Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes

Journal of Biological Chemistry

Volumn 274, Issue 24, 1999, Pages 17325-17333

  Li, Jianrong ^a   Bombeck, Christopher A ^a   Yang, Sufang ^a   Kim, Young Myeong ^a,b   Billiar, Timothy R ^a,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b Kangwon National University   (South Korea)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CASPASE 3; ENZYME PRECURSOR; NITRIC OXIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL PROTECTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; LIVER CELL; LIVER MITOCHONDRION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELLS, CULTURED; CYTOCHROME C GROUP; DACTINOMYCIN; ENZYME ACTIVATION; LIVER; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033546165     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.24.17325     Document Type: Article

References (51)

1. Steller, H. (1995) Science 267, 1445-1462
2. Jacobson, M. D., Weil, M., and Raff, M. C. (1997) Cell 88, 347-354
3. Thompson, C. B. (1995) Science 267, 1456-1460
4. Thornberry, N. A., and Lazebnik, Y. (1998) Science 281, 1312-1316
5. Green, D. R., and Reed, J. C. (1998) Science 281, 1309-1312
6. Ahmad, M., Srinivasula, S. M., Hegde, R., Mukattaah, R., Fernandes-Alnemri, T., and Alnemri, E. S. (1998) Cancer Res. 58, 5201-5205
7. Hu, S., Snipas, S. J., Vincenz, C., Salvesen, G., and Dixit, V. M. (1998) J. Biol. Chem. 273, 29648-29653
8. Hakem, R., Hakem, A., Duncan, G. S., Henderson, J. T., Woo, M., Soengas, M. S., Elia, A., de la Pompa, J. L., Kagi, D., Khoo, W., Potter, J., Yoshida, R., Kaufman, S. A., Lowe, S. W., Penninger, J. M., and Mak, T. W. (1998) Cell 94, 339-352
9. Luo, X., Budihardjo, I., Zou, H., Slaughter, C., and Wang, X. (1998) Cell 94, 481-490
10. Li, H., Zhu, H., Xu, C. J., and Yuan, J. (1998) Cell 94, 491-501
11. Marzo, I., Brenner, C., Zamzami, N., Jurgensmeier, J. M., Susin, S. A., Vieira, H. L., Prevost, M. C., Xie, Z., Matsuyama, S., Reed, J. C., and Kroemer, G. (1998) Science 281, 2027-2031
12. Susin, S. A., Zamzami, N., and Kroemer, G. (1998) Biochim. Biophys. Acta 1368, 151-165
13. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. (1997) Cell 91, 479-489
14. Sciorati, C., Rovere, P., Ferrarini, M., Heltai, S., Manfredi, A. A., and Clementi, E. (1997) J. Biol. Chem. 272, 23211-23215
15. Mannick, J. B., Asano, K, Izumi, K., Kieff, E., and Stamler, J. S. (1994) Cell 79, 1137-1146
16. Dimmeler, S., Haendeler, J., Nehls, M., and Zeiher, A. M. (1997) J. Exp. Med. 185, 601-607
17. Hebestreit, H., Dibbert, B., Balatti, I., Braun, D., Schapowal, A., Blaser, K., and Simon, H.-U. (1998) J. Exp. Med. 187, 415-425
18. Genaro, A. M., Hortelano, S., Alvarez, A., Martinez, C., and Bosca, L. (1995) J. Clin. Invest. 95, 1884-1890
19. Mannick, J. B., Miao, X. Q., and Stamler, J. S. (1997) J. Biol. Chem. 272, 24125-24128
20. Dimmeler, S., Haendeler, J., Sause, A., and Zeiher, A. M. (1998) Cell Growth Differ. 9, 415-422
21. Farinelli, S. E., Park, D. S., and Greene, L. A. (1996) J. Neurosci. 16, 2325-2334
22. Estevez, A. G., Spear, N., Thompson, J. A., Cornwell, T. L., Radi, R., Barbeito, L., and Bechman, J. S. (1998) J. Neuroscience 18, 3708-3714
23. Chun, S. Y., Eisenhauer, K. M., Kubo, M., and Hsueh, A. J. (1995) Endocrinology 136, 3120-3127
24. Kim, Y.-M., Talanian, R. V., and Billiar, T. R. (1997) J. Biol. Chem. 272, 31138-31148
25. Tzeng, E., Billiar, T. R., Williams, D. L., Li, J., Lizonova, A., Kovesdi, I., and Kim, Y.-M. (1998) Surgery 124, 278-283
26. Li, J., Billiar, T. R., Talanian, R. V., and Kim, Y. M. (1997) Biochem. Biophys. Res. Commun. 240, 419-424
27. Kim, Y. M., de Vera, M. E., Watkins, S. C., and Billiar, T. R. (1997) J. Biol. Chem. 272, 1402-1411
28. Stadler, J., Bergonia, H. A., Di Silvio, M., Sweetland, M. A., Billiar, T. R., Simmons, R. L., and Lancaster, J. R., Jr. (1993) Arch. Biochem. Biophys. 302, 4-11
29. Shears L. L., Kawaharada N., Tzeng, E., Billiar, T. R., Watkins, S. C., Kovesdi, I., Lizonova, A., and Pham, S. M. (1997) J. Clin. Invest. 100, 2035-2042
30. Faleiro, L., Kobayashi, R., Fearnhead, H., and Lazebnik, Y. (1997) EMBO J. 16, 2271-2281
31. Hoefer Scientific Instruments (1994) Protein Electrophoresis Application Guide, pp. 65-75, Hoefer Scientific Instruments, San Francisco, CA
32. Nicoletti, I., Migliorati, G., Pagliacci, M. C., Grignani, F., and Riccardi, C. (1991) J. Immunol. Methods 139, 271-279
33. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T.-I., Jones, D. P., and Wang, X. (1997) Science 275, 1129-1132
34. Leist, M., Gantner, F., Bohlinger, I., Germann, P. G., Tiegs, G., and Wendel, A. (1994) J. Immunol. 153, 1778-1788
35. Ashkenazi, A., and Dixit, V. M. (1998) Science 281, 1305-1308
36. Kuwana, T., Smith, J. J., Muzio, M., Dixit, V., Newmeyer, D. D., and Kornbluth, S. (1998) J. Biol. Chem. 273, 16589-16594
37. Faubion, W. A., Guicciardi, M. E., Miyoshi, H., Bronk, S. F., Roberts, P. J., Svingen, P. A., Kaufmann, S. H., and Gores, G. J. (1999) J. Clin. Invest. 103, 137-145
38. Sweeney, E. A., Inokuchi, J., and Igarashi, Y. (1998) FEBS Lett. 425, 61-65
39. Inayat-Hussain, S. H., Couet, C., Cohen, G. M., and Cain, K. (1997) Hepatology 25, 1516-1526
40. Jones, R. A., Johnson, V. L., Buck, N. R., Dobrota, M., Hinton, R. H., Chow, S. C., and Kass, G. E. N. (1998) Hepatology 27, 1632-1642
41. Jaeschke, H., Fisher, M. A., Lawson, J. A., Simmons, C. A., Farhood, A., and Jones, D. A. (1998) J. Immunol. 160, 3480-3486
42. Talanian, R. V., Quinlan, C., Trautz, S., Hackett, M. C., Mankovich, J. A., Banach, D., Ghayur, T., Brady, K. D., and Wong, W. W. (1997) J. Biol. Chem. 272, 9677-9682
43. Thornberry, N. A., Rano, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M., Houtzager, V. M., Nordstrom, P. A., Roy, S., Vaillancourt, J. P., Chapman, K. T., and Nicholson, D. W. (1997) J. Biol. Chem. 272, 17907-17911
44. Susin, S. A., Zamzami, N., Castedo, M., Daugas, E., Wang, H.-G., Geley, S., Fassy, F., Reed, J. C., and Kroemer, G. (1997) J. Exp. Med. 186, 25-37
45. Zhivotovsky, B., Orrenius, S., Brustugun, O. T., and Doskeland, S. O. (1998) Nature 391, 449-450
46. Bossy-Wetzel, E., Newmeyer, D. D., and Green, D. R. (1998) EMBO J. 17, 37-49
47. Green, D., and Kroemer, G. (1998) Trends Cell Biol 8, 267-271
48. Saavedra, J. E., Billiar, T. R., Williams, D. L., Kim, Y. M., Watkins, S. C., and Keefer, L. K. (1997) J. Med. Chem. 40, 1947-1954
49. Ou, J., Carlos, T. M., Watkins, S. C., Saavedra, J. E., Keefer, L. K., Kim, Y. M., Harbrecht, B. G., and Billiar, T. R. (1997) Nitric Oxide 1, 404-416
50. Cheng, E. H., Kirsch, D. G., Clem, R. J., Ravi, R., Kastan, M. B., Bedi, A., Ueno, K., and Hardwick, J. M. (1997) Science 278, 1966-1968
51. Clem, R. J., Cheng, E H., Karp, C. L., Kirsch, D. G., Ueno, K., Takahashi, A., Kastan, M. B., Griffin, D. E., Earnshaw, W. C., Veliuona, M. A., and Hardwick, J. M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 554-559