Pre-steady-state kinetic characterization of wild type and 3'-azido-3'- deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: Implication of RNA directed DNA polymerization in the mechanism of AZT resistance

Biochemistry

Volumn 36, Issue 46, 1997, Pages 14064-14070

  Kerr, Stephen G ^a,b   Anderson, Karen S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; DNA REPLICATION; ENZYME KINETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; VIRUS ISOLATION;

ANTI-HIV AGENTS; DRUG RESISTANCE; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; KINETICS; MUTATION; REVERSE TRANSCRIPTASE INHIBITORS; RIBONUCLEASE H, CALF THYMUS; THYMIDINE MONOPHOSPHATE; THYMINE NUCLEOTIDES; ZIDOVUDINE;

EID: 0030703245     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9713862     Document Type: Article

References (41)

1. Anderson, K. S., Sikorski, J. A., Johnson, K. A. (1988) Biochemistry 27, 1604-1610.
2. Avramis, V. I., Kwock, R., Solorzano, M. M., & Gomperts, E. (1993) J. Acquir. Immune Defic. Syndr. 6, 1287-1296.
3. Barre-Sinoussi, F., Chermann, J. C., Rey, F., Nugeyre, M. T., Chamaret, S., Gruest, J., Dauget, C., Axler-Blin, C., Vezinet-Brun, F., Rouzious, C., Rozenbaum, W., & Montagnier, L. (1983) Science 220, 868-871.
4. Boyer, P. L., Tantillo, C., Jacobo-Molina, A., Nanni, R. G., Ding, J., Arnold, E., & Hughes, S. H. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 4882-4886.
5. Caliendo, A., Savara, A., An, D., DeVore, K., Kaplan, J., & D'Aquila, R. (1996) J. Virol. 70, 2146-2153.
6. Carroll, S. S., Geib, J., Olsen, D. B., Stahlhut, M., Shafer, J. A., & Kuo, L. C. (1994) Biochemistry 33, 2113-2120.
7. DeClercq, E. (1995) J. Med. Chem. 38, 2491-2517.
8. Divita, G., Müller, B., Immendorfer, U., Gautel, M., Rittinger, K., Restle, T., & Goody, R. S. (1993) Biochemistry 32, 7966-7971.
9. Furman, P. A., Fyfe, J. A., St. Clair, M. H., Weinhold, K., Rideout, J. L., Freeman, G. A., Nusinoff-Lehrman, S., Bolognesi, D. P., Broder, S., Mitsuya, H., & Barry, D. W. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 8333-8337.
10. Goody, R. S., Müller, B., and Restle, T. (1991) FEBS Lett. 1, 1-5.
11. Hoffman, A. D., Banapour, B., & Levy, J. A. (1985) Virology 147, 326-335.
12. Hsieh, J.-C., Zinnen, S., & Modrich, P. (1993) J. Biol. Chem. 268, 24607-24613.
13. Jacobo-Molina, A., Ding, J., Nanni, R. G., Clark, A. D., Jr, Lu, X., Tantillo C., Williams, R. L., Kamer, G., Ferris, A. L., Clark, P., Hizi, A., Hughes, S. H., & Arnold, E. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 3092-3096.
14. Jacobsson, B., Britton, S., He, Q., Karlsson, A., & Eriksson, S. (1995) AIDS Res. Hum. Retroviruses 11, 805-811.
15. Johnson, K. A. (1986) Methods Enzymol. 134, 677-705.
16. Johnson, K. A. (1992) The Enzymes 20, 1-1.
17. Johnson, K. A. (1993) Annu. Rev. Biochem. 62, 685-713.
18. Kati, W. M., Johnson, K. A., Jerva, L. F., & Anderson, K. S. (1992) J. Biol. Chem. 267, 25988-25997.
19. Kellam, P., Boucher, C. A. B., & Larder, B. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 1934-1938.
20. Kerr, S., & Anderson, K. (1997) Biochemistry, 36, 14056-14063.
21. Kohlstaedt, L. A., Wang, J., Friedman, J. M., Rice, P. A., & Steitz, T. A. (1992) Science 256, 1783-1790.
22. Lacey, S. F., Reardon, J. E., Furfine, E. S., Kunkel, T. A., Bebenek, K., Eckert, K. A., Kemp, S. D., & Larder, B. A. (1992) J. Biol. Chem. 267, 15789-15794
23. Larder, B. A. (1994) J. Gen. Virol. 75, 951-957.
24. Larder, B. A., Darby, G., & Richman, D. D. (1989) Science 243, 1731-1734.
25. Larder, B. A., & Kemp, S. D. (1989) Science 246, 1155-1158.
26. Larder, B. A., Kellam, P., & Kemp, S. D. (1991) AIDS 5, 137-144.
27. Mazumder, A., Cooney, D., Agbaria, R., Gupta, M., & Pommier, Y. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 5771-5775.
28. Mitsuya, H., Weinhold, K. J., Furman, P. A., St. Clair, M. H., Nusinoff-Lehrman, S., Gallo, R. C., Bolognesi, D., Barry, D. W., & Broder, S. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 7096-7100.
29. Müller, B., Restle, T., Reinstein, J., and Goody, R. S. (1991) Biochemistry 30, 3709-3715.
30. Popovic, M., Sarngadharan, M. G., Read, E., & Gallo, R. C. (1984) Science 224, 497-500.
31. Reardon, J. E., & Miller, W. H. (1990) J. Biol. Chem. 265, 20302-20307.
32. Reardon, J. E. (1992) Biochemistry 31, 4473-4479.
33. Reardon, J. E. (1993) J. Biol. Chem. 268, 8743-8751.
34. Rey, M. A., Spire, B., Dormont, D., Barre-Sinoussi, F., Montagnier, L., & Chermann, J. C. (1984) Biochem. Biophys. Res. Commun. 121, 126-133.
35. Richman, D. D. (1993) Annu. Rev. Pharmacol. Toxicol. 32, 149-164.
36. Rittinger K., Divita, G., & Goody, R. S. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 8046-8049.
37. Spence, R. A., Kati, W. M., Anderson, K. S., & Johnson, K. A. (1995) Science 267, 988-993.
38. Stahlhut, M., Li, Y., Condra, J. H., Fu, J., Gotlib, L. Graham, D. J., & Olsen, D. (1994) Protein Expression Purific. 6, 614-621.
39. St. Clair, M. H., Richards, C. A., Spector, T., Weinhold, K. J., Miller, W. H., Langlios, A. J., & Furman, P. A. (1981) Antimicrob. Agents Chemother. 31, 1972-1977.
40. Tantillo, C., Ding, J., Jacobo-Molina, A., Nanni, R. G., Boyer, P. L., Hughes, S. H., Pauwels, R., Andries, K., Janssen, P. A., & Arnold, E. (1994) J. Mol. Biol. 243, 369-387
41. Wu, S., Liu, X., Solorzano, M. M., Kwock, R., & Avramis, V. I. (1995) J. Acquir. Immune Defic. Syndr. 8, 1-9.