Oxygenation predicts radiation response and survival in patients with cervix cancer

Radiotherapy and Oncology

Volumn 48, Issue 2, 1998, Pages 149-156

  Fyles, Anthony W ^a,b   Milosevic, Michael ^a,b   Wong, Raimond ^a,b   Kavanagh, Mary Claire ^a   Pintilie, Melania ^a   Sun, Alex ^a   Chapman, William ^a   Levin, Wilf ^a,b   Manchul, Lee ^a,b   Keane, Thomas J ^a,b   Hill, Richard P ^a,b  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cervix carcinoma; Hypoxia; Oxygen electrode; Predictive assay; Radiation therapy

Indexed keywords

FENTANYL; HEMOGLOBIN; PROPOFOL;

ADULT; AGED; ARTICLE; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER RECURRENCE; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; HYPOXEMIA; MAJOR CLINICAL STUDY; OXYGEN ELECTRODE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RADIATION DOSE; SURVIVAL TIME; TISSUE OXYGENATION; TREATMENT OUTCOME; TUMOR VOLUME; UTERINE CERVIX CANCER;

ADENOCARCINOMA; ADULT; AGED; ANALYSIS OF VARIANCE; BRACHYTHERAPY; CARCINOMA, ADENOSQUAMOUS; CARCINOMA, SQUAMOUS CELL; CELL HYPOXIA; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; FORECASTING; HUMANS; ION-SELECTIVE ELECTRODES; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; OXYGEN; OXYGEN CONSUMPTION; POLAROGRAPHY; PROGNOSIS; PROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME; UTERINE CERVICAL NEOPLASMS;

EID: 0031716020     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-8140(98)00044-9     Document Type: Article

References (32)

1. Badib, A.O. and Webster, J.H. Changes in tumor oxygen tension during radiation therapy. Acta Radiol. Ther. Phys. Biol. 8: 247-257, 1969.
2. Bates, M.L., Feingold, A. and Gold, M. The effects of anesthetics on an in-vivo oxygen electrode. Am. J. Clin. Pathol. 64: 448-451, 1975.
3. Brizel, D.M., Rosner, G.L., Harrelson, J., Prosnitz, L.R. and Dewhirst, M.W. Pretreatment oxygenation profiles of human soft tissue sarcomas. Int. J. Radiat. Oncol. Biol. Phys. 30: 635-642, 1994.
4. Brizel, D.M., Rosner, G.L., Prosnitz, L.R. and Dewhirst, M.W. Patterns and variability of tumor oxygenation in human soft tissue sarcomas, cervical carcinomas, and lymph node metastases. Int. J. Radiat. Oncol. Biol. Phys. 32: 1121-1125, 1995.
5. Brizel, D.M., Scully, S.P., Harrelson, J.M., et al. Tumor oxygenation predicts for likelihood of distant metastases in human soft tissue sarcoma. Cancer Res. 56: 941-943, 1996.
6. Brizel, D.M., Sibley, G.S., Prosnitz, L.R., Scher, R.L. and Dewhirst, M.W. Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck. Int. J. Radiat. Oncol. Biol. Phys. 38: 285-289, 1997.
7. Bush, R.S., Jenkin, R.D.T., Allt, W.E.C., et al. Definitive evidence for hypoxic cells influencing cure in cancer therapy. Br. J. Cancer 37 (Suppl. III): 302-306, 1978.
8. Cater, D.B. and Silver, I.A. Quantitative measurements of oxygen tension in normal tissues and in the tumours of patients before and after radiotherapy. Acta Radiol. 53: 233-255, 1959.
9. Claffey, K.P., Brown, L.F., del Aguila, L.F., et al. Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Res. 56: 172-181, 1996.
10. Dent, J.G. and Netter, K.J. Errors in oxygen tension measurements caused by halothane. Br. J. Anaesth. 48: 195-197, 1976.
11. 2 histography. Br. J. Cancer 66: 919-924, 1992.
12. Gatenby, R.A., Kessler, H.B., Rosenblum, J.S., et al. Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy. Int. J. Radiat. Oncol. Biol. Phys. 14: 831-838, 1988.
13. Girinsky, T., Pejovic-Lenfant, M.H., Bourhis, J., et al. Prognostic value of hemoglobin concentrations and blood transfusions in advanced carcinoma of the cervix treated by radiation therapy: results of a retrospective study of 386 patients. Int. J. Radiat. Oncol. Biol. Phys. 16: 37-42, 1989.
14. Graeber, T.G., Osmanian, C., Jacks, T., et al. Hypoxia mediated selection of cells with diminished apoptotic potential in solid tumors. Nature 379: 88-91, 1996.
15. 2 predicts survival in advanced cancer of the uterine cervix. Radiother. Oncol. 26: 45-50, 1993.
16. 2 tension measurements. Cancer Res. 51: 6098-6102, 1991.
17. Höckel, M., Schlenger, K., Aral, B., Mitze, M., Schäffer, U., and Vaupel, P. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res. 56: 4509-4515, 1996.
18. Kapp, D.S., Fischer, D., Gutierrez, E., Kohorn, E.I. and Schwartz, P.E. Pretreatment prognostic factors in carcinoma of the uterine cervix: a multivariable analysis of the effect of age, stage, histology and blood counts on survival. Int. J. Radiat. Oncol. Biol. Phys. 9: 445-455, 1983.
19. 3H-misonidazole binding and paired survival analysis. Radiat Res. 145: 491-500, 1996.
20. Kolstad, P. Intercapillary distance, oxygen tension and local recurrence in cervix cancer. Scand. J. Clin. Lab. Invest. 106: 145-157, 1968.
21. Lartigau, E., Randrianarivelo, H., Martin, L., et al. Oxygen tension measurements in human tumours: the Institut Gustave-Roussy experience. Radiat. Oncol. Invest. 1: 285-291, 1994.
22. McHugh, R.D., Epstein, R.M. and Longnecker, D.E. Halothane mimics oxygen in oxygen microelectrodes. Anesthesiology 50: 47-49, 1979.
23. Nordsmark, M., Bentzen, S.M. and Overgaard, J. Measurement of human tumour oxygenation status by a polarographic needle electrode. Acta Oncol. 33: 383-389, 1994.
24. Nordsmark, M., Overgaard, M. and Overgaard, J. Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother. Oncol. 41: 31-39, 1996.
25. Overgaard, J. Clinical evaluation of nitroimidazoles as modifiers of hypoxia in solid tumors. Oncol. Res. 6: 509-518, 1994.
26. Pappova, N., Siracka, E., Vacek, A. and Durkovsky, J. Oxygen tension and prediction of the radiation response. Polarographic study in human breast cancer. Neoplasma 29: 669-674, 1982.
27. Shweiki, D., Neeman, M., Itin, A. and Keshet, E. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis. Proc. Natl. Acad. Sci. USA 92: 768-772, 1995.
28. Stone, H.B., Minchinton, A.I., Lemmon, M., Menke, D. and Brown, J.M. Pharmacological modification of tumour blood flow: lack of correlation between alterations of mean arterial blood pressure and changes in tumor perfusion. Int. J. Radiat. Oncol. Biol. Phys. 22: 79-86, 1992.
29. 2 in cervix carcinoma. Gynecol. Oncol. 64: 230-236, 1997.
30. Terris, D.J. and Dunphy, E.P. Oxygen tension measurements of head and neck cancers. Arch. Otolaryngol. Head Neck Surg. 120: 283-287, 1994.
31. 2 tension measurements. Cancer Res. 51: 3316-3322, 1991.
32. Wong, R., Fyles, A., Milosevic, M., Pintilie, M. and Hill, R. Heterogeneity of polarographic oxygen electrode measurements in cervix cancer: an evaluation of intra- and inter-tumour variability, probe position and track depth. Int. J. Radiat. Oncol. Biol. Phys. 39: 405-412, 1997.