Covalent modification of subtilisin Bacillus lentus Cysteine mutants with enantiomerically pure chiral auxiliaries causes remarkable changes in activity

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 8, 2000, Pages 1957-1968

  Dickman, Michael ^a   Jones, J Bryan ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDASE; CYSTEINE; ESTERASE; SUBTILISIN;

ARTICLE; BACTERIUM MUTANT; CHIRALITY; CHROMATOGRAPHY; CONTROLLED STUDY; EGGERTHELLA LENTA; ENANTIOMER; ENZYME KINETICS; NONHUMAN; STRUCTURE ACTIVITY RELATION;

AMIDOHYDROLASES; BACILLUS; CYSTEINE; ESTERASES; KINETICS; LIGANDS; MANDELIC ACIDS; MOLECULAR STRUCTURE; MUTATION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEREOISOMERISM; SUBSTRATE SPECIFICITY; SUBTILISIN;

BACILLUS LENTUS; FELIS CATUS;

EID: 0033868509     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00121-8     Document Type: Article

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