The use of topographical constraints in receptor mapping: Investigation of the topographical requirements of the tryptophan 30 residue for receptor binding of Asp-Tyr-D-Phe-Gly-Trp-(N-Me)Nle-Asp-Phe-NH2 (SNF 9007), a cholecystokinin (26-33) analogue that binds to both CCK-B and δ-opioid receptors

Journal of Medicinal Chemistry

Volumn 39, Issue 20, 1996, Pages 4120-4124

  Boteju, Lakmal W ^a,b   Nikiforovich, Gregory V ^a,c   Haskell Luevano, Carrie ^a   Fang, Su Nan ^a   Zalewska, Teresa ^d   Stropova, Dagmar ^d   Yamamura, Henry I ^d   Hruby, Victor J ^a  

^a University of Arizona   (United States)

^b PRINCETON UNIVERSITY   (United States)

^c WASHINGTON UNIVERSITY   (United States)

^d UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ OCTAPEPTIDE DERIVATIVE; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; SIGMA OPIATE RECEPTOR; SNF 9007; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENERGY; GUINEA PIG; MOLECULAR MODEL; NONHUMAN; PANCREAS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL MEMBRANE; CEREBRAL CORTEX; CHOLECYSTOKININ; GUINEA PIGS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PANCREAS; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RECEPTOR, CHOLECYSTOKININ B; RECEPTORS, CHOLECYSTOKININ; RECEPTORS, OPIOID, DELTA; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTOPHAN;

EID: 0029835341     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960078j     Document Type: Article

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