Modulation effects of cyclosporine on etoposide pharmacokinetics and CNS distribution in the rat utilizing microdialysis

Biochemical Pharmacology

Volumn 51, Issue 7, 1996, Pages 987-992

  Burgio, David E ^a   Gosland, Michael P ^a,b,c   McNamara, Patrick J ^a,c,d  

^a University of Kentucky   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d 433 College of Pharmacy Building   (United States)

Author keywords

central nervous system (CNS); etoposide; microdialysis; multidrug resistance; P glycoprotein; pharmacokinetics

Indexed keywords

CYCLOSPORIN; CYCLOSPORIN A; ETOPOSIDE; MULTIDRUG RESISTANCE REVERSING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG PROTEIN BINDING; INTRAVENOUS DRUG ADMINISTRATION; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; STEADY STATE; TISSUE DISTRIBUTION;

EID: 0029940587     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(95)02437-9     Document Type: Article

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