Lipopolysaccharide modulates cyclooxygenase-2 transcriptionally and posttranscriptionally in human macrophages independently from endogenous IL- 1β and TNF-α

Journal of Immunology

Volumn 163, Issue 2, 1999, Pages 963-969

  Barrios Rodiles, Miriam ^a   Tiraloche, Gabrielle ^a   Chadee, Kris ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; DACTINOMYCIN; DEXAMETHASONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROSTAGLANDIN; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ENZYME REGULATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MACROPHAGE; MACROPHAGE FUNCTION; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; SEPTICEMIA;

EID: 0033565430     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Dal Nogare, A. R. 1991. Southwestern internal medicine conference: septic shock. Am. J. Med. Sci. 302:50.
2. Vane, J. R., and R. M. Botting. 1995. New insights into the mode of action of anti-inflammatory drugs. Inflamm. Res. 44:1.
3. Cao, Ch., K. Matsumura, K. Yamagata, and Y. Watanabe. 1997. Involvement of cyclooxygenase-2 in LPS-induced fever and regulation of its mRNA by LPS in the rat brain. Am. J. Physiol. 272:R1712.
4. Hussain, S. N. A. 1998. Respiratory muscle dysfunction in sepsis. Mol. Cell. Biochem. 179:125.
5. O'Neill, G. P., and A. W. Ford-Hutchinson. 1993. Expression of mRNA for cyclooxygenase-1 and cylcooxygenase-2 in human tissues. FEBS Lett. 330:156.
6. Habib, A., C. Creminon, Y. Frobert, J. Grassi, P. Pradelles, and J. Maclouf. 1993. Demonstration of an inducible cyclooxygenase in human endothetial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2. J. Biol. Chem. 268:23448.
7. O'Banion, K. M., V. D. Winn, and D. A. Young. 1992. cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc. Natl. Acad. Sci. USA 89:4888.
8. Ristimaki, A., S. Garfinkel, J. Wessendorf, T. Maciag, and T. Hla. 1994. Induction of cyclooxygenase-2 by interleukin-1α. J. Biol. Chem. 269:11769.
9. 2 formation. J. Biol. Chem. 271:31496.
10. Tetsuka, T., D. Daphna-Iken, B. W. Miller, Z. Guan, L. D. Baier, and A. Morrison, 1996. Nitric oxide amplifies interleukin-1-induced cyclooxygenase-2 expression in rat mesangial cells. J. Clin. Invest. 97:2051.
11. Yamamoto, K., T. Arakawa, N. Ueda, and S. Yamamoto. 1995. Transcriptional roles of nuclear factor κB and nuclear factor-interleukin-6 in the tumor necrosis factor α-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells. J. Biol. Chem. 270:31315.
12. Akarasereenont, P., Y. S. Bakhle, C. Thiemermann, and J. R. Vane. 1995. Cytokine-mediated induction of cyclooxygenase-2 by activation of tyrosine kinase in bovine endothelial cells stimulated by bacterial lipopdysaccharide. Br. J. Pharmacol. 115:401.
13. Glaser, K. B., and Y. W. Lock. 1995. Regulation of prostaglandin H synthase 2 expression in human monocytes by the marine natural products monoalide and scalardial: novel effects independent of inhibition of lipid mediator production. Biochem. Pharmacol. 50:913.
14. Young, H., and K. J. Hardy. 1995. Role of interferon-γ in immune cell regulation. J. Leukocyte Biol. 58:373.
15. Riesse, S., T. Hoff, A. Nordhoff, D. L. De Witt, K. Resch, and V. Kaever. 1994. Transient expression of prostaglandin endoperoxide synthase-2 during mouse macrophage activation. J. Leukocyte Biol. 55:477.
16. Endo, T., F. Ogushi, and S. Sone. 1996. LPS-dependent cyclooxygenase-2 induction in human monocytes is down-regulated by IL-13, but not by IFN-γ. J. Immunol. 156:2240.
17. 2 production by IFN-γ in human macrophages. J. Immunol. 161:2441.
18. Newton, R., L. M. E. Kuitert, M. Bergmann, I. M. Adcock, and P. J. Bames. 1997. Evidence for the involvement of NF-κB in the transcriptional control of COX-2 gene expression by IL-1β. Biochem. Biophys. Res. Commun. 237:28.
19. Srivastava, S., T. Telsuka, D. Daphna-Iken, and A. R. Morrison. 1994. 1L-1β stabilizes COX II mRNA in renal mesangial cells: role of 3′-unstranslated region. Am. J. Physiol. 267:F504.
20. Gou, Q., C. H. Liu, P. Ben-Av, and T. Hla. 1998. Dissociation of basal turnover and cytokine-induced transcript stabilization of the human cyclooxygenase-2 mRNA by mutagenesis of the 3′-untranslated region. Biochem. Biophys. Res. Commun. 242:508.
21. Crofford, L. J., B. Tan, C. J. McCarthy and T. Hla. 1997. Involvement of nuclear factorκB in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes. Arthritis Rheum. 40:226.
22. Inoue, H., and T. Tanabe. 1998. Transcriptional role of the nuclear factor κB site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells. Biochem. Biophys. Res. Commun. 244:143.
23. D'Acquisto, F., T. Iuvone, L. Rombola, L. Sautebin, M. Di Rosa, and R. Carnuccio. 1997. Involvement of NF-κB in the regulation of cyclooxygenase-2 protein expression in LPS-stimulated J774 macrophages. FEBS Lett. 418: 175.
24. Tada, H., O. Shiho, K. Kuroshima, M. Koyama, and K. Tsukamoto. 1986. An improved colorimetric assay for interleukin 2. J. Immunol. Methods 93:157.
25. Muroi, M., Y. Muroi, K. Yamamoto, and T. Suzuki. 1993. Influence of 3′ half-site sequence of NF-κB motifs on the binding of lipopolysaccharide-activable macrophage NF-κB proteins. J. Biol. Chem. 268:19534.
26. Zhang, X., V. E. Laubach, E. W. Alley, K. A. Edwards, P. A. Sherman, S. W. Russell, and W. J. Murphy. 1996. Transcriptional basis for hyporesponsiveness of the human inducible nitric oxide synthase gene to lipopolysaccharide/ interferon-γ. J. Leukocyte Biol. 59:575.
27. Roberts, F. A., G. J. Richardson, and S. M. Michalek, 1997. Effects of Porphyromonas gingivalis and Escherichia coli lipopolysaccharides on mononuclear phagocytes. Infect. Immun. 65:3248.
28. Ristimaki, A., K. Narko, and T. Hla. 1996. Down-regulation of cytokine-induced cyclooxygenase-2 transcripts isoforms by dexamethasone: evidence for post-transcriptional regulation. Biochem. J. 318:325.
29. Arias-Negrete, S., K. Keller, and K. Chadee. 1995. Proinflammatory cytokines regulate cyclooxygenase-2 mRNA expression in human macrophages. Biochem. Biophys. Res. Commun. 208:582.
30. Naraba, H., M. Murakami, H. Matsumoto, S. Shimbara, A. Ueno, I. Kudo, and S. Oh-ishi. 1998. Segregated coupling of phospholipases A2, cyclooxygenases, and terminal prostanoid synthases in different phases of prostanoid biosynthesis in rat peritoneal macrophages. J. Immunol. 160:2974.
31. 2 generation in rat 3Y1 fibroblasts. J. Biol. Chem. 273:1733.
32. Fournier, T., V. Fadok, and P. M. Henson. 1997. Tumor necrosis factor-production in murine macrophages. J. Biol. Chem. 272:31065.
33. Topley, N., M. M. Petersen, R. Mackenzie, A. Neubauer, E. Stylianou, V. Kaever, M. Davies, G. A. Coles, A. Jorres, and J. D. Williams. 1994. Human peritoneal mesothelial cell prostaglandin synthesis: induction of cyclooxygenase mRNA by peritoneal macrophage-derived cytokines. Kidney Int. 46:900.
34. Alaaeddine, A., J. A. DiBattista, J.-P. Pelletier, J.-M. Cloutier, K. Kiansa, M. Dupuis, and J. Martel-Pelletier. 1997. Osteoarthritic synovial fibroblasts possess an increased level of tumor necrosis factor-receptor 55 (TNF-R55) that mediates biological activation by TNF-α. J. Rheumatol. 24:1985.
35. Pouliot, M., J. Baillargeon, J. C., Lee, L. G. Cleland, and M. J. James. 1997. Inhibition of prostaglandin endoperoxide synthase-2 expression in stimulated human monocytes by inhibitors of p38 mitogen-activated piotein kinase. J. Immunol. 158: 4930.
36. Yamaoka, K., T. Otsuka, H. Niiro, Y. Arinobu, Y. Niho, N. Hamasaki, and K. Izuhara. 1998. Activation of STATS by lipopolysaccharide through granulocyte-macrophage colony-stimulating factor production in human monocytes. J. Immunol. 160:838.
37. Inoue, H., C. Yokoyama, S. Hara, Y. Tone, and T. Tanabe. 1995. Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. J. Biol. Chem. 270:24965.
38. Fletcher, B. S., D. A. Kujubu, D. M. Perrin, and H. R. Herschman. 1992. Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10 encoded protein is a functional prostaglandin G/H synthase. J. Biol. Chem. 267:438.
39. Hla, T., and K. Neilson. 1992. Human cyclooxygenase-2 cDNA. Proc. Natl. Acad. Sci. USA 89:7384.
40. Appleby, S. B., A. Ristimaki, K. Neilson, K. Narko, and T. Hla. 1994. Structure of the human cyclo-oxygenase-2 gene. Biochem. J. 302:723.
41. Shawn, G., and R. Kamen. 1986. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659.
42. Greenberg, M. E., A.-B. Shyu, and J. G. Belasco. 1990. Deadenylation: a mechanism controlling c-fos mRNA decay. Enzyme 44:181.
43. Malter, J. S. 1989. Identification of an AUUUA-specific messenger RNA binding protein. Science 246:664.
44. Zaidi, S. H. E., and J. S. Malter. 1995. Nucleolin and heterogeneous nuclear ribonucleoprotein C proteins specifically interact with the 3′-untranslated region of amyloid protein precursor mRNA. J. Biol. Chem. 270:17292.
45. Fan, X. C., and J. A. Steitz. 1998. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J. 17:3448.
46. Stacey, K. J., Y. Nagamine, and D. A. Hume. 1994. RNA synthesis inhibition stabilises urokinase mRNA in macrophages. FEBS Lett. 356:311.
47. Rajagopalan, L. E., and J. S. Malter. 1996. Turnover and translation of in vitro synthesized messenger RNAs in transfected, normal cells. J. Biol. Chem. 271:19871.
48. 2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA. J. Biol. Chem. 273:32312.