FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine- proline (1400-1401) and anchors calcineurin to this FK506-like domain

Journal of Biological Chemistry

Volumn 272, Issue 44, 1997, Pages 27582-27588

  Cameron, Andrew M ^a   Nucifora Jr , Frederick C ^a   Fung, Eric T ^a   Livingston, David J ^b   Aldape, Robert A ^b   Ross, Christopher A ^a   Snyder, Solomon H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; LEUCINE; PROLINE; RYANODINE RECEPTOR; TACROLIMUS;

ARTICLE; CALCIUM TRANSPORT; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE DISRUPTION; GENETIC CONSERVATION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE ACTIVATION;

AMINO ACID SEQUENCE; CALCINEURIN; CALCIUM CHANNELS; CARRIER PROTEINS; DNA-BINDING PROTEINS; HEAT-SHOCK PROTEINS; LEUCINE; MOLECULAR SEQUENCE DATA; PROLINE; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; TACROLIMUS; TACROLIMUS BINDING PROTEINS;

EID: 0030784252     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.44.27582     Document Type: Article

References (29)

1. Schreiber, S. L. (1991) Science 251, 283-287
2. Snyder, S. H., and Sabatini, D. M. (1995) Nat. Med. 1, 32-37
3. Bierer, B. E., Somers, P. K., Wandless, T. J., Burakoff, S. J., and Schreiber, S. L. (1990) Science 250, 556-559
4. Liu, J.., Farmer, J. D., Lane, W. S., Friedman, J., Weissman, I., and Schreiber, S. L. (1991) Cell 66, 807-815
5. O'Keefe, S. J., Tamura, J., Kincaid, R. L., Tocci, M. J., and O'Neill, E. A. (1992) Nature 357, 692-694
6. Clipstone, N. A., and Crabtree, G. R. (1992) Nature 357, 695-697
7. Steinmann, B., Bruckner, P., and Supertifurga, A. (1991) J. Biol. Chem. 266, 1299-1303
8. Lodish, H. F., and Kong, N. (1991) J. Biol. Chem. 266, 14835-14838
9. Jayaraman, T., Brillantes, A., Timerman, A. P., Fleischer, S., Erdjument-Bromage, H., Tempst, P., and Marks, A. R., (1992) J. Biol. Chem. 267, 9474-9477
10. Cameron, A. M., Steiner, J. P., Sabatini, D. M., Kaplin, A. I., Walensky, L. D., and Snyder, S. H. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 1784-1788
11. Timerman, A. P., Ogunbumni, E., Freund, E., Wiederrecht, G., Marks, A. R., and Fleischer, S. (1993) J. Biol. Chem. 268, 22992-22999
12. Brillantes, A. B., Ondrias, K., Scott, A., Kobrinsky, E., Ondrisova, E., Moschella, M. C., Jayaraman, T., Landers, M., Ehrlich, B. E., and Marks, A. R. (1994) Cell 77, 513-523
13. Cameron, A. M., Steiner, J. P., Roskams, A. J., Ali, S. M., Ronnett, G. V., and Snyder, S. H. (1995) Cell 83, 463-472
14. Timerman A. P., Wiederrecht, G., Marcy, A., and Fleischer, S. (1995) J. Biol. Chem. 270, 2451-2459
15. Aldape, R. A., Futer, O., DeCenzo, M. T., Jarrett, B. P., Murcko, M. A., and Livingston, D. J. (1992) J. Biol. Chem. 267, 16029-16032
16. Futer, O., DeCenzo, M. T., Aldape, R. A., and Livingston, D. J. (1995) J. Biol. Chem. 270, 18935-18940
17. Chevray, P. M., and Nathans, D. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 5789-5793
18. Marcus S., Polverino, A., Barr, M., and Wigler, M. (1994) Proc.. Natl. Acad. Sci. U. S. A. 91, 7762-7766
19. Furuichi, T., and Mikoshiba, K. (1995) J. Neurochem. 64, 953-960
20. Ikeda, Y., Schultz, W., Clardy, J., and Schreiber, S. L. (1994) J. Am. Chem. Soc. 116, 4143-4144
21. Albers, M. W., Walsh, C. T., and Schreiber, S. L. (1990) J. Org. Chem. 55, 4984-4986
22. Wang, T., Donahoe, P. K., and Zervos, A. S. (1994) Science 265, 674-676
23. Derynck, R. (1994) Trends Biochem. Sci. 19, 548-633
24. Wang, T., Li, B.-Y., Danielson, P. D., Shah, P. C., Rockwell, S., Lechleider, R. J., Martin, J., Manganaro, T., and Donahoe, P. K. (1996) Cell 86, 435-444
25. Klauck, T. M., Faux, M. C., Labudda, K., Langeberg, L. K., Jaken, S., and Scott, J. D. (1996) Science 271, 1589-1592
26. Griffith J P. Kim, J. L., Kim, E. E., Sintchak, M. D., Thomson, J. A., Fitzgibbon, M. J., Fleming, M. A, Caron, P. R., Hsiao, K., and Navia, M. A. (1995) Cell 82, 507-522
27. Kissinger, C. R., Parge, H. E., Knighton, D. R., Lewis, C. T., Pelletier, L. A., Tempczyk, A., Kalish, V. J., Tucker, K. D., Showalter, R. E., Moomaw, E. W., Gastinel, L. N., Habuka, N., Chen, X., Maldonado, F., Barker, J. E., Bacquet, R., and Villafranca, E. (1995) Nature 378, 641-644
28. Clipstone, N. A., Fiorentino, D. F., and Crabtree, G. R. (1994) J. Biol. Chem. 269, 26431-26437
29. Coghlan, V. M., Perrino, B. A., Howard, M., Langeberg, L. K., Kicks, J. B., Gallatin, W. M., and Scott, J. D. (1995) Science 267, 108-111