-
1
-
-
3643120790
-
Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells
-
Xu D., Chan W.L., Leung B.P., Hunter D., Schulz K., Carter R.W., McInnes I.B., Robinson J.H., Liew F.Y. Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells. J Exp Med. 188:1998;1485-1492.
-
(1998)
J Exp Med
, vol.188
, pp. 1485-1492
-
-
Xu, D.1
Chan, W.L.2
Leung, B.P.3
Hunter, D.4
Schulz, K.5
Carter, R.W.6
McInnes, I.B.7
Robinson, J.H.8
Liew, F.Y.9
-
2
-
-
0032193770
-
IL-12 upregulates IL-18 receptor expression on T cells, Th1 cells and B cells: Synergism with IL-18 for IFN-γ production
-
Yoshimoto T., Takeda K., Tanaka T., Ohkusu K., Kashiwamura S., Okamura H., Akira S., Nakanishi K. IL-12 upregulates IL-18 receptor expression on T cells, Th1 cells and B cells: synergism with IL-18 for IFN-γ production. J Immunol. 161:1998;3400-3407.
-
(1998)
J Immunol
, vol.161
, pp. 3400-3407
-
-
Yoshimoto, T.1
Takeda, K.2
Tanaka, T.3
Ohkusu, K.4
Kashiwamura, S.5
Okamura, H.6
Akira, S.7
Nakanishi, K.8
-
3
-
-
0031931392
-
IL-18 (IFN-γ-inducing factor) regulates early cytokine production in, and promotes resolution of, bacterial infection in mice
-
Bohn E., Sing A., Zumbihl R., Bielfeldt C., Okamura H., Kurimoto M., Heesemann J., Autenrieth I.B. IL-18 (IFN-γ-inducing factor) regulates early cytokine production in, and promotes resolution of, bacterial infection in mice. J Immunol. 160:1998;299-307.
-
(1998)
J Immunol
, vol.160
, pp. 299-307
-
-
Bohn, E.1
Sing, A.2
Zumbihl, R.3
Bielfeldt, C.4
Okamura, H.5
Kurimoto, M.6
Heesemann, J.7
Autenrieth, I.B.8
-
4
-
-
0032913015
-
Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent Salmonella typhimurium
-
Mastroeni P., Clare S., Khan S., Harrison J.A., Hormaeche C.E., Okamura H., Kurimoto M., Dougan G. Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent Salmonella typhimurium. Infect Immun. 67:1999;478-483.
-
(1999)
Infect Immun
, vol.67
, pp. 478-483
-
-
Mastroeni, P.1
Clare, S.2
Khan, S.3
Harrison, J.A.4
Hormaeche, C.E.5
Okamura, H.6
Kurimoto, M.7
Dougan, G.8
-
5
-
-
0032702577
-
Role of endogenous interleukin-18 in resolving wild-type and attenuated Salmonella typhimurium infections
-
Dybing J.K., Walters N., Pascual D.W. Role of endogenous interleukin-18 in resolving wild-type and attenuated Salmonella typhimurium infections. Infect Immun. 67:1999;6242-6248.
-
(1999)
Infect Immun
, vol.67
, pp. 6242-6248
-
-
Dybing, J.K.1
Walters, N.2
Pascual, D.W.3
-
6
-
-
0033029561
-
Combined effects of IL-12 and IL-18 on the clinical course and local cytokine production in murine pulmonary infection with Cryptococcus neoformans
-
Qureshi M.H., Zhang T., Koguchi Y., Nakashima K., Okamura H., Kurimoto M., Kawakami K. Combined effects of IL-12 and IL-18 on the clinical course and local cytokine production in murine pulmonary infection with Cryptococcus neoformans. Eur J Immunol. 29:1999;643-649.
-
(1999)
Eur J Immunol
, vol.29
, pp. 643-649
-
-
Qureshi, M.H.1
Zhang, T.2
Koguchi, Y.3
Nakashima, K.4
Okamura, H.5
Kurimoto, M.6
Kawakami, K.7
-
7
-
-
0032924518
-
Role of interleukin-18 (IL-18) in mycobacterial infection in IL-18-gene-disrupted mice
-
Sugawara I., Yamada H., Kaneko H., Mizuno S., Takeda K., Akira S. Role of interleukin-18 (IL-18) in mycobacterial infection in IL-18-gene-disrupted mice. Infect Immun. 67:1999;2585-2589.
-
(1999)
Infect Immun
, vol.67
, pp. 2585-2589
-
-
Sugawara, I.1
Yamada, H.2
Kaneko, H.3
Mizuno, S.4
Takeda, K.5
Akira, S.6
-
8
-
-
18844481515
-
Defective NK cell activity and Th1 responses in IL-18-deficient mice
-
Takeda K., Tsutsui H., Yoshimoto T., Adachi O., Yoshida N., Kishimoto T., Okamura H., Nakanishi K., Akira S. Defective NK cell activity and Th1 responses in IL-18-deficient mice. Immunity. 8:1998;383-390.
-
(1998)
Immunity
, vol.8
, pp. 383-390
-
-
Takeda, K.1
Tsutsui, H.2
Yoshimoto, T.3
Adachi, O.4
Yoshida, N.5
Kishimoto, T.6
Okamura, H.7
Nakanishi, K.8
Akira, S.9
-
9
-
-
0033563009
-
IL-18 promotes type 1 cytokine production from NK cells and T cells in human intracellular infection
-
Garcia V.E., Uyemura K., Sieling P.A., Ochoa M.T., Morita C.T., Okamura H., Kurimoto M., Rea T.H., Modlin R.L. IL-18 promotes type 1 cytokine production from NK cells and T cells in human intracellular infection. J Immunol. 162:1999;6114-6121.
-
(1999)
J Immunol
, vol.162
, pp. 6114-6121
-
-
Garcia, V.E.1
Uyemura, K.2
Sieling, P.A.3
Ochoa, M.T.4
Morita, C.T.5
Okamura, H.6
Kurimoto, M.7
Rea, T.H.8
Modlin, R.L.9
-
10
-
-
0033198145
-
Altered immune responses and susceptibility to Leishmania major and Staphylococcus aureus infection in IL-18-deficient mice
-
This paper shows that IL-18-deficient mice are susceptible to parasitic and bacterial pathogens.
-
Wei X.Q., Leung B.P., Niedbala W., Piedrafita D., Feng G.J., Sweet M., Dobbie L., Smith A.J., Liew F.Y. Altered immune responses and susceptibility to Leishmania major and Staphylococcus aureus infection in IL-18-deficient mice. J Immunol. 163:1999;2821-2828. This paper shows that IL-18-deficient mice are susceptible to parasitic and bacterial pathogens.
-
(1999)
J Immunol
, vol.163
, pp. 2821-2828
-
-
Wei, X.Q.1
Leung, B.P.2
Niedbala, W.3
Piedrafita, D.4
Feng, G.J.5
Sweet, M.6
Dobbie, L.7
Smith, A.J.8
Liew, F.Y.9
-
11
-
-
0033526110
-
Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice
-
Kanakaraj P., Ngo K., Wu Y., Angulo A., Ghazal P., Harris C.A., Siekierka J.J., Peterson P.A., Fung-Leung W.P. Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice. J Exp Med. 189:1999;1129-1138.
-
(1999)
J Exp Med
, vol.189
, pp. 1129-1138
-
-
Kanakaraj, P.1
Ngo, K.2
Wu, Y.3
Angulo, A.4
Ghazal, P.5
Harris, C.A.6
Siekierka, J.J.7
Peterson, P.A.8
Fung-Leung, W.P.9
-
12
-
-
0032555904
-
A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells
-
Kaplan M.H., Wurster A.L., Grusby M.J. A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells. J Exp Med. 188:1998;1191-1196.
-
(1998)
J Exp Med
, vol.188
, pp. 1191-1196
-
-
Kaplan, M.H.1
Wurster, A.L.2
Grusby, M.J.3
-
13
-
-
0033583431
-
Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon γ production from CD4+ versus CD8+ T cells
-
Carter L.L., Murphy K.M. Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon γ production from CD4+ versus CD8+ T cells. J Exp Med. 189:1999;1355-1360.
-
(1999)
J Exp Med
, vol.189
, pp. 1355-1360
-
-
Carter, L.L.1
Murphy, K.M.2
-
14
-
-
0033556145
-
IL-12 is not required for induction of type 1 cytokine responses in viral infections
-
Despite the critical role for IL-12 in resistance to many intracellular pathogens, this paper shows for the first time that IL-12-independent protective responses to LCMV and VSV can be generated.
-
Oxenius A., Karrer U., Zinkernagel R.M., Hengartner H. IL-12 is not required for induction of type 1 cytokine responses in viral infections. J Immunol. 162:1999;965-973. Despite the critical role for IL-12 in resistance to many intracellular pathogens, this paper shows for the first time that IL-12-independent protective responses to LCMV and VSV can be generated.
-
(1999)
J Immunol
, vol.162
, pp. 965-973
-
-
Oxenius, A.1
Karrer, U.2
Zinkernagel, R.M.3
Hengartner, H.4
-
15
-
-
0033136323
-
+ T cell response by IFN-γ In IL-12-deficient mice during Toxoplasma gondii infection
-
+ T cell response by IFN-γ in IL-12-deficient mice during Toxoplasma gondii infection. J Immunol. 162:1999;5449-5454.
-
(1999)
J Immunol
, vol.162
, pp. 5449-5454
-
-
Ely, K.H.1
Kasper, L.H.2
Khan, I.A.3
-
16
-
-
0033583516
-
Two roads diverged: Interferon α/β- And interleukin 12-mediated pathways in promoting T cell interferon γ responses during viral infection
-
+ T cells during infection with LCMV but in their absence IL-12 becomes important in this process.
-
+ T cells during infection with LCMV but in their absence IL-12 becomes important in this process.
-
(1999)
J Exp Med
, vol.189
, pp. 1315-1328
-
-
Cousens, L.P.1
Peterson, R.2
Hsu, S.3
Dorner, A.4
Altman, J.D.5
Ahmed, R.6
Biron, C.A.7
-
17
-
-
0032535370
-
Inherited interleukin 12 deficiency in a child with bacille Calmette-Guerin and Salmonella enteritidis disseminated infection
-
Altare F., Lammas D., Revy P., Jouanguy E., Doffinger R., Lamhamedi S., Drysdale P., Scheel-Toellner D., Girdlestone J., Darbyshire P.et al. Inherited interleukin 12 deficiency in a child with bacille Calmette-Guerin and Salmonella enteritidis disseminated infection. J Clin Invest. 102:1998;2035-2040.
-
(1998)
J Clin Invest
, vol.102
, pp. 2035-2040
-
-
Altare, F.1
Lammas, D.2
Revy, P.3
Jouanguy, E.4
Doffinger, R.5
Lamhamedi, S.6
Drysdale, P.7
Scheel-Toellner, D.8
Girdlestone, J.9
Darbyshire, P.10
-
18
-
-
0032577295
-
Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients
-
de Jong R., Altare F., Haagen I-A., Elferink D.G., de Boer T., van Breda Vriesman P.J.C., Kabel P.J., Draaisma J.M.T., van Dissel J.I., Kroon F.P.et al. Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients. Science. 280:1998;1435-1438.
-
(1998)
Science
, vol.280
, pp. 1435-1438
-
-
De Jong, R.1
Altare, F.2
Haagen, I.-A.3
Elferink, D.G.4
De Boer, T.5
Van Breda Vriesman, P.J.C.6
Kabel, P.J.7
Draaisma, J.M.T.8
Van Dissel, J.I.9
Kroon, F.P.10
-
19
-
-
18244428735
-
Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency
-
Altare F., Durandy A., Lammas D., Emile J-F., Lamhamedi S., Le Deist F., Drysdale P., Jouanguy E., Doffinger R., Bernaudin F.et al. Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency. Science. 280:1998;1432-1435.
-
(1998)
Science
, vol.280
, pp. 1432-1435
-
-
Altare, F.1
Durandy, A.2
Lammas, D.3
Emile, J.-F.4
Lamhamedi, S.5
Le Deist, F.6
Drysdale, P.7
Jouanguy, E.8
Doffinger, R.9
Bernaudin, F.10
-
20
-
-
0032103249
-
Mutation in the signal-transducing chain of the interferon-gamma receptor and susceptibility to mycobacterial infection
-
Dorman S.E., Holland S.M. Mutation in the signal-transducing chain of the interferon-gamma receptor and susceptibility to mycobacterial infection. J Clin Invest. 101:1998;2364-2369.
-
(1998)
J Clin Invest
, vol.101
, pp. 2364-2369
-
-
Dorman, S.E.1
Holland, S.M.2
-
21
-
-
0033497350
-
Viral infections in interferon-gamma receptor deficiency
-
Dorman S.E., Uzel G., Roesler J., Bradley J.S., Bastian J., Billman G., King S., Filie A., Schermerhorn J., Holland S.M. Viral infections in interferon-gamma receptor deficiency. J Ped. 135:1999;640-643.
-
(1999)
J Ped
, vol.135
, pp. 640-643
-
-
Dorman, S.E.1
Uzel, G.2
Roesler, J.3
Bradley, J.S.4
Bastian, J.5
Billman, G.6
King, S.7
Filie, A.8
Schermerhorn, J.9
Holland, S.M.10
-
23
-
-
0031820396
-
Differential regulation of the interleukin-12 receptor during the innate immune response to Leishmania major
-
Jones D., Elloso M.M., Showe L., Williams D., Trinchieri G., Scott P. Differential regulation of the interleukin-12 receptor during the innate immune response to Leishmania major. Infect Immun. 66:1998;3818-3824.
-
(1998)
Infect Immun
, vol.66
, pp. 3818-3824
-
-
Jones, D.1
Elloso, M.M.2
Showe, L.3
Williams, D.4
Trinchieri, G.5
Scott, P.6
-
24
-
-
0033563135
-
IL-4- And IL-4 receptor deficient BALB/c mice reveal differences in susceptibility to Leishmania major parasite substrains
-
These studies illustrate that the role of IL-4 in susceptibility to L. major is dependent on the strain of parasite used.
-
Noben-Trauth N., Paul W.E., Sacks D.L. IL-4- and IL-4 receptor deficient BALB/c mice reveal differences in susceptibility to Leishmania major parasite substrains. J Immunol. 162:1999;6132-6140. These studies illustrate that the role of IL-4 in susceptibility to L. major is dependent on the strain of parasite used.
-
(1999)
J Immunol
, vol.162
, pp. 6132-6140
-
-
Noben-Trauth, N.1
Paul, W.E.2
Sacks, D.L.3
-
25
-
-
0033564686
-
Differences between IL-4- And IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signalling
-
Mohrs M., Ledermann B., Kohler G., Dorfmuller A., Gessner A., Brombacher F. Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signalling. J Immunol. 162:1999;7302-7308.
-
(1999)
J Immunol
, vol.162
, pp. 7302-7308
-
-
Mohrs, M.1
Ledermann, B.2
Kohler, G.3
Dorfmuller, A.4
Gessner, A.5
Brombacher, F.6
-
26
-
-
0033566955
-
BCL-6-deficient mice reveal an IL-4-independent, STAT6-dependent pathway that controls susceptibility to infection by Leishmania major
-
Dent A.L., Doherty T.M., Paul W.E., Sher A., Staudt L.M. BCL-6-deficient mice reveal an IL-4-independent, STAT6-dependent pathway that controls susceptibility to infection by Leishmania major. J Immunol. 163:1999;2098-2103.
-
(1999)
J Immunol
, vol.163
, pp. 2098-2103
-
-
Dent, A.L.1
Doherty, T.M.2
Paul, W.E.3
Sher, A.4
Staudt, L.M.5
-
27
-
-
0034141850
-
IL-13 is a susceptibility factor for Leishmania major infection
-
The authors use IL-13-transgenic and IL-13-deficient mice to show that IL-13 is an antagonist of protective Th1 responses during leishmaniasis.
-
Matthews D.J., Emson C.L., McKenzie G.J., Jolin H.E., Blackwell J.M., McKenzie A.N. IL-13 is a susceptibility factor for Leishmania major infection. J Immunol. 164:2000;1458-1462. The authors use IL-13-transgenic and IL-13-deficient mice to show that IL-13 is an antagonist of protective Th1 responses during leishmaniasis.
-
(2000)
J Immunol
, vol.164
, pp. 1458-1462
-
-
Matthews, D.J.1
Emson, C.L.2
McKenzie, G.J.3
Jolin, H.E.4
Blackwell, J.M.5
McKenzie, A.N.6
-
28
-
-
0032007351
-
IL-13, IL-4R alpha, and STAT6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis
-
Urban J.F., Noben-Trauth N., Donaldson D.D., Madden K.B., Morris S.C., Collins M., Finkelman F.D. IL-13, IL-4R alpha, and STAT6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity. 8:1998;255-264.
-
(1998)
Immunity
, vol.8
, pp. 255-264
-
-
Urban, J.F.1
Noben-Trauth, N.2
Donaldson, D.D.3
Madden, K.B.4
Morris, S.C.5
Collins, M.6
Finkelman, F.D.7
-
29
-
-
0033973582
-
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
-
The ability of IL-4 to signal through STAT6 is important for development of Th2 responses but there are STAT6-independent pathways that can also lead to Th2 development and this is associated with stable expression of GATA-3.
-
Ouyang W., Lohning M., Gao Z., Assenmacher M., Ranganath S., Radbruch A., Murphy K.M. Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity. 12:2000;27-37. The ability of IL-4 to signal through STAT6 is important for development of Th2 responses but there are STAT6-independent pathways that can also lead to Th2 development and this is associated with stable expression of GATA-3.
-
(2000)
Immunity
, vol.12
, pp. 27-37
-
-
Ouyang, W.1
Lohning, M.2
Gao, Z.3
Assenmacher, M.4
Ranganath, S.5
Radbruch, A.6
Murphy, K.M.7
-
30
-
-
0034162535
-
Stat6 regulation of in vivo IL-4 responses
-
Finkelman F.D., Morris S.C., Orekhova T., Mori M., Donaldson D., Reiner S.L., Reilly N.L., Schopf L., Urban J.F. Stat6 regulation of in vivo IL-4 responses. J Immunol. 164:2000;2303-2310.
-
(2000)
J Immunol
, vol.164
, pp. 2303-2310
-
-
Finkelman, F.D.1
Morris, S.C.2
Orekhova, T.3
Mori, M.4
Donaldson, D.5
Reiner, S.L.6
Reilly, N.L.7
Schopf, L.8
Urban, J.F.9
-
31
-
-
0032499678
-
T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function
-
Lohning M., Stroehmann A., Coyle A.J., Grogan J.L., Lin S., Gutierrez-Ramos J.C., Levinson D., Radbruch A., Kamradt T. T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc Nat Acad Sci USA. 95:1998;6930-6935.
-
(1998)
Proc Nat Acad Sci USA
, vol.95
, pp. 6930-6935
-
-
Lohning, M.1
Stroehmann, A.2
Coyle, A.J.3
Grogan, J.L.4
Lin, S.5
Gutierrez-Ramos, J.C.6
Levinson, D.7
Radbruch, A.8
Kamradt, T.9
-
32
-
-
18244418305
-
+ T cells from schistosome egg-induced granulomas: Analysis of Th cell cytokine coexpression ex vivo
-
+ T cells from schistosome egg-induced granulomas: analysis of Th cell cytokine coexpression ex vivo. J Immunol. 162:1999;3882-3889.
-
(1999)
J Immunol
, vol.162
, pp. 3882-3889
-
-
Lohning, M.1
Grogan, J.L.2
Coyle, A.J.3
Yazdanbakhsh, M.4
Meisel, C.5
Gutierrez-Ramos, J.C.6
Radbruch, A.7
Kamradt, T.8
-
33
-
-
2642610290
-
Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells
-
Xu D., Chan W.L., Leung B.P., Huang F., Wheeler R., Piedrafita D., Robinson J.H., Liew F.Y. Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. J Exp Med. 187:1998;787-794.
-
(1998)
J Exp Med
, vol.187
, pp. 787-794
-
-
Xu, D.1
Chan, W.L.2
Leung, B.P.3
Huang, F.4
Wheeler, R.5
Piedrafita, D.6
Robinson, J.H.7
Liew, F.Y.8
-
34
-
-
0031739697
-
CTLA4 (CD152) modulates the Th subset response and alters the course of experimental Leishmania major infection
-
Saha B., Chattopadhyay S., Germond R., Harlan D.M., Perrin P.J. CTLA4 (CD152) modulates the Th subset response and alters the course of experimental Leishmania major infection. Eur J Immunol. 28:1998;4213-4220.
-
(1998)
Eur J Immunol
, vol.28
, pp. 4213-4220
-
-
Saha, B.1
Chattopadhyay, S.2
Germond, R.3
Harlan, D.M.4
Perrin, P.J.5
-
35
-
-
0032746004
-
Interleukin-4-independent acceleration of cutaneous leishmaniasis in susceptible BALB/c mice following treatment with anti-CTLA4 antibody
-
Heinzel F.P., Maier R.A. Interleukin-4-independent acceleration of cutaneous leishmaniasis in susceptible BALB/c mice following treatment with anti-CTLA4 antibody. Infect Immun. 67:1999;6454-6460.
-
(1999)
Infect Immun
, vol.67
, pp. 6454-6460
-
-
Heinzel, F.P.1
Maier, R.A.2
-
36
-
-
0032532640
-
Blockade of CTLA-4 enhances host resistance to the intracellular pathogen, Leishmania donovani
-
Murphy M.L., Cotterell S.E., Gorak P.M., Engwerda C.R., Kaye P.M. Blockade of CTLA-4 enhances host resistance to the intracellular pathogen, Leishmania donovani. J Immunol. 161:1998;4153-4160.
-
(1998)
J Immunol
, vol.161
, pp. 4153-4160
-
-
Murphy, M.L.1
Cotterell, S.E.2
Gorak, P.M.3
Engwerda, C.R.4
Kaye, P.M.5
-
38
-
-
0033568303
-
The CD28/B7 interaction is not required for resistance to Toxoplasma gondii in the brain but contributes to the development of immunopathology
-
Reichmann G., Villegas E.N., Craig L., Peach R., Hunter C.A. The CD28/B7 interaction is not required for resistance to Toxoplasma gondii in the brain but contributes to the development of immunopathology. J Immunol. 163:1999;3354-3362.
-
(1999)
J Immunol
, vol.163
, pp. 3354-3362
-
-
Reichmann, G.1
Villegas, E.N.2
Craig, L.3
Peach, R.4
Hunter, C.A.5
-
39
-
-
0344614706
-
Critical role of CD28 in protective immunity against Salmonella typhimurium
-
Mittrucker H.W., Kohler A., Mak T.W., Kaufmann S.H. Critical role of CD28 in protective immunity against Salmonella typhimurium. J Immunol. 163:1999;6769-6776.
-
(1999)
J Immunol
, vol.163
, pp. 6769-6776
-
-
Mittrucker, H.W.1
Kohler, A.2
Mak, T.W.3
Kaufmann, S.H.4
-
40
-
-
0033590502
-
ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
-
Hutloff A., Dittrich A.M., Beier K.C., Eljaschewitsch B., Kraft R., Anagnostopoulos I., Kroczek R.A. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature. 397:1999;263-266.
-
(1999)
Nature
, vol.397
, pp. 263-266
-
-
Hutloff, A.1
Dittrich, A.M.2
Beier, K.C.3
Eljaschewitsch, B.4
Kraft, R.5
Anagnostopoulos, I.6
Kroczek, R.A.7
-
41
-
-
0033212778
-
B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFα
-
Swallow M.M., Wallin J.J., Sha W.C. B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFα Immunity. 11:1999;423-432.
-
(1999)
Immunity
, vol.11
, pp. 423-432
-
-
Swallow, M.M.1
Wallin, J.J.2
Sha, W.C.3
-
42
-
-
0033576707
-
T-cell co-stimulation through B7RP-1 and ICOS
-
This manuscript identifies B7RP-1 (B7h) and ICOS as a costimulatory pair distinct from the B7-CD28/CTLA-4 interactions.
-
Yoshinaga S.K., Whoriskey J.S., Khare S.D., Sarmiento U., Guo J., Horan T., Shih G., Zhang M., Coccia M.A., Kohno T.et al. T-cell co-stimulation through B7RP-1 and ICOS. Nature. 402:1999;827-832. This manuscript identifies B7RP-1 (B7h) and ICOS as a costimulatory pair distinct from the B7-CD28/CTLA-4 interactions.
-
(1999)
Nature
, vol.402
, pp. 827-832
-
-
Yoshinaga, S.K.1
Whoriskey, J.S.2
Khare, S.D.3
Sarmiento, U.4
Guo, J.5
Horan, T.6
Shih, G.7
Zhang, M.8
Coccia, M.A.9
Kohno, T.10
-
43
-
-
0032482356
-
Help for cytotoxic-T-cell responses is mediated by CD40 signalling
-
Bennett S.R.M., Carbone F.R., Karamalis F., Flavell R.A., Miller J.F.A.P., Heath W.R. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature. 393:1998;478-480.
-
(1998)
Nature
, vol.393
, pp. 478-480
-
-
Bennett, S.R.M.1
Carbone, F.R.2
Karamalis, F.3
Flavell, R.A.4
Miller, J.F.A.P.5
Heath, W.R.6
-
44
-
-
0032482474
-
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
-
Schoenberger S.P., Toes R.E.M., van der Voort E.I.H., Offringa R., Melief C.J.M. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature. 393:1998;480-483.
-
(1998)
Nature
, vol.393
, pp. 480-483
-
-
Schoenberger, S.P.1
Toes, R.E.M.2
Van Der Voort, E.I.H.3
Offringa, R.4
Melief, C.J.M.5
-
46
-
-
3643064537
-
CD40 ligand is pivotal to efficient control of virus replication in mice infected with lymphocytic choriomeningitis virus
-
Thomsen A.R., Nansen A., Christensen J.P., Andreasen S.O., Marker O. CD40 ligand is pivotal to efficient control of virus replication in mice infected with lymphocytic choriomeningitis virus. J Immunol. 161:1998;4583-4590.
-
(1998)
J Immunol
, vol.161
, pp. 4583-4590
-
-
Thomsen, A.R.1
Nansen, A.2
Christensen, J.P.3
Andreasen, S.O.4
Marker, O.5
-
48
-
-
0033152563
-
CD40-CD40 ligand interaction is central to cell-mediated immunity against Toxoplasma gondii: Patients with hyper IgM syndrome have a defective type 1 immune response that can be restored by soluble CD40 ligand trimer
-
Hyper-IgM patients are susceptible to T. gondii and peripheral-blood mononuclear cells from naive and infected patients have an impaired ability to make IL-12 and IFN-γ in response to this parasite.
-
Subauste C.S., Wessendarp M., Sorensen R.U., Leiva L.E. CD40-CD40 ligand interaction is central to cell-mediated immunity against Toxoplasma gondii: patients with hyper IgM syndrome have a defective type 1 immune response that can be restored by soluble CD40 ligand trimer. J Immunol. 162:1999;6690-6700. Hyper-IgM patients are susceptible to T. gondii and peripheral-blood mononuclear cells from naive and infected patients have an impaired ability to make IL-12 and IFN-γ in response to this parasite.
-
(1999)
J Immunol
, vol.162
, pp. 6690-6700
-
-
Subauste, C.S.1
Wessendarp, M.2
Sorensen, R.U.3
Leiva, L.E.4
-
49
-
-
0033560934
-
Defects of T-cell effector function and post-thymic maturation in X-linked hyper-IgM syndrome
-
Jain A., Atkinson T.P., Lipsky P.E., Slater J.E., Nelson D.L., Strober W. Defects of T-cell effector function and post-thymic maturation in X-linked hyper-IgM syndrome. J Clin Invest. 103:1999;1151-1158.
-
(1999)
J Clin Invest
, vol.103
, pp. 1151-1158
-
-
Jain, A.1
Atkinson, T.P.2
Lipsky, P.E.3
Slater, J.E.4
Nelson, D.L.5
Strober, W.6
-
50
-
-
0032711836
-
4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses
-
Tan J.T., Whitmire J.K., Ahmed R., Pearson T.C., Larsen C.P. 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses. J Immunol. 163:1999;4859-4868.
-
(1999)
J Immunol
, vol.163
, pp. 4859-4868
-
-
Tan, J.T.1
Whitmire, J.K.2
Ahmed, R.3
Pearson, T.C.4
Larsen, C.P.5
-
51
-
-
0032754036
-
Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus
-
DeBenedette M.A., Wen T., Bachmann M.F., Ohashi P.S., Barber B.H., Stocking K.L., Peschon J.J., Watts T.H. Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus. J Immunol. 163:1999;4833-4841.
-
(1999)
J Immunol
, vol.163
, pp. 4833-4841
-
-
Debenedette, M.A.1
Wen, T.2
Bachmann, M.F.3
Ohashi, P.S.4
Barber, B.H.5
Stocking, K.L.6
Peschon, J.J.7
Watts, T.H.8
-
52
-
-
0344286707
-
Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40)
-
Pippig S.D., Pena-Rossi C., Long J., Godfrey W.R., Fowell D.J., Reiner S.L., Birkeland M.L., Locksley R.M., Barclay A.N., Killeen N. Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40). J Immunol. 163:1999;6520-6529.
-
(1999)
J Immunol
, vol.163
, pp. 6520-6529
-
-
Pippig, S.D.1
Pena-Rossi, C.2
Long, J.3
Godfrey, W.R.4
Fowell, D.J.5
Reiner, S.L.6
Birkeland, M.L.7
Locksley, R.M.8
Barclay, A.N.9
Killeen, N.10
-
53
-
-
0033427047
-
OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL responses after virus infection
-
Kopf M., Ruedl C., Schmitz N., Gallimore A., Lefrang K., Ecabert B., Odermatt B., Bachmann M.F. OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL responses after virus infection. Immunity. 11:1999;699-708.
-
(1999)
Immunity
, vol.11
, pp. 699-708
-
-
Kopf, M.1
Ruedl, C.2
Schmitz, N.3
Gallimore, A.4
Lefrang, K.5
Ecabert, B.6
Odermatt, B.7
Bachmann, M.F.8
-
54
-
-
0034677124
-
Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental Leishmaniasis
-
Although other studies suggest no role for the OX40-OX40L interaction in resistance to L. major, these authors show that susceptible mice treated with anti-OX40L develop resistance to this parasite.
-
Akiba H., Miyahira Y., Atsuta M., Takeda K., Nohara C., Futagawa T., Matsuda H., Aoki T., Yagita H., Okumura K. Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental Leishmaniasis. J Exp Med. 191:2000;375-380. Although other studies suggest no role for the OX40-OX40L interaction in resistance to L. major, these authors show that susceptible mice treated with anti-OX40L develop resistance to this parasite.
-
(2000)
J Exp Med
, vol.191
, pp. 375-380
-
-
Akiba, H.1
Miyahira, Y.2
Atsuta, M.3
Takeda, K.4
Nohara, C.5
Futagawa, T.6
Matsuda, H.7
Aoki, T.8
Yagita, H.9
Okumura, K.10
-
55
-
-
0033548496
-
Linear differentiation of cytotoxic effectors into memory T lymphocytes
-
Opferman J.T., Ober B.T., Ashton-Rickardt P.G. Linear differentiation of cytotoxic effectors into memory T lymphocytes. Science. 283:1999;1745-1748.
-
(1999)
Science
, vol.283
, pp. 1745-1748
-
-
Opferman, J.T.1
Ober, B.T.2
Ashton-Rickardt, P.G.3
-
56
-
-
0033557173
-
T cell affinity maturation by selective expansion during infection
-
This paper shows that following a primary infection with L. monocytogenes there is a diverse repertoire of specific memory cells; rechallenge leads to selection of the higher-affinity T cells and a narrowing of this repertoire.
-
Busch D.H., Pamer E.G. T cell affinity maturation by selective expansion during infection. J Exp Med. 189:1999;701-710. This paper shows that following a primary infection with L. monocytogenes there is a diverse repertoire of specific memory cells; rechallenge leads to selection of the higher-affinity T cells and a narrowing of this repertoire.
-
(1999)
J Exp Med
, vol.189
, pp. 701-710
-
-
Busch, D.H.1
Pamer, E.G.2
-
57
-
-
0033118739
-
A kinetic basis for T cell receptor repertoire selection during an immune response
-
Savage P.A., Boniface J.J., Davis M.M. A kinetic basis for T cell receptor repertoire selection during an immune response. Immunity. 10:1999;485-492.
-
(1999)
Immunity
, vol.10
, pp. 485-492
-
-
Savage, P.A.1
Boniface, J.J.2
Davis, M.M.3
-
58
-
-
0032720640
-
Persistence of memory CD8 T cells in MHC class I-deficient mice
-
Murali-Krishna K., Lau L.L., Sambhara S., Lemonnier F., Altman J., Ahmed R. Persistence of memory CD8 T cells in MHC class I-deficient mice. Science. 286:1999;1377-1381.
-
(1999)
Science
, vol.286
, pp. 1377-1381
-
-
Murali-Krishna, K.1
Lau, L.L.2
Sambhara, S.3
Lemonnier, F.4
Altman, J.5
Ahmed, R.6
-
59
-
-
0032589687
-
Class II-independent generation of CD4 memory T cells from effectors
-
Swain S.L., Hu H., Huston G. Class II-independent generation of CD4 memory T cells from effectors. Science. 286:1999;1381-1383.
-
(1999)
Science
, vol.286
, pp. 1381-1383
-
-
Swain, S.L.1
Hu, H.2
Huston, G.3
-
60
-
-
0033451199
-
Attrition of T cell memory: Selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses
-
This paper shows, for the first time, that stable memory response for one viral infection can be decreased by heterologous viral infections although cross-reactive responses are maintained.
-
Selin L.K., Lin M.Y., Kraemer K.A., Pardoll D.M., Schneck J.P., Varga S.M., Santolucito P.A., Pinto A.K., Welsh R.M. Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses. Immunity. 11:1999;733-742. This paper shows, for the first time, that stable memory response for one viral infection can be decreased by heterologous viral infections although cross-reactive responses are maintained.
-
(1999)
Immunity
, vol.11
, pp. 733-742
-
-
Selin, L.K.1
Lin, M.Y.2
Kraemer, K.A.3
Pardoll, D.M.4
Schneck, J.P.5
Varga, S.M.6
Santolucito, P.A.7
Pinto, A.K.8
Welsh, R.M.9
-
61
-
-
0032853312
-
+ T cell mediated immunity in mice infected with a vaccine strain of Toxoplasma gondii
-
This paper shows, for the first time, that although vaccination-induced immunity to T. gondii declines with time, administration of IL-15 can augment or delay the loss of protective memory responses.
-
+ T cell mediated immunity in mice infected with a vaccine strain of Toxoplasma gondii. J Immunol. 163:1999;4503-4509. This paper shows, for the first time, that although vaccination-induced immunity to T. gondii declines with time, administration of IL-15 can augment or delay the loss of protective memory responses.
-
(1999)
J Immunol
, vol.163
, pp. 4503-4509
-
-
Khan, I.A.1
Casciotti, L.2
-
63
-
-
0031757985
-
Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection
-
An important study that documents a requirement for IL-12 in the maintenance of vaccination-induced immunity to L. major.
-
Gurunathan S., Prussin C., Sacks D.L., Seder R.A. Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection. Nature Med. 4:1998;1409-1415. An important study that documents a requirement for IL-12 in the maintenance of vaccination-induced immunity to L. major.
-
(1998)
Nature Med
, vol.4
, pp. 1409-1415
-
-
Gurunathan, S.1
Prussin, C.2
Sacks, D.L.3
Seder, R.A.4
-
64
-
-
1442342360
-
Following the development of a CD4 T cell response in vivo: From activation to memory formation
-
L : Bcl-2 compared with naive T cells.
-
L : Bcl-2 compared with naive T cells.
-
(1999)
Immunity
, vol.11
, pp. 163-171
-
-
Garcia, S.1
Disanto, J.2
Stockinger, B.3
-
65
-
-
0033166538
-
Dealing from the evolutionary pawnshop: How lymphocytes make decisions
-
Reiner S.L., Seder R.A. Dealing from the evolutionary pawnshop: how lymphocytes make decisions. Immunity. 11:1999;1-10.
-
(1999)
Immunity
, vol.11
, pp. 1-10
-
-
Reiner, S.L.1
Seder, R.A.2
-
66
-
-
0034040798
-
Genetically resisitant mice lacking IL-18 gene develop Th1 response and control cutaneous Leishmania major infection
-
in press.
-
Monteforte G.M., Takeda K., Rodriguez-Sosa M., Akira S., David J.R., Satoskar A.R. Genetically resisitant mice lacking IL-18 gene develop Th1 response and control cutaneous Leishmania major infection. J Immunol. 2000;. in press.
-
(2000)
J Immunol
-
-
Monteforte, G.M.1
Takeda, K.2
Rodriguez-Sosa, M.3
Akira, S.4
David, J.R.5
Satoskar, A.R.6
-
67
-
-
0034099407
-
Potentiality of interleukin-18 as a useful reagent for treatment and prevention of Leishmania major infection
-
Ohkusu K., Yoshimoto T., Takeda K., Ogura T., Kashiwamura S., Iwakura Y., Akira S., Okamura H., Nakanishi K. Potentiality of interleukin-18 as a useful reagent for treatment and prevention of Leishmania major infection. Infect Immun. 68:2000;1449-2456.
-
(2000)
Infect Immun
, vol.68
, pp. 1449-2456
-
-
Ohkusu, K.1
Yoshimoto, T.2
Takeda, K.3
Ogura, T.4
Kashiwamura, S.5
Iwakura, Y.6
Akira, S.7
Okamura, H.8
Nakanishi, K.9
-
69
-
-
0034661678
-
IL-12 is required to maintain a Th1 response during Leishmania major infection
-
in press.
-
Park A., Hondowicz B., Scott P. IL-12 is required to maintain a Th1 response during Leishmania major infection. J Immunol. 2000;. in press.
-
(2000)
J Immunol
-
-
Park, A.1
Hondowicz, B.2
Scott, P.3
-
70
-
-
0034662258
-
IL-12 is required for the maintenance of IFN-γ-production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii
-
in press.
-
Yap G., Pesin M., Sher A. IL-12 is required for the maintenance of IFN-γ-production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii. J Immunol. 2000;. in press.
-
(2000)
J Immunol
-
-
Yap, G.1
Pesin, M.2
Sher, A.3
|