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Volumn 57, Issue 12, 2000, Pages 1695-1702

Transgenic mouse models and human neurodegenerative disorders

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; DEGENERATIVE DISEASE; GENE TARGETING; GENOME; MOUSE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; TECHNIQUE; TRANSGENIC MOUSE;

EID: 0033667504     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.57.12.1695     Document Type: Conference Paper
Times cited : (21)

References (36)
  • 4
    • 0030425881 scopus 로고    scopus 로고
    • Conditional mutagenesis in mice: The Cre/IoxP recombination system
    • (1996) Int J Exp Pathol , vol.77 , pp. 269-278
    • Pluck, A.1
  • 6
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3
  • 8
    • 15844393658 scopus 로고    scopus 로고
    • Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
    • (1996) Nat Genet , vol.13 , pp. 43-47
    • Reaume, A.G.1    Elliott, J.L.2    Hoffman3
  • 15
  • 18
    • 16044373842 scopus 로고    scopus 로고
    • Exon 1 of the H D gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
    • (1996) Cell , vol.87 , pp. 493-506
    • Mangiarini, L.1    Sathasivam, K.2    Seller, M.3
  • 22
    • 0032475931 scopus 로고    scopus 로고
    • Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
    • (1998) Cell , vol.95 , pp. 55-66
    • Saudou, F.1    Finkbeiner, S.2    Devys, D.3
  • 23
    • 0033391428 scopus 로고    scopus 로고
    • Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice
    • (1999) Neuron , vol.24 , pp. 879-892
    • Cummings, C.J.1    Reinstein, E.2    Sun, Y.3
  • 28
    • 16944362157 scopus 로고    scopus 로고
    • Mutant presenilins of Alzheimer's disease increase production of 42-residue amyioid beta-protein in both transfected cells and transgenic mice
    • (1997) Nat Meal , vol.3 , pp. 67-72
    • Citron, M.1    Westaway, D.2    Xia, W.3
  • 29
    • 0031914718 scopus 로고    scopus 로고
    • Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
    • (1998) Nat Med , vol.4 , pp. 97-100
    • Holcomb, L.1    Gordon, M.N.2    McGowan, E.3
  • 36
    • 0001552281 scopus 로고    scopus 로고
    • Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions
    • (1998) Cell , vol.93 , pp. 203-214
    • Shmerling, D.1    Hegyi, I.2    Fischer, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.