Amyloid β-protein deposition in the leptomeninges and cerebral cortex

Annals of Neurology

Volumn 42, Issue 6, 1997, Pages 899-908

  Shinkai, Yasuhisa ^a   Yoshimura, Masahiro ^b   Morishima Kawashima, Maho ^a   Ito, Yuji ^d   Shimada, Hiroyuki ^c   Yanagisawa, Katsuhiko ^e   Ihara, Yasuo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Tokyo Medical Examiner's Office   (Japan)

^c TOKYO MEDICAL UNIVERSITY   (Japan)

^d Tokyo Metropolitan Tama Geriatric Hospital   (Japan)

^e NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN;

AGED; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; BRAIN BIOPSY; ENZYME IMMUNOASSAY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; SENILE PLAQUE; TISSUE DISTRIBUTION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AUTOPSY; CEREBRAL CORTEX; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; SENILE PLAQUES;

EID: 0031442299     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.410420612     Document Type: Article

References (29)

1. Selkoe DJ. Alzheimer's disease: a central role for amyloid. J Neuropathol Exp Neurol 1994;53:438-447
2. Vinters HV. Cerebral amyloid angiopathy. A critical review. Stroke 1987;18:311-324
3. Kang J, Lemaire H-G, Unterbeck A, et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 1987;325:733-736
4. Mori H, Takio K, Ogawara M, et al. Mass spectrometry of purified amyloid β protein in Alzheimer's disease. J Biol Chem 1992;267:17082-17086
5. Roher AE, Lowenson JD, Clarke S, et al. Structural alteration in the peptide backbone of β-amyloid core protein may account for its deposition and stability in Alzheimer's disease. J Biol Chem 1993;268:3072-3083
6. Jarrett JT, Berger EP, Lansbury PT Jr. The carboxyl terminus of the β amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 1993;32:4693-4697
7. Shinkai Y, Yoshimura M, Ito Y, et al. Amyloid β-proteins 1-40 and 1-42(43) in the soluble fraction of extra- and intracranial blood vessels. Ann Neurol 1995;38:421-428
8. Khachaturian ZS. Diagnosis of Alzheimer's disease. Arch Neurol 1985;42:1097-1104
9. Suzuki N, Iwatsubo T, Odaka A, et al. High tissue content of soluble β1-40 is linked to cerebral amyloid angiopathy. Am J Pathol 1994;145:452-460
10. Suzuki N, Cheung TT, Cai X-D, et al. An increased percentage of long amyloid β-protein is secreted by familial amyloid β-protein precursor (βAPP717) mutants. Science 1994;264: 1336-1340
11. Kim KS, Miller DL, Sapienza VJ, et al. Production and characterization of monoclonal antibodies reactive to synthetic cerebrovascular amyloid peptide. Neurosci Res Commun 1988;2: 121-130
12. Gravina SA, Ho L, Eckman CB, et al. Amyloid β protein (Aβ) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at Aβ40 or Aβ42(43). J Biol Chem 1995;270:7013-7016
13. Iwatsubo T, Odaka A, Suzuki N, et al. Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: evidence that an initially deposited species is Aβ42(43). Neuron 1994;13:45-53
14. Yanagisawa K, Odaka A, Suzuki N, et al. GM1 ganglioside-bound amyloid β-protein (Aβ): a possible form of preamyloid in Alzheimer's disease. Nat Med 1995;1:1062-1066
15. Iizuka T, Shoji M, Harigaya Y, et al. Amyloid β-protein ending at Thr43 is a minor component of some diffuse plaques in the Alzheimer's disease brain, but is not found in cerebrovascular amyloid. Brain Res 1995;702:275-278
16. Pirttila T, Kim KS, Mehta PD, et al. Soluble amyloid β-protein in the cerebrospinal fluid from patients with Alzheimer's disease, vascular dementia and controls. J Neurol Sci 1994;127: 90-95
17. Ida N, Hartmann T, Pantel J, et al. Analysis of heterogeneous βA4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive western blot assay. J Biol Chem 1996;271:22908-22914
18. Naslund J, Thyberg J, Tjernberg LO, et al. Characterization of stable complexes involving apolipoprotein E and the amyloid β peptide in Alzheimer's disease brain. Neuron 1995;15:219-228
19. Miller DL, Papayannopoulos IA, Styles J, et al. Peptide compositions of the cerebrovascular and senile plaque deposits of Alzheimer's disease. Arch Biochem Biophys 1993;301:41-52
20. Tamaoka A, Odaka A, Ishibashi Y, et al. APP 717 missense mutation affects the ratio of amyloid β protein species (Aβ1-42(43) and Aβ1-40) in familial Alzheimer's disease brain. J Biol Chem 1995;269:32721-32724
21. Naslund J, Schierhorn A, Hellman U, et al. Relative abundance of Alzheimer Aβ amyloid peptide variants in Alzheimer disease and normal aging. Proc Natl Acad Sci USA 1994;91:8378-8382
22. Frucht SJ, Koo EH. β-Amyloid protein is higher in Alzheimer's disease brains: description of a quantitative biochemical assay. J Neuropathol Exp Neurol 1993;52:640-647
23. Iwatsubo T, Mann DMA, Odaka A, et al. Amyloid β-protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in Down's syndrome. Ann Neurol 1995;37:294-299
24. Joachim CL, Duffy LK, Morris JH, Selkoe DJ. Protein chemical and immunocytochemical studies of meningovascular β-amyloid protein in Alzheimer's disease and normal aging. Brain Res 1988;474:100-111
25. Roher AE, Lowenson JD, Clarke S, et al. β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implication for the pathology of Alzheimer's disease. Proc Natl Acad Sci USA 1993;90:10836-10840
26. Hamano T, Shinkai Y, Yanagisawa K, et al. Amyloid β-protein (Aβ) accumulation in the leptomeninges during aging and in Alzheimer's disease. J Neuropathol Exp Neurol 1997;56:922-932
27. Kanemaru K, Hasegawa M, Shimada H, Ihara Y. The presence of a novel protein in calf serum that recognizes β-amyloid in the formalin-fixed section. Am J Pathol 1990;137:677-687
28. Frackowiak J, Zoltowska A, Wisniewski HM. Non-fibrillar β-amyloid protein is associated with smooth muscle cells of vessel walls in Alzheimer disease. J Neuropathol Exp Neurol 1994;53: 637-645
29. Teller JK, Russo C, DeBusk LM, et al. Presence of soluble amyloid β-peptide precede amyloid plaque formation in Down's syndrome. Nat Med 1996;2:93-95