메뉴 건너뛰기




Volumn 391, Issue 6667, 1998, Pages 584-587

Pathogenesis of two axonopathies does not require axonal neurofilaments

Author keywords

[No Author keywords available]

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DEGENERATIVE DISEASE; DYSTONIA; GENE MUTATION; MOTOR NEURON DISEASE; MOUSE; NEUROFILAMENT; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

EID: 0032484934     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35378     Document Type: Article
Times cited : (86)

References (30)
  • 1
    • 0022871177 scopus 로고
    • Ballooned neurone in select neurodegenerative diseases contain phosphorylated neurofilament epitopes
    • Dickson, D. W. et al. Ballooned neurone in select neurodegenerative diseases contain phosphorylated neurofilament epitopes. Acta Neuropathol. 71, 216-223 (1986).
    • (1986) Acta Neuropathol. , vol.71 , pp. 216-223
    • Dickson, D.W.1
  • 2
    • 0022616904 scopus 로고
    • Cytoskeletal protein abnormalities in neurodegenerative diseases
    • Goldman, J. E. & Yen, S. H. Cytoskeletal protein abnormalities in neurodegenerative diseases. Ann. Neurol 19, 209-223 (1987).
    • (1987) Ann. Neurol , vol.19 , pp. 209-223
    • Goldman, J.E.1    Yen, S.H.2
  • 3
    • 0022758234 scopus 로고
    • 2,5-Hexanedione neuropathy is associated with covalent crosslinking of neurofilament proteins
    • Carden, M. J., Lee, V. M.-Y. & Schlaepfer, W. W. 2,5-Hexanedione neuropathy is associated with covalent crosslinking of neurofilament proteins. Neurochem. Pathol. 5, 25-35 (1986).
    • (1986) Neurochem. Pathol. , vol.5 , pp. 25-35
    • Carden, M.J.1    Lee, V.M.-Y.2    Schlaepfer, W.W.3
  • 4
    • 0024321887 scopus 로고
    • Effect of a single dose of β,β′ -Iminodipropionitrile in vivo on the properties of neurofilaments in vitro: Comparison with the effect of Imminodipropionitrile added directly to neurofilaments in vitro
    • Eyer, J., McLean, W. G. & Leterrier, J. F. Effect of a single dose of β,β′ -Iminodipropionitrile in vivo on the properties of neurofilaments in vitro: comparison with the effect of Imminodipropionitrile added directly to neurofilaments in vitro. J. Neurochem. 52, 1759-1765 (1989).
    • (1989) J. Neurochem. , vol.52 , pp. 1759-1765
    • Eyer, J.1    McLean, W.G.2    Leterrier, J.F.3
  • 6
    • 0025807172 scopus 로고
    • Epitopes located in spatially separate domains of each neurofilament subunit are present in Parkinson's disease Lewy body
    • Hill, W. D., Lee, V. M.-Y., Hurtig, H., Murray, J. M. & Trojanowski, J. Q. Epitopes located in spatially separate domains of each neurofilament subunit are present in Parkinson's disease Lewy body. J. Comp. Neurol. 109, 150-160 (1991).
    • (1991) J. Comp. Neurol. , vol.109 , pp. 150-160
    • Hill, W.D.1    Lee, V.M.-Y.2    Hurtig, H.3    Murray, J.M.4    Trojanowski, J.Q.5
  • 7
    • 0004008681 scopus 로고
    • (eds Spencer, P. & Schaumburg, H. H.) Williams and Wilkins, Baltimore
    • Griffin, J. W. & Price, D. L. in Experimental and Clinical Neurotoxicology (eds Spencer, P. & Schaumburg, H. H.) 161-178 (Williams and Wilkins, Baltimore, 1980).
    • (1980) Experimental and Clinical Neurotoxicology , pp. 161-178
    • Griffin, J.W.1    Price, D.L.2
  • 8
    • 0014336826 scopus 로고
    • Proximal axonal enlargement in motor neuron disease
    • Carpenter, S. Proximal axonal enlargement in motor neuron disease. Neurology 18, 841-851 (1968).
    • (1968) Neurology , vol.18 , pp. 841-851
    • Carpenter, S.1
  • 9
    • 0028063968 scopus 로고
    • Neurofilament function and dysfunction: Involvement in axonal growth and neuronal disease
    • Lee, M. K. & Cleveland, D. W. Neurofilament function and dysfunction: involvement in axonal growth and neuronal disease. Curr. Opin. Cell Biol 6, 34-40 (1994).
    • (1994) Curr. Opin. Cell Biol , vol.6 , pp. 34-40
    • Lee, M.K.1    Cleveland, D.W.2
  • 10
    • 0027465098 scopus 로고
    • Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis
    • Coté, F, Collard, J. F. & Julien, J. P. Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. Cell 73, 35-46 (1993).
    • (1993) Cell , vol.73 , pp. 35-46
    • Coté, F.1    Collard, J.F.2    Julien, J.P.3
  • 11
    • 0028116467 scopus 로고
    • A mutant neurofilament subunit causes massive, selective motor neuron death; implications for the pathogenesis of human motor neuron disease
    • Lee, M. K., Marszalek, J. R. & Cleveland, D.W. A mutant neurofilament subunit causes massive, selective motor neuron death; implications for the pathogenesis of human motor neuron disease. Neuron 13, 975-988 (1994).
    • (1994) Neuron , vol.13 , pp. 975-988
    • Lee, M.K.1    Marszalek, J.R.2    Cleveland, D.W.3
  • 12
    • 0027410516 scopus 로고
    • Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
    • Xu, Z. H., Cork, L. C., Griffin, J. W. & Cleveland, D. W. Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell 73, 23-33 (1993).
    • (1993) Cell , vol.73 , pp. 23-33
    • Xu, Z.H.1    Cork, L.C.2    Griffin, J.W.3    Cleveland, D.W.4
  • 13
    • 10244256425 scopus 로고    scopus 로고
    • Mechanisms of selective motor neurons death in transgenic mouse models of motor neuron disease
    • Cleveland, D. W. et al. Mechanisms of selective motor neurons death in transgenic mouse models of motor neuron disease. Neurology 47, 54-61 (1996).
    • (1996) Neurology , vol.47 , pp. 54-61
    • Cleveland, D.W.1
  • 14
    • 0030598838 scopus 로고    scopus 로고
    • An essential cytoskeletal linker protein connecting actin microfilaments ot intermediate filaments
    • Yang, Y. et al. An essential cytoskeletal linker protein connecting actin microfilaments ot intermediate filaments. Cell 86, 655-665 (1996).
    • (1996) Cell , vol.86 , pp. 655-665
    • Yang, Y.1
  • 15
    • 0029035706 scopus 로고
    • The mouse dystonia musculorum gene is a neural isoform of bullous pemphigoid antigen 1
    • Brown, A., Bernier, G., Mathieu, M., Rossant, J. & Kothary, R. The mouse dystonia musculorum gene is a neural isoform of bullous pemphigoid antigen 1. Nature Genet. 10, 301-306 (1995).
    • (1995) Nature Genet. , vol.10 , pp. 301-306
    • Brown, A.1    Bernier, G.2    Mathieu, M.3    Rossant, J.4    Kothary, R.5
  • 16
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn Superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen, D. R. et al. Mutations in Cu/Zn Superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59-62 (1993).
    • (1993) Nature , vol.362 , pp. 59-62
    • Rosen, D.R.1
  • 17
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong, P. C. et al. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14, 1105-1116 (1995).
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1
  • 18
    • 0028261670 scopus 로고
    • Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-β-galactosidase fusion protein
    • Eyer, J. & Peterson, A. C. Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-β-galactosidase fusion protein. Neuron 12, 389-405 (1994).
    • (1994) Neuron , vol.12 , pp. 389-405
    • Eyer, J.1    Peterson, A.C.2
  • 19
    • 0029557363 scopus 로고
    • Accelerated and widespread neuronal loss occurs in motor neuron degeneration (MND) mice expressing a neurofilament-disrupting transgene
    • Plummer, J., Peterson, A. & Messer, A. Accelerated and widespread neuronal loss occurs in motor neuron degeneration (MND) mice expressing a neurofilament-disrupting transgene. Mol. Cell. Neurosci. 6, 532-543 (1995).
    • (1995) Mol. Cell. Neurosci. , vol.6 , pp. 532-543
    • Plummer, J.1    Peterson, A.2    Messer, A.3
  • 20
    • 0030614372 scopus 로고    scopus 로고
    • Selective degeneration of Purkinje cells with Lewy body-like inclusions in aged NFHlacZ transgenic mice
    • Tu, P.-H. et al. Selective degeneration of Purkinje cells with Lewy body-like inclusions in aged NFHlacZ transgenic mice. J. Neurosci. 17, 1064-1074 (1997).
    • (1997) J. Neurosci. , vol.17 , pp. 1064-1074
    • Tu, P.-H.1
  • 21
    • 0029066406 scopus 로고
    • Gene targeting of BPAG1: Abnormalities in mechanical strength and cell migration in stratified squamos epithelia and severe neurologic degeneration
    • Guo, L. et al. Gene targeting of BPAG1: abnormalities in mechanical strength and cell migration in stratified squamos epithelia and severe neurologic degeneration. Cell 81, 233-243 (1995).
    • (1995) Cell , vol.81 , pp. 233-243
    • Guo, L.1
  • 22
    • 0016914818 scopus 로고
    • Dystonia musculorum: An inherited disease of the nervous system in the mouse
    • Duchen, L. W. Dystonia musculorum: an inherited disease of the nervous system in the mouse. Adv. Neurol 14, 353-365 (1976).
    • (1976) Adv. Neurol , vol.14 , pp. 353-365
    • Duchen, L.W.1
  • 23
    • 0023747623 scopus 로고
    • A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube
    • Kothary, R. et al. A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube. Nature 335, 435-437 (1988).
    • (1988) Nature , vol.335 , pp. 435-437
    • Kothary, R.1
  • 24
    • 0026630111 scopus 로고
    • An intrinsic neuronal defect operates in dystonia musculorum: A study of dt/dt ↔ +/+ chimeras
    • Campbell, R. M. & Peterson, A. C. An intrinsic neuronal defect operates in dystonia musculorum: a study of dt/dt ↔ +/+ chimeras. Neuron 9, 693-703 (1992).
    • (1992) Neuron , vol.9 , pp. 693-703
    • Campbell, R.M.1    Peterson, A.C.2
  • 25
    • 0023698294 scopus 로고
    • Pathologic changes in the CNS of dystonia musculorum mutant mouse: An animal model for human spinocerebellar ataxia
    • Sotelo, C. & Guenet, J. F. Pathologic changes in the CNS of dystonia musculorum mutant mouse: an animal model for human spinocerebellar ataxia. Neuroscience 27, 403-424 (1988).
    • (1988) Neuroscience , vol.27 , pp. 403-424
    • Sotelo, C.1    Guenet, J.F.2
  • 26
    • 0028284779 scopus 로고
    • Motor neuron degeneration in mice that express a human Cu, Zn Superoxide dismutase mutation
    • Gurney, M. E. et al. Motor neuron degeneration in mice that express a human Cu, Zn Superoxide dismutase mutation. Science 264, 1772-1775 (1994).
    • (1994) Science , vol.264 , pp. 1772-1775
    • Gurney, M.E.1
  • 28
    • 0029004898 scopus 로고
    • Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis
    • Collard, J.-F., Cote, F. & Julien, J. P. Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis. Nature 375, 61-64 (1995).
    • (1995) Nature , vol.375 , pp. 61-64
    • Collard, J.-F.1    Cote, F.2    Julien, J.P.3
  • 29
    • 0028001606 scopus 로고
    • Variant alleles of the neurofilament heavy gene associated with amyotrophic lateral sclerosis
    • Figlewicz, D. et al. Variant alleles of the neurofilament heavy gene associated with amyotrophic lateral sclerosis. Hum. Mol. Genet. 3, 1757-1761 (1994).
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 1757-1761
    • Figlewicz, D.1
  • 30
    • 0029970685 scopus 로고    scopus 로고
    • Sequence variants in human neurofilament proteins: Absence of linkage ot familial amyotrophic lateral sclerosis
    • Vechio, J., Bruijn, L., Brown, R. & Cleveland, D. Sequence variants in human neurofilament proteins: absence of linkage ot familial amyotrophic lateral sclerosis. Ann. Neurol. 40, 603-610 (1996).
    • (1996) Ann. Neurol. , vol.40 , pp. 603-610
    • Vechio, J.1    Bruijn, L.2    Brown, R.3    Cleveland, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.