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Volumn 186, Issue 2, 1997, Pages 221-228

Itk negatively regulates induction of T cell proliferation by CD28 costimulation

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; INTERLEUKIN 2; PROTEIN TYROSINE KINASE;

EID: 0030852623     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.186.2.221     Document Type: Article
Times cited : (46)

References (51)
  • 3
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss, A., and D.R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell. 76:263-274.
    • (1994) Cell , vol.76 , pp. 263-274
    • Weiss, A.1    Littman, D.R.2
  • 4
    • 0026691651 scopus 로고
    • CD28-induced T cell activation. Evidence for a protein-tyrosine kinase signal transduction pathway
    • Lu, Y., A. Granelli-Piperno, J.M. Bjorndahl, C.A. Phillips, and J.M. Trevillyan. 1992. CD28-induced T cell activation. Evidence for a protein-tyrosine kinase signal transduction pathway. J. Immunol. 149:24-29.
    • (1992) J. Immunol. , vol.149 , pp. 24-29
    • Lu, Y.1    Granelli-Piperno, A.2    Bjorndahl, J.M.3    Phillips, C.A.4    Trevillyan, J.M.5
  • 6
    • 0028203261 scopus 로고
    • Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins
    • Hutchcroft, J.E., and B.E. Bierer. 1994. Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins. Proc. Natl. Acad. Sci. USA. 91: 3260-3264.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3260-3264
    • Hutchcroft, J.E.1    Bierer, B.E.2
  • 7
    • 0027086431 scopus 로고
    • CD28 receptor crosslinking induces tyrosine phosphorylation of PLCγ1
    • Ledbetter, J.A., and P.S. Linsley. 1992. CD28 receptor crosslinking induces tyrosine phosphorylation of PLCγ1. Adv. Exp. Med. Biol. 323:23-27.
    • (1992) Adv. Exp. Med. Biol. , vol.323 , pp. 23-27
    • Ledbetter, J.A.1    Linsley, P.S.2
  • 9
    • 0023017930 scopus 로고
    • Antibody binding to CD5 (Tp67) and Tp44 T cell surface molecules: Effects on cyclic nucleotides, cytoplasmic free calcium, and cAMP-mediated suppression
    • Ledbetter, J.A., M. Parsons, P.J. Martin, J.A. Hansen, P.S. Rabinovitch, and C.H. June. 1986. Antibody binding to CD5 (Tp67) and Tp44 T cell surface molecules: effects on cyclic nucleotides, cytoplasmic free calcium, and cAMP-mediated suppression. J. Immunol. 137:3299-3305.
    • (1986) J. Immunol. , vol.137 , pp. 3299-3305
    • Ledbetter, J.A.1    Parsons, M.2    Martin, P.J.3    Hansen, J.A.4    Rabinovitch, P.S.5    June, C.H.6
  • 10
    • 0022458229 scopus 로고
    • Synergy between the T3/antigen receptor complex and Tp44 in the activation of human T cells
    • Weiss, A., B. Manger, and J. Imboden. 1986. Synergy between the T3/antigen receptor complex and Tp44 in the activation of human T cells. J. Immunol. 137:819-825.
    • (1986) J. Immunol. , vol.137 , pp. 819-825
    • Weiss, A.1    Manger, B.2    Imboden, J.3
  • 11
    • 0027320758 scopus 로고
    • Signalling through CD28 T-cell activation pathway involves an inositol phospholipid-specific phospholipase C activity
    • Nunes, J., S. Klasen, M.D. Franco, C. Lipcey, C. Mawas, M. Bagnasco, and D. Olive. 1993. Signalling through CD28 T-cell activation pathway involves an inositol phospholipid-specific phospholipase C activity. Biochem. J. 293:835-842.
    • (1993) Biochem. J. , vol.293 , pp. 835-842
    • Nunes, J.1    Klasen, S.2    Franco, M.D.3    Lipcey, C.4    Mawas, C.5    Bagnasco, M.6    Olive, D.7
  • 12
    • 0024546328 scopus 로고
    • Enhanced transmembrane signalling activity of monoclonal antibody heteroconjugates suggests molecular interactions between receptors on the T cell surface
    • Ledbetter, J.A., N.A. Norris, A. Grossmann, L.S. Grosmaire, C.H. June, F.M. Uckun, W.L. Cosand, and P.S. Rabinovitch. 1989. Enhanced transmembrane signalling activity of monoclonal antibody heteroconjugates suggests molecular interactions between receptors on the T cell surface. Mol. Immunol. 26:137-145.
    • (1989) Mol. Immunol. , vol.26 , pp. 137-145
    • Ledbetter, J.A.1    Norris, N.A.2    Grossmann, A.3    Grosmaire, L.S.4    June, C.H.5    Uckun, F.M.6    Cosand, W.L.7    Rabinovitch, P.S.8
  • 14
    • 0028221022 scopus 로고
    • T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif
    • Prasad, K.V., Y.C. Cai, M. Raab, B. Duckworth, L. Cantley, S.E. Shoelson, and C.E. Rudd. 1994. T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif. Proc. Natl. Acad. Sci. USA. 91:2834-2838.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2834-2838
    • Prasad, K.V.1    Cai, Y.C.2    Raab, M.3    Duckworth, B.4    Cantley, L.5    Shoelson, S.E.6    Rudd, C.E.7
  • 15
    • 0028118512 scopus 로고
    • Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells
    • Truitt, K.E., C.M. Hicks, and J.B. Imboden. 1994. Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells. J. Exp. Med. 179:1071-1076.
    • (1994) J. Exp. Med. , vol.179 , pp. 1071-1076
    • Truitt, K.E.1    Hicks, C.M.2    Imboden, J.B.3
  • 16
    • 0028211126 scopus 로고
    • The cytoplasmic domain ot CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3′-kinase
    • Stein, P.H., J.D. Fraser, and A. Weiss. 1994. The cytoplasmic domain ot CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3′-kinase. Mol. Cell. Biol. 14:3392-3402.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3392-3402
    • Stein, P.H.1    Fraser, J.D.2    Weiss, A.3
  • 17
    • 0027940531 scopus 로고
    • CD28 signal transduction: Tyrosine phosphorylation and receptor association of phosphoinositide-3 kinase correlate with Ca(2+)-independent costimulatory activity
    • Lu, Y., C.A. Phillips, J.M. Bjorndahl, and J.M. Trevillyan. 1994. CD28 signal transduction: tyrosine phosphorylation and receptor association of phosphoinositide-3 kinase correlate with Ca(2+)-independent costimulatory activity. Eur. J. Immunol. 24:2732-2739.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2732-2739
    • Lu, Y.1    Phillips, C.A.2    Bjorndahl, J.M.3    Trevillyan, J.M.4
  • 18
    • 0028956419 scopus 로고
    • Phosphatidylinositol 3-kinase activity is not essential for CD28 costimulatory activity in Jurkat T cells: Studies with a selective inhibitor, wortmannin
    • Lu, Y., C.A. Phillips, and J.M. Trevillyan. 1995. Phosphatidylinositol 3-kinase activity is not essential for CD28 costimulatory activity in Jurkat T cells: studies with a selective inhibitor, wortmannin. Eur. J. Immunol. 25:533-537.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 533-537
    • Lu, Y.1    Phillips, C.A.2    Trevillyan, J.M.3
  • 19
    • 0028940428 scopus 로고
    • Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin
    • Ward, S.G., A. Wilson, L. Turner, J. Westwick, and D.M. Sansom. 1995. Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin. Eur. J. Immunol. 25:526-532.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 526-532
    • Ward, S.G.1    Wilson, A.2    Turner, L.3    Westwick, J.4    Sansom, D.M.5
  • 20
    • 0028972712 scopus 로고
    • CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation
    • Crooks, M.E., D.R. Littman, R.H. Carter, D.T. Fearon, A. Weiss, and P.H. Stein. 1995. CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation. Mol. Cell. Biol. 15:6820-6828.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6820-6828
    • Crooks, M.E.1    Littman, D.R.2    Carter, R.H.3    Fearon, D.T.4    Weiss, A.5    Stein, P.H.6
  • 21
    • 0028802706 scopus 로고
    • Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation
    • Cai, Y.C., D. Cefai, H. Schneider, M. Raab, N. Nabavi, and C.E. Rudd. 1995. Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation. Immunity. 3:417-426.
    • (1995) Immunity , vol.3 , pp. 417-426
    • Cai, Y.C.1    Cefai, D.2    Schneider, H.3    Raab, M.4    Nabavi, N.5    Rudd, C.E.6
  • 22
    • 0028972549 scopus 로고
    • CD28 delivers costimulatory signals independently of its association with phosphatidylinositol 3-kinase
    • Truitt, K.E., J. Shi, S. Gibson, L.G. Segal, G.B. Mills, and J.B. Imboden. 1995. CD28 delivers costimulatory signals independently of its association with phosphatidylinositol 3-kinase. J. Immunol. 155:4702-4710.
    • (1995) J. Immunol. , vol.155 , pp. 4702-4710
    • Truitt, K.E.1    Shi, J.2    Gibson, S.3    Segal, L.G.4    Mills, G.B.5    Imboden, J.B.6
  • 23
    • 0027393602 scopus 로고
    • Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk
    • Heyeck, S.D., and L.J. Berg. 1993. Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk. Proc. Natl. Acad. Sci. USA. 90:669-673.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 669-673
    • Heyeck, S.D.1    Berg, L.J.2
  • 24
    • 0026453395 scopus 로고
    • itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2
    • Siliciano, J.D., T.A. Morrow, and S.V. Desiderio. 1992. itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2. Proc. Natl. Acad. Sci. USA. 89:11194-11198.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11194-11198
    • Siliciano, J.D.1    Morrow, T.A.2    Desiderio, S.V.3
  • 26
    • 0027217937 scopus 로고
    • Identification, cloning, and characterization of a novel human T-cell-specific tyrosine kinase located at the hematopoietin complex on chromosome 5q
    • Gibson, S., B. Leung, J.A. Squire, M. Hill, N. Arima, P. Goss, D. Hogg, and G.B. Mills. 1993. Identification, cloning, and characterization of a novel human T-cell-specific tyrosine kinase located at the hematopoietin complex on chromosome 5q. Blood. 82:1561-1572.
    • (1993) Blood , vol.82 , pp. 1561-1572
    • Gibson, S.1    Leung, B.2    Squire, J.A.3    Hill, M.4    Arima, N.5    Goss, P.6    Hogg, D.7    Mills, G.B.8
  • 27
    • 13344270890 scopus 로고
    • Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk
    • Liao, X.C., and D.R. Littman. 1995. Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk. Immunity. 3:757-769.
    • (1995) Immunity , vol.3 , pp. 757-769
    • Liao, X.C.1    Littman, D.R.2
  • 28
    • 0028146530 scopus 로고
    • CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line
    • August, A., S. Gibson, Y. Kawakami, T. Kawakami, G.B. Mills, and B. Dupont. 1994. CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line. Proc. Natl. Acad. Sci. USA. 91:9347-9351.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9347-9351
    • August, A.1    Gibson, S.2    Kawakami, Y.3    Kawakami, T.4    Mills, G.B.5    Dupont, B.6
  • 29
    • 0026537347 scopus 로고
    • CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
    • Harding, F.A., J.G. McArthur, J.A. Gross, D.H. Raulet, and J.P. Allison. 1992. CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature (Lond.). 356:607-609.
    • (1992) Nature (Lond.) , vol.356 , pp. 607-609
    • Harding, F.A.1    McArthur, J.G.2    Gross, J.A.3    Raulet, D.H.4    Allison, J.P.5
  • 30
    • 0029120245 scopus 로고
    • CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
    • Krummel, M.F., and J.P. Allison. 1995. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182:459-465.
    • (1995) J. Exp. Med. , vol.182 , pp. 459-465
    • Krummel, M.F.1    Allison, J.P.2
  • 31
    • 0026649765 scopus 로고
    • Identification and distribution of the costimulatory receptor CD28 in the mouse
    • Gross, J.A., E. Callas, and J.P. Allison. 1992. Identification and distribution of the costimulatory receptor CD28 in the mouse. J. Immunol. 149:380-388.
    • (1992) J. Immunol. , vol.149 , pp. 380-388
    • Gross, J.A.1    Callas, E.2    Allison, J.P.3
  • 33
    • 0029953858 scopus 로고    scopus 로고
    • CTLA-4 ligation blocks CD28-dependent T cell activation
    • Walunas, T.L., C.Y. Bakker, and J.A. Bluestone. 1996. CTLA-4 ligation blocks CD28-dependent T cell activation. J. Exp. Med. 183:2541-2550.
    • (1996) J. Exp. Med. , vol.183 , pp. 2541-2550
    • Walunas, T.L.1    Bakker, C.Y.2    Bluestone, J.A.3
  • 34
    • 0029899783 scopus 로고    scopus 로고
    • CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
    • Krummel, M.F., and J.P. Allison. 1996. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J. Exp. Med. 183:2533-2540.
    • (1996) J. Exp. Med. , vol.183 , pp. 2533-2540
    • Krummel, M.F.1    Allison, J.P.2
  • 35
    • 0028979466 scopus 로고
    • New perspectives of CD28-B7-mediated T cell costinuilation
    • Bluestone, J.A. 1995. New perspectives of CD28-B7-mediated T cell costinuilation. Immunity. 2:555-559.
    • (1995) Immunity , vol.2 , pp. 555-559
    • Bluestone, J.A.1
  • 37
    • 0027515034 scopus 로고
    • Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human gamma 1
    • Lane, P., W. Gerhard, S. Hubele, A. Lanzavecchia, and F. McConnell. 1993. Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human gamma 1. Immunology. 80:56-61.
    • (1993) Immunology , vol.80 , pp. 56-61
    • Lane, P.1    Gerhard, W.2    Hubele, S.3    Lanzavecchia, A.4    McConnell, F.5
  • 38
    • 0023637951 scopus 로고
    • T-cell proliferation involving the CD28 pathway is associated with cyclosponne-resistant interleukin 2 gene expression
    • June, C.H., J.A. Ledbetter, M.M. Gillespie, T. Lindsten, and C.B. Thompson. 1987. T-cell proliferation involving the CD28 pathway is associated with cyclosponne-resistant interleukin 2 gene expression. Mol. Cell Biol. 7:4472-4481.
    • (1987) Mol. Cell Biol. , vol.7 , pp. 4472-4481
    • June, C.H.1    Ledbetter, J.A.2    Gillespie, M.M.3    Lindsten, T.4    Thompson, C.B.5
  • 40
    • 0024317711 scopus 로고
    • Evidence for the involvement of three distinct signals of IL-2 gene expression in human T lymphocytes
    • June, C.H., J.A. Ledbetter, T. Lindsten, and C.B. Thompson. 1989. Evidence for the involvement of three distinct signals of IL-2 gene expression in human T lymphocytes. J. Immunol. 143:153-161.
    • (1989) J. Immunol. , vol.143 , pp. 153-161
    • June, C.H.1    Ledbetter, J.A.2    Lindsten, T.3    Thompson, C.B.4
  • 41
    • 0024506159 scopus 로고
    • Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway
    • Lindsten, T., C.H. June, J.A. Ledbetter, G. Stella, and C.B. Thompson. 1989. Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. Science (Wash. DC). 244:339-343.
    • (1989) Science (Wash. DC) , vol.244 , pp. 339-343
    • Lindsten, T.1    June, C.H.2    Ledbetter, J.A.3    Stella, G.4    Thompson, C.B.5
  • 42
    • 43949164661 scopus 로고
    • Signal transduction events leading to T-cell lymphokine gene expression
    • Fraser, J.D., D. Straus, and A. Weiss. 1993. Signal transduction events leading to T-cell lymphokine gene expression. Immunol. Today. 14:357-362.
    • (1993) Immunol. Today , vol.14 , pp. 357-362
    • Fraser, J.D.1    Straus, D.2    Weiss, A.3
  • 45
    • 0029989312 scopus 로고    scopus 로고
    • Functional Lck is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ ITK
    • Gibson, S., A. August, D. Branch, B. Dupont, and G.B. Mills. 1996. Functional Lck is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ ITK. J. Biol. Chem. 271:7079-7083.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7079-7083
    • Gibson, S.1    August, A.2    Branch, D.3    Dupont, B.4    Mills, G.B.5
  • 46
    • 0028291525 scopus 로고
    • JNK is involved in signal integration during costimulation of T lymphocytes
    • Su, B., E. Jacinto, M. Hibi, T. Kallunki, M. Karin, and Y. Ben-Neriah. 1994. JNK is involved in signal integration during costimulation of T lymphocytes. Cell. 77:727-736.
    • (1994) Cell , vol.77 , pp. 727-736
    • Su, B.1    Jacinto, E.2    Hibi, M.3    Kallunki, T.4    Karin, M.5    Ben-Neriah, Y.6
  • 47
    • 0027291690 scopus 로고
    • Medullary thymic epithelium expresses a ligand for CTLA4 in situ and in vitro
    • Nelson, A.J., S. Hosier, W. Brady, P.S. Linsley, and A.G. Farr. 1993. Medullary thymic epithelium expresses a ligand for CTLA4 in situ and in vitro. J. Immunol. 151:2453-2461.
    • (1993) J. Immunol. , vol.151 , pp. 2453-2461
    • Nelson, A.J.1    Hosier, S.2    Brady, W.3    Linsley, P.S.4    Farr, A.G.5
  • 49
    • 0027957577 scopus 로고
    • Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28
    • Punt, J.A., B.A. Osborne, Y. Takahama, S.O. Sharrow, and A. Singer. 1994. Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28. J. Exp. Med. 179:709-713.
    • (1994) J. Exp. Med. , vol.179 , pp. 709-713
    • Punt, J.A.1    Osborne, B.A.2    Takahama, Y.3    Sharrow, S.O.4    Singer, A.5
  • 50
    • 0030066656 scopus 로고    scopus 로고
    • CD28 expression is not essential for positive and negative selection of thymocytes or peripheral T cell tolerance
    • Walunas, T.L., A.I. Sperling, R. Khattri, C.B. Thompson, and J.A. Bluestone. 1996. CD28 expression is not essential for positive and negative selection of thymocytes or peripheral T cell tolerance. J. Immunol. 156:1006-1013.
    • (1996) J. Immunol. , vol.156 , pp. 1006-1013
    • Walunas, T.L.1    Sperling, A.I.2    Khattri, R.3    Thompson, C.B.4    Bluestone, J.A.5


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