Nuclear transfer in mammals: Recent developments and future perspectives

Journal of Biotechnology

Volumn 65, Issue 2-3, 1998, Pages 99-110

  Wolf, Eckhard ^a,b   Zakhartchenko, Valeri ^b   Brem, Gottfried ^b,c  

^a UNIVERSITY OF MUNICH   (Germany)

^b Bayerisches Forschungszentrum fur F   (Germany)

^c LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

Author keywords

Blastomere separation; Cloning; Embryo splitting; Gene farming; Nuclear transfer; Xenotransplantation

Indexed keywords

BIOLOGY; CELL CULTURE; CYTOLOGY; GENES; TRANSPLANTATION (SURGICAL);

BLASTOMERE SEPARATION; CYTOPLAST; EMBRYO SPLITTING; GENE FARMING; MAMMALS; NUCLEAR TRANSFER; XENOTRANSPLANTATION;

CLONING;

ANIMAL CELL; ANIMAL EXPERIMENT; BLASTOCYST; CELL CYCLE; CELL LINE; CELL NUCLEUS TRANSPLANTATION; CLONING; CONTROLLED STUDY; GENE TRANSFER; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; REVIEW; TECHNIQUE;

ANIMALS; CLONING, ORGANISM; EMBRYO TRANSFER; FEMALE; FORECASTING; MAMMALS; NUCLEAR TRANSFER TECHNIQUES; OOCYTES; PREGNANCY;

ANIMALIA; MAMMALIA;

EID: 0032573101     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1656(98)00132-1     Document Type: Review

References (109)

1. Adenot P.G., Szollosi M.S., Chesne P., Chastant S., Renard J.P. In vivo aging of oocytes influences the behavior of nuclei transferred to enucleated rabbit oocytes. Mol. Reprod. Dev. 46:1997;325-336.
2. Archibald A.L., Haley C.S., Brown J.F., Couperwhite S., McQueen H.A., Nicholson D., Coppieters W., Van de Weghe A., Stratil A., Wintero A.K.et al. The PiGMaP consortium linkage map of the pig (Sus scrofa). Mamm. Genome. 6:1995;157-175.
3. Ashworth et al., 1998. Nature 394, 329.
4. Barendse W., Vaiman D., Kemp S.J., Sugimoto Y., Armitage S.M., Williams J.L., Sun H.S., Eggen A., Agaba M., Aleyasin S.A., Band M., Bishop M.D., Buitkamp J., Byrne K., Collins F., Cooper L., Coppettiers W., Denys B., Drinkwater R.D., Easterday K., Elduque C., Ennis S., Erhardt G., Ferretti L., Zaragoza P.et al. A medium-density genetic linkage map of the bovine genome. Mamm. Genome. 8:1997;21-28.
5. Bishop M.D., Hawkins G.A., Keefer C.L. Use of DNA markers in animal selection. Theriogenology. 43:1995;61-70.
6. Bradley A., Liu P. Target practice in transgenics. Nat. Genet. 14:1996;121-123.
7. Brem, G., 1986. Mikromanipulation an Rinderembryonen. Enke, Stuttgart, 211 pp.
8. Bueler H., Aguzzi A., Sailer A., Greiner R.A., Autenried P., Aguet M., Weissmann C. Mice devoid of PrP are resistant to scrapie. Cell. 73:1993;1339-1347.
9. Butler D. French clone provides support for Dolly. Nature. 392:1998;113.
10. Campbell K., McWhir J., Ritchie M., Wilmut I. Production of live lambs following transfer of cultured embryonic disc cells. Theriogenology. 43:1995;181.
11. Campbell K.H., McWhir J., Ritchie W.A., Wilmut I. Sheep cloned by nuclear transfer from a cultured cell line. Nature. 380:1996;64-66.
12. Campbell K.H.S., Loi P., Otaegui P.J., Wilmut I. Cell cycle co-ordination in embryo cloning by nuclear transfer. Rev. Reprod. 1:1996;40-46.
13. Campbell K.H.S., Wilmut I. Totipotency or multipotentiality of cultured cells: applications and progress. Theriogenology. 47:1997;63-72.
14. Cheong H.T., Takahashi Y., Kanagawa H. Birth of mice after transplantation of early cell-cycle-stage embryonic nuclei into enucleated oocytes. Biol. Reprod. 48:1993;958-963.
15. Cheong H.T., Takahashi Y., Kanagawa H. Relationship between nuclear remodeling and subsequent development of mouse embryonic nuclei transferred to enucleated oocytes. Mol. Reprod. Dev. 37:1994;138-145.
16. Cherny R.A., Stokes T.M., Merei J., Lom L., Brandon M.R., Williams R.L. Strategies for the isolation and characterization of bovine embryonic stem cells. Reprod. Fertil. Dev. 6:1994;569-575.
17. Cibelli et al., 1998. Science 280, 1256-1258.
18. Clement-Sengewald A., Palma G.A., Berg U., Brem G. Comparison between in vitro produced and in vivo flushed donor embryos for cloning experiments in cattle. Theriogenology. 87:1992;196.
19. Collas P., Barnes F.L. Nuclear transplantation by microinjection of inner cell mass and granulosa cell nuclei. Mol. Reprod. Dev. 38:1994;264-267.
20. Collas P., Robl J.M. Factors affecting the efficiency of nuclear transplantation in the rabbit embryo. Biol. Reprod. 42:1990;877-884.
21. Collas P., Robl J.M. Development of rabbit nuclear transplant embryos from morula to blastocyst stage donor nuclei. Theriogenology. 35:1991;190.
22. Collas P., Balise J.J., Robl J.M. Influence of cell cycle stage of the donor nucleus on development of nuclear transplant rabbit embryos. Biol. Reprod. 46:1992;492-500.
23. Collas P., Pinto Correia C., Ponce de Leon F.A., Robl J.M. Effect of donor cell cycle stage on chromatin and spindle morphology in nuclear transplant rabbit embryos. Biol. Reprod. 46:1992;501-511.
24. Crawford A.M., Dodds K.G., Ede A.J., Pierson C.A., Montgomery G.W., Garmonsway H.G., Beattie A.E., Davies K., Maddox J.F., Kappes S.W.et al. An autosomal genetic linkage map of the sheep genome. Genetics. 140:1995;703-724.
25. Delhaise F., Ectors F.J., de Roover R., Ectors F., Dessy F. Nuclear transplantation using bovine primordial germ cells from male fetuses. Reprod. Fertil. Dev. 7:1995;1217-1219.
26. Dominko T., Mitalipova M., Haley B., Beyhan Z., Memili E., First N. Bovine oocyte as a universal recipient cytoplasm in mammalian nuclear transfer. Theriogenology. 49:1998;385.
27. Du F., Giles J.R., Foote R.H., Graves K.H., Yang X., Moreadith R.W. Nuclear transfer of putative rabbit embryonic stem cells leads to normal blastocyst development. J. Reprod. Fertil. 104:1995;219-223.
28. Fulka J. Jr., First N.L., Moor R.L. Nuclear transplantation in mammals: remodelling of transplanted nuclei under the influence of maturation promoting factor. BioEssays. 18:1996;835-840.
29. Galloway S.M., Hanrahan V., Dodds K.G., Potts M.D., Crawford A.M., Hill D.F. A linkage map of the ovine X chromosome. Genome Res. 6:1996;667-677.
30. Gardner D.K. Changes in requirements and utilization of nutrients during mammalian preimplantation embryo development and their significance in embryo culture. Theriogenology. 49:1998;83-102.
31. Garry F.B., Adams R., McCann J.P., Odde K.G. Postnatal characteristics of calves produced by nuclear transfer cloning. Theriogenology. 45:1996;141-152.
32. Gerfen R.W., Wheeler M.B. Isolation of embryonic cell lines from porcine blastocysts. Anim. Biotech. 61:1995;1-14.
33. Harrington J.J., Van Bokkelen G., Mays R.W., Gustashaw K., Willard H.F. Formation of de novo centromeres and construction of first-generation human artificial microchromosomes. Nat. Genet. 15:1997;345-355.
34. Heyman Y., Renard J.P. Cloning of domestic species. Anim. Reprod. Sci. 42:1996;427-436.
35. Keefer C.L., Stice S.L., Matthews D.L. Bovine inner cell mass cells as donor nuclei in the production of nuclear transfer embryos and calves. Biol. Reprod. 50:1994;935-939.
36. Kono T., Kwon O.Y., Ogawa M., Nakahara T. Development of mouse oocytes receiving embryonic nuclei and thymocytes. Theriogenology. 35:1991;227.
37. Kruip T.A.M., den Daas J.H.G. In vitro produced and cloned embryos: effects on pregnancy, parturition and offspring. Theriogenology. 47:1997;43-52.
38. Kwon O.Y., Kono T. Production of identical sextuplet mice by transferring metaphase nuclei from four-cell embryos. Proc. Natl. Acad. Sci. USA. 93:1996;13010-13013.
39. Lamberson W.R. Production of identical swine: uses for families with reduced phenotypic variations. Theriogenology. 41:1994;453-460.
40. Lavoir M.C., Basrur P.K., Betteridge K.J. Isolation and identification of germ cells from fetal bovine ovaries. Mol. Reprod. Dev. 37:1994;413-424.
41. Lavoir M.C., Rumph N., Moens A., King W.A., Plante Y., Johnson W.H., Ding J., Betteridge K.J. Development of bovine nuclear transfer embryos made with oogonia. Biol. Reprod. 56:1997;194-199.
42. Leichthammer F., Baunack E., Brem G. Behaviour of living primordial germ cells of livestock species in vitro. Theriogenology. 33:1990;1221-1230.
43. Lohuis M.M. Potential benefits of bovine embryo manipulation technologies to genetic improvement programs. Theriogenology. 43:1995;51-60.
44. Loi, L., Boyazoglu, S., Ledda, S., Gallus, M., Branca, A., Dattena, M., Naitana, S., Cappai, P., 1995. High efficiency of embryo cloning in sheep. In: Proc. Symposium on Reproduction and Animal Breeding, Milan, pp. 399-400.
45. Loi P., Ledda S., Cappai P. Nuclear dynamics and developmental potential of sheep nuclear transfer embryos treated with protein kinase inhibitor 6-dimethylaminopurine. Theriogenology. 47:1997;232.
46. Loskutoff N.M., Johnson W.H., Betteridge K.J. The developmental competence of bovine embryos with reduced cell numbers. Theriogenology. 39:1993;95-107.
47. Marklund L., Johansson Moller M., Hoyheim B., Davies W., Fredholm M., Juneja R.K., Mariani P., Coppieters W., Ellegren H., Andersson L. A comprehensive linkage map of the pig based on a wild pig-Large White intercross. Anim. Genet. 27:1996;255-269.
48. Matsui Y., Zsebo K., Hogan B.L. Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. Cell. 70:1992;841-847.
49. McGrath J., Solter D. Nuclear transplantation in the mouse embryo by microsurgery and cell fusion. Science. 220:1983;1300-1302.
50. McWhir J., Schnieke A.E., Ansell R., Wallace H., Colman A., Scott A.R., Kind A.J. Selective ablation of differentiated cells permits isolation of embryonic stem cell lines from murine embryos with a non-permissive genetic background. Nat. Genet. 14:1996;223-226.
51. Meng L., Ely J.J., Stouffer R.L., Wolf D.P. Rhesus monkeys produced by nuclear transfer. Biol. Reprod. 57:1997;454-459.
52. Modlinski J.A., Smorag Z. Preimplantation development of rabbit embryos after transfer of embryonic nuclei into different cytoplasmic environment. Mol. Reprod. Dev. 28:1991;361-372.
53. Moens A., Chesne P., Delhaise F., Delval A., Ectors F.J., Dessy F., Renard J.P., Heyman Y. Assessment of nuclear totipotency of fetal bovine diploid germ cells by nuclear transfer. Theriogenology. 46:1996;871-880.
54. Moreadith R.W., Radford N.B. Gene targeting in embryonic stem cells: the new physiology and metabolism. J. Mol. Med. 75:1997;208-216.
55. Nagashima H., Ashman R.J., Nottle M.B. Nuclear transfer of porcine embryos using cryopreserved delipated blastomeres as donor nuclei. Mol. Reprod. Dev. 48:1997;339-343.
56. Notarianni E., Galli C., Laurie S., Moor R.M., Evans M.J. Derivation of pluripotent, embryonic cell lines from the pig and sheep. J. Reprod. Fertil. Suppl. 43:1991;255-260.
57. Notarianni E., Laurie S., NG A., Sathasivam K. Incorporation of cultured embryonic cells into transgenic and chimeric, porcine fetuses. Int. J. Dev. Biol. 41:1997;537-540.
58. Otaegui P.J., O'Neill G.T., Campbell K.H., Wilmut I. Transfer of nuclei from 8-cell stage mouse embryos following use of nocodazole to control the cell cycle. Mol. Reprod. Dev. 39:1994;147-152.
59. Pinto Correia C., Long C.R., Chang T., Robl J.M. Factors involved in nuclear reprogramming during early development in the rabbit. Mol. Reprod. Dev. 40:1995;292-304.
60. Prather R.S., Day B.N. Practical considerations for the in vitro production of pig embryos. Theriogenology. 49:1998;23-32.
61. Prather R.S., Barnes F.L., Sims M.M., Robl J.M., Eyestone W.H., First N.L. Nuclear transplantation in the bovine embryo: assessment of donor nuclei and recipient oocyte. Biol. Reprod. 37:1987;859-866.
62. Prather R.S., Sims M.M., First N.L. Nuclear transplantation in early pig embryos. Biol. Reprod. 41:1989;414-418.
63. Resnick J.L., Bixler L.S., Cheng L., Donovan P.J. Long-term proliferation of mouse primordial germ cells in culture. Nature. 359:1992;550-551.
64. Schnieke A.E., Kind A.J., Ritchie W.A., Mycock K., Scott A.R., Ritchie M., Wilmut I., Colman A., Campbell K.H.S. Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts. Science. 278:1997;2130-2133.
65. Shim H., Gutierrez-Adan A., Chen L.-R., BonDurant R.H., Behboodi E., Anderson G.B. Isolation of pluripotent stem cells from cultured porcine primordial germ cells. Biol. Reprod. 57:1997;1089-1095.
66. Sgaramella V., Zinder N.D. Dolly confirmation. Science. 279:1998;635-636.
67. Signer et al., 1998. Nature 394, 329-330.
68. Sims M., First N.L. Production of calves by transfer of nuclei from cultured inner cell mass cells. Proc. Natl. Acad. Sci. USA. 91:1994;6143-6147.
69. Smith C. Cloning and genetic improvement of beef cattle. Anim. Prod. 49:1989;163-169.
70. Smith L.C., Wilmut I. Influence of nuclear and cytoplasmic activity on the development in vivo of sheep embryos after nuclear transplantation. Biol. Reprod. 40:1989;1027-1035.
71. Smith L.C., Wilmut I., Hunter R.H. Influence of cell cycle stage at nuclear transplantation on the development in vitro of mouse embryos. J. Reprod. Fertil. 84:1988;619-624.
72. Solter D., Aronson J., Gilbert S.F., McGrath J. Nuclear transfer in mouse embryos: activation of the embryonic genome. Cold Spring Harbor Symp. Quant. Biol. 50:1985;45-50.
73. Stein-Stefani J., Holtz W. Splitting of porcine embryos at the four-cell or morula stage. Theriogenology. 41:1994;961-968.
74. Stice S.L., Keefer C.L. Multiple generational bovine embryo cloning. Biol. Reprod. 48:1993;715-719.
75. Stice S.L., Robl J.M. Nuclear reprogramming in nuclear transplant rabbit embryos. Biol. Reprod. 39:1988;657-664.
76. Stice S.L., Keefer C.L., Matthews L. Bovine nuclear transfer embryos: oocyte activation prior to blastomere fusion. Mol. Reprod. Dev. 38:1994;61-68.
77. Stice S.L., Strelchenko N.S., Keefer C.L., Matthews L. Pluripotent bovine embryonic cell lines direct embryonic development following nuclear transfer. Biol. Reprod. 54:1996;100-110.
78. Stice S.L., Robl J.M., Ponce de Leon F.A., Jerry J., Golueke P.G., Cibelli J.B., Kane J.J. Cloning: new breakthroughs leading to commercial opportunities. Theriogenology. 49:1998;129-138.
79. Strelchenko N. Bovine pluripotent stem cells. Theriogenology. 45:1996;131-140.
80. Tearle R.G., Tange M.J., Zannettino Z.L., Katerelos M., Shinkel T.A., Van Denderen B.J., Lonie A.J., Lyons I., Nottle M.B., Cox T., Becker C., Peura A.M., Wigley P.L., Crawford R.J., Robins A.J., Pearse M.J., d'Apice A.J. The alpha-1,3-galactosyltransferase knockout mouse. Implications for xenotransplantation. Transplantation. 61:1996;13-19.
81. Thomson J.A., Kalishman J., Golos T.G., Durning M., Harris C.P., Becker R.A., Hearn J.P. Isolation of a primate embryonic stem cell line. Proc. Natl. Acad. Sci. USA. 92:1995;7844-7848.
82. Thomson J.A., Kalishman J., Golos T.G., Durning M., Harris C.P., Hearn J.P. Pluripotent cell lines derived from common marmoset (Callithrix jacchus) blastocysts. Biol. Reprod. 55:1996;254-259.
83. Tomizuka K., Yoshida H., Uejima H., Kugoh H., Sato K., Ohguma A., Hayasaka M., Hanaoka K., Oshimura M., Ishida I. Functional expression and germline transmission of a human chromosome fragment in chimaeric mice. Nat. Genet. 16:1997;133-143.
84. Tsunoda Y., Kato Y. Full-term development after transfer of nuclei from 4-cell and compacted morula stage embryos to enucleated oocytes in the mouse. J. Exp. Zool. 278:1997;250-254.
85. Vaiman D., Schibler L., Bourgeois F., Oustry A., Amigues Y., Cribiu E.P. A genetic linkage map of the male goat genome. Genetics. 144:1996;279-305.
86. Van Stekelenburg Hamers A.E., van Inzen W.G., Van Achterberg T.A., Kruip T.A., de Laat S.W., Weima S.M. Nuclear transfer and electrofusion in bovine in vitro-matured/in vitro-fertilized embryos: effect of media and electrical fusion parameters. Mol. Reprod. Dev. 36:1993;307-312.
87. Vignon X., Chesne P., LeBourhis D., Heyman Y., Renard J.P. Developmental potential of bovine embryos reconstructed with somatic nuclei from cultured skin and muscle fetal cells. Theriogenology. 49:1998;392.
88. Wakayama et al., 1998. Nature 394, 369-374.
89. Walker S.K., Hartwich K.M., Seamark R.F. The production of unusually large offspring following embryo manipulation: concepts and challenges. Theriogenology. 45:1996;111-120.
90. Wall R.J. Transgenic livestock: progress and prospects for the future. Theriogenology. 45:1996;57-68.
91. Wells D.N., Misica P.M., Day T.A., Tervit H.R. Production of cloned lambs from an established embryonic cell line: a comparison between in vivo- and in vitro-matured cytoplasts. Biol. Reprod. 57:1997;385-393.
92. Wells D.N., Misica P.M., McMillan W.H., Tervit H.R. Production of cloned bovine fetuses following nuclear transfer using cells from a fetal fibroblast cell line. Theriogenology. 49:1998;330.
93. Westhusin M.E., Pryor J.H., Bondioli K.R. Nuclear transfer in the bovine embryo: a comparison of 5-day, 6-day, frozen-thawed, and nuclear transfer donor embryos. Mol. Reprod. Dev. 28:1991;119-123.
94. Willadsen S.M. A method for culture of micromanipulated sheep embryos and its use to produce monozygotic twins. Nature. 277:1979;298-300.
95. Willadsen S.M. The development capacity of blastomeres from 4- and 8-cell sheep embryos. J. Embryol. Exp. Morphol. 65:1981;165-172.
96. Willadsen S.M. Nuclear transplantation in sheep embryos. Nature. 320:1986;63-65.
97. Willadsen S.M., Polge C. Attempts to produce monozygotic quadruplets in cattle by blastomere separation. Vet. Rec. 108:1981;211-213.
98. Wilmut I., Schnieke A.E., McWhir J., Kind A.J., Campbell K.H. Viable offspring derived from fetal and adult mammalian cells. Nature. 385:1997;810-813.
99. Wilson J.M., Williams J.D., Bondioli K.R., Looney C.R., Westhusin M.E., McCalla D.F. Comparison of birth weight and growth characteristics of bovine calves produced by nuclear transfer (cloning), embryo transfer and natural mating. Anim. Reprod. Sci. 38:1995;73-83.
100. Wolf, E., Stojkovic, M., Wenigerkind, H., Santl, B., Prelle, K., Reichenbach, H.D., Zakhartchenko, V., Schernthaner, W., Palma, G.A., Brem, G. 1997. Some factors affecting the efficiency of in vitro production of bovine embryos and related techniques. In: Li, N., Chen, Y. (Eds.), Proc. International Conference on Animal Biotechnology. Beijing: International Academic Publishers, pp. 285-291.
101. Yang X., Jiang S., Kovacs A., Foote R.H. Nuclear totipotency of cultured rabbit morulae to support full-term development following nuclear transfer. Biol. Reprod. 47:1992;636-643.
102. Yang X., Jiang S., Farrell P., Foote R.H., McGrath A.B. Nuclear transfer in cattle: effect of nuclear donor cells, cytoplast age, co-culture, and embryo transfer. Mol. Reprod. Dev. 35:1993;29-36.
103. Yong Z., Yuqiang L. Nuclear-cytoplasmic interaction and development of goat embryos reconstructed by nuclear transplantation: production of goats by serially cloning embryos. Biol. Reprod. 58:1998;266-269.
104. Yong Z., Jianchen W., Jufen Q., Zhiming H. Nuclear transplantation in goats. Theriogenology. 35:1991;299.
105. Zakhartchenko V., Wolf E., Palma G.A., Brem G. Effect of donor embryo cell number and cell size on the efficiency of bovine embryo cloning. Mol. Reprod. Dev. 42:1995;53-57.
106. Zakhartchenko V., Reichenbach H.D., Riedl J., Palma G.A., Wolf E., Brem G. Nuclear transfer in cattle using in vivo-derived vs. in vitro-produced donor embryos: effect of developmental stage. Mol. Reprod. Dev. 44:1996;493-498.
107. Zakhartchenko V., Stojkovic M., Brem G., Wolf E. Karyoplast-cytoplast volume ratio in bovine nuclear transfer embryos: effect on developmental potential. Mol. Reprod. Dev. 48:1997;332-338.
108. Zakhartchenko V., Reichenbach H.-D., Stojkovic M., Boxhammer K., Brem G., Wolf E. Hatching of bovine nuclear transfer embryos: effect on pregnancy rate. Reprod. Dom. Anim. Suppl. 5:1998;14.
109. Zakhartchenko V., Schernthaner W., Stojkovic M., Düchler M., Bugingo C., Wolf E., Brem G. Cultured bovine mammary gland cells as donors for nuclear transfer. Theriogenology. 49:1998;332.