pp. 1979-1986
    • Nebreda, A.R.1    Hunt, T.2
  • 71
    • 0028901847 scopus 로고
    • MAP kinase activation is essential for oncogenic transformation of NIH3T3 cells by Mos
    • Okazaki, K., and N. Sagata. 1995. MAP kinase activation is essential for oncogenic transformation of NIH3T3 cells by Mos. Oncogene 10:1149-1157.
    • (1995) Oncogene , vol.10 , pp. 1149-1157
    • Okazaki, K.1    Sagata, N.2
  • 73
    • 0020146919 scopus 로고
    • Detection of a transforming gene product in cells transformed by Moloney murine sarcoma virus
    • Papkoff, J., I. M. Verma, and T. Hunter. 1982. Detection of a transforming gene product in cells transformed by Moloney murine sarcoma virus. Cell 29:417-426.
    • (1982) Cell , vol.29 , pp. 417-426
    • Papkoff, J.1    Verma, I.M.2    Hunter, T.3
  • 75
    • 0024292712 scopus 로고
    • The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A
    • Phelps, W. C., C. L. Yee, K. Münger, and P. M. Howley. 1989. The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A. Cell 53:539-547.
    • (1989) Cell , vol.53 , pp. 539-547
    • Phelps, W.C.1    Yee, C.L.2    Münger, K.3    Howley, P.M.4
  • 76
    • 0026698006 scopus 로고
    • Stimulation of milogen-activated protein kinase by oncogenic Ras p21 in Xenopus oocytes. Requirement for Ras p21-GTPase-activating protein interaction
    • Pomerance, M., F. Schweighoffer, B. Tocque, and M. Pierre. 1992. Stimulation of milogen-activated protein kinase by oncogenic Ras p21 in Xenopus oocytes. Requirement for Ras p21-GTPase-activating protein interaction. J. Biol. Chem. 267:16155-16160.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16155-16160
    • Pomerance, M.1    Schweighoffer, F.2    Tocque, B.3    Pierre, M.4
  • 77
    • 0027462979 scopus 로고
    • Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro
    • Posada, J., N. Yew, N. G. Ahn, G. F. Vande Woude, and J. A. Cooper. 1993. Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro. Mol. Cell. Biol. 13:2546-2553.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2546-2553
    • Posada, J.1    Yew, N.2    Ahn, N.G.3    Vande Woude, G.F.4    Cooper, J.A.5
  • 81
    • 0027365944 scopus 로고
    • Multiple mechanisms of N-(phosphonoacetyl)-L-aspartate drug resistance in SV40-infected precrisis human fibroblasts
    • Schaefer, D. I., E. M. Livanos, A. E. White, and T. D. Tlsty. 1993. Multiple mechanisms of N-(phosphonoacetyl)-L-aspartate drug resistance in SV40-infected precrisis human fibroblasts. Cancer Res. 53:4946-4951.
    • (1993) Cancer Res. , vol.53 , pp. 4946-4951
    • Schaefer, D.I.1    Livanos, E.M.2    White, A.E.3    Tlsty, T.D.4
  • 82
    • 0026343730 scopus 로고
    • 2-terminal domain of c-Myc increases transactivation of gene expression
    • 2-terminal domain of c-Myc increases transactivation of gene expression. J. Biol. Chem. 266:23521-23524.
    • (1991) J. Biol. Chem. , vol.266 , pp. 23521-23524
    • Seth, A.1    Alvarez, E.2    Gupta, S.3    Davis, R.J.4
  • 83
    • 0026756618 scopus 로고
    • Oncogenic ras triggers the activation of 42-kDa mitogen-activated protein kinase in extracts of quiescent Xenopus oocytes
    • Shibuya, E. K., A. J. Polverino, E. Chang, M. Wigler, and J. V. Ruderman. 1992. Oncogenic ras triggers the activation of 42-kDa mitogen-activated protein kinase in extracts of quiescent Xenopus oocytes. Proc. Natl. Acad. Sci. USA 89:9831-9835.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9831-9835
    • Shibuya, E.K.1    Polverino, A.J.2    Chang, E.3    Wigler, M.4    Ruderman, J.V.5
  • 84
    • 0027272446 scopus 로고
    • Mos induces the in vitro activation of mitogen-activated protein kinases in lysates of frog oocytes and mammalian somatic cells
    • Shibuya, E. K., and J. U. Ruderman. 1993. Mos induces the in vitro activation of mitogen-activated protein kinases in lysates of frog oocytes and mammalian somatic cells. Mol. Biol. Cell 4:781-790.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 781-790
    • Shibuya, E.K.1    Ruderman, J.U.2
  • 86
    • 0028241533 scopus 로고
    • Activation of Raf as a result of recruitment to the plasma membrane
    • Stokoe, D., S. G. Macdonald, K. Cadwallader, M. Symons, and J. F. Hancock. 1994. Activation of Raf as a result of recruitment to the plasma membrane. Science 264:1463-1467.
    • (1994) Science , vol.264 , pp. 1463-1467
    • Stokoe, D.1    Macdonald, S.G.2    Cadwallader, K.3    Symons, M.4    Hancock, J.F.5
  • 87
    • 0024022067 scopus 로고
    • Comparison of the in vitro transforming activities of human papillomavirus types
    • Storey, A., D. Pim, A. Murray, K. Osborn, L. Banks, and L. Crawford. 1988. Comparison of the in vitro transforming activities of human papillomavirus types. EMBO J. 7:1815-1820.
    • (1988) EMBO J. , vol.7 , pp. 1815-1820
    • Storey, A.1    Pim, D.2    Murray, A.3    Osborn, K.4    Banks, L.5    Crawford, L.6
  • 88
    • 0023766145 scopus 로고
    • Insulinstimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II
    • Sturgill, T. W., L. B. Ray, E. Erikson, and J. L. Mailer. 1988. Insulinstimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. Nature (London) 334:715-718.
    • (1988) Nature (London) , vol.334 , pp. 715-718
    • Sturgill, T.W.1    Ray, L.B.2    Erikson, E.3    Mailer, J.L.4
  • 89
    • 0026534571 scopus 로고
    • Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases
    • Thomas, S. M., M. DeMarco, G. D'Arcangelo, S. Halegoua, and J. S. Brugge. 1992. Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Cell 68:1031-1040.
    • (1992) Cell , vol.68 , pp. 1031-1040
    • Thomas, S.M.1    Demarco, M.2    D'Arcangelo, G.3    Halegoua, S.4    Brugge, J.S.5
  • 90
    • 0027258955 scopus 로고
    • MAP kinase becomes stably activated at metaphase and is associated with microtubule-organizing centers during meiotic maturation of mouse oocytes
    • Verlhac, M.-H., H. de Pennart, B. Maro, M. H. Cobb, and H. J. Clarke. 1993. MAP kinase becomes stably activated at metaphase and is associated with microtubule-organizing centers during meiotic maturation of mouse oocytes. Dev. Biol. 158:330-340.
    • (1993) Dev. Biol. , vol.158 , pp. 330-340
    • Verlhac, M.-H.1    De Pennart, H.2    Maro, B.3    Cobb, M.H.4    Clarke, H.J.5
  • 91
    • 0029963057 scopus 로고    scopus 로고
    • Mos is required for MAP kinase activation and is involved in microtubule organization during meiotic maturation in the mouse
    • Verlhac, M.-H., J. Z. Kubiak, M. Weber, G. Géraud, W. H. Colledge, M. J. Evans, and B. Maro. 1996. Mos is required for MAP kinase activation and is involved in microtubule organization during meiotic maturation in the mouse. Development 122:815-822.
    • (1996) Development , vol.122 , pp. 815-822
    • Verlhac, M.-H.1    Kubiak, J.Z.2    Weber, M.3    Géraud, G.4    Colledge, W.H.5    Evans, M.J.6    Maro, B.7
  • 93
    • 0027073111 scopus 로고
    • Activation of protein serine-threonine kinases p42, p63, and p87 in Rous sarcoma virus-transformed cells: Signal transduction/transformation dependent MBP kinases
    • Wang, H.-C., and R. L. Erikson. 1992. Activation of protein serine-threonine kinases p42, p63, and p87 in Rous sarcoma virus-transformed cells: signal transduction/transformation dependent MBP kinases. Mol. Biol. Cell 3:1329-1337.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 1329-1337
    • Wang, H.-C.1    Erikson, R.L.2
  • 96
    • 0026523559 scopus 로고
    • Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK
    • Wood, K. W., C. Sarnecki, T. M. Roberts, and J. Blenis. 1992. ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Cell 68:1041-1050.
    • (1992) Cell , vol.68 , pp. 1041-1050
    • Wood, K.W.1    Sarnecki, C.2    Roberts, T.M.3    Blenis, J.4
  • 97
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie, A. H. 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature (London) 284:555-556.
    • (1980) Nature (London) , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 98
    • 0027512563 scopus 로고
    • Mos and the cell cycle: The molecular basis of the transformed phenotype
    • Yew, N., M. Strobel, and G. F. Vande Woude. 1993. Mos and the cell cycle: the molecular basis of the transformed phenotype. Curr. Opin. Genet. Dev. 3:19-25.
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 19-25
    • Yew, N.1    Strobel, M.2    Vande Woude, G.F.3
  • 99
    • 0022472735 scopus 로고
    • Monoclonal antibody analysis of p53 expression in normal and transformed cells
    • Yewdell, J. W., J. V. Gannon, and D. P. Lane. 1986. Monoclonal antibody analysis of p53 expression in normal and transformed cells. J. Virol. 59:444-452.
    • (1986) J. Virol. , vol.59 , pp. 444-452
    • Yewdell, J.W.1    Gannon, J.V.2    Lane, D.P.3
  • 100
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • Yin, Y., M. A. Tainsky, F. Z. Bischoff, L. C. Strong, and G. M. Wahl. 1992. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70:937-948.
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin, Y.1    Tainsky, M.A.2    Bischoff, F.Z.3    Strong, L.C.4    Wahl, G.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.