p38 Mitogen-activated protein kinase down-regulates nitric oxide and up- regulates prostaglandin E2 biosynthesis stimulated by interleukin-1β

Journal of Biological Chemistry

Volumn 272, Issue 12, 1997, Pages 8083-8089

  Guan, Zhonghong ^a   Baier, Lisa D ^a   Morrison, Aubrey R ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Box 8103 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PROSTAGLANDIN E2;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; HUMAN; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RAT; RNA ANALYSIS; SIGNAL TRANSDUCTION;

ANIMALS; BLOOD; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; GLOMERULAR MESANGIUM; INTERLEUKIN-1; ISOENZYMES; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXAZOLES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 0030951146     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.12.8083     Document Type: Article

References (19)

1. Oppenheim, J. J., Kovacs, E. J., Matsushima, K., and Durum, S. K. (1986) Immunol, Today 7, 44-45
2. Tetsuka, T., Daphna-Iken, D., Srivastava, S. K., Baier, L. D., Dumaine, J., and Morrison, A. R. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 12168-12172
3. Lowenstein, C. J., Glatt, C. S., Bredt, D. S., and Snyder, S. H. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 6711-6715
4. Lyons, C. R., Orloff, G. J., and Cunningham, J. M. (1992) J. Biol. Chem. 267, 6370-6374
5. Xie, Q. W., Cho, H. J., Calayeay, J., Mumford, R. A., Swiderek, K. M., Lee, T. D., Ding, A., Troso, T., and Nathan, C. (1992) Science 256, 225-228
6. Koide, M., Kawahara, Y., Nakayama, I., Tsuda, T., and Yokoyama, M. (1993) J. Biol. Chem. 268, 24959-24966
7. Nakayama, I., Kawahara, Y., Tsuda, T., Okuda, M., and Yokoyama, M. (1994) J. Biol. Chem. 269, 11628-11633
8. Pfeilschifter, J., Rob, P., Mulsch, A., Fandrey, J., Vosbeck, K., and Busse, R. (1992) Eur. J. Biochem. 203, 251-255
9. Nathan, C., and Xie, Q. (1994) J. Biol. Chem. 269, 13725-13728
10. Langenbach, R., Morham, S. G., Tiano, H. F., Loftin, C. D., Ghanayem, B. I., Chulada, P. C., Mahler, J. F., Lee, C. A., Goulding, E. H., Kluckman, K. D, Kim, H. S., and Smithies, O. (1995) Cell 83, 483-492
11. Morham, S. G., Langenbach, R., Loftin, C. D., Tiano, H. F., Vouloumanos, N., Jennette J. C., Mahler, J. F., Kluckman, K. D, Ledford, A., Lee, C. A., and Smithies, O. (1995) Cell 83, 473-482
12. Dinarello, C. A. (1994) FASEB J. 8, 1314-1325
13. Karnitz, L. M., and Abraham, R. T. (1995) Curr. Opin. Immunol. 7, 320-326
14. Davis, R. J. (1994) Trends Biochem. Sci. 19, 470-473
15. Cobb, M. H., and Goldsmith, E. J. (1995) J. Biol. Chem. 270, 14843-14846
16. Brewster, J. L., de Valoir, T., Dwyer, N. D., Winter, E., and Gustin, M. C. (1993) Science 259, 1760-1763
17. Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Llamazares, A., Zamanillo, D., Hurt, T., and Nebreda, A. (1994) Cell 78, 1027-1037
18. Freshney, N. W., Rawlinson, L., Guesdon, F., Jones, E., Cowley, S., Hsuan, J., and Saklatvala, J. (1994) Cell 78, 1039-1049
19. Knauf, U., Jakob, U., Engel, K, Buchner, J., and Gaestel, M. (1995) EMBO J. 13, 54-60