Twenty years of programmed modifications of the mouse genome: Revolution in the genetic approach of mammalian biology;Vingt ans d'interventions deliberees sur le genome de la souris. Une revolution dans l'approche genetique de la biologie des mammiferes

Medecine/Sciences

Volumn 16, Issue 1, 2000, Pages 31-42

  Babinet, Charles ^a   Cohen Tannoudji, Michel ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

CELL CULTURE; CHROMOSOME; CHROMOSOME DELETION; CHROMOSOME DUPLICATION; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; DNA MODIFICATION; DNA RECOMBINATION; GENE DELETION; GENE FUNCTION; GENE INACTIVATION; GENE INSERTION; GENE MUTATION; GENE REPLICATION; GENE TARGETING; GENOME; GERM LINE; KNOCKOUT GENE; LETHALITY; MOLECULAR CLONING; MOUSE; NONHUMAN; POINT MUTATION; REVIEW; STEM CELL;

ANIMALIA; MAMMALIA;

EID: 0033972434     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.4267/10608/1499     Document Type: Review

References (62)

1. Avery OT, MacLeod CM, McCarty M. Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a desoxyribonucleic acid fraction isolated from Pneumococcus type III. J Exp Med 1944; 79: 137-58.
2. Capecchi MR. Altering the genome by homologous recombination. Science 1989; 244: 1288-92.
3. Smithies O. Animal models of human genetic diseases. Trends Genet 1993; 9: 112-6.
4. Gardner RL, Brook FA. Reflections on the biology of embryonic stem (ES) cells. Int J Dev Biol 1997; 41: 235-43.
5. Smithies O, Gregg RG, Boggs SS, Koralewski MA, Kucherlapati RS. Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination. Nature 1985; 317: 230-4.
6. Wong EA, Capecchi MR. Analysis of homologous recombination in cultured mammalian cells in transient expression and stable transformation assays. Somat Cell Mol Genet 1986; 12: 63-72.
7. Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 1981; 78: 7634-8.
8. Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981; 292: 154-6.
9. Gossler A, Doetschman T, Korn R, Serfling E, Kemler R. Transgenesis by means of blastocyst-derived embryonic stem cell lines. Proc Natl Acad Sci USA 1986; 83: 9065-9.
10. Robertson E, Bradley A, Kuehn M, Evans M. Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector. Nature 1986; 323: 445-8.
11. Doetschman T, Gregg RG, Maeda N, et al. Targetted correction of a mutant HPRT gene in mouse embryonic stem cells. Nature 1987; 330: 576-8.
12. Thomas KR, Capecchi MR. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 1987; 51: 503-12.
13. The Transgenic/Targeted Mutation Database, http://tbase.jax.org/.
14. Banbury Conference on genetic background in mice. Mutant mice and neuroscience: recommendations concerning genetic background. Neuron 1997; 19: 755-9.
15. Rudnicki MA, Jaenisch R. The MyoD family of transcription factors and skeletal myogenesis. Bioessays 1995; 17: 203-9.
16. Horan GS, Ramirez SR, Featherstone MS, et al. Compound mutants for the paralogous hoxa-4, hoxb-4 and hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed. Genes Dev 1995; 9: 1667-77.
17. Li Z, Mericskay M, Agbulut O, et al. Desmin is essential for the tensile strength and integrity of myofibrils but not for myogenic commitment, differentiation, and fusion of skeletal muscle. J Cell Biol 1997; 139: 129-44.
18. Schneider-Maunoury S, Topilko P, Seitandou T, et al. Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain. Cell 1993; 75: 1199-214.
19. Tajbakhsh S, Rocancourt D, Buckingham M. Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice. Nature 1996; 384: 266-70.
20. Hanks M, Wurst W, Anson-Cartwright L, Auerbach AB, Joyner AL. Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science 1995; 269: 679-82.
21. Hanks MC, Loomis CA, Harris E, et al. Drosophila engrailed can substitute for mouse Engrailed1 function in mid-hindbrain, but not limb development. Development 1998; 125: 4521-30.
22. Saga Y. Genetic rescue of segmentation defect in MesP2-deficient mice by MesP1 gene replacement. Mech Dev 1998; 75: 53-66.
23. Wang Y, Jaenisch R. Myogenin can substitute for Myf5 in promoting myogenesis but less efficiently. Development 1997; 124: 2507-13.
24. Suda Y, Nakabayashi J, Matsuo I, Aizawa S. Functional equivalency between Otx2 and Otx1 in development of the rostral head. Development 1999; 126: 743-57.
25. Geng Y, Whoriskey W, Park MY, et al. Rescue of cyclin D1 deficiency by knockin cyclin E. Cell 1999; 97: 767-77.
26. -/- divergent phenotypes. Development 1999; 126: 1417-26.
27. Kerem B, Rommens JM, Buchanan JA, et al. Identification of the cystic fibrosis gene: genetic analysis. Science 1989; 245: 1073-80.
28. Fiering S, Bender MA, Groudine M. Analysis of mammalian cis-regulatory DNA elements by homologous recombination. Meth Enzymol 1999; 306: 42-66.
29. Meyers EN, Lewandoski M, Martin GR. An Fgf-8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat Genet 1998; 18: 136-41.
30. Moore RC, Hope J, McBride PA, et al. Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent. Nat Genet 1998; 18: 118-24.
31. Cohen-Tannoudji M, Babinet C. Beyond «knock-out» mice: new perspectives for the programmed modification of the mammalian genome. Mol Hum Reprod 1998; 4: 929-38.
32. Sauer B. Inducible gene targeting in mice using the Cre/lox system. Methods 1998; 14: 381-92.
33. Kilby NJ, Snaith MR, Murray JAH. Site-specific recombinases: tools for genome engineering. Trends Genet 1993; 9: 413-21.
34. Sauer B, Henderson N. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc Natl Acad Sci USA 1988; 85: 5166-70.
35. Bode VC. Ethylnitrosourea mutagenesis and the isolation of mutant alleles for specific genes located in the T region of mouse chromosome 17. Genetics 1984; 108: 457-70.
36. Brown SD, Peters J. Combining mutagenesis and genomics in the mouse-closing the phenotype gap. Trends Genet 1996; 12: 433-5.
37. Justice MJ, Zheng B, Woychik RP, Bradley A. Using targeted large deletions and high-efficiency N-ethyl-N- nitrosourea mutagenesis for functional analyses of the mammalian genome. Methods 1997; 13: 423-36.
38. Ramirez-Solis R, Liu P, Bradley A. Chromosome engineering in mice. Nature 1995; 378: 720-4.
39. You Y, Bergstrom R, Klemm M, et al. Chromosomal deletion complexes in mice by radiation of embryonic stem cells. Nat Genet 1997; 15: 285-8.
40. Vidal F, Sage J, Cuzin F, Rassoulzadegan M. Cre expression in primary spermatocytes: a tool for genetic engineering of the germ line. Mol Reprod Dev 1998; 51: 274-80.
41. Herault Y, Rassoulzadegan M, Cuzin F, Duboule D. Engineering chromosomes in mice through targeted meiotic recombination (TAMERE). Nat Genet 1998; 20: 381-4.
42. Gu H, Marth JD, Orban PC, Mossmann H, Rajewsky K. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 1994; 265: 103-6.
43. Xu X, Wagner KU, Larson D, et al. Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nat Genet 1999; 22: 37-43.
44. Shibata H, Toyama K, Shioya H, et al. Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. Science 1997; 278: 120-3.
45. Kulkarni RN Bruning JC, Winnay JN, et al. Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 1999; 96: 329-39.
46. Tsien JZ, Huerta PT, Tonegawa S. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 1996; 87: 1327-38.
47. Harada N, Tamai Y, Ishikawa T, et al. Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J 1999; 18: 5931-42.
48. Kellendonk C, Tronche F, Monaghan AP, et al. Regulation of Cre recombinase activity by the synthetic steroid RU 486. Nucleic Acids Res 1996; 24: 1404-11.
49. Feil R, Brocard J, Mascrez B, et al. Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci USA 1996; 93: 10887-90.
50. Baron U, Schnappinger D, Helbl V, et al. Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes. Proc Natl Acad Sci USA 1999; 96: 1013-8.
51. Utomo AR, Nikitin AY, Lee WH. Temporal, spatial, and cell type-specific control of Cre-mediated DNA recombination in transgenic mice. Nat Biotechnol 1999; 17: 1091-6.
52. Rickert RC, Roes J, Rajewsky K. B lymphocyte-specific, Cre-mediated mutagenesis in mice. Nucleic Acids Res 1997; 25: 1317-8.
53. Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998; 282: 1145-7.
54. Wolf E, Zakhartchenko V, Brem G. Nuclear transfer in mammals: recent developments and future perspectives. J Biotechnol 1998; 65: 99-110.
55. Sedivy JM, Dutriaux A. Gene targeting and somatic cell genetics: a rebirth or a coming of age? Trends Genet 1999; 15: 88-90.
56. Brustle O, Jones KN, Learish RD, et al. Embryonic stem cell-derived glial precursors : a source of myelinating transplants. Science 1999; 285: 754-6.
57. Keller GM. In vitro differentiation of embryonic stem cells. Curr Opin Cell Biol 1995; 7: 862-9.
58. Rossant J, Spence A, Rossant J. Chimeras and mosaics in mouse mutant analysis. Trends Genet 1998; 14: 358-63.
59. Araki K, Araki M, Yamamura K. Targeted integration of DNA using mutant lox sites in embryonic stem cells. Nucleic Acids Res 1997; 25: 868-72.
60. Donoho G, Jasin M, Berg P. Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells. Mol Cell Biol 1998; 18: 4070-8.
61. Cohen-Tannoudji M, Robine S, Choulika A, et al. I-Scel - induced gene replacement at a natural locus in embryonic stem cells. Mol Cell Biol 1998; 18: 1444-8.
62. Camus A, Barra J, Babinet C. À la recherche de gènes impliqués dans le développement embryonnaire de la souris: le «piégeage» de gènes. Med Sci 1998; 14: 1157-66.