Attrition of T cell memory: Selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses

Immunity

Volumn 11, Issue 6, 1999, Pages 733-742

  Selin, Liisa K ^a   Lin, Meei Y ^a   Kraemer, Kristy A ^b   Pardoll, Drew M ^b   Schneck, Jonathan P ^b   Varga, Steven M ^a   Santolucito, Paul A ^a   Pinto, Amelia K ^a   Welsh, Raymond M ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN G1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL COUNT; CELL FUNCTION; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOTOXICITY; IMMUNE SYSTEM; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MALE; MEMORY CELL; MOUSE; NONHUMAN; PICHINDE ARENAVIRUS; PRIORITY JOURNAL; T LYMPHOCYTE; VACCINIA VIRUS; VIRUS INFECTION;

EID: 0033451199     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80147-8     Document Type: Article

References (35)

1. Altman, J.D., Moss, P.A.H., Goulder, P.J.R., Barouch, D.H., McHeyzer-Williams, M.G., Bell, J.I., McMichael, A.J., and Davis, M.M. (1996). Phenotypic analysis of antigen-specific T lymphocytes. Science 274, 94-96.
2. Attaya, M., Jameson, S., Martinez, C.K., Hermel, E., Aldrich, C., Forman, J., Fischer-Lindahl, K., Bevan, M.J., and Monaco, J.J. (1992). Ham-2 corrects the class I antigen-processing defect in RMA-S cells. Nature 355, 647-649.
3. Bukowski, J.F., Woda, B.A., Habu, S., Okumura, K., and Welsh, R.M. (1983). Natural killer cell depletion enhances virus synthesis and virus-induced hepatitis in vivo. J. Immunol. 131, 1531-1538.
4. Butz, E.A., and Bevan, M.J. (1998). Massive expansion of antigen-specific CD8+ T cells during an acute virus infection. Immunity 8, 167-175.
5. + T cells during the primary immune response to Epstein-Barr virus in vivo. J. Exp. Med. 187, 1395-1402.
6. Dal Porto, J., Johansen, T.E., Catipovic, B., Parfiit, D.J., Tuveson, D., Gether, U., Kozlowski, S., Fearon, D.T., and Schneck, J.P. (1993). A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations. Proc. Natl. Acad. Sci. USA 90, 6671-6675.
7. + T-cell mechanisms in the control of respiratory virus infections. Immunol. Rev. 159, 105-117.
8. + T cells in primary and secondary influenza pneumonia. Immunity 8, 683-691.
9. + T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients. Proc. Natl. Acad. Sci. USA 95, 7568-7573.
10. Hou, S., Hyland, L., Ryan, W., Portner, A., and Doherty, P.C. (1994). Virus-specific CD8+ T-cell memory determined by clonal burst size. Nature 369, 652-654.
11. b molecules is controlled by dominant negative elements at peptide non-anchor residues. Implications for peptide selection and presentation. J. Biol. Chem. 271, 17829-17836.
12. Lau, L.L., Jamieson, B.D., Somasundaram, T., and Ahmed, R. (1994). Cytotoxic T-cell memory without antigen. Nature 369, 648-652.
13. Lin, M.Y., and Welsh, R.M. (1998). Analysis of the stability of T cell receptor (TCR) repertoire usage during lymphocytic choriomeningitis virus (LCMV) infection of mice. J. Exp. Med. 188, 1993-2005.
14. Mason, D. (1998). A very high level of crossreactivity is an essential feature of the T cell repertoire. Immunol. Today 19, 395-404.
15. Mullbacher, A. (1994). The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen. J. Exp. Med. 179, 317-321.
16. Murali-Krishna, K., Altman, J.D., Suresh, M., Sourdive, D.J.D., Zajac, A.J., Miller, J.D., Slansky, J., and Ahmed, R. (1998). Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection. Immunity 8, 177-187.
17. Oehen, S., Walder, H., Kundig, T.M., Hengartner, H., and Zinkernagel, R.M. (1992). Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen. J. Exp. Med. 176, 1273-1281.
18. Oldstone, M.B., Lewicki, H., Borrow, P., Hudrisier, D., and Gairin, J.E. (1995). Discriminated selection among viral peptides with the appropriate anchor residues: Implications for the size of the cytotoxic T-lymphocyte repertoire and control of viral infection. J. Virol. 69, 7423-7429.
19. + T cells upon acute versus persistent viral infection. Immunity 9, 449-457.
20. Pannetier, C., Cochet, M., Darche, S., Casrouge, A., Zoller, M., and Kourilisky, P. (1993). The sizes of the CDR3 hypervariable regions of the murine T-cell receptor β chains vary as a function of the recombined germ-line segments. Proc. Natl. Acad. Sci. USA 90, 4319-4323.
21. Pross, H.F., Baines, M.G., Rubin, P., Shragge, P., and Paterson, M. S. (1981). Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells. J. Clin. Immunol. 1, 51-63.
22. Selin, L.K., and Welsh, R.M. (1994). Specificity and editing (by apoptosis) of the CD8+ cytotoxic T lymphocyte response during viral infections. Curr. Opin. Immun. 6, 553-559.
23. Selin, L.K., and Welsh, R.M. (1997). Cytolytically active memory CTL present in lymphocytic choriomeningitis virus-immune mice after clearance of virus infection. J. Immunol. 158, 5366-5373.
24. Selin, L.K., Nahill, S.R., and Welsh, R.M. (1994). Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses. J. Exp. Med. 179, 1933-1943.
25. Selin, L.K., Vergilis, K., Welsh, R.M., and Nahill, S.R. (1996). Reduction of otherwise remarkably stable virus-specific cytotoxic T lymphocyte memory by heterologous viral infections. J. Exp. Med. 183, 2489-2499.
26. Selin, L.K., Varga, S.M., Wong, I.C., and Welsh, R.M. (1998). Protective heterologous antiviral immunity and enhanced immunopathogenesis mediated by memory T cell populations. J. Exp. Med. 188, 1705-1715.
27. Tanaka, Y., and Tevethia, S.S. (1988). In vitro selection of SV40 antigen epitope loss variants by site-specific cytotoxic T lymphocyte clones. J. Immunol. 140, 4348-4354.
28. + T cell frequencies from acute infection into long term memory. J. Immunol. 161, 367-374.
29. + T cells during acute infection with lymphocytic choriomeningitis virus. J. Immunol. 161, 3215-3218.
30. Welsh, R.M., and McNally, J.M. (1999). Immune deficiency, immune silencing, and clonal exhaustion of T cell responses during viral infections. Curr. Opin. Microbiol. 2, 382-387.
31. Welsh, R.M., Lampert, P.W., Burner, P.A., and Oldstone, M.B.A. (1976). Antibody-complement interactions with purified lymphocytic choriomeningitis virus. Virology 73, 59-71.
32. Welsh, R.M., Lin, M.-Y., Lohman, B.L., Varga, S.M., Zarozinski, C.C., and Selin, L.K. (1997). Alpha-beta and gamma-delta T-cell networks and their roles in natural resistance to viral infections. Immunol. Rev. 159, 79-93.
33. Yang, H., Dundon, P.L., Nahill, S.R., and Welsh, R.M. (1989). Virus-induced polyclonal cytotoxic T lymphocyte stimulation. J. Immunol. 142, 1710-1718.
34. Zajac, A.J., Blattman, J.N., Murali-Krishna, K., Sourdive, D.J.D., Suresh, M., Altman, J.D., and Ahmed, R. (1998). Viral immune evasion due to persistence of activated T cells without effector function. J. Exp. Med. 188, 2205-2213.
35. Zarozinski, C.C., and Welsh, R.M. (1997). Minimal bystander activation of CD8 T cells during the virus-induced polyclonal T cell response. J. Exp. Med. 185, 1629-1639.