A genomic island, termed high-pathogenicity island, is present in certain non-O157 Shiga toxin-producing Escherichia coli clonal lineages

Infection and Immunity

Volumn 67, Issue 11, 1999, Pages 5994-6001

  Karch, H ^a,d   Schubert, S ^b   Zhang, D ^c   Zhang, W ^a   Schmidt, H ^a   Olschlager T ^c   Hacker, J ^c  

^a Inst fur Hygiene und Mikrobiologie   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c Inst fur Molek Infektionsbiologie   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE; POLYPEPTIDE; SHIGA TOXIN; SIDEROPHORE; VIRULENCE FACTOR;

ARTICLE; BACTERIAL GENETICS; CONTROLLED STUDY; ESCHERICHIA COLI; GENE LOCUS; GENETIC ANALYSIS; IMMUNOBLOTTING; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PRIORITY JOURNAL; STRAIN DIFFERENCE; YERSINIA;

ESCHERICHIA COLI; YERSINIA;

EID: 0032729647     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.11.5994-6001.1999     Document Type: Article

References (54)

1. Blattner, F. R., G. Plunkett III, C. A. Bloch, N. T. Perna, V. Burland, M. Riley, J. Collado-Vides, J. D. Glasner, C. K. Rode, G. F. Mayhew, J. Gregor, N. W. Davis, H. A. Kirkpatrick, M. A. Goeden, D. J. Rose, B. Mau, and Y. Shao. 1997. The complete genome sequence of E. coli K-12. Science 277: 1453-1474.
2. Blum, G., M. Ott, A. Lischewski, A. Ritter, H. Imrich, H. Tschäpe, and J. Hacker. 1994. Excision of large DNA regions termed pathogenicity islands from tRNA-speciflc loci in the chromosome of an Escherichia coli wild-type pathogen. Infect. Immun. 2:605-614.
3. Blum-Oehler, G., U. Dobrindt, N. Weiß, B. Janke, S. Schubert, A. Rakin, J. Heesemann, R. Marre, and J. Hacker. 1998. Pathogenicity islands of uropathogenic Escherichia coli: implications for the evolution of virulence. Zentbl. Bakteriol. Suppl. 29:380-386.
4. Bockemühl, J., S. Aleksic, and H. Karch. 1992. Serological and biochemical properties of Shiga-like toxin (verocytotoxin)-producing strains of Escherichia coli, other than O-group 157, from patients in Germany. Zentbl. Bakteriol. 276:189-195.
5. Bockemühl, J., H. Karch, and H. Tschäpe. 1998. Zur situation der infektionen des menschen durch enterohämorrhagische Escherichia coli (EHEC) in Deutschland 1997. Bundesgesundheitsblatt 41:2-5.
6. Bokete, T. N., T. S. Whittam, R. A. Wilson, C. R. Clausen, C. M. O'Callahan, S. L. Moseley, T. R. Fritsche, and P. I. Tarr. 1997. Genetic and phenotypic analysis of Escherichia coli with enteropathogenic characteristics isolated from Seattle children. J. Infect. Dis. 175:1382-1389.
7. Buchrieser, C., R. Brosch, S. Bach, A. Guiyoule, and E. Carniel. 1998. The high pathogenicity island of Yersinia pseudotuberculosis can be inserted into any of the three chromosomal asn tRNA genes. Mol. Microbiol. 30:965-978.
8. Caprioli, A., A. E. Tozzi, G. Rizzoni, and H. Karch. 1997. Non-O157 Shiga toxin-producing Escherichia coli infections in Europe. Emerg. Infect. Dis. 3:578-579.
9. Carniel, E., I. Guilvout, and M. Prentice. 1996. Characterization of a large chromosomal "high pathogenicity island" in biotype IB Yersinia enterocolitica. J. Bacteriol. 178:6743-6751.
10. Cebula, T. A., W. L. Payne, and P. Feng. 1995. Simultaneous identification of strains of Escherichia coli serotype O157:H7 and their Shiga-like toxin type by mismatch amplification mutation assay-multiplex PCR. J. Clin. Microbiol. 33:248-250.
11. Elliott, S. J., L. A. Wainwright, T. K. McDaniel, K. G. Jarvis, Y. K. Deng, L. C. Lai, B. P. McNamara, M. S. Donnenberg, and J. K. Kaper. 1998. The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69. Mol. Microbiol. 28:1-4.
12. Finlay, B. B., and S. Falkow. 1997. Common themes in microbial pathogenicity revised. Microbiol. Mol. Biol. Rev. 61:136-169.
13. Gehring, A. M., E. DeMoll, J. D. Felherston, I. Mori, G. F. Meyhew, F. R. Blattner, T. C. Walsh, and R. D. Perry. 1998. Iron acquisition in plaque: modular logic in enzymatic biogenesis of yersiniabactin by Yersinia pestis. Chem. Biol. 5:573-586.
14. Gunzer, F., H. Böhm, H. Rüssmann, M. Bitzan, S. Aleksic, and H. Karch. 1992. Molecular detection of sorbitol-fermenting Escherichia coli O157 in patients with hemolytic-uremic syndrome. J. Clin. Microbiol. 30:1807-1810.
15. Hacker, J., G. Blum-Oehler, I. Mühldorfer, and H. Tschäpe. 1997. Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution. Mol. Microbiol. 23:1089-1097.
16. Hacker, J., G. Blum-Oehler, B. Janke, G. Nagy, and W. Goebel. 1999. Pathogenicity islands of extraintestinal Escherichia coli, p. 59-76. In J. Kaper and J. Hacker (ed.), Pathogenicity islands and other mobile virulence elements. ASM Press, Washington, D.C.
17. Hacker, J., and J. Kaper. 1999. The concept of pathogenicity islands, p. 1-11. In J. Kaper and J. Hacker (ed.), Pathogenicity islands and other mobile virulence elements. ASM Press, Washington, D.C.
18. Hames, B. D. 1987. Introduction to polyacrylamide gel electrophoresis, p. 1-91. In B. D. Hames and D. Rickwood (ed.), Gel electrophoresis of proteins: a practical approach. IRL Press, Washington, D1C.
19. Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
20. Heesemann, J. 1987. Chromosomal-encoded siderophores are required for mouse virulence of enteropathogenic Yersinia species. FEMS Microbiol. Lett. 48:229-233.
21. Heesemann, J., K. Hantke, T. Vocke, E. Saken, A. Rakin, I. Stojiljkovic, and R. Berner. 1993. Virulence of Yersinia enterocolitica is closely associated with siderophore production, expression of an iron-repressible outer membrane protein of 65000 Da and pesticin sensitivity. Mol. Microbiol. 8:397-408.
22. Kaper, J. B., S. Elliott, V. Sperandio, N. T. Perna, G. F. Mayhew, and F. R. Blattner. 1998. Attaching-and-effacing intestinal histopathology and the locus of enterocyte effacement, p. 163-182. In J. B. Kaper and A. D. O'Brien (ed.), Escherichia coli O157.-H7 and other Shiga toxin-producing E. coli strains. American Society for Microbiology, Washington, D.C.
23. Karch, H., H.-I. Huppertz, J. Bockemühl, H. Schmidt, A. Schwarzkopf, and R. Lissner. 1997. Shiga toxin-producing Escherichia coli infections in Germany. J. Food. Prot. 11:1454-1457.
24. Karch, H., H. Schmidt, and W. Brunder. 1998. Plasmid-encoded determinants of Escherichia coli O157:H7, p. 183-194. In J. B. Kaper and A. D. O'Brien (ed.), Escherichia coli O157:H7 and other Shiga toxin-producing E. coli strains. American Society for Microbiology, Washington, D.C.
25. Karmali, M. A., M. Petric, S. Louie, and R. Cheung. 1986. Antigenic heterogeneity of Escherichia coli verotoxins. Lancet 1:164-165.
26. Lawrence, J. G., and H. Ochman. 1998. Molecular archaeology of the Escherichia coli genome. Proc. Natl. Acad. Sci. USA 95:9413-9417.
27. Mariani Kurkdjian, P., E. Denamur, A. Milan, B. Picard, H. Cave, N. Lambert Zechovsky, C. Loirat, P. Goullet, P. J. Sansonetti, and J. Elion. 1993. Identification of a clone of Escherichia coli O103:H2 as a potential agent of hemolytic-uremic syndrome in France. J. Clin. Microbiol. 31:296-301.
28. McDaniel, T. K., K. G. Jarvis, M. S. Donnersberg, and J. B. Kaper. 1995. A genetic locus of enterocyte effacement conserved among diverse enterobacteria pathogens. Proc. Natl. Acad. Sci. USA 92:1664-1668.
29. Mühldorfer, I., and J. Hacker. 1994. Genetic aspects of Escherichia coli virulence. Microb. Pathog. 16:171-181.
30. Newland, J. W., N. A. Strockbine, S. F. Miller, A. D. O'Brien, and R. K. Holmes. 1985. Cloning of Shiga-like toxin structural genes from a toxin converting phage of Escherichia coli. Science 230:179-181.
31. Newland, J. W., N. A. Strockbine, and R. J. Neill. 1987. Cloning of genes for production of Escherichia coli Shiga-like toxin type II. Infect. Immun. 55: 2675-2680.
32. O'Brien, A. O., T. A. Lively, M. E. Chen, S. W. Rothman, and S. B. Formal. 1983. Escherichia coli O157:H7 strains associated with haemorrhagic colitis in the United States produce a Shigella dysenteriae 1 (SHIGA) like cytotoxin. Lancet 1:702.
33. O'Brien, A. D., J. W. Newland, S. F. Miller, R. K. Holmes, H. W. Smith, and S. B. Formal. 1984. Shiga-like toxin-converting phages from Escherichia coli strains that cause hemorrhagic colitis or infantile diarrhea. Science 226:694-696.
34. Pelludat, C., A. Rakin, C. A. Jacobi, S. Schubert, and J. Heesemann. 1998. The yersiniabactin biosynthetic gene cluster of Yersinia enterocolitica: organization and siderophore-dependent regulation. J. Bacteriol. 180:538-546.
35. Piérard, D., G. Muyldermans, L. Moriau, D. Stevens, and S. Lauwers. 1998. Identification of new verocytotoxin type 2 variant B-subunit genes in human and animal Escherichia coli isolates. J. Clin. Microbiol. 36:3317-3322.
36. Rakin, A., and J. Heesemann. 1995. Yersiniabactin/pesticin receptor: a component of an iron uptake system of highly pathogenic Yersinia. Contrib. Microbiol. Immunol. 13:244-247.
37. Rakin, A., P. Urbitsch, and J. Heesemann. 1995. Evidence for two evolutionary lineages of highly pathogenic Yersinia species. J. Bacteriol. 177:2292-2298.
38. Rakin, A., S. Schubert, C. Pelludat, D. Brem, and J. Heesemann. The high-pathogenicity island of Yersinia. In J. Kaper and J. Hacker (ed.), Pathogenicity islands and other mobile virulence elements, in press. ASM Press, Washington, D.C.
39. Rakin, A., C. Noelting, S. Schubert, and J. Heesemann. 1999. Common and specific characteristics of the high-pathogenicity island of Yersinia enterocolitica. Infect. Immun. 67:5265-5274.
40. Leu affects type 1 fimbriation in pathogenic Escherichia coli by control of FimB recombinase expression. Mol. Microbiol. 25:871-882.
41. Rüssmann, H., H. Schmidt, J. Heesemann, A. Caprioli, and H. Karch. 1994. Variants of Shiga-like toxin II constitute a major toxin component in Escherichia coli O157 strains from patients with haemolytic uraemic syndrome. J. Med. Microbiol. 40:338-343.
42. Rüssmann, H., E. Kothe, H. Schmidt, S. Franke, D. Harmsen, A. Caprioli, and H. Karch. 1995. Genotyping of Shiga-like toxin genes in non-O157 Escherichia coli strains associated with haemolytic uraemic syndrome. J. Med. Microbiol. 42:404-410.
43. Schmidt, H., B. Plaschke, S. Franke, H. Rüssmann, A. Schwarzkopf, J. Heesemann, and H. Karch. 1994. Differentiation of virulence patterns of Escherichia coli possessing eae genes. Med. Microbiol. Immunol. 183:23-31.
44. Schmidt, H., H. Rüssmann, A. Schwarzkopf, S. Aleksic, J. Heesemann, and H. Karch. 1994. Prevalence of attaching and effacing Escherichia coli in stool samples from patients and controls. Zentbl. Bakteriol. 281:201-213.
45. Schmidt, H., L. Beutin, and H. Karch. 1995. Molecular analysis of the plasmid-encoded hemolysin of Escherichia coli O157:H7 strain EDL933. Infect. Immun. 63:1055-1061.
46. Schmidt, H., J. Scheef, C. Janetzki-Mittermann, M. Datz, and H. Karch. 1997. An ileX tRNA gene is located close to the Shiga toxin II operon in enterohemorrhagic Escherichia coli O157 and non-O157 strains. FEMS Microbiol. Lett. 149:39-44.
47. Schmidt, H., C. Geitz, P. I. Tarr, M. Frosch, and H. Karch. 1999. Non-O157:H7 pathogenic Shiga toxin-producing Escherichia coli: phenotypic and genetic profiling of virulence traits and evidence for clonality. J. Infect. Dis. 179:115-123.
48. Schmitt, C. K., M. L. McKee, and A. D. O'Brien. 1991. Two copies of Shiga-like toxin II-related genes common in enterohemorrhagic Escherichia coli strains are responsible for the antigenic heterogeneity of the O157:H-strain E32511. Infect. Immun. 59:1065-1073.
49. Schubert, S., A. Rakin, H. Karch, E. Carniel, and J. Heesemann. 1998. Prevalence of the "high pathogenicity island" of Yersinia species among Escherichia coli strains that are pathogenic to humans. Infect. Immun. 66: 480-485.
50. Scotland, S. M., H. R. Smith, G. A. Willshaw, and B. Rowe. 1983. Vero cytotoxin production in strain of Escherichia coli is determined by genes carried on bacteriophage. Lancet 2:216.
51. Tarr, P. I., L. S. Fouser, A. E. Stapleton, R. A. Wilson, H. H. Kim, J. C. Vary, Jr., and C. R. Clausen. 1996. Hemolytic-uremic syndrome in a six-year-old girl after a urinary tract infection with Shiga-toxin-producing Escherichia coli O103:H2. N. Engl. J. Med. 335:635-638.
52. Tzipori, S., I. K. Wachsmuth, C. Chapman, R. Birner, J. Brittingham, C. Jackson, and J. Hogg. 1986. The pathogenesis of hemorrhagic colitis caused by Escherichia coli O157:H7 in gnotobiotic piglets. J. Infect. Dis. 154:712-716.
53. Vial, P. A., R. Robins-Browne, H. Lior, V. Prado, J. B. Kaper, J. P. Nataro, D. Maneval, A. Elsayed, and M. M. Levine. 1988. Characterization of enteroadherent-aggregative Escherichia coli, a putative agent of diarrheal disease. J. Infect. Dis. 158:70-79.
54. Wells, J. G., B. R. Davis, I. K. Wachsmuth, L. W. Riley, R. S. Remis, R. Sokolow, and G. K. Morris. 1983. Laboratory investigation of hemorrhagic colitis outbreaks associated with a rare Escherichia coli serotype. J. Clin. Microbiol. 18:512-520.