Site-directed mutagenesis combined with chemical modification as a strategy for altering the specificity of the S1 and S1' pockets of subtilisin Bacillus lentus

Biochemistry

Volumn 37, Issue 17, 1998, Pages 5968-5973

  DeSantis, Grace ^a   Berglund, Per ^a,b   Stabile, Michele R ^a,c   Gold, Marvin ^d   Jones, J Bryan ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^c ARQULE INC   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

SUBTILISIN;

AMINO ACID SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; EGGERTHELLA LENTA; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME SPECIFICITY; ENZYME STABILITY; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

BACILLUS LENTUS; BACTERIA (MICROORGANISMS); EGGERTHELLA LENTA; FELIS CATUS;

EID: 0032574793     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9727951     Document Type: Article

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