The role of calcineurin in lymphocyte activation

Seminars in Immunology

Volumn 12, Issue 4, 2000, Pages 405-415

  Baksh, Shairaz ^a   Burakoff, Steven J ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Calcineurin; Immunophilins; NFAT; T lymphocyte

Indexed keywords

CALCINEURIN;

ARTICLE; CELL SURFACE; HUMAN; IMMUNOREGULATION; LYMPHOCYTE ACTIVATION; NONHUMAN; SECOND MESSENGER; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 0033804760     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1006/smim.2000.0221     Document Type: Article

References (72)

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28. Differential activation of transcription factors induced by Ca2+ response amplitude and duration
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32. Superoxide dismutase protects calcineurin from inactivation
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34. L-type calcium channels and GSK-3 regulate the activity of NFATc4 in hippocampal neurons
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50. IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATcl
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55. AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region
56. Dissection of protein kinase and phosphatase targeting interactions
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58. Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux
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60. Involvement of the brain type of ryanodine receptor in T-cell proliferation
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64. Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A
65. B cell apoptosis triggered by antigen receptor ligation proceeds via a nove caspase-dependent pathway
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