Mouse genetics in cell biology

Experimental Physiology

Volumn 85, Issue 6, 2000, Pages 661-679

  Mansuy, I M ^a   Suter, U ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL GENETICS; ANIMAL MODEL; CARCINOGENESIS; CELL FUNCTION; CELL INTERACTION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOLOGY; DNA MODIFICATION; EXTRACELLULAR MATRIX; GENETIC MANIPULATION; GENETIC MODEL; HEREDITY; LEARNING; MEMORY; METHODOLOGY; MOLECULAR BIOLOGY; MOUSE; MYELINATION; NERVE CELL PLASTICITY; NEUROPATHY; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; REVIEW; SYNAPTIC TRANSMISSION;

EID: 0033665302     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-445X.2000.02098.x     Document Type: Review

References (169)

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4. Abnormal myelination in transplanted Trembler mouse Schwann cells
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6. Widespread expression of the peripheral myelin protein-22 gene (PMP22) in neural and non-neural tissues during murine development
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17. Genetic changes in skin tumor progression: Correlation between presence of a mutant Ras gene and loss of heterozygosity on mouse chromosome 7
18. A chimeric Cre recombinase inducible by synthetic, but not by natural ligands of the glucocorticoid receptor
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20. Localization and functional roles of PMP22 in peripheral nerves of PO-deficient mice
21. DNA deletion associated with hereditary neuropathy with liability to pressure palsies
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35. Ligand-activated site-specific recombination in mice
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37. Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death
38. Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control
39. Loss of distal axons and sensory Merkel cells and features indicative of muscle denervation in hindlimbs of PO-deficient mice
40. Two divergent types of nerve pathology in patients with different PO mutations in Charcot-Marie-Tooth disease
41. Multiple behavioral anomalies in GluR2 mutant mice exhibiting enhanced LTP
42. Mouse PO gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons
43. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
44. Transcriptional activation by tetracyclines in mammalian cells
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46. Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
47. PO and PMP22 mark a multipotent neural crest-derived cell type that displays community effects in response to TGF-beta family factors
48. Immunoreactivity of PMP-22, PO, and other 19 to 28 kDa glycoproteins in peripheral nerve myelin of mammals and fish with HNKl and related antibodies
49. Pathogenesis of Charcot-Marie-Tooth 1A (CMTIA) neuropathy
50. Ultrastructural distribution of PMP22 in Charcot-Marie-Tooth disease type lA
51. Cloned glutamate receptors
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53. Correlation between varying levels of PMP22 expression and the degree of demyelination and reduction in nerve conduction velocity in transgenic mice
54. Reduced spontaneous activity of mice defective in the 4 subunit of the NMDA receptor channel
55. Myelin deficiencies in both the central and the peripheral nervous systems associated with a SOX10 mutation
56. Dejerine-Sottas neuropathy in mother and son with same point mutation of PMP22 gene
57. Role of Oct-6 in Schwann cell differentiation
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59. Enhanced LTP in mice deficient in the AMPA receptor GluR2
60. Inducible genetic suppression of neuronal excitability
61. Expression and assembly of a human neurofilament protein in transgenic mice provides a novel neuronal marking system
62. The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function
63. Inducible site-specific recombination in the brain
64. Regulation of Cre recombinase activity by the synthetic steroid RU 486
65. Making of a Schwann
66. Increased thresholds for long-term potentiation and contextual learning in mice lacking the NMDA-type glutamate receptor epsilon1 subunit
67. Differential regulation of a Thy-1 gene in transgenic mice
68. Sox 10, a novel transcriptional modulator in glial cells
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70. Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice
71. Long-term synaptic depression
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77. Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory
78. Impaired differentiation of Schwann cells in transgenic mice with increased PMP22 gene dosage
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81. Formation and maintenance of the myelin sheath in the peripheral nerve: Roles of cell adhesion molecules and the gap junction protein commexin 32
82. Molecular bases of myelin formation as revealed by investigations on mice deficient in glial cell surface molecules
83. Protein zero (PO) deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies
84. A transgenic mouse model for human hereditary neuropathy with liability to pressure palsies
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87. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
88. Rescue of the cardiac defect in ErbB2 mutant mice reveals essential roles of ErbB2 in peripheral nervous system development
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92. Aberrant protein trafficking in Trembler suggests a disease mechanism for hereditary human peripheral neuropathies
93. Many facets of the peripheral myelin protein PMP22 in myelination and disease
94. Impaired intracellular trafficking is a common disease mechanism of PMP22 point mutations in peripheral neuropathies
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98. Altered molecular architecture of peripheral nerves in mice lacking the peripheral myelin protein 22 or connexin32
99. The zinc finger transcription factor Zif268/Egr-1 is essential for Schwann cell expression of the p75 NGF receptor
100. Ecdysone-inducible gene expression in mammalian cells and transgenic mice
101. PMP22 accumulation in aggresomes: Implications for CMTIA pathology
102. Upregulation of the endosomal-lysosomal pathway in the trembler-J neuropathy
103. Neurons promote the translocation of peripheral myelin protein 22 into myelin
104. Detection and processing of peripheral myelin protein PMP22 in cultured Schwann cells
105. PMP-22 expression in the central nervous system of the embryonic mouse defines potential transverse segments and longitudinal columns
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108. Regulation of protein function through expression of chimaeric proteins
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110. Role of axonal components during myelination
111. A recombination hotspot responsible for two inherited peripheral neuropathies is located near a mariner transposon-like element
112. Severe neuropathies in mice with targeted mutations in the ErbB3 receptor
113. Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit
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115. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1
116. Glycans and the modulation of neural-recognition molecule function
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119. The biology and pathobiology of Schwann cells
120. Connexin32 is a myelin-related protein in the PNS and CNS
121. RNA editing of brain glutamate receptor channels: Mechanisms and physiology
122. A transgenic rat model of Charcot-Marie-Tooth disease
123. Glial growth factor restricts mammalian neural crest stem cells to a glial fate
124. Crystal structure of the extracellular domain from PO, the major structural protein of peripheral nerve myelin
125. Axon-Schwann cell interactions regulate the expression of c-jun in Schwann cells
126. Signaling pathways mediating axon-Schwann cell interactions
127. Molecular anatomy and genetics of myelin proteins in the peripheral nervous system
128. Molecular basis of common hereditary motor and sensory neuropathies in humans and in mouse models
129. Human peripheral myelin protein-22 carries the L2/HNK-1 carbohydrate adhesion epitope
130. Characterization of a novel peripheral nervous system myelin protein (PMP-22/SR13)
131. The glycoprotein PO in peripheral gliogenesis
132. Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo
133. Axon-regulated expression of a Schwann cell transcript that is homologous to a 'growth arrest-specific' gene
134. Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans
135. Myelin glycolipids and their functions
136. Myelin: Keeping nerves well wrapped up
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138. A leucine-to-proline mutation in the putative first transmembrane domain of the 22-kDa peripheral myelin protein in the trembler-J mouse
139. Genetic basis of inherited peripheral neuropathies
140. Biology and genetics of hereditary motor and sensory neuropathies
141. Trembler mouse carries a point mutation in a myelin gene
142. Progress in the molecular understanding of hereditary peripheral neuropathies reveals new insights into the biology of the peripheral nervous system
143. Cell death in the Schwann cell lineage and its regulation by neuregulin
144. Genetic enhancement of learning and memory in mice
145. Molecular biology of axon-glia interactions in the peripheral nervous system
146. Epithelial membrane protein-1, peripheral myelin protein 22, and lens membrane protein 20 define a novel gene family
147. Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype
148. Transport of Trembler-J mutant peripheral myelin protein 22 is blocked in the intermediate compartment and affects the transport of the wild type protein by direct interaction
149. Alterations in gene expression associated with primary demyelination and remyelination in the peripheral nervous system
150. Krox-20 controls myelination in the peripheral nervous system
151. Hereditary neuromyotonia: A mouse model associated with deficiency or increased gene dosage of the PMP22 gene
152. Subregion- and cell type-restricted gene knockout in mouse brain
153. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory
154. Temporal, spatial, and cell type-specific control of Cre-mediated DNA recombination in transgenic mice
155. Identical point mutations of PMP-22 in Trembler-J mouse and Charcot-Marie-Tooth disease type 1a
156. Efficient expression of neurotransmitter receptors in mammalian cells: Use of inducible expression systems
157. Clinical phenotypes of different MPZ (PO) mutations may include Charcot-Marie-Tooth type 1B, Dejerine-Sottas, and congenital hypomyelination
158. Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies
159. A myelin protein is encoded by the homologue of a growth arrest-specific gene
160. Inherited recurrent neuropathy
161. Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin
162. Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development
163. Characterization of peripheral myelin protein 22 in zebrafish (zPMP22) suggests an early role in the development of the peripheral nervous system
164. Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and upregulation of TGFalpha expression in transgenic mice
165. Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning
166. Inducible site-directed recombination in mouse embryonic stem cells
167. Retroviral-mediated gene transfer of the peripheral myelin protein PMP22 in Schwann cells: Modulation of cell growth
168. Influence of elevated expression of rat wild-type PMP22 and its mutant PMP22Trembler on cell growth of NIH3T3 fibroblasts
169. Schwann cell differentiation