Estradiol protects against β-amyloid (25-35)-induced toxicity in SK-N-SH human neuroblastoma cells

Neuroscience Letters

Volumn 218, Issue 3, 1996, Pages 165-168

  Green, Pattie S ^a   Gridley, Kelly E ^a   Simpkins, James W ^a,b  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

Amyloid; Alzheimer's disease; Estradiol; Estrogens; SK N SH cells

Indexed keywords

AMYLOID BETA PROTEIN; ESTRADIOL; NEUROPROTECTIVE AGENT;

ALZHEIMER DISEASE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; NEUROBLASTOMA; NEUROTOXICITY; PRIORITY JOURNAL;

AMYLOID BETA-PROTEIN; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; HUMANS; NEUROBLASTOMA; NEUROPROTECTIVE AGENTS; NEUROTOXINS; PEPTIDE FRAGMENTS; TUMOR CELLS, CULTURED;

EID: 0030575880     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(96)13148-7     Document Type: Article

References (28)

1. [1] Behl, C., Davis, J., Cole, G.M. and Schubert, D., Vitamin E protects nerve cells from amyloid beta protein toxicity, Biochem. Biophys. Res. Commun., 186 (1992) 944-950.
2. [2] Behl, C., Widmann, M., Trapp, T. and Holsboer, F., 17-β Estradiol protects neurons from oxidative stress-induced cell death in vitro, Biochem. Biophys. Res. Commun., 216 (1995) 473-482.
3. [3] Bishop, J. and Simpkins, J.W., Estradiol treatment increases viability of glioma and neuroblastoma cells in vitro, Mol. Cell Neurosci., 5 (1994) 303-308.
4. [4] Black, L. and Berenbaum, M.C., Factors affecting the dye exclusion test for cell viability, Exp. Cell Res., 35 (1964) 9-13.
5. [5] Busciglio, J., Lorenzo, A. and Yankner, B.A., Methodological variables in the assessment of beta amyloid toxicity, Neurobiol. Aging, 13 (1992) 609-612.
6. [6] Games, D., Adams, D. and Alessandrine, R. et al., Alzheimer's-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein, Nature, 373 (1995) 523-527.
7. [7] Goodman, Y. and Mattson, M.P., Secreted forms of β-amyloid precursor protein protect hippocampal neurons against amyloid β-peptide-induced oxidative injury, Exp. Neurol., 128 (1994) 1-12.
8. [8] Goodman, Y., Bruce, A.J., Cheng, B. and Mattson, M.P., Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β-peptide toxicity in hippocampal neurons, J. Neurochem., 66 (1996) 1836-1844.
9. [9] Henderson, V.W., Paganini-Hill, A., Emanuel, C.K., Dunn, M.E. and Buckwalter, J.G., Estrogen replacement therapy in older women: comparisons between Alzheimer's disease cases and controls, Arch. Neurol., 51 (1994) 896-900.
10. [10] Hensley, K., Carney, J.M., Mattson, M.P., Askenova, M., Harris, M., Wu, J.F., Floyd, R.A. and Butterfield, D.A., A model for beta amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer's disease, Proc. Natl. Acad. Sci. USA, 91 (1994) 3270-3274.
11. [11] Jaffe, A.B., Toran-Allerand, C.D., Greengard, P. and Gandy, S.E., Estrogen regulates metabolism of Alzheimer amyloid β precursor protein, J. Biol. Chem., 269 (1994) 13065-13068.
12. [12] Koh, J.Y., Yang, L.L. and Cotman, C.W., β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage, Brain Res., 533 (1990) 315-320.
13. [13] Korenman, S.G., Comparative binding affinities of estrogens and its relation to estrogenic potency, Steroids, 13 (1969) 163-177.
14. [14] Mattson, M.P., Engle, M.G. and Rychlik, B., Effects of elevated intracellular calcium levels on the cytoskeleton and tau in cultured human cortical neurons, Mol. Chem. Neuropathol., 15 (1991) 117-142.
15. [15] Mattson, M.P., Tomaselli, K.J. and Rydel, R.E., Calcium-destabilizing and neurodegenerative effects of aggregated β-amyloid peptide are attenuated by basic FGF, Brain Res., 621 (1993) 35-49.
16. [16] Maury, C.P.J., Biology of disease: molecular pathogenesis of β-amyloidosis in Alzheimer's disease and other cerebral amyloidoses, Lab. Invest., 72 (1995) 4-16.
17. [17] Miranda, R.C., Sohrabji, F. and Toran-Allerand, C.D., Presumptive estrogen target neurons express mRNAs for both the neurotrophins and neurotrophin receptors: a basis for potential development interactions of estrogen with the neurotrophins, Mol. Cell Neurosci., 4 (1993) 510-525.
18. [18] Mukai, K., Daifuku, K., Yokoyama, S. and Nakano, M., Stopped-flow investigation of antioxidant activity of estrogens in solution, Biochim. Biophys. Acta, 1035 (1990) 348-352.
19. [19] Paganini-Hill, A. and Henderson, V.W., Estrogen deficiency and risk of Alzheimer's disease, Am. J. Epidemiol., 140 (1994) 256-261.
20. [20] Pike, C.J., Walencewicz, A.J., Glabe, C.G. and Cotman, C.W., In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity, Brain Res., 563 (1991) 311-314.
21. [21] Simpkins, J.W., Green, P.S., Bishop, J. and Turner, N., 17 α-estradiol exerts neuroprotective effects on SK-N-SH cells, Soc. Neurosci. Abstr., 21 (1995) 1979.
22. [22] Simpkins, J.W., Green, P.S., Gridley, K.E., Singh, M., deFiebre, N.C. and Rajakumar, G., Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease, Am. J. Med. (1996) in press.
23. [23] Simpkins, J.W., Singh, M. and Bishop, J., The potential role for estrogen-replacement therapy in the treatment of the cognitive decline and neurodegeneration associated with Alzheimer's disease, Neurobiol. Aging, 15 (1994) S195-S197.
24. [24] Singer, C.A., Strickland, T.M., Rogers, K.L. and Dorsa, D.M., Estrogen protects primary cortical neurons from glutamate neurotoxicity, Soc. Neurosci. Abstr., 21 (1995) 882.
25. [25] Singh, M., Meyer, E.M. and Simpkins, J.W., The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats, Endocrinology, 136 (1995) 2320-2324.
26. [26] Sugioka, K., Shimosegawa, Y. and Natano, M., Estrogens as natural antioxidants of membrane phospholipid peroxidation, FEBS Lett., 210 (1987) 37-39.
27. [27] Yankner, B.A., Dawes, L.R., Fisher, S., Villa-Komaroff, L., Oster-Granite, M.L. and Neve, R.L., Neurotoxicity of fragment of the amyloid precursor associated with Alzheimer's disease, Science, 245 (1989) 417-420.
28. [28] Yankner, B.A., Duffy, L.K. and Kirschner, D.A., Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides, Science, 250 (1990) 279-282.