An analysis of the catalytic cycle of HIV-1 reverse transcriptase: Opportunities for chemotherapeutic intervention based on enzyme inhibition

Current Pharmaceutical Design

Volumn 6, Issue 5, 2000, Pages 547-567

  Furman, Phillip A ^a   Painter, George R ^a   Anderson, Karen S ^b  

^a Triangle Pharmaceuticals   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYADENOSINE TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; LAMIVUDINE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; THYMIDINE TRIPHOSPHATE; TRANSFER RNA; ZIDOVUDINE; ZIDOVUDINE 5' TRIPHOSPHATE;

ALLOSTERISM; BINDING AFFINITY; CATALYSIS; DRUG CONFORMATION; DRUG MECHANISM; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; REVIEW; VIRUS REPLICATION;

EID: 0034123317     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612003400777     Document Type: Review

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